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Professional development through mentoring: Final evaluation of the pilot mentoring programme of the European society of radiotherapy and oncology
Radiother Oncol. 2024 Mar 14:110226. doi: 10.1016/j.radonc.2024.110226. Online ahead of print.ABSTRACTThe European SocieTy for Radiotherapy and Oncology (ESTRO) organized a one-year pilot mentoring programme. At evaluation after one year, both mentors and mentees scored the programme with a median score of 9 on a scale of 10. All of the mentors indicated that they wanted to participate again as mentors.PMID:38492670 | DOI:10.1016/j.radonc.2024.110226 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 16, 2024 Category: Radiology Authors: Steven F Petit Daniel Portik Azadeh Abravan Jenny Bertholet Dylan Callens Ludwig Dubois Pierfrancesco Franco Morten Horsholt Kristensen Pierre Montay-Gruel Daan Nevens Sophie Perryck Kathrine R øe Redalen Bart łomiej Tomasik Amanda Webster Jesper Grau E Source Type: research

ESTRO-SIOPE guideline: Clinical management of radiotherapy in atypical teratoid/rhabdoid tumors (AT/RTs)
CONCLUSION: The present guideline summarizes the evidence and clinical-based recommendations for RT in patients with AT/RT. Prospective clinical trials and international, large registries evaluating modern treatment approaches will contribute to a better understanding of the best treatment for these children in future.PMID:38492671 | DOI:10.1016/j.radonc.2024.110227 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 16, 2024 Category: Radiology Authors: Beate Timmermann Claire Alapetite Karin Dieckmann Rolf-Dieter Kortmann Yasmin Lassen-Ramshad John H Maduro Monica Ramos Albiac Umberto Ricardi Damien C Weber Source Type: research

Clinical practicality and patient performance for surface-guided automated VMAT gating for DIBH breast cancer radiotherapy
CONCLUSION: Independent of the use of audio-coaching, this study demonstrates that automated surface-guided gating with DIBH and VMAT proved highly efficient. Patients' DIBH performance far exceeded our expectations compared to earlier experiences and literature. Furthermore, gating window tolerances could be reduced.PMID:38492672 | DOI:10.1016/j.radonc.2024.110229 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 16, 2024 Category: Radiology Authors: Sophie Huijskens Patrick Granton Kimm Fremeijer Cynthia van Wanrooij Kirsten Offereins-van Harten Suzanne Schouwenaars-van den Beemd Mischa Hoogeman Margriet G A Sattler Joan Penninkhof Source Type: research

Proposals for the delineation of neck clinical target volume for definitive Radiation therapy in patients with oral/ oropharyngeal squamous cell cancer based on lymph node distribution
CONCLUSION: This is the first description of LN topographic spread patterns for OSCC/OPSCC. Modified CTV for prophylactic irradiation was proposed to spare the organs at risk and minimize adverse effects.PMID:38490491 | DOI:10.1016/j.radonc.2024.110225 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 15, 2024 Category: Radiology Authors: Yun-Chang Liu Xin Zhang Hao-Nan Yang Lu Zhang Dan Li Meng-Qi Yang Nuo-Han Wang Yong-Zhong Wu Jiang-Dong Sui Ying Wang Source Type: research

Proposals for the delineation of neck clinical target volume for definitive Radiation therapy in patients with oral/ oropharyngeal squamous cell cancer based on lymph node distribution
CONCLUSION: This is the first description of LN topographic spread patterns for OSCC/OPSCC. Modified CTV for prophylactic irradiation was proposed to spare the organs at risk and minimize adverse effects.PMID:38490491 | DOI:10.1016/j.radonc.2024.110225 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 15, 2024 Category: Radiology Authors: Yun-Chang Liu Xin Zhang Hao-Nan Yang Lu Zhang Dan Li Meng-Qi Yang Nuo-Han Wang Yong-Zhong Wu Jiang-Dong Sui Ying Wang Source Type: research

Predicting overall survival and prophylactic cranial irradiation benefit in small-cell lung cancer with CT-based deep learning: A retrospective multicenter study
CONCLUSIONS: The CT-based deep learning model exhibited promising performance in predicting the OS of SCLC patients. The OS signature may aid in individualized treatment planning to select patients who may benefit from PCI.PMID:38479441 | DOI:10.1016/j.radonc.2024.110221 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 13, 2024 Category: Radiology Authors: Xiaomin Zheng Kaicai Liu Na Shen Yankun Gao Chao Zhu Cuiping Li Chang Rong Shuai Li Baoxin Qian Jianying Li Xingwang Wu Source Type: research

A systematic review of circulating predictive and prognostic biomarkers to aid the personalised use of radiotherapy in the radical treatment of patients with oesophageal cancer
CONCLUSIONS: There is consistent evidence for the potential predictive and prognostic value of a small number of biomarkers in OSCC and OAC, though these data are insufficient for translation to current clinical practice. Well-designed prospective studies are now required to validate their role in stratified and personalised RT treatment approaches.PMID:38479442 | DOI:10.1016/j.radonc.2024.110224 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 13, 2024 Category: Radiology Authors: Dylan McClurg Chandan Sanghera Somnath Mukherjee Rebecca C Fitzgerald Christopher M Jones Source Type: research

A population-based analysis of the impact of 1 vs. 2 doses of mitomycin on patterns of failure of anal cancer patients treated with concurrent chemoradiotherapy
CONCLUSIONS: Our analysis showed that 1 vs. 2 cycles of MMC along with 5FU and radiation is associated with comparable treatment outcomes in general. However, in patients with stage IIIb and IIIc cancer, 2 doses of MMC were associated with improved ASCC-SS and distant DFS.PMID:38479443 | DOI:10.1016/j.radonc.2024.110219 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 13, 2024 Category: Radiology Authors: Kurian Joseph Zainab Al Habsi Aswin Abraham Arun Elangovan Sunita Ghosh Truo-Mingh Pham Devika Shreekumar Zeyana Ramji Kim Paulson Keith Tankel Nawaid Usmani Diane Severin Dan Schiller Clarence Wong Karen Mulder Hatim Karachiwala Corinne Doll Karen King T Source Type: research

Predicting overall survival and prophylactic cranial irradiation benefit in small-cell lung cancer with CT-based deep learning: A retrospective multicenter study
CONCLUSIONS: The CT-based deep learning model exhibited promising performance in predicting the OS of SCLC patients. The OS signature may aid in individualized treatment planning to select patients who may benefit from PCI.PMID:38479441 | DOI:10.1016/j.radonc.2024.110221 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 13, 2024 Category: Radiology Authors: Xiaomin Zheng Kaicai Liu Na Shen Yankun Gao Chao Zhu Cuiping Li Chang Rong Shuai Li Baoxin Qian Jianying Li Xingwang Wu Source Type: research

A systematic review of circulating predictive and prognostic biomarkers to aid the personalised use of radiotherapy in the radical treatment of patients with oesophageal cancer
CONCLUSIONS: There is consistent evidence for the potential predictive and prognostic value of a small number of biomarkers in OSCC and OAC, though these data are insufficient for translation to current clinical practice. Well-designed prospective studies are now required to validate their role in stratified and personalised RT treatment approaches.PMID:38479442 | DOI:10.1016/j.radonc.2024.110224 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 13, 2024 Category: Radiology Authors: Dylan McClurg Chandan Sanghera Somnath Mukherjee Rebecca C Fitzgerald Christopher M Jones Source Type: research

A population-based analysis of the impact of 1 vs. 2 doses of mitomycin on patterns of failure of anal cancer patients treated with concurrent chemoradiotherapy
CONCLUSIONS: Our analysis showed that 1 vs. 2 cycles of MMC along with 5FU and radiation is associated with comparable treatment outcomes in general. However, in patients with stage IIIb and IIIc cancer, 2 doses of MMC were associated with improved ASCC-SS and distant DFS.PMID:38479443 | DOI:10.1016/j.radonc.2024.110219 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 13, 2024 Category: Radiology Authors: Kurian Joseph Zainab Al Habsi Aswin Abraham Arun Elangovan Sunita Ghosh Truo-Mingh Pham Devika Shreekumar Zeyana Ramji Kim Paulson Keith Tankel Nawaid Usmani Diane Severin Dan Schiller Clarence Wong Karen Mulder Hatim Karachiwala Corinne Doll Karen King T Source Type: research

Dosimetric impact of bone marrow sparing for robustly optimized IMPT for locally advanced cervical cancer
CONCLUSION: Achieving 1 GyRBE BMS for IMPT is feasible for LACC patients with limited dosimetric impact on other OARs. While further bone marrow dose reduction is possible for some patients, it may increase OAR doses substantially for others. Hence, we recommend a personalized approach when introducing BMS into clinical IMPT treatment planning to carefully assess individual patient benefits and risks.PMID:38471634 | DOI:10.1016/j.radonc.2024.110222 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 12, 2024 Category: Radiology Authors: S C Kuipers J Godart A Corbeau S Breedveld J W M Mens S M de Boer R A Nout M S Hoogeman Source Type: research

Dosimetric impact of bone marrow sparing for robustly optimized IMPT for locally advanced cervical cancer
CONCLUSION: Achieving 1 GyRBE BMS for IMPT is feasible for LACC patients with limited dosimetric impact on other OARs. While further bone marrow dose reduction is possible for some patients, it may increase OAR doses substantially for others. Hence, we recommend a personalized approach when introducing BMS into clinical IMPT treatment planning to carefully assess individual patient benefits and risks.PMID:38471634 | DOI:10.1016/j.radonc.2024.110222 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 12, 2024 Category: Radiology Authors: S C Kuipers J Godart A Corbeau S Breedveld J W M Mens S M de Boer R A Nout M S Hoogeman Source Type: research

Optimal hypofractionated radiation therapy schemes for early-stage hepatocellular carcinoma
CONCLUSION: From the fits to the clinical TCP data, we presented the first determination of radiobiological parameters and model-independent optimal fractionation regimens in 1-20 fractions to achieve maximal tumor control whenever safe for SBRT and hypofractionated radiation therapy of early-stage HCC. The determined optimal fractionation schemes agree well with clinical practice for SBRT of early-stage HCC. However, most existing hypofractionated radiation therapy schemes of 3-5 Gy/fraction are not optimal, higher doses are required to maximize tumor control, further validation of these findings is essential with clinica...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 11, 2024 Category: Radiology Authors: Feng Liu Doris R Brown Michael T Munley Source Type: research

Longitudinal changes in the carotid arteries of head and neck cancer patients following radiation therapy: Results from a prospective serial imaging biomarker characterization study
CONCLUSIONS: Functional and morphologic changes of the carotid arteries detected by carotid ultrasound, such as changes in global circumferential strain at 6 months and carotid IMT at 18 months, may be useful for the early detection of radiation-induced carotid artery injury, can guide future research aiming to mitigate carotid artery stenosis, and should be considered for clinical surveillance survivorship recommendations after head and neck RT.PMID:38467343 | DOI:10.1016/j.radonc.2024.110220 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 11, 2024 Category: Radiology Authors: Efstratios Koutroumpakis Abdallah Sherif Radwan Mohamed Peter Chaftari David I Rosenthal Dorothy Gujral Christopher Nutting Serageldin Kamel Mohamed A Naser Peter Kim Roland Bassett Clifton D Fuller Elie Mouhayar MD Anderson Head Neck Radiation Oncology C Source Type: research