Does the introduction of streamlight decrease refractive surgery operating time?
ConclusionThe introduction of transepithelial PRK did not bring significant time-associated savings into the refractive surgery suite. (Source: International Ophthalmology)
Source: International Ophthalmology - April 18, 2024 Category: Opthalmology Source Type: research

Efficacy, safety and cost-effectiveness of 5-fluorouracil versus interferon α-2b as adjuvant therapy after surgery in ocular surface squamous neoplasia in a southern European tertiary hospital
ConclusionsBoth 5-FU and IFN α-2b are effective and present a good security profile as adjuvant therapies after surgery in OSSN. Although presenting slightly more ocular complications, 5-FU can be considered more cost-effective than IFN α-2b. (Source: International Ophthalmology)
Source: International Ophthalmology - April 17, 2024 Category: Opthalmology Source Type: research

Changes in ocular blood flow in patients with neovascular age-related macular degeneration after intravitreal injection of ranibizumab biosimilar and brolucizumab
ConclusionOur findings suggest that the short-term impact on OBF varies depending on the drug used for nAMD. (Source: International Ophthalmology)
Source: International Ophthalmology - April 16, 2024 Category: Opthalmology Source Type: research

Effect of mindfulness-based stress reduction on acute central serous chorioretinopathy: a randomized control trial
ConclusionMBSR may have beneficial outcomes in the early treatment of patients with CSCR, resulting in faster resolution of subretinal fluid and enhancement of BCVA. (Source: International Ophthalmology)
Source: International Ophthalmology - April 16, 2024 Category: Opthalmology Source Type: research

Susceptibility of optic nerve head in children with posture-related elevation of intraocular pressure
ConclusionPosture-dependent IOP elevations do not seem to influence retinal nerve fibre layer thickness or Bruch membrane opening-based morphometric data in childhood. (Source: International Ophthalmology)
Source: International Ophthalmology - April 16, 2024 Category: Opthalmology Source Type: research

Macular hole surgery follow-up with spectral domain-optical coherence tomography-guided facedown posturing
ConclusionsOCT-guided FDP approach yields excellent closure rates with no late complications and ensures good patient comfort. (Source: International Ophthalmology)
Source: International Ophthalmology - April 16, 2024 Category: Opthalmology Source Type: research

Efficacy of tocilizumab in patients with moderate-to-severe corticosteroid-resistant thyroid eye disease: a prospective study
ConclusionTCZ can treat active moderate-to-severe TED, showing high drug compliance and reasonable response to inflammation and extraocular motility abnormality. (Source: International Ophthalmology)
Source: International Ophthalmology - April 16, 2024 Category: Opthalmology Source Type: research

Comparison of macular and optic disc vessel density in thyroid orbitopathy: a comparative octa study
ConclusionActive TO group had lower vessel density than inactive group and after treatment, vessel density was increased. Non-invasive quantitative analysis of retinal and optic disc perfusion using OCTA could be useful in early treatment before complications occur and monitoring patients with TO. (Source: International Ophthalmology)
Source: International Ophthalmology - April 15, 2024 Category: Opthalmology Source Type: research

Ocular manifestations of liver disease: an important diagnostic aid
ConclusionsBuilding strong associations between ocular and liver pathology will allow for early detection of such conditions, leading to the early implementation of management strategies. While this review outlines several of the existing connections between hepatic and ophthalmic disease, further research is needed in the area in order to strengthen these associations. (Source: International Ophthalmology)
Source: International Ophthalmology - April 15, 2024 Category: Opthalmology Source Type: research

Identification of a circulating three-miRNA panel for the diagnosis of primary open angle glaucoma
ConclusionsIn conclusion, we built and identified a circulating three-miRNA panel as a potential diagnostic biomarker for POAG. It may be developed into an efficient assay and help improve the POAG diagnosis in the future. (Source: International Ophthalmology)
Source: International Ophthalmology - April 15, 2024 Category: Opthalmology Source Type: research

Efficacy of  hydroxypropyl-guar drops in improving tear film index and ocular surface dynamics using two treatment methods under a controlled desiccating environment
ConclusionHp-guar drops significantly improve tear film parameters under a desiccating environment, however, tear film parameters respond differently to the management modalities. In the protection method, tear film osmolarity was protected against a dry environment, while in the relief mode, an improvement in tear production and a decrease in ocular surface temperature were seen. Hp-guar performance could be maximized for the management of exposure to adverse environments by using a treatment protocol that targets the most affected parameters in each group of patients. Using CEC has the potential to provide researchers wi...
Source: International Ophthalmology - April 14, 2024 Category: Opthalmology Source Type: research

Diagnosis of retinal damage using Resnet rescaling and support vector machine (Resnet-RS-SVM): a case study from an Indian hospital
ConclusionThe findings demonstrate the effectiveness of the ResNet-RS-SVM model in accurately identifying retinal damage in diverse datasets collected from multiple eye hospitals in India. This approach presents a promising advancement in computer-aided diagnosis for improving the detection and management of retinal diseases. (Source: International Ophthalmology)
Source: International Ophthalmology - April 13, 2024 Category: Opthalmology Source Type: research

Axonal protection by combination of ripasudil and brimonidine with upregulation of p-AMPK in TNF-induced optic nerve degeneration
ConclusionThe combination of ripasudil and brimonidine may have additive protective effects compared with single-agent treatment alone. These protective effects may be at least partially associated with AMPK activation. (Source: International Ophthalmology)
Source: International Ophthalmology - April 10, 2024 Category: Opthalmology Source Type: research

Higher order aberrations in keratoconus ‏
ConclusionsEarly diagnosis can lead to early treatment and may allow for arresting progression, thereby improving the long-term prognosis. With the acceleration of refractive surgery, it is important to identify patients with keratoconus, as they are usually contraindicated for refractive surgery. (Source: International Ophthalmology)
Source: International Ophthalmology - April 10, 2024 Category: Opthalmology Source Type: research

Dynamic viscosity of the wall of the lacrimal sac in disorders of the patency of the lacrimal ducts
ConclusionBiomechanical properties of the lacrimal sac may vary depending on the cause of obliteration of the lacrimal ducts. The integrated dynamic viscosity is significantly higher in SALDO patients due to exposure to radioiodine compared to that in PANDO patients. (Source: International Ophthalmology)
Source: International Ophthalmology - April 8, 2024 Category: Opthalmology Source Type: research