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The long-term impact of irradiation on functional connectivity in brain circuits involved in memory processes after pediatric posterior fossa tumor
CONCLUSION: The results of this study highlight that irradiation has a long-term impact on brain connectivity in brain circuits involved in memory after pediatric PFT with a specific radiation-dose effect in supratentorial structures.PMID:38145791 | DOI:10.1016/j.radonc.2023.110073 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 25, 2023 Category: Radiology Authors: Elo ïse Baudou Patrice Peran Fatima Tensaouti Germain Arribarat J érémie Pariente Nicolas Courbieres Lisa Pollidoro Anne-Isabelle Bertozzi Marion Gambart Annick Sevely Margaux Roques Anne Ducassou J érémy Danna Jessica Tallet Christelle Dufour Yves C Source Type: research

The long-term impact of irradiation on functional connectivity in brain circuits involved in memory processes after pediatric posterior fossa tumor
CONCLUSION: The results of this study highlight that irradiation has a long-term impact on brain connectivity in brain circuits involved in memory after pediatric PFT with a specific radiation-dose effect in supratentorial structures.PMID:38145791 | DOI:10.1016/j.radonc.2023.110073 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 25, 2023 Category: Radiology Authors: Elo ïse Baudou Patrice Peran Fatima Tensaouti Germain Arribarat J érémie Pariente Nicolas Courbieres Lisa Pollidoro Anne-Isabelle Bertozzi Marion Gambart Annick Sevely Margaux Roques Anne Ducassou J érémy Danna Jessica Tallet Christelle Dufour Yves C Source Type: research

The long-term impact of irradiation on functional connectivity in brain circuits involved in memory processes after pediatric posterior fossa tumor
CONCLUSION: The results of this study highlight that irradiation has a long-term impact on brain connectivity in brain circuits involved in memory after pediatric PFT with a specific radiation-dose effect in supratentorial structures.PMID:38145791 | DOI:10.1016/j.radonc.2023.110073 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 25, 2023 Category: Radiology Authors: Elo ïse Baudou Patrice Peran Fatima Tensaouti Germain Arribarat J érémie Pariente Nicolas Courbieres Lisa Pollidoro Anne-Isabelle Bertozzi Marion Gambart Annick Sevely Margaux Roques Anne Ducassou J érémy Danna Jessica Tallet Christelle Dufour Yves C Source Type: research

Machine-learning prediction of treatment response to stereotactic body radiation therapy in oligometastatic gynecological cancer: a multi-institutional study
CONCLUSION: ML models enable a reliable prediction of the treatment response of oligometastatic lesions receiving SBRT. This approach may assist radiation oncologists to tailor more individualized treatment plans for oligometastatic patients.PMID:38142932 | DOI:10.1016/j.radonc.2023.110072 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 24, 2023 Category: Radiology Authors: Savino Cilla Maura Campitelli Maria Antonietta Gambacorta Raffaella Michela Rinaldi Francesco Deodato Donato Pezzulla Carmela Romano Andrei Fodor Concetta Laliscia Fabio Trippa Vitaliana De Sanctis Edy Ippolito Martina Ferioli Francesca Titone Donatella R Source Type: research

Choosing the right questions - a systematic review of patient reported outcome measures used in radiotherapy and proton beam therapy
Radiother Oncol. 2023 Dec 22:110071. doi: 10.1016/j.radonc.2023.110071. Online ahead of print.ABSTRACTThe implementation of PROMs into clinical practice has been shown to improve quality of care. This systematic review aims to identify which PROMs are suitable for implementation within routine clinical practice in a radiotherapy or PBT service.The bibliographic databases MEDLINE, EMBASE and EMCARE were searched. Articles published between 1st January 2008 to 1st June 2023, that reported PROMs being utilised as an outcome measure were included. Inclusion criteria also included being written in English, involving human patie...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 24, 2023 Category: Radiology Authors: Danielle Fairweather Rachel Taylor Rita Sim ões Source Type: research

Statin Use Reduces Radiation-Induced Stroke Risk in Advanced Nasopharyngeal Carcinoma Patients
CONCLUSIONS: Our study provides evidence supporting the beneficial effects of statin use during the CCRT period in reducing radiation-induced stroke risk among patients with advanced NPC undergoing definitive CCRT. Notably, pravastatin and atorvastatin demonstrated significant reductions in stroke occurrence. Furthermore, the findings suggest a dose-response relationship, where higher cumulative doses and greater daily dose intensity of statin use were associated with a lower risk of stroke.PMID:38142934 | DOI:10.1016/j.radonc.2023.110067 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic ...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 24, 2023 Category: Radiology Authors: Chuan-Yi Lin Chia-Lun Chang Kuan-Chou Lin Wan-Ming Chen Ben-Chang Shia Po-Hsiu Kuo Szu-Yuan Wu Source Type: research

Volumetric Brain Assessment of Long-Term Head and Neck Cancer Survivors
CONCLUSIONS: Reductions in GM were observed within this cohort of primarily non-nasopharyngeal HNC survivors as compared to a control sample. GM volumes were associated with performance in multiple cognitive domains. Results of this exploratory study support the need for investigation of anatomic brain changes as an important translational corollary to cognitive problems among HNC survivors.PMID:38142935 | DOI:10.1016/j.radonc.2023.110068 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 24, 2023 Category: Radiology Authors: Donna L Murdaugh Desmin Milner Carlos E Cardenas Katherine A Heinzman Courtney A Cooper Jazmyne N Tabb Smita Bhatia Andrew M McDonald Source Type: research

Large Institutional Experience of Early Outcomes and Dosimetric Findings with Postoperative Stereotactic Partial Breast Irradiation in Breast Cancer
CONCLUSION: In this large cohort, S-PBI demonstrated favorable dosimetric and toxicity profiles. Considering the reduced radiation exposure to surrounding tissues, external beam PBI with advanced techniques should at least be considered over traditional WBI-based approaches for PBI candidates.PMID:38142936 | DOI:10.1016/j.radonc.2023.110066 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 24, 2023 Category: Radiology Authors: Jee Suk Chang Jeongshim Lee Frank A Vicini Jin Sung Kim Jihun Kim Seo Hee Choi Ik Jae Lee Yong Bae Kim Source Type: research

Machine-learning prediction of treatment response to stereotactic body radiation therapy in oligometastatic gynecological cancer: a multi-institutional study
CONCLUSION: ML models enable a reliable prediction of the treatment response of oligometastatic lesions receiving SBRT. This approach may assist radiation oncologists to tailor more individualized treatment plans for oligometastatic patients.PMID:38142932 | DOI:10.1016/j.radonc.2023.110072 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 24, 2023 Category: Radiology Authors: Savino Cilla Maura Campitelli Maria Antonietta Gambacorta Raffaella Michela Rinaldi Francesco Deodato Donato Pezzulla Carmela Romano Andrei Fodor Concetta Laliscia Fabio Trippa Vitaliana De Sanctis Edy Ippolito Martina Ferioli Francesca Titone Donatella R Source Type: research

Choosing the right questions - a systematic review of patient reported outcome measures used in radiotherapy and proton beam therapy
Radiother Oncol. 2023 Dec 22:110071. doi: 10.1016/j.radonc.2023.110071. Online ahead of print.ABSTRACTThe implementation of PROMs into clinical practice has been shown to improve quality of care. This systematic review aims to identify which PROMs are suitable for implementation within routine clinical practice in a radiotherapy or PBT service.The bibliographic databases MEDLINE, EMBASE and EMCARE were searched. Articles published between 1st January 2008 to 1st June 2023, that reported PROMs being utilised as an outcome measure were included. Inclusion criteria also included being written in English, involving human patie...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 24, 2023 Category: Radiology Authors: Danielle Fairweather Rachel Taylor Rita Sim ões Source Type: research

Statin Use Reduces Radiation-Induced Stroke Risk in Advanced Nasopharyngeal Carcinoma Patients
CONCLUSIONS: Our study provides evidence supporting the beneficial effects of statin use during the CCRT period in reducing radiation-induced stroke risk among patients with advanced NPC undergoing definitive CCRT. Notably, pravastatin and atorvastatin demonstrated significant reductions in stroke occurrence. Furthermore, the findings suggest a dose-response relationship, where higher cumulative doses and greater daily dose intensity of statin use were associated with a lower risk of stroke.PMID:38142934 | DOI:10.1016/j.radonc.2023.110067 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic ...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 24, 2023 Category: Radiology Authors: Chuan-Yi Lin Chia-Lun Chang Kuan-Chou Lin Wan-Ming Chen Ben-Chang Shia Po-Hsiu Kuo Szu-Yuan Wu Source Type: research

Volumetric Brain Assessment of Long-Term Head and Neck Cancer Survivors
CONCLUSIONS: Reductions in GM were observed within this cohort of primarily non-nasopharyngeal HNC survivors as compared to a control sample. GM volumes were associated with performance in multiple cognitive domains. Results of this exploratory study support the need for investigation of anatomic brain changes as an important translational corollary to cognitive problems among HNC survivors.PMID:38142935 | DOI:10.1016/j.radonc.2023.110068 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 24, 2023 Category: Radiology Authors: Donna L Murdaugh Desmin Milner Carlos E Cardenas Katherine A Heinzman Courtney A Cooper Jazmyne N Tabb Smita Bhatia Andrew M McDonald Source Type: research

Large Institutional Experience of Early Outcomes and Dosimetric Findings with Postoperative Stereotactic Partial Breast Irradiation in Breast Cancer
CONCLUSION: In this large cohort, S-PBI demonstrated favorable dosimetric and toxicity profiles. Considering the reduced radiation exposure to surrounding tissues, external beam PBI with advanced techniques should at least be considered over traditional WBI-based approaches for PBI candidates.PMID:38142936 | DOI:10.1016/j.radonc.2023.110066 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 24, 2023 Category: Radiology Authors: Jee Suk Chang Jeongshim Lee Frank A Vicini Jin Sung Kim Jihun Kim Seo Hee Choi Ik Jae Lee Yong Bae Kim Source Type: research

Quality assurance of radiation therapy after breast-conserving surgery among patients in the BOOG 2013-08 trial
Radiother Oncol. 2023 Dec 21:110069. doi: 10.1016/j.radonc.2023.110069. Online ahead of print.NO ABSTRACTPMID:38141879 | DOI:10.1016/j.radonc.2023.110069 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 23, 2023 Category: Radiology Authors: V M Wintraecken L J Boersma L M van Roozendaal J de Vries S M J van Kuijk M L G Vane T van Dalen J A van der Hage L J A Strobbe S C Linn M B I Lobbes P M P Poortmans V C G Tjan-Heijnen K K B T van de Vijver A H Westenberg J H W de Wilt M L Smidt J M Simon Source Type: research

Phase I dose-escalation study of nab-paclitaxel combined with cisplatin and capecitabin as induction chemotherapy followed by concurrent chemoradiotherapy in patients with nasopharyngeal carcinoma
CONCLUSION: The RP2D is nab-paclitaxel 200 mg/m2 on day 1, combined with cisplatin 75 mg/mg2 on day 1 and capecitabin1000 mg/m2 on days 1-14, twice a day, every 3 weeks, for three cycles as an IC regimen prior to CCRT.TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT04850235.PMID:38135184 | DOI:10.1016/j.radonc.2023.110051 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 22, 2023 Category: Radiology Authors: None Yu-Chen Mei-Juan Luo Rong-Ping Liu Jing Jin Sheng-Wen Deng Lin-Quan Tang Xiao-Yun Li Li-Ting Liu Dong-Hua Luo Rui Sun Sai-Lan Liu Ji-Bin Li Qing Liu Pan Wang Qiu-Yan Chen Hai-Qiang Mai Shan-Shan Guo Source Type: research