Assessment of the iridocorneal angle pigmentation and structures after the implantation of EVO+ Visian Implantable Collamer Lens
ConclusionsThe EVO+ ICL implantation after uneventful procedures appears not to clinically affect the iridocorneal angle pigmentation and/or structures during a short-medium follow-up using gonioscopy assessment. The intra-rater reliability of glaucoma specialists assessing iridocorneal angle structures using gonios copy images is very high. (Source: International Ophthalmology)
Source: International Ophthalmology - September 11, 2023 Category: Opthalmology Source Type: research
Probucol attenuates high glucose-induced M üller cell damage through enhancing the Nrf2/p62 signaling pathway
ConclusionsOur results suggest that probucol may protect M üller cells from HG-induced damage through enhancing the Nrf2/p62 signaling pathway. (Source: International Ophthalmology)
Source: International Ophthalmology - September 9, 2023 Category: Opthalmology Source Type: research
Evaluation of recovery time of tear film function and ocular surface after discontinuing oral isotretinoin treatment for acne vulgaris
ConclusionDry eye disease can return to baseline levels after treatment withdrawal. At least 6 weeks later, they could wear contact lenses again, and it was useful to prepare all patients requiring further ocular surgery. (Source: International Ophthalmology)
Source: International Ophthalmology - September 9, 2023 Category: Opthalmology Source Type: research
Identification and validation of an immune-relevant risk signature predicting survival outcome and immune infiltration in uveal melanoma
ConclusionThe identified immune risk signature was demonstrated to be associated with the favorable immune infiltration, prognosis and immunotherapeutic efficacy, which may provide clues for survival evaluation and immune treatment. (Source: International Ophthalmology)
Source: International Ophthalmology - September 9, 2023 Category: Opthalmology Source Type: research
HIF1 α and HIF2α immunoreactivity in epithelial tissue of primary and recurrent pterygium by immunohistochemical analysis
ConclusionOur study shows evidence that the higher expressed epithelialHIF2 α, rather thanHIF1 α, and the balance between both HIF isoforms might be relevant factors associated with pathogenesis of primary pterygium. Modulation ofHIF2 α levels and activity may thus offer a new therapeutic approach to the treatment of advancing pterygium where the initial stage with its HIF1-peak has already passed. (Source: International Ophthalmology)
Source: International Ophthalmology - September 8, 2023 Category: Opthalmology Source Type: research
Allergen-specific IgE in the tear fluid of Chinese patients with common allergic conjunctivitis in autumn and winter
ConclusionIn autumn and winter, the most common AC allergen in Chinese patients was house dust mites. Compared with systemic allergen tests, measuring specific IgE in tears may be a non-invasive method to diagnose and evaluate AC severity, which may be more suitable to reflect the local conditions of ocular surface inflammation due to its high positive rate and convenience. (Source: International Ophthalmology)
Source: International Ophthalmology - September 5, 2023 Category: Opthalmology Source Type: research
Herpes simplex virus keratitis: electronic medical records driven big data analytics report from a tertiary eye institute of South India
ConclusionBased on our institute-based data, the most common type of HSV keratitis is Immune stromal keratitis followed by epithelial keratitis. Although not representative of the general population, this data provide useful insights related to HSV keratitis from India. (Source: International Ophthalmology)
Source: International Ophthalmology - September 5, 2023 Category: Opthalmology Source Type: research
Comparison of a new implantable collamer lens formula to standards formulas using spectral domain optical coherence tomography
ConclusionSD-OCT data with OCOS result in good postoperative vaults. Further refinement is required to the NK2 for use with SD-OCT data. Although the EPB formula provides acceptable predicted vaults, further refinement with a larger sample size is needed. (Source: International Ophthalmology)
Source: International Ophthalmology - September 4, 2023 Category: Opthalmology Source Type: research
Safety of YAG laser vitreolysis for intraocular tissues: analysis of postoperative complications
ConclusionYAG laser vitreolysis is safe when the distance is more than 2 mm from ablation point to the lens and the retina, and the total energy is less than 2000 mJ for one treatment procedure. (Source: International Ophthalmology)
Source: International Ophthalmology - September 4, 2023 Category: Opthalmology Source Type: research
Effect of the iridocorneal angle size on the diurnal pressure profile in a glaucoma suspect cohort and patients with glaucoma
ConclusionAn ICAS of larger than 10 ° in HCG or glaucoma patients with an open-angle does not influence the minimum, average, maximum or range of IOP. Additionally, an angle size larger than 10° does not allow the prediction of IOP changes in these two cohorts. (Source: International Ophthalmology)
Source: International Ophthalmology - September 2, 2023 Category: Opthalmology Source Type: research
Late-onset distal-apical intracorneal ring-segments keratopathy: an analysis of a large sample in a multicenter study
ConclusionsA late-onset distal-apical ICRS keratopathy was detected with low prevalence (0.24%) in a large sample. It was classified into three stages according to its severity. Different treatments were selected for each stage, obtaining stable results 1 year after treatment. (Source: International Ophthalmology)
Source: International Ophthalmology - August 2, 2023 Category: Opthalmology Source Type: research
Real-world outcomes of intravitreal bevacizumab treat-and-extend for cystoid macular oedema secondary to central retinal vein occlusion
ConclusionThe use of intravitreal bevacizumab in a treat-and-extend regimen is effective in treating CMO secondary to CRVO, in a real-world setting. (Source: International Ophthalmology)
Source: International Ophthalmology - July 22, 2023 Category: Opthalmology Source Type: research
Changes of dysfunctional lens index before and after implantable collamer lens V4c implantation in patients with moderate-to-high myopia
ConclusionsThe postoperative refractive parameters were confirmed excellent in efficacy, predictability, and stability in half a year. The DLI was significantly improved after the ICL V4c implantation in patients with moderate-to-high myopia and showed good stability during the follow-up periods. The DLI deserves a more comprehensive understanding and application in clinical services. (Source: International Ophthalmology)
Source: International Ophthalmology - July 22, 2023 Category: Opthalmology Source Type: research
The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
ConclusionBoth PCPIOLs and ACPIOLs are comparably safe and efficient options in management of KCN and their efficacy significantly improves when combined with CXL/ICRS. (Source: International Ophthalmology)
Source: International Ophthalmology - July 20, 2023 Category: Opthalmology Source Type: research
Diagnostic efficacy of elevated serum angiotensin-converting enzyme and lymphopenia between presumed sarcoid uveitis and presumed tubercular uveitis
ConclusionElevated sACE activity was an independent risk factor for presumed sarcoid uveitis over lymphopenia alone or in combination with lymphopenia. (Source: International Ophthalmology)
Source: International Ophthalmology - July 19, 2023 Category: Opthalmology Source Type: research
