Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Essential requirements for reporting radiation therapy in breast cancer clinical trials: an international multi-disciplinary consensus endorsed by the European SocieTy for Radiotherapy and Oncology (ESTRO)
This article is grounded in a consensus recommendation endorsed by ESTRO, formulated by international breast cancer experts. The consensus was reached through a modified Delphi process and was presented at an international meeting convened in Florence, Italy, in June 2023. These recommendations are regarded as both optimal and essential standards, with the latter aiming to define the minimum requirements. A template for a case report form (CRF) has been devised, which can be utilised by all clinical breast cancer trials involving RT. Optimal requirements include adherence to predefined RT planning protocols and centralised...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 20, 2023 Category: Radiology Authors: Orit Kaidar-Person Icro Meattini Liesbeth J Boersma Carlotta Becherini Javier Cortes Giuseppe Curigliano Evandro de Azambuja Nadia Harbeck Hope S Rugo Lucia Del Mastro Alessandra Gennari Clare M Isacke Maja Vestm ø Maraldo Elisabetta Marangoni Gustavo Na Source Type: research

In Reply To: Comment on: Improved Local Control following Dose-Escalated Stereotactic Ablative Radiation Therapy (SABR) for Metastatic Sarcomas: An International Multi-Institutional Experience
Radiother Oncol. 2023 Dec 18:110058. doi: 10.1016/j.radonc.2023.110058. Online ahead of print.NO ABSTRACTPMID:38122853 | DOI:10.1016/j.radonc.2023.110058 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 20, 2023 Category: Radiology Authors: Raj Singh Source Type: research

The value of subcutaneous xenografts for individualised radiotherapy in HNSCC: robust gene signature correlates with radiotherapy outcome in patients and xenografts
CONCLUSION: Genetic prognosticators of outcome for patients after PORT-C and subcutaneous xenografts after primary clinically relevant irradiation show similarity. The identified robust 2-gene signature may help to guide patient stratification, after prospective validation. Thus, xenografts remain a valuable resource for translational research towards the development of individualized radiotherapy.PMID:38109944 | DOI:10.1016/j.radonc.2023.110055 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 18, 2023 Category: Radiology Authors: Annett Linge Shivaprasad Patil Marianne Grosser Fabian Lohaus Kristin Gurtner Max Kemper Volker Gudziol Dominik Haim Alexander Nowak Inge Tinhofer Daniel Zips Maja Guberina Martin Stuschke Panagiotis Balermpas Claus R ödel Henning Sch äfer Anca-Ligia Gr Source Type: research

Which tumour factors preclude organ preservation in patients with rectal cancer?
CONCLUSION: Sustained cCR after routine preoperative radio(chemo)therapy is unlikely in patients with (near-)circular tumour or EMVI, whereas patients with cT3cdT4, cN2, mesorectal nodes >8 mm, clinically positive lateral nodes and MRF+ should not be denied w&w.PMID:38104780 | DOI:10.1016/j.radonc.2023.110054 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 17, 2023 Category: Radiology Authors: Anna Ho łdakowska Kamila Kurkowska Lucyna Pietrzak Wojciech Michalski Andrzej Rutkowski Tomasz Olesi ński Anna Cencelewicz Martin Rydzi ński Joanna Socha Krzysztof Bujko Source Type: research

Uncertainty-aware MR-based CT synthesis for robust proton therapy planning of brain tumour
CONCLUSION: The enhanced framework incorporates 3D uncertainty prediction and generates high-quality sCTs from MR images. The framework also facilitates conditioned robust optimisation, bolstering proton plan robustness against network prediction errors. The innovative feature of uncertainty visualisation and robust analyses contribute to evaluating sCT clinical utility for individual patients.PMID:38104781 | DOI:10.1016/j.radonc.2023.110056 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 17, 2023 Category: Radiology Authors: Xia Li Renato Bellotti Gabriel Meier Barbara Bachtiary Damien Weber Antony Lomax Joachim Buhmann Ye Zhang Source Type: research

Predictive factors for severe radiation-induced lung injury in patients with lung cancer and coexisting interstitial lung disease
CONCLUSION: Pretreatment blood NLR, ANC, and ILD severity were associated with severe RILI. Overall survival was dismal for patients with severe RILI.PMID:38104782 | DOI:10.1016/j.radonc.2023.110053 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 17, 2023 Category: Radiology Authors: Shin-Hyung Park Jae Kwang Lim Conceptualizatin Min Kyu Kang Jongmoo Park Chae Moon Hong Chang Ho Kim Seung Ick Cha Jaehee Lee Seoung-Jun Lee Jae-Chul Kim Source Type: research

Clinical outcomes of stereotactic body radiation therapy for malignant pleural mesothelioma
CONCLUSIONS: Our single-institutional experience on patients with MPM suggests that SBRT is safe with a low toxicity profile and potentially achieve good local control.PMID:38104783 | DOI:10.1016/j.radonc.2023.110057 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 17, 2023 Category: Radiology Authors: Jacob Y Shin Michael Offin Charles B Simone Ii Zhigang Zhang Annemarie F Shepherd Abraham J Wu Narek Shaverdian Daphna Y Gelblum Daniel R Gomez Jennifer L Sauter Michelle S Ginsberg Prasad S Adusumilli Valerie W Rusch Marjorie G Zauderer Andreas Rimner Source Type: research

Radiologic extranodal extension for nodal staging in nasopharyngeal carcinoma
CONCLUSION: Results from two centre cohorts confirmed that the radiological advanced ENE should be considered as a criterion for stage N3 disease in NPC.PMID:38101457 | DOI:10.1016/j.radonc.2023.110050 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 15, 2023 Category: Radiology Authors: Qi Yong H Ai Ann D King Hui Yuan Varut Vardhanabhuti Frankie K F Mo Kuo Feng Hung Edwin P Hui Dora Lai-Wan Kwong Victor Ho-Fun Lee Brigette B Y Ma Source Type: research

Deep learning MRI-only synthetic-CT generation for pelvis, brain and head and neck cancers
CONCLUSION: Generated sCTs had excellent dosimetric accuracy for all sites and sequences. The cycle-GAN model, available on the research version of a commercial treatment planning system, is a feasible method for sCT generation with high clinical utility due to its ability to use variable input data from multiple scanners and sequences.PMID:38096921 | DOI:10.1016/j.radonc.2023.110052 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 14, 2023 Category: Radiology Authors: David Bird Richard Speight Sebastian Andersson Jenny Wingqvist Bashar Al-Qaisieh Source Type: research

Radio-chemotherapy of glioblastoma cells promotes phagocytosis by macrophages in vitro
CONCLUSIONS: and Perspectives We showed that macrophage phagocytic activity increased when exposed to supernatant from GBM cells treated by radio-chemotherapy. However, as efferocytosis-associated receptors were up-regulated, this effect could be deleterious for the anti-GBM immune response. We speculate that by inducing GBM cell apoptosis in parallel to an increase in efferocytosis receptor expression, the impact of radio-chemotherapy on phagocytic activity could promote anti-inflammatory and pro-tumoral TAM functions.PMID:38072365 | DOI:10.1016/j.radonc.2023.110049 (Source: Radiotherapy and Oncology : journal of the Euro...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 10, 2023 Category: Radiology Authors: Marc Lecoultre Sylvie Chliate Felipe I Espinoza Stoyan Tankov Val érie Dutoit Paul R Walker Source Type: research