Filtered By:
Procedure: Gastroschisis Repair
This page shows you your search results in order of date. This is page number 9.
Order by Relevance | Date
Total 964 results found since Jan 2013.
Light Emitting Diodes Irradiation Regulates miRNA-877-3p to Promote Cardiomyocyte Proliferation
Int J Med Sci. 2022 Jul 11;19(8):1254-1264. doi: 10.7150/ijms.70743. eCollection 2022.ABSTRACTMammalian cardiomyocytes (CMs) maintain a low capacity for self-renewal in adulthood, therefore the induction of CMs cycle re-entry is an important approach to promote myocardial repair after injury. Recently, photobiomodulation (PBM) has been used to manipulate physiological activities of various tissues and organs by non-invasive means. Here, we demonstrate that conditioned PBM using light-emitting diodes with a wavelength of 630 nm (LED-Red) was capable of promoting the proliferation of neonatal CMs. Further studies showed that...
Source: International Journal of Medical Sciences - August 5, 2022 Category: Biomedical Science Authors: Xinlu Gao Hanjing Li Xiuxiu Wang Zhongyu Ren Yanan Tian Jingxuan Zhao Wenyi Qi Hongbo Wang Ying Yu Rui Gong Hongyang Chen Haoyu Ji Fan Yang Wenya Ma Yu Liu Source Type: research
Downregulation of DNA methyltransferase-3a ameliorates the osteogenic differentiation ability of adipose-derived stem cells in diabetic osteoporosis via Wnt/ β-catenin signaling pathway
CONCLUSIONS: Dnmt3a silencing rescues the negative effects of DOP on ASCs and provides a possible approach for bone tissue regeneration in patients with diabetic osteoporosis.PMID:35927735 | DOI:10.1186/s13287-022-03088-4
Source: Cell Research - August 4, 2022 Category: Cytology Authors: Maorui Zhang Yujin Gao Qing Li Huayue Cao Jianghua Yang Xiaoxiao Cai Jingang Xiao Source Type: research
622 Regulation of XPC binding dynamics and global nucleotide excision repair by p63 and vitamin D receptor
p63 and the vitamin D receptor (VDR) play important roles in epidermal development and differentiation, but their roles and relationship in the response to ultraviolet (UV) radiation are unclear. Using TERT-immortalized human keratinocytes expressing shRNA targeting p63 in concert with exogenously applied siRNA targeting VDR, we assessed p63 and VDR ’s separate and combined effect on nucleotide excision repair (NER) of UV-induced 6-4 photoproducts (6-4PP) with a focus on the XPC DNA damage recognition protein.
Source: Journal of Investigative Dermatology - July 20, 2022 Category: Dermatology Authors: C. Wong, D.H. Oh Source Type: research
Targeting HER3-dependent activation of nuclear AKT improves radiotherapy of non-small celllung cancer
CONCLUSION: IR-induced activation of nuclear AKT occurs inside the nucleus that is mainly dependent on HER3 expression in NSCLC. These findings suggest that targeting HER3 in combination with radiotherapy may provide a logical treatment option for investigation in selected NSCLC patients.PMID:35839938 | DOI:10.1016/j.radonc.2022.07.008
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - July 15, 2022 Category: Radiology Authors: Mahmoud Toulany Mari Iida Konstanze Lettau John P Coan Simone Rebholz Shayan Khozooei Paul M Harari Deric L Wheeler Source Type: research
Inhibition of the translation initiation factor eIF4A enhances tumor cell radiosensitivity
Mol Cancer Ther. 2022 Jun 23:molcanther.0037.2022. doi: 10.1158/1535-7163.MCT-22-0037. Online ahead of print.ABSTRACTA fundamental component of cellular radioresponse is the translational control of gene expression. As a critical regulator of translational control is the eIF4F cap binding complex, we investigated whether eIF4A, the RNA helicase component of eIF4F, can serve as a target for radiosensitization. Knockdown of eIF4A using siRNA reduced translational efficiency, as determined from polysome profiles, and enhanced tumor cell radiosensitivity as determined by clonogenic survival. The increased radiosensitivity was ...
Source: Cancer Control - June 22, 2022 Category: Cancer & Oncology Authors: Stacey L Lehman Theresa Wechsler Kayla Schwartz Lauren E Brown John A Porco William G Devine Jerry Pelletier Uma T Shankavaram Kevin Camphausen Philip J Tofilon Source Type: research
CD44 Mediates Oral Squamous Cell Carcinoma-Promoting Activity of MRE11 via AKT Signaling
In this study, we aimed to investigate the engagement of CD44, a cancer stemness marker functioning in the control of cell growth and motility, in OSCC malignancy under the influence of MRE11. We found that overexpression of MRE11 enhanced CD44 expression and tumorsphere formation in OSCC cells, whereas knockdown of MRE11 reduced these phenomena. In addition, the MRE11-promoted tumorsphere formation or cell migration ability was compromised in OSCC cells carrying siRNA that targets CD44, as was the MRE11-promoted AKT phosphorylation. These were further supported by analyzing clinical samples, where higher CD44 expression w...
Source: Cancer Control - May 28, 2022 Category: Cancer & Oncology Authors: Shyng-Shiou F Yuan Amos C Hung Ching-Wei Hsu Ting-Hsun Lan Chang-Wei Su Tsung-Chen Chi Yu-Chiuan Chang Yuk-Kwan Chen Yen-Yun Wang Source Type: research
