Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Neurological complications of modern radiotherapy for head and neck cancer
This article endeavors to provide a comprehensive review of the various neurological complications of modern radiotherapy for HNC, summarize the current incidence data, discuss methods to minimize their risks during radiotherapy planning, and highlight potential strategies for managing these debilitating toxicities.PMID:38438018 | DOI:10.1016/j.radonc.2024.110200 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 4, 2024 Category: Radiology Authors: James C H Chow Jason C S Ho Ka Man Cheung David Johnson Bonaventure Y M Ip Jonathan J Beitler Primo ž Strojan Antti A M äkitie Avraham Eisbruch Sweet Ping Ng Sandra Nuyts William M Mendenhall Silvia Babighian Alfio Ferlito Source Type: research

Four steps in the evolution of rectal cancer managements through 40 years of clinical practice: pioneering, standardization, challenges and personalization
CONCLUSIONS: The phased analysis underscores a 40-year trajectory in RC treatment, demonstrating a continuous cycle of improvement in patient care. Pioneering efforts established feasibility, while subsequent phases optimized techniques, addressed challenges, and prioritized personalized approaches. The study contributes valuable insights for advancing individualized and effective RC management strategies, emphasizing the significance of multidisciplinary collaboration and data-driven innovation. These data were presented at the Jens Overgaard Legacy Award Lecture at the ESTRO 2023 congress, Vienna 13 May 2023.PMID:3843801...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 4, 2024 Category: Radiology Authors: Vincenzo Valentini Sergio Alfieri Claudio Coco Domenico D'Ugo Antonio Crucitti Fabio Pacelli Roberto Persiani Luigi Sofo Aurelio Picciocchi Giovanni Battista Doglietto Brunella Barbaro Fabio Maria Vecchio Riccardo Ricci Andrea Damiani Maria Chiara Savino Source Type: research

Characterization of the signal transduction cascade for inflammatory gene expression in fibroblasts with ATM-ATR deficiencies after Ionizing radiation
CONCLUSION: Enhanced micronuclei formation upon ATM, ATR, or MRE11 deficiency activated the cGAS/STING, RIG-I-MDA-5-IRF7-IL6 pathway, resulting in its downstream interferon stimulated gene expression following exposure to IR. Our study provides comprehensive information regarding the status of inflammation-related gene expression under DSB repair deficiency after IR. The generated dataset may be useful in developing functional biomarkers to accurately identify patients sensitive to radiotherapy.PMID:38438016 | DOI:10.1016/j.radonc.2024.110198 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeu...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 4, 2024 Category: Radiology Authors: Shunji Haruna Ken Okuda Akiko Shibata Mayu Isono Kohei Tateno Hiro Sato Takahiro Oike Yuki Uchihara Yu Kato Atsushi Shibata Source Type: research

Less than whole uterus irradiation for patients with locally advanced cervical cancer
CONCLUSIONS: Including less than the whole uterus for definitive cervix cancer IMRT does not seem to compromise local control. Less than whole uterus irradiation could be considered for carefully selected cervix cancer patients to decrease bowel dose and possible treatment-related toxicity.PMID:38438017 | DOI:10.1016/j.radonc.2024.110199 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 4, 2024 Category: Radiology Authors: Caressa Hui Agnes Ewongwo Maria G Mendoza Margaret M Kozak Scott Jackson Jie Fu Elizabeth Kidd Source Type: research

Radiotherapy alone versus concurrent chemoradiotherapy in patients with stage II and T3N0 nasopharyngeal carcinoma with adverse features: A propensity score-matched cohort study
CONCLUSION: For patients with stage II and T3N0 NPC with adverse features treated using IMRT, no improvement in survival was gained by adding concurrent chemotherapy; however, the occurrence of acute toxicities increased significantly. For those combined with non-single adverse factors, the comprehensive treatment strategy needs further exploration.PMID:38432309 | DOI:10.1016/j.radonc.2024.110189 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 3, 2024 Category: Radiology Authors: Wei-Wei Zhang Jia-Yi Lin Gao-Yuan Wang Cheng-Long Huang Ling-Long Tang Yan-Ping Mao Guan-Qun Zhou Li-Zhi Liu Li Tian Ji-Bin Li Jun Ma Rui Guo Source Type: research

Long-term results of intraoperative multicatheter breast implant (IOMBI) for accelerated partial breast irradiation (APBI) on early breast cancer patients
CONCLUSION: IOMBI&PHDRBT program reports excellent long-term oncological outcomes, with a reduction from unnecessary irradiation exposure which translates into low long-term toxicity and good cosmesis outcomes, especially on well-selected APBI patients.PMID:38432310 | DOI:10.1016/j.radonc.2024.110193 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 3, 2024 Category: Radiology Authors: Marta Gimeno-Morales Rafael Mart ínez-Monge Adriana Martinez-Lage Paola Anna Jablonska Javier Blanco Fernando Mart ínez-Regueira Natalia Rodriguez-Spiteri Bego ña Olartecoechea Luis Ramos Luis Pina Insausti Arlette Elizalde Marta Abengozar Mauricio Cam Source Type: research

Assessment of bias in scoring of AI-based radiotherapy segmentation and planning studies using modified TRIPOD and PROBAST guidelines as an example
CONCLUSION: Our study showed low reliability scores with the adapted TRIPOD and PROBAST checklists. Although such checklists have shown great value during development and reporting, this raises concerns about the applicability of such checklists to objectively score scientific articles for AI applications. When developing or revising guidelines, it is essential to consider their applicability to score articles without introducing bias.PMID:38432311 | DOI:10.1016/j.radonc.2024.110196 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 3, 2024 Category: Radiology Authors: Coen Hurkmans Jean-Emmanuel Bibault Enrico Clementel Jennifer Dhont Wouter van Elmpt Georgios Kantidakis Nicolaus Andratschke Source Type: research

Impact of electronic patient-reported outcome measures on patients' perception of the physician - the randomized ePREFERENCE study
CONCLUSION: The ePREFERENCE trial shows that the implementation of ePROMs in clinic visits during radiotherapy treatment positively impacts the patients' perception of the physician's compassion. ePROMs can therefore not only be considered a useful tool to improve workflows but are also broadly accepted by patients.PMID:38428640 | DOI:10.1016/j.radonc.2024.110192 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 1, 2024 Category: Radiology Authors: C Gani P Bickenbach A Tenev M Niyazi T Festl-Wietek A Herrmann-Werner Source Type: research

Skin dose-volume predictors of moderate-severe late side effects after whole breast radiotherapy
CONCLUSIONS: The association between late reactions and skin DVH when delivering 40 Gy/15 fr was quantified, suggesting an independent role of V20 and V42. Few clinical factors heavily modulate the risk.PMID:38423138 | DOI:10.1016/j.radonc.2024.110183 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - February 29, 2024 Category: Radiology Authors: Alessandro Cicchetti Paola Mangili Andrei Fodor Maria Giulia Ubeira Gabellini Anna Chiara Chiara Deantoni Martina Mori Marcella Pasetti Gabriele Palazzo Tiziana Rancati Antonella Del Vecchio Nadia Gisella Di Muzio Claudio Fiorino Source Type: research

Letter to the editor regarding "External validation of a lung cancer-based prediction model for two-year mortality in esophageal cancer patient cohorts" by M. Berb ée et al
Radiother Oncol. 2024 Feb 28:110175. doi: 10.1016/j.radonc.2024.110175. Online ahead of print.NO ABSTRACTPMID:38417534 | DOI:10.1016/j.radonc.2024.110175 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - February 28, 2024 Category: Radiology Authors: P Populaire G Defraene K Haustermans Source Type: research