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Reirradiation for recurrent gynecologic cancer using high-dose-rate brachytherapy in Japan: A multicenter survey on practice patterns and outcomes
CONCLUSION: Reirradiation with HDR brachytherapy for recurrent gynecologic cancer is effective, especially in cases with a long interval before reirradiation.PMID:38583719 | DOI:10.1016/j.radonc.2024.110269 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 7, 2024 Category: Radiology Authors: Fumiaki Isohashi Ken Yoshida Naoya Murakami Koji Masui Shunichi Ishihara Yu Ohkubo Yuko Kaneyasu Rumiko Kinoshita Tadayuki Kotsuma Yuji Takaoka Eiichi Tanaka Ayaka Nagao Kazuhiko Ogawa Hideya Yamazaki Source Type: research

Long-term efficacy analysis of radiotherapy and local management of metastases in patients with newly diagnosed oligometastatic nasopharyngeal carcinoma: A prospective, single-arm, single-center clinical study
CONCLUSION: Patients with newly diagnosed oligometastatic NPC can achieve long-term survival after receiving radical radiotherapy to the primary site and local treatment for metastases.PMID:38583720 | DOI:10.1016/j.radonc.2024.110265 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 7, 2024 Category: Radiology Authors: Huang Shuang Jiang Feng Cao Caineng Jin Qifeng Jin Ting Hua Yonghong Chen Xiaozhong Source Type: research

Comprehensive radiotherapy for pediatric Ewing Sarcoma: Outcomes of a prospective proton study
CONCLUSION: In conclusion, LC for pediatric patients with EWS treated with PRT was comparable to that of historical patients who received photon-RT. Tumor size ≥ 8 cm predicted increased risk of local failure. Patients with metastatic disease, including non-pulmonary only metastases, received radiation therapy to all metastatic sites and had favorable survival outcomes.PMID:38583721 | DOI:10.1016/j.radonc.2024.110270 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 7, 2024 Category: Radiology Authors: Julianna K Bronk Mary Frances McAleer Susan L McGovern Yasmin Lassen-Ramshad Akmal Safwat Najat C Daw Nino Rainusso Anita Mahajan David R Grosshans Arnold C Paulino Source Type: research

Validated machine learning tools to distinguish checkpoint inhibitor, radiotherapy, COVID-19 and other infective pneumonitis
CONCLUSION: Our results demonstrate the potential utility of such tools as a second or concurrent reader to support oncologists, radiologists, and chest physicians in cases of diagnostic uncertainty. Further research is required for patients with exposure to both ICI and thoracic radiotherapy.PMID:38582181 | DOI:10.1016/j.radonc.2024.110266 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 6, 2024 Category: Radiology Authors: Sumeet Hindocha Benjamin Hunter Kristofer Linton-Reid Thomas George Charlton Mitchell Chen Andrew Logan Merina Ahmed Imogen Locke Bhupinder Sharma Simon Doran Matthew Orton Catey Bunce Danielle Power Shahreen Ahmad Karen Chan Peng Ng Richard Toshner Binna Source Type: research

Validated machine learning tools to distinguish checkpoint inhibitor, radiotherapy, COVID-19 and other infective pneumonitis
CONCLUSION: Our results demonstrate the potential utility of such tools as a second or concurrent reader to support oncologists, radiologists, and chest physicians in cases of diagnostic uncertainty. Further research is required for patients with exposure to both ICI and thoracic radiotherapy.PMID:38582181 | DOI:10.1016/j.radonc.2024.110266 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 6, 2024 Category: Radiology Authors: Sumeet Hindocha Benjamin Hunter Kristofer Linton-Reid Thomas George Charlton Mitchell Chen Andrew Logan Merina Ahmed Imogen Locke Bhupinder Sharma Simon Doran Matthew Orton Catey Bunce Danielle Power Shahreen Ahmad Karen Chan Peng Ng Richard Toshner Binna Source Type: research

Photon vs proton hypofractionation in prostate Cancer: A systematic review and meta-analysis
CONCLUSION: The present study supports that PT is safe and effective for localized PCa treatment, however, more data from RCTs are needed to draw solid evidence in this setting and further effort must be made to identify the patient subgroups that could benefit the most from PT.PMID:38561122 | DOI:10.1016/j.radonc.2024.110264 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 1, 2024 Category: Radiology Authors: Giulia Corrao Giulia Marvaso Federico Mastroleo Annalisa Biffi Giacomo Pellegrini Samuele Minari Maria Giulia Vincini Mattia Zaffaroni Dario Zerini Stefania Volpe Simona Gaito Giovanni Carlo Mazzola Luca Bergamaschi Federica Cattani Giuseppe Petralia Genn Source Type: research

Photon vs proton hypofractionation in prostate Cancer: A systematic review and meta-analysis
CONCLUSION: The present study supports that PT is safe and effective for localized PCa treatment, however, more data from RCTs are needed to draw solid evidence in this setting and further effort must be made to identify the patient subgroups that could benefit the most from PT.PMID:38561122 | DOI:10.1016/j.radonc.2024.110264 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 1, 2024 Category: Radiology Authors: Giulia Corrao Giulia Marvaso Federico Mastroleo Annalisa Biffi Giacomo Pellegrini Samuele Minari Maria Giulia Vincini Mattia Zaffaroni Dario Zerini Stefania Volpe Simona Gaito Giovanni Carlo Mazzola Luca Bergamaschi Federica Cattani Giuseppe Petralia Genn Source Type: research

Photon vs proton hypofractionation in prostate Cancer: A systematic review and meta-analysis
CONCLUSION: The present study supports that PT is safe and effective for localized PCa treatment, however, more data from RCTs are needed to draw solid evidence in this setting and further effort must be made to identify the patient subgroups that could benefit the most from PT.PMID:38561122 | DOI:10.1016/j.radonc.2024.110264 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 1, 2024 Category: Radiology Authors: Giulia Corrao Giulia Marvaso Federico Mastroleo Annalisa Biffi Giacomo Pellegrini Samuele Minari Maria Giulia Vincini Mattia Zaffaroni Dario Zerini Stefania Volpe Simona Gaito Giovanni Carlo Mazzola Luca Bergamaschi Federica Cattani Giuseppe Petralia Genn Source Type: research

Photon vs proton hypofractionation in prostate Cancer: A systematic review and meta-analysis
CONCLUSION: The present study supports that PT is safe and effective for localized PCa treatment, however, more data from RCTs are needed to draw solid evidence in this setting and further effort must be made to identify the patient subgroups that could benefit the most from PT.PMID:38561122 | DOI:10.1016/j.radonc.2024.110264 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 1, 2024 Category: Radiology Authors: Giulia Corrao Giulia Marvaso Federico Mastroleo Annalisa Biffi Giacomo Pellegrini Samuele Minari Maria Giulia Vincini Mattia Zaffaroni Dario Zerini Stefania Volpe Simona Gaito Giovanni Carlo Mazzola Luca Bergamaschi Federica Cattani Giuseppe Petralia Genn Source Type: research

Long-term survival in patients with brain-only metastatic non-small cell lung cancer undergoing upfront intracranial stereotactic radiosurgery and definitive treatment to the thoracic primary site
CONCLUSION: Definitive treatment to the thoracic primary site in patients with brain-only metastatic NSCLC after intracranial radiosurgery was associated with slower progression of disease and improved survival.PMID:38556172 | DOI:10.1016/j.radonc.2024.110262 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 31, 2024 Category: Radiology Authors: K Salari J S Lee H Ye Z A Seymour K C Lee P Chinnaiyan I S Grills Source Type: research

Mri-guided dynamic risk assessment in cervical cancer based on tumor hypoxia at diagnosis and volume response at brachytherapy
CONCLUSION: The combination of pretreatment hypoxia and volume regression at brachytherapy improved patient risk classification. Integration of ADC with volume regression showed promise as a new tumor response parameter.PMID:38556173 | DOI:10.1016/j.radonc.2024.110263 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 31, 2024 Category: Radiology Authors: Kjersti Skipar Tord Hompland Kjersti V Lund Kristina Lindemann Taran P Hellebust Kjersti Bruheim Heidi Lyng Source Type: research

Long-term survival in patients with brain-only metastatic non-small cell lung cancer undergoing upfront intracranial stereotactic radiosurgery and definitive treatment to the thoracic primary site
CONCLUSION: Definitive treatment to the thoracic primary site in patients with brain-only metastatic NSCLC after intracranial radiosurgery was associated with slower progression of disease and improved survival.PMID:38556172 | DOI:10.1016/j.radonc.2024.110262 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 31, 2024 Category: Radiology Authors: K Salari J S Lee H Ye Z A Seymour K C Lee P Chinnaiyan I S Grills Source Type: research

Mri-guided dynamic risk assessment in cervical cancer based on tumor hypoxia at diagnosis and volume response at brachytherapy
CONCLUSION: The combination of pretreatment hypoxia and volume regression at brachytherapy improved patient risk classification. Integration of ADC with volume regression showed promise as a new tumor response parameter.PMID:38556173 | DOI:10.1016/j.radonc.2024.110263 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 31, 2024 Category: Radiology Authors: Kjersti Skipar Tord Hompland Kjersti V Lund Kristina Lindemann Taran P Hellebust Kjersti Bruheim Heidi Lyng Source Type: research

Testosterone recovery after androgen deprivation therapy in localised prostate cancer: Long-term data from two randomised trials
CONCLUSIONS: Testosterone recovery rate after ADT depends on several factors including hormonal duration, normal baseline T, age and medical comorbidities. A longer ADT duration is the most important variable affecting T recovery. The data from this report might be a valuable tool to help physicians and patients in evaluating risks and benefits of ADT.PMID:38552845 | DOI:10.1016/j.radonc.2024.110256 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 29, 2024 Category: Radiology Authors: Abdenour Nabid Nathalie Carrier Andr é-Guy Martin Eric Vigneault Jean-Paul Bahary Thu Van Nguyen Peter Vavassis Sylvie Vass Marc-Andr é Brassard Boris Bahoric Robert Archambault Fran çois Vincent Redouane Bettahar Marie Duclos Derek Wilke Luis Souhami Source Type: research

Testosterone recovery after androgen deprivation therapy in localised prostate cancer: Long-term data from two randomised trials
CONCLUSIONS: Testosterone recovery rate after ADT depends on several factors including hormonal duration, normal baseline T, age and medical comorbidities. A longer ADT duration is the most important variable affecting T recovery. The data from this report might be a valuable tool to help physicians and patients in evaluating risks and benefits of ADT.PMID:38552845 | DOI:10.1016/j.radonc.2024.110256 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 29, 2024 Category: Radiology Authors: Abdenour Nabid Nathalie Carrier Andr é-Guy Martin Eric Vigneault Jean-Paul Bahary Thu Van Nguyen Peter Vavassis Sylvie Vass Marc-Andr é Brassard Boris Bahoric Robert Archambault Fran çois Vincent Redouane Bettahar Marie Duclos Derek Wilke Luis Souhami Source Type: research