Ten-year fracture risk in Japanese patients with myasthenia gravis: A comprehensive assessment using the fracture risk assessment tool
Myasthenia gravis (MG) is an immune disorder that causes muscle weakness with an increasing prevalence, particularly among the elderly in Japan. Glucocorticoid treatment for MG is problematic for bone health because of reduced bone density and increased fracture risk. The fracture risk assessment tool (FRAX ®) can estimate fracture risk, but its applicability in patients with MG remains uncertain. (Source: Journal of the Neurological Sciences)
Source: Journal of the Neurological Sciences - April 16, 2024 Category: Neurology Authors: Shingo Konno, Takafumi Uchi, Hideo Kihara, Hideki Sugimoto Source Type: research

Changes in ocular blood flow in patients with neovascular age-related macular degeneration after intravitreal injection of ranibizumab biosimilar and brolucizumab
ConclusionOur findings suggest that the short-term impact on OBF varies depending on the drug used for nAMD. (Source: International Ophthalmology)
Source: International Ophthalmology - April 16, 2024 Category: Opthalmology Source Type: research

Patients with diabetes and obesity exhibit characteristics in eating and coping behaviors and personality traits
ConclusionsThese results suggest that there are some characteristics in eating and coping behaviors and some personality traits between obese and non-obese patients with diabetes. Treatment based on such characteristics may be useful for patients with diabetes and obesity. (Source: Diabetology International)
Source: Diabetology International - April 16, 2024 Category: Endocrinology Source Type: research

Early experience and future prospects regarding use of newly developed surgical robot system, hinotori, in the field of urologic cancer surgery
AbstractIn the field of urology, robotic surgery has gained rapid and wide acceptance as a standard surgical approach in the majority of major surgeries over the last decade. To date, the da Vinci surgical system has been the dominant platform in robotic surgery; however, several newly developed robotic systems have recently been introduced in routine clinical practice. Of these, hinotori, the first made-in-Japan robotic system, is characterized by various unique and attractive features different from the existing system, and the use of this system has gradually increased mainly in urologic cancer surgeries, including radi...
Source: International Journal of Clinical Oncology - April 16, 2024 Category: Cancer & Oncology Source Type: research

PMDA regulatory update on approval and revision of the precautions for use of anticancer drugs: approval of nivolumab for unresectable advanced or recurrent epithelial skin malignancies in Japan
(Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - April 16, 2024 Category: Cancer & Oncology Source Type: research

SARS-CoV-2 seroprevalence among healthcare workers in a highly vaccinated Japanese medical center from 2020 –2023
Volume 20, Issue 1, December 2024 . (Source: Human Vaccines and Immunotherapeutics)
Source: Human Vaccines and Immunotherapeutics - April 16, 2024 Category: Allergy & Immunology Authors: Yan YanKanami ItoHiroshi FukudaShuko NojiriWataru UrasakiTakamasa YamamotoYuki HoriuchiSatoshi HoriKazuhisa TakahashiToshio NaitoYoko Tabea Department of General Medicine, Juntendo University Faculty of Medicine, Tokyo, Japanb Department of Safety and Hea Source Type: research

Wedge resection, segmentectomy, and lobectomy: oncologic outcomes based on extent of surgical resection for ≤2 cm stage IA non-small cell lung cancer
CONCLUSIONS: Patients with inferior performance status or lower baseline pulmonary function are more likely to receive wedge resection for clinical stage IA NSCLC ≤2 cm in size. For these small tumors, lobectomy, segmentectomy, and wedge resection provide comparable oncologic outcomes.PMID:38617767 | PMC:PMC11009583 | DOI:10.21037/jtd-23-1693 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Shaikha Al-Thani Abu Nasar Jonathan Villena-Vargas Sebron Harrison Benjamin Lee Jeffrey L Port Nasser Altorki Oliver S Chow Source Type: research

Temperature imaging inside fluid devices using a ratiometric near infrared (NIR-II/III) fluorescent Y < sub > 2 < /sub > O < sub > 3 < /sub > : Nd < sup > 3+ < /sup > , Yb < sup > 3+ < /sup > , Er < sup > 3+ < /sup > nanothermometer
Anal Sci. 2024 Apr 15. doi: 10.1007/s44211-024-00564-0. Online ahead of print.ABSTRACTLuminescence thermometry is a non-contact method that can measure surface temperatures and the temperature of the area where the fluorescent probe is located, allowing temperature distribution visualizations with a camera. Ratiometric fluorescence thermometry, which uses the intensity ratio of fluorescence peaks at two wavelengths with different fluorescence intensity dependencies, is an excellent method for visualizing temperature distributions independent of the fluorophore spatial concentration, excitation light intensity and absolute ...
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - April 15, 2024 Category: Chemistry Authors: Masakazu Umezawa Hikaru Haraguchi Gaku Sugawara Konosuke Sato Hiroyuki Kurahashi Teiji Oda Kyohei Okubo Kohei Soga Source Type: research

Collapse of zone 0 landing TEVAR (Najuta) and the development of higher brain dysfunction
J Cardiovasc Surg (Torino). 2024 Apr 15. doi: 10.23736/S0021-9509.24.12982-5. Online ahead of print.ABSTRACTAlthough thoracic endovascular repair (TEVAR)-specific complications often develop, stent-graft collapse is a rare, but fatal complication that requires attention. A 62-year-old male underwent TEVAR for a saccular distal arch aortic aneurysm. After the placement of the Gore TAG (W. L. Gore & Associates, Inc., Newark, DE, USA) from zones 2 to 4, a Najuta endograft (Kawasumi Laboratories, Inc., Tokyo, Japan) was deployed from zone 0. Neither intraoperative angiography nor postoperative contrast-enhanced computed to...
Source: The Journal of Cardiovascular Surgery - April 15, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Akito Imai Kisato Mitomi Masataka Sato Kanji Matsuzaki Taisuke Konishi Yasunori Watanabe Source Type: research

Wedge resection, segmentectomy, and lobectomy: oncologic outcomes based on extent of surgical resection for ≤2 cm stage IA non-small cell lung cancer
CONCLUSIONS: Patients with inferior performance status or lower baseline pulmonary function are more likely to receive wedge resection for clinical stage IA NSCLC ≤2 cm in size. For these small tumors, lobectomy, segmentectomy, and wedge resection provide comparable oncologic outcomes.PMID:38617767 | PMC:PMC11009583 | DOI:10.21037/jtd-23-1693 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Shaikha Al-Thani Abu Nasar Jonathan Villena-Vargas Sebron Harrison Benjamin Lee Jeffrey L Port Nasser Altorki Oliver S Chow Source Type: research

Temperature imaging inside fluid devices using a ratiometric near infrared (NIR-II/III) fluorescent Y < sub > 2 < /sub > O < sub > 3 < /sub > : Nd < sup > 3+ < /sup > , Yb < sup > 3+ < /sup > , Er < sup > 3+ < /sup > nanothermometer
Anal Sci. 2024 Apr 15. doi: 10.1007/s44211-024-00564-0. Online ahead of print.ABSTRACTLuminescence thermometry is a non-contact method that can measure surface temperatures and the temperature of the area where the fluorescent probe is located, allowing temperature distribution visualizations with a camera. Ratiometric fluorescence thermometry, which uses the intensity ratio of fluorescence peaks at two wavelengths with different fluorescence intensity dependencies, is an excellent method for visualizing temperature distributions independent of the fluorophore spatial concentration, excitation light intensity and absolute ...
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - April 15, 2024 Category: Chemistry Authors: Masakazu Umezawa Hikaru Haraguchi Gaku Sugawara Konosuke Sato Hiroyuki Kurahashi Teiji Oda Kyohei Okubo Kohei Soga Source Type: research

HPV Vaccine Issues in Japan: A review of our attempts to promote the HPV vaccine and to provide effective evaluation of the problem through social-medical and behavioral-economic perspectives
Vaccine. 2024 Apr 13:S0264-410X(24)00407-9. doi: 10.1016/j.vaccine.2024.03.080. Online ahead of print.ABSTRACTIn Japan, subsidies from local and national government programs for HPV vaccination of girls aged 13-16 began in 2010. By 2013, HPV vaccines were being used routinely for vaccinating girls aged 12-16 as part of its national immunization program. However, in June of 2013, in response to reports of possible adverse reactions to the vaccine, Japan's Ministry of Health, Labor, and Welfare (MHLW) announced a 'temporary suspension' of its governmental recommendation for HPV vaccination. The vaccination rate quickly dropp...
Source: Vaccine - April 15, 2024 Category: Allergy & Immunology Authors: Asami Yagi Yutaka Ueda Tadashi Kimura Source Type: research

Inter- and intra-observer variability of qualitative visual breast-composition assessment in mammography among Japanese physicians: a first multi-institutional observer performance study in Japan
CONCLUSIONS: Qualitative visual assessment of mammographic breast composition using the new Japanese classification revealed excellent intra-observer reproducibility. However, persistent inter-observer variability, presenting a challenge in establishing it as the gold standard in Japan.PMID:38619787 | DOI:10.1007/s12282-024-01580-8 (Source: Breast Cancer)
Source: Breast Cancer - April 15, 2024 Category: Cancer & Oncology Authors: Yoichi Koyama Kazuaki Nakashima Shunichiro Orihara Hiroko Tsunoda Fuyo Kimura Natsuki Uenaka Kanako Ban Yukiko Michishita Yoshihide Kanemaki Arisa Kurihara Kanae Tawaraya Masataka Taguri Takashi Ishikawa Takayoshi Uematsu Source Type: research

Wedge resection, segmentectomy, and lobectomy: oncologic outcomes based on extent of surgical resection for ≤2 cm stage IA non-small cell lung cancer
CONCLUSIONS: Patients with inferior performance status or lower baseline pulmonary function are more likely to receive wedge resection for clinical stage IA NSCLC ≤2 cm in size. For these small tumors, lobectomy, segmentectomy, and wedge resection provide comparable oncologic outcomes.PMID:38617767 | PMC:PMC11009583 | DOI:10.21037/jtd-23-1693 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Shaikha Al-Thani Abu Nasar Jonathan Villena-Vargas Sebron Harrison Benjamin Lee Jeffrey L Port Nasser Altorki Oliver S Chow Source Type: research