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Long-term survival outcomes and quality of life of image-guided proton therapy for operable stage I non-small cell lung cancer: A phase 2 study
CONCLUSION: Our findings suggest that IGPT provides effective disease control and survival in operable stage I NSCLC, particularly for peripheral lesions. Moreover, toxicity associated with IGPT was minimal, and patients reported favorable QOL.PMID:38614284 | DOI:10.1016/j.radonc.2024.110276 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 13, 2024 Category: Radiology Authors: Koichiro Nakajima Masanosuke Oguri Hiromitsu Iwata Yukiko Hattori Shingo Hashimoto Kento Nomura Kensuke Hayashi Toshiyuki Toshito Kenji Akita Fumiya Baba Hiroyuki Ogino Akio Hiwatashi Source Type: research

Comparing the effects of irradiation with protons or photons on neonatal mouse brain: Apoptosis, oncogenesis and hippocampal alterations
CONCLUSION: In-vivo experiments with radiosensitive mouse models improve our mechanistic understanding of the dependence of brain damage on radiation quality, thus having important implications in translational research.PMID:38614282 | DOI:10.1016/j.radonc.2024.110267 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 13, 2024 Category: Radiology Authors: Daniela Giovannini Francesca Antonelli Arianna Casciati Cinzia De Angelis Maria Denise Astorino Giulia Bazzano Emiliano Fratini Alessandro Ampollini Monia Vadrucci Evaristo Cisbani Paolo Nenzi Luigi Picardi Anna Saran Carmela Marino Mariateresa Mancuso Co Source Type: research

Postoperative radiotherapy results in 192 epithelial thymic tumours patients with 10  years of follow-up
CONCLUSION: Approximately one-third of the TET in our study experienced a LRR, mainly to the pleura, and 8% in total were in-field. The place of radiotherapy should be better defined in higher risk thymoma patients within prospective randomized studies.PMID:38614283 | DOI:10.1016/j.radonc.2024.110272 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 13, 2024 Category: Radiology Authors: Hugo Lopez Angela Botticella Farid Belkhir Benjamin Besse Elie Fadel Olaf Mercier Antonin Levy C écile Le Péchoux Source Type: research

Long-term survival outcomes and quality of life of image-guided proton therapy for operable stage I non-small cell lung cancer: A phase 2 study
CONCLUSION: Our findings suggest that IGPT provides effective disease control and survival in operable stage I NSCLC, particularly for peripheral lesions. Moreover, toxicity associated with IGPT was minimal, and patients reported favorable QOL.PMID:38614284 | DOI:10.1016/j.radonc.2024.110276 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 13, 2024 Category: Radiology Authors: Koichiro Nakajima Masanosuke Oguri Hiromitsu Iwata Yukiko Hattori Shingo Hashimoto Kento Nomura Kensuke Hayashi Toshiyuki Toshito Kenji Akita Fumiya Baba Hiroyuki Ogino Akio Hiwatashi Source Type: research

Re-irradiation for recurrent intracranial meningiomas: Analysis of clinical outcomes and prognostic factors
CONCLUSIONS: In patients with recurrent meningiomas, reirradiation is a feasible treatment option associated with acceptable toxicity profile. Prognostic factors in the decision-making process have been identified and should be incorporated in daily practice.PMID:38588920 | DOI:10.1016/j.radonc.2024.110271 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 8, 2024 Category: Radiology Authors: Isacco Desideri Ilaria Morelli Marco Banini Daniela Greto Luca Visani Filippo Nozzoli Saverio Caini Alessandro Della Puppa Lorenzo Livi Zeno Perini Emanuele Zivelonghi Giorgia Bulgarelli Valentina Pinzi Pierina Navarria Elena Clerici Marta Scorsetti Anna Source Type: research

Brachytherapy for rhabdomyosarcoma: Survey of international clinical practice and development of guidelines
CONCLUSIONS: Consensus guidelines for the use of brachytherapy in pediatric rhabdomyosarcoma have been developed through multicenter collaboration establishing the basis for future work. These have been adopted for the open EpSSG overarching study for children and adults with Frontline and Relapsed RhabdoMyoSarcoma (FaR-RMS).PMID:38588921 | DOI:10.1016/j.radonc.2024.110273 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 8, 2024 Category: Radiology Authors: Raquel D ávila Fajardo Giovanni Scarzello Mark N Gaze Tom Boterberg Alison Cameron Joerg Fuchs Florent Gu érin Peter Hoskin Matthew J Krasin Petra Kroon Henriette Magelssen Claes Mercke Johannes H M Merks Frank Paulsen Pascal Pommier Monica Ramos Helen Source Type: research

Re-irradiation for recurrent intracranial meningiomas: Analysis of clinical outcomes and prognostic factors
CONCLUSIONS: In patients with recurrent meningiomas, reirradiation is a feasible treatment option associated with acceptable toxicity profile. Prognostic factors in the decision-making process have been identified and should be incorporated in daily practice.PMID:38588920 | DOI:10.1016/j.radonc.2024.110271 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 8, 2024 Category: Radiology Authors: Isacco Desideri Ilaria Morelli Marco Banini Daniela Greto Luca Visani Filippo Nozzoli Saverio Caini Alessandro Della Puppa Lorenzo Livi Zeno Perini Emanuele Zivelonghi Giorgia Bulgarelli Valentina Pinzi Pierina Navarria Elena Clerici Marta Scorsetti Anna Source Type: research

Brachytherapy for rhabdomyosarcoma: Survey of international clinical practice and development of guidelines
CONCLUSIONS: Consensus guidelines for the use of brachytherapy in pediatric rhabdomyosarcoma have been developed through multicenter collaboration establishing the basis for future work. These have been adopted for the open EpSSG overarching study for children and adults with Frontline and Relapsed RhabdoMyoSarcoma (FaR-RMS).PMID:38588921 | DOI:10.1016/j.radonc.2024.110273 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 8, 2024 Category: Radiology Authors: Raquel D ávila Fajardo Giovanni Scarzello Mark N Gaze Tom Boterberg Alison Cameron Joerg Fuchs Florent Gu érin Peter Hoskin Matthew J Krasin Petra Kroon Henriette Magelssen Claes Mercke Johannes H M Merks Frank Paulsen Pascal Pommier Monica Ramos Helen Source Type: research

Re-irradiation for recurrent intracranial meningiomas: Analysis of clinical outcomes and prognostic factors
CONCLUSIONS: In patients with recurrent meningiomas, reirradiation is a feasible treatment option associated with acceptable toxicity profile. Prognostic factors in the decision-making process have been identified and should be incorporated in daily practice.PMID:38588920 | DOI:10.1016/j.radonc.2024.110271 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 8, 2024 Category: Radiology Authors: Isacco Desideri Ilaria Morelli Marco Banini Daniela Greto Luca Visani Filippo Nozzoli Saverio Caini Alessandro Della Puppa Lorenzo Livi Zeno Perini Emanuele Zivelonghi Giorgia Bulgarelli Valentina Pinzi Pierina Navarria Elena Clerici Marta Scorsetti Anna Source Type: research

Brachytherapy for rhabdomyosarcoma: Survey of international clinical practice and development of guidelines
CONCLUSIONS: Consensus guidelines for the use of brachytherapy in pediatric rhabdomyosarcoma have been developed through multicenter collaboration establishing the basis for future work. These have been adopted for the open EpSSG overarching study for children and adults with Frontline and Relapsed RhabdoMyoSarcoma (FaR-RMS).PMID:38588921 | DOI:10.1016/j.radonc.2024.110273 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 8, 2024 Category: Radiology Authors: Raquel D ávila Fajardo Giovanni Scarzello Mark N Gaze Tom Boterberg Alison Cameron Joerg Fuchs Florent Gu érin Peter Hoskin Matthew J Krasin Petra Kroon Henriette Magelssen Claes Mercke Johannes H M Merks Frank Paulsen Pascal Pommier Monica Ramos Helen Source Type: research

Re-irradiation for recurrent intracranial meningiomas: Analysis of clinical outcomes and prognostic factors
CONCLUSIONS: In patients with recurrent meningiomas, reirradiation is a feasible treatment option associated with acceptable toxicity profile. Prognostic factors in the decision-making process have been identified and should be incorporated in daily practice.PMID:38588920 | DOI:10.1016/j.radonc.2024.110271 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 8, 2024 Category: Radiology Authors: Isacco Desideri Ilaria Morelli Marco Banini Daniela Greto Luca Visani Filippo Nozzoli Saverio Caini Alessandro Della Puppa Lorenzo Livi Zeno Perini Emanuele Zivelonghi Giorgia Bulgarelli Valentina Pinzi Pierina Navarria Elena Clerici Marta Scorsetti Anna Source Type: research

Brachytherapy for rhabdomyosarcoma: Survey of international clinical practice and development of guidelines
CONCLUSIONS: Consensus guidelines for the use of brachytherapy in pediatric rhabdomyosarcoma have been developed through multicenter collaboration establishing the basis for future work. These have been adopted for the open EpSSG overarching study for children and adults with Frontline and Relapsed RhabdoMyoSarcoma (FaR-RMS).PMID:38588921 | DOI:10.1016/j.radonc.2024.110273 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 8, 2024 Category: Radiology Authors: Raquel D ávila Fajardo Giovanni Scarzello Mark N Gaze Tom Boterberg Alison Cameron Joerg Fuchs Florent Gu érin Peter Hoskin Matthew J Krasin Petra Kroon Henriette Magelssen Claes Mercke Johannes H M Merks Frank Paulsen Pascal Pommier Monica Ramos Helen Source Type: research

Reirradiation for recurrent gynecologic cancer using high-dose-rate brachytherapy in Japan: A multicenter survey on practice patterns and outcomes
CONCLUSION: Reirradiation with HDR brachytherapy for recurrent gynecologic cancer is effective, especially in cases with a long interval before reirradiation.PMID:38583719 | DOI:10.1016/j.radonc.2024.110269 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 7, 2024 Category: Radiology Authors: Fumiaki Isohashi Ken Yoshida Naoya Murakami Koji Masui Shunichi Ishihara Yu Ohkubo Yuko Kaneyasu Rumiko Kinoshita Tadayuki Kotsuma Yuji Takaoka Eiichi Tanaka Ayaka Nagao Kazuhiko Ogawa Hideya Yamazaki Source Type: research

Long-term efficacy analysis of radiotherapy and local management of metastases in patients with newly diagnosed oligometastatic nasopharyngeal carcinoma: A prospective, single-arm, single-center clinical study
CONCLUSION: Patients with newly diagnosed oligometastatic NPC can achieve long-term survival after receiving radical radiotherapy to the primary site and local treatment for metastases.PMID:38583720 | DOI:10.1016/j.radonc.2024.110265 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 7, 2024 Category: Radiology Authors: Huang Shuang Jiang Feng Cao Caineng Jin Qifeng Jin Ting Hua Yonghong Chen Xiaozhong Source Type: research

Comprehensive radiotherapy for pediatric Ewing Sarcoma: Outcomes of a prospective proton study
CONCLUSION: In conclusion, LC for pediatric patients with EWS treated with PRT was comparable to that of historical patients who received photon-RT. Tumor size ≥ 8 cm predicted increased risk of local failure. Patients with metastatic disease, including non-pulmonary only metastases, received radiation therapy to all metastatic sites and had favorable survival outcomes.PMID:38583721 | DOI:10.1016/j.radonc.2024.110270 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 7, 2024 Category: Radiology Authors: Julianna K Bronk Mary Frances McAleer Susan L McGovern Yasmin Lassen-Ramshad Akmal Safwat Najat C Daw Nino Rainusso Anita Mahajan David R Grosshans Arnold C Paulino Source Type: research