Uncertainty-aware MR-based CT synthesis for robust proton therapy planning of brain tumour

CONCLUSION: The enhanced framework incorporates 3D uncertainty prediction and generates high-quality sCTs from MR images. The framework also facilitates conditioned robust optimisation, bolstering proton plan robustness against network prediction errors. The innovative feature of uncertainty visualisation and robust analyses contribute to evaluating sCT clinical utility for individual patients.PMID:38104781 | DOI:10.1016/j.radonc.2023.110056

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - December 17, 2023 Category: Radiology Authors: Xia Li Renato Bellotti Gabriel Meier Barbara Bachtiary Damien Weber Antony Lomax Joachim Buhmann Ye Zhang Source Type: research