Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Balancing robustness and adaptation rate for proton therapy of lung cancer patients
CONCLUSION: The lowered risk of post treatment toxicities at lower robustness levels is clinically relevant but comes at the expense of more treatment adaptations, particularly in cases where meeting our clinical goals is not compromised by having a dose that is more conformal to the target. The trade-off between workload and reduced NTCP needs to be individually assessed.PMID:38643807 | DOI:10.1016/j.radonc.2024.110290 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 21, 2024 Category: Radiology Authors: Vlad Badiu Vicki Trier Taasti Gilles Defraene Wouter van Elmpt Edmond Sterpin Source Type: research

Assessing radiation-induced carotid artery injury using ultrasound in patients with head and neck cancer
CONCLUSION: RT significantly increased CCA IMT, and the growth was related to the radiation dose. The number and volume of the CCA plaques also increased after RT.PMID:38641258 | DOI:10.1016/j.radonc.2024.110285 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 19, 2024 Category: Radiology Authors: Zhuangzhuang Zheng Yingying Shen Jing Su Xiaorui Ji Qiang Zhang Qin Zhao Xin Jiang Source Type: research

Risk factors associated with the development of osteoradionecrosis (ORN) in Head and Neck cancer patients in Ireland: A 10-year retrospective review
CONCLUSION: This is the first retrospective study of ORN in HNC patients in Ireland over 10-year period. ORN incidence was extremely low (4.4%). As patients reported high smoking/alcohol use and poor dental attendance pre-diagnosis, this suggests intensive dental intervention pre/post-diagnosis contributed to low ORN rates. Mandibular surgery pre-RT increased risk of developing ORN at the surgical site. Therefore, we recommend future treatment planning should contour the surgical site, designating it an organ at risk (OAR), assigning a dose constraint, where oncologically possible, with emphasis on reducing the hot-spot to...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 19, 2024 Category: Radiology Authors: Kathleen T Fitzgerald Ciara Lyons Andrew England Mark F McEntee Annemarie Devine Theresa O'Donovan Eleanor O'Sullivan Source Type: research

Could a low-dose definitive radiation therapy be the optimal treatment for choroidal hemangioma?
CONCLUSION: Low-dose IMRT/VMAT could effectively induce involution of the CH, with reduction of subretinal fluid and relief of damage to the neurosensory retina, which is an effective treatment mode for CH.PMID:38641260 | DOI:10.1016/j.radonc.2024.110282 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 19, 2024 Category: Radiology Authors: Li Wang Tianci Tang Jie Wang Tong Lin Yi Li Xinmao Song Source Type: research

Predictive factors for radiation-induced pituitary damage in pediatric patients with brain tumors
CONCLUSION: Cranial irradiation in pediatric patients is associated with impairment of the physiologic increase in pituitary size; in turn, decreased pituitary height is associated with endocrine dysfunction. We suggest that pituitary gland should be evaluated on surveillance imaging of pediatric brain tumor survivors, and if small for age, clinical endocrine evaluation should be pursued.PMID:38641261 | DOI:10.1016/j.radonc.2024.110268 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 19, 2024 Category: Radiology Authors: Larisa Gorenstein Shai Shrot Michal Ben-Ami Eve Stern Michal Yalon Chen Hoffmann Shani Caspi Michal Lurye Amos Toren Gadi Abebe-Campino Dalit Modan-Moses Source Type: research

European Society of Radiotherapy and oncology (ESTRO) strategy 2024-2026: Growth and diversification in a rapidly changing world
Radiother Oncol. 2024 Apr 17:110283. doi: 10.1016/j.radonc.2024.110283. Online ahead of print.ABSTRACTIn 2019, the European Society of Radiotherapy and Oncology (ESTRO) published its 2030 Vision "Radiation Oncology, Optimal Health, For All, Together". However, in 2020, the global pandemic, coinciding with the Society's 40th anniversary, had long-term consequences on global behaviours and on the financial environment for scientific associations worldwide. In 2022, ESTRO conducted a survey among its members, revealing their strong appreciation for networking opportunities and the creation of high-quality interdisciplinary sc...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 19, 2024 Category: Radiology Authors: A M Kirby M Guckenberger B J Slotman C H Clark J G Eriksen U van der Heide S De Ioanna C Gasparotto A J Cortese ESTRO Board of Directors Source Type: research

A multicentric randomized controlled phase III trial of adaptive and 18F-FDG-PET-guided dose-redistribution in locally advanced head and neck squamous cell carcinoma (ARTFORCE)
CONCLUSION: Adaptive and dose redistributed radiotherapy enabled dose-escalation with similar toxicity rates compared to conventional radiotherapy. While FDG-PET-guided dose-escalation did overall not lead to significant tumor control or survival improvements, post-hoc results showed improved locoregional control for patients with N0-1 disease or oropharyngeal cancer treated with rRT.PMID:38636708 | DOI:10.1016/j.radonc.2024.110281 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 18, 2024 Category: Radiology Authors: Anna Liza M P de Leeuw Jordi Giralt Yungan Tao Sergi Benavente Thanh-V ân France Nguyen Frank J P Hoebers Ann Hoeben Chris H J Terhaard Lip Wai Lee Signe Friesland Roel J H M Steenbakkers Lisa Tans Jolien Heukelom Mutamba T Kayembe Simon R van Kranen Har Source Type: research

Using the genomic adjusted radiation dose (GARD) to personalize the radiation dose in nasopharyngeal cancer
CONCLUSION: GARD is independently associated with locoregional control in radiotherapy-treated NPC patients from a Phase 3 clinical trial. GARD may be a potential framework to personalize radiotherapy dose for NPC patients.PMID:38636709 | DOI:10.1016/j.radonc.2024.110287 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 18, 2024 Category: Radiology Authors: Chi Leung Chiang Kenneth Sik Kwan Chan Huaping Li Wai Tong Ng James Chung Hang Chow Horace Cheuk Wai Choi Ka On Lam Victor Ho Fun Lee Roger Kai Cheong Ngan Anne Wing Mui Lee Steven A Eschrich Javier F Torres-Roca Jason Wing Hon Wong Source Type: research

Re-irradiation versus systemic therapy for the management of local-regionally recurrent head and neck cancer
CONCLUSION: Although re-irradiation improved overall survival compared to systemic therapy for appropriately selected patients with local-regionally recurrent head and neck cancer, the relatively high risk of toxicity must be considered.PMID:38636710 | DOI:10.1016/j.radonc.2024.110278 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 18, 2024 Category: Radiology Authors: Allen M Chen Jeremy P Harris Rupali Nabar Tjoson Tjoa Yarah Haidar William B Armstrong Source Type: research

Comparison of 3-year local control using DAHANCA radiotherapy guidelines before and after implementation of five millimetres geometrical GTV to high-dose CTV margin
CONCLUSION: DAHANCA radiotherapy guidelines based on a geometrically generated isotropic CTV1 margin led to less variation in treatment volumes and between centres than previous guidelines. The transition towards consensus GTV-CTV1 margins did not influence local tumour control. The majority of local recurrences were inside CTV1 and covered by the prescription dose.PMID:38636711 | DOI:10.1016/j.radonc.2024.110284 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 18, 2024 Category: Radiology Authors: Ruta Zukauskaite Morten Horsholt Kristensen Jesper Grau Eriksen J ørgen Johansen Eva Sams øe Lars Johnsen Camilla Kj ær Lønkvist Cai Grau Christian R ønn Hansen Source Type: research

Comparing the effects of irradiation with protons or photons on neonatal mouse brain: Apoptosis, oncogenesis and hippocampal alterations
CONCLUSION: In-vivo experiments with radiosensitive mouse models improve our mechanistic understanding of the dependence of brain damage on radiation quality, thus having important implications in translational research.PMID:38614282 | DOI:10.1016/j.radonc.2024.110267 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 13, 2024 Category: Radiology Authors: Daniela Giovannini Francesca Antonelli Arianna Casciati Cinzia De Angelis Maria Denise Astorino Giulia Bazzano Emiliano Fratini Alessandro Ampollini Monia Vadrucci Evaristo Cisbani Paolo Nenzi Luigi Picardi Anna Saran Carmela Marino Mariateresa Mancuso Co Source Type: research

Postoperative radiotherapy results in 192 epithelial thymic tumours patients with 10  years of follow-up
CONCLUSION: Approximately one-third of the TET in our study experienced a LRR, mainly to the pleura, and 8% in total were in-field. The place of radiotherapy should be better defined in higher risk thymoma patients within prospective randomized studies.PMID:38614283 | DOI:10.1016/j.radonc.2024.110272 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 13, 2024 Category: Radiology Authors: Hugo Lopez Angela Botticella Farid Belkhir Benjamin Besse Elie Fadel Olaf Mercier Antonin Levy C écile Le Péchoux Source Type: research

Long-term survival outcomes and quality of life of image-guided proton therapy for operable stage I non-small cell lung cancer: A phase 2 study
CONCLUSION: Our findings suggest that IGPT provides effective disease control and survival in operable stage I NSCLC, particularly for peripheral lesions. Moreover, toxicity associated with IGPT was minimal, and patients reported favorable QOL.PMID:38614284 | DOI:10.1016/j.radonc.2024.110276 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 13, 2024 Category: Radiology Authors: Koichiro Nakajima Masanosuke Oguri Hiromitsu Iwata Yukiko Hattori Shingo Hashimoto Kento Nomura Kensuke Hayashi Toshiyuki Toshito Kenji Akita Fumiya Baba Hiroyuki Ogino Akio Hiwatashi Source Type: research

Comparing the effects of irradiation with protons or photons on neonatal mouse brain: Apoptosis, oncogenesis and hippocampal alterations
CONCLUSION: In-vivo experiments with radiosensitive mouse models improve our mechanistic understanding of the dependence of brain damage on radiation quality, thus having important implications in translational research.PMID:38614282 | DOI:10.1016/j.radonc.2024.110267 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 13, 2024 Category: Radiology Authors: Daniela Giovannini Francesca Antonelli Arianna Casciati Cinzia De Angelis Maria Denise Astorino Giulia Bazzano Emiliano Fratini Alessandro Ampollini Monia Vadrucci Evaristo Cisbani Paolo Nenzi Luigi Picardi Anna Saran Carmela Marino Mariateresa Mancuso Co Source Type: research

Postoperative radiotherapy results in 192 epithelial thymic tumours patients with 10  years of follow-up
CONCLUSION: Approximately one-third of the TET in our study experienced a LRR, mainly to the pleura, and 8% in total were in-field. The place of radiotherapy should be better defined in higher risk thymoma patients within prospective randomized studies.PMID:38614283 | DOI:10.1016/j.radonc.2024.110272 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 13, 2024 Category: Radiology Authors: Hugo Lopez Angela Botticella Farid Belkhir Benjamin Besse Elie Fadel Olaf Mercier Antonin Levy C écile Le Péchoux Source Type: research