Effects of atorvastatin on the function of Tenon ’s capsule fibroblasts in human eyes
ConclusionsATO could inhibit the proliferation and migration of HTFs and induce their apoptosis. It was preliminary proven that ATO could inhibit the signaling pathway induced by TGF- β. It is suggested that ATO could be a basis for the treatment of the scarring of filtration channels after glaucoma surgery. (Source: International Ophthalmology)
Source: International Ophthalmology - July 8, 2023 Category: Opthalmology Source Type: research
Impact of an email advice service on filtering and refining ophthalmology referrals in England
ConclusionA secure email advice service is a safe and low-maintenance modality that provides direct and efficient two-way communication between primary and secondary eye care professionals. It allows rapid response to clinical queries, referral filtering and refinement, and streamlining of patient referral pathways. Users (predominantly optometrists) were overwhelmingly positive about its usefulness in clinical practice. (Source: International Ophthalmology)
Source: International Ophthalmology - July 8, 2023 Category: Opthalmology Source Type: research
Myopia control: short-term effect of 0.01% atropine vs. defocus incorporated multiple segment lenses —a retrospective study in European children
ConclusionComparison between 0.01% atropine eyedrops and DIMS spectacle lenses for slowing the progression of myopia favored DIMS lenses in terms of AL elongation in a short-term follow-up. There was no difference in terms of SE between groups. (Source: International Ophthalmology)
Source: International Ophthalmology - July 7, 2023 Category: Opthalmology Source Type: research
Circulating miRNAs and their functional genetic variants in pseudoexfoliative glaucoma: potential of miR-146a-5p as a diagnostic biomarker
ConclusionsCirculating miR-146a-5p can contribute to the risk of PEX/PEG. Therefore, we propose that plasma miR-146a-5p can be developed as a potential biomarker for the minimally invasive diagnoses of PEX/PEG and as a potential therapeutic target with further studies. (Source: International Ophthalmology)
Source: International Ophthalmology - July 7, 2023 Category: Opthalmology Source Type: research
The evaluation of the skin-muscle and only-skin upper blepharoplasty featuring surface electromyography: a single-masked, randomized split-face prospective study
ConclusionsThis study is an objective and quantitative report using surface electromyography on upper blepharoplasty with or without a strip of OOM excision. Our results showed that OOM fully recovers after the stripping procedure. The resection of the skin-OOM flap showed no difference in long-term cosmetic results. Therefore, we recommend OOM preservation during upper blepharoplasty unless muscle excision is well-grounded. (Source: International Ophthalmology)
Source: International Ophthalmology - July 7, 2023 Category: Opthalmology Source Type: research
Is there room for prompt routine ophthalmic examination in neonates with congenital cytomegalovirus (CMV) infection during the neonatal period?
ConclusionThe presence of ophthalmological findings among neonates with congenital CMV infection during the neonatal period is infrequent, suggesting that routine ophthalmological screening may be safely deferred for the post-neonatal period. (Source: International Ophthalmology)
Source: International Ophthalmology - July 7, 2023 Category: Opthalmology Source Type: research
Optimizing glucocorticoid therapy for Beh çet's uveitis: efficacy, adverse effects, and advances in combination approaches
AbstractBeh çet's uveitis (BU) is a debilitating manifestation of Behçet's disease, often requiring prompt and aggressive treatment to prevent vision loss. Glucocorticoids (GCS) serve as a first-line therapy for BU; however, their long-term, high-dose use can result in significant adverse effects. This review summarizes the efficacy, adverse effects, and advances in combination therapy involving GCS for the management of BU. We discuss the benefits and drawbacks of various GCS administration routes, including periocular and intravitreal injections, intravitreal sustained-release devices, and systemic th erapy, highlighti...
Source: International Ophthalmology - July 7, 2023 Category: Opthalmology Source Type: research
Fundus autofluorescence in uveitis: from pathogenesis to imaging interpretation
ConclusionsFAF serves to understand pathophysiologic mechanisms of uveitis and is a valuable prognostic indicator of themselves. (Source: International Ophthalmology)
Source: International Ophthalmology - July 7, 2023 Category: Opthalmology Source Type: research
Application of topical 2% cyclosporine A in inflammatory ocular surface diseases
ConclusionsTopical 2% CsA may address the needs of different cases with ocular surface inflammation, as a safe option for long-term therapy. (Source: International Ophthalmology)
Source: International Ophthalmology - July 7, 2023 Category: Opthalmology Source Type: research
Ab-externo canaloplasty with and without suture in highly myopic eyes
ConclusionAb-externo canaloplasty performed either with or without a tensioning suture demonstrated good effectiveness in highly myopic eyes with a significant reduction in IOP and number of anti-glaucoma medications. The suture group achieved a lower postoperative IOP. However, the no-suture modification provides a similar reduction in medications with reduced tissue handling. (Source: International Ophthalmology)
Source: International Ophthalmology - July 6, 2023 Category: Opthalmology Source Type: research
Short-term changes detected by corneal topography and optical coherence tomography after prophylactic laser iridotomy in primary angle closure suspect
ConclusionOur results suggest that LPI in patients with PACS provides improved retinal thickness and RNFL thickness, as well as anterior chamber parameters. (Source: International Ophthalmology)
Source: International Ophthalmology - July 6, 2023 Category: Opthalmology Source Type: research
Subjective patient-reported visual quality after small-incision lenticule extraction and its correlation to the objective one
ConclusionThe high patient-reported satisfaction confirmed the ideal effect on visual quality following SMILE in real-life situations, though some objective optical performances were not satisfying. It is very tolerant toward patients ’ conditions and mild deviations, and this study did not find factors affecting visual performances. (Source: International Ophthalmology)
Source: International Ophthalmology - July 6, 2023 Category: Opthalmology Source Type: research
Comparison of the results of the modified and classical bi-medial hang-back recession in infantile esotropia
ConclusionsThis modified novel technique aims to avoid unwanted muscle movement in the horizontal and vertical axes and a gap in the middle of the recessed muscle, as seen in the traditional hang-back technique. Further, the modified technique resulted in less over- and under-correction as well as alphabetic pattern deviation. (Source: International Ophthalmology)
Source: International Ophthalmology - July 6, 2023 Category: Opthalmology Source Type: research
Low-dose rosmarinic acid and thymoquinone accelerate wound healing in retinal pigment epithelial cells
ConclusionLow doses of RA and TQ were clearly demonstrated to have protective properties against possible damage to retinal pigment epithelial cells. (Source: International Ophthalmology)
Source: International Ophthalmology - July 5, 2023 Category: Opthalmology Source Type: research
Vector analysis of astigmatism correction after PRK, FS-LASIK, and SMILE for myopic astigmatism
ConclusionsOne-year outcomes revealed that PRK, FS-LASIK, and SMILE were all equally effective in correcting myopic astigmatism. However, FS-LASIK demonstrated more favorable astigmatism correction in eyes with astigmatism > 1.00D in early postoperatively. (Source: International Ophthalmology)
Source: International Ophthalmology - July 5, 2023 Category: Opthalmology Source Type: research
