Incidence, Predictors, and Outcome Associated With Ventricular Tachycardia or Fibrillation in Patients Undergoing Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction
CONCLUSIONS: The results clearly indicated that VT/VF is still a serious complications of AMI. We need to identify patients at high risk of developing VT/VF for careful observation and appropriate intervention.PMID:37766557 | DOI:10.1253/circj.CJ-23-0023 (Source: Circulation Journal)
Source: Circulation Journal - September 28, 2023 Category: Cardiology Authors: Kenji Hanada Takahiko Kinjo Hiroaki Yokoyama Michiko Tsushima Maiko Senoo Hiroaki Ichikawa Fumie Nishizaki Shuji Shibutani Takashi Yokota Ken Okumura Hirofumi Tomita Source Type: research

Discover inspiring stories from the 100-year history of the Japan Endocrine Society; progress toward future successes
Endocr J. 2023;70(9):847-850. doi: 10.1507/endocrj.EJ20230323.NO ABSTRACTPMID:37766578 | DOI:10.1507/endocrj.EJ20230323 (Source: Endocrine Journal)
Source: Endocrine Journal - September 28, 2023 Category: Endocrinology Authors: Masatomo Mori Source Type: research

Assessment of factors associated with improved glycemic control after switching from intermittently scanned to real-time continuous glucose monitoring in Japanese patients with type 1 diabetes
Endocr J. 2023 Sep 26. doi: 10.1507/endocrj.EJ23-0125. Online ahead of print.ABSTRACTThe advantages of real-time continuous glucose monitoring (rtCGM) over intermittently scanned CGM (isCGM) reportedly include lower glycated hemoglobin (HbA1c) levels as well as reduced glycemic variability. However, there have been few studies of the effect of switching from isCGM to rtCGM on glycemic control, as well as the specific factors underlying any observed improvements. To that end, all patients with type 1 diabetes mellitus who used the DEXCOM rtCGM device (Terumo Corporation, Tokyo, Japan) at our institution were reviewed, and 1...
Source: Endocrine Journal - September 28, 2023 Category: Endocrinology Authors: Eijiro Yamada Yasuyo Nakajima Kazuhiko Horiguchi Shuichi Okada Masanobu Yamada Source Type: research

Boredom and engagement at work: do they have different antecedents and consequences?
This study aimed to demonstrate the empirical distinctiveness of boredom at work and work engagement in relation to their potential antecedents (job demands and job resources) and consequences (psychological distress and turnover intention) based on the Job Demands-Resources model. A three-wave longitudinal survey was conducted among registered monitors of an Internet survey company in Japan. The questionnaire included scales for boredom at work, work engagement, psychological distress, and turnover intention as well as participants' job characteristics and demographic variables. The hypothesized model was evaluated via st...
Source: Industrial Health - September 28, 2023 Category: Occupational Health Authors: Michiko Kawada Akihito Shimazu Daisuke Miyanaka Masahito Tokita Keiko Sakakibara Naana Mori Fuad Hamsyah Lin Yuheng Kojiro Shojima Wilmar B Schaufeli Source Type: research

Difference in Clinical Phenotype, Mutation Position, and Structural Change of RNF213 Rare Variants Between Pediatric and Adult Japanese Patients with Moyamoya Disease
This study included 151 Japanese patients with MMD. After performing targeted resequencing for all coding exons inRNF213, we investigated the clinical phenotype and statistically analyzed the genotype –phenotype correlation. We mappedRNF213 variants on a three-dimensional (3D) model of human RNF213 and analyzed the structural changes due to variants. TheRNF213 p.R4810K homozygous variant, p.R4810K heterozygous variant, and wild type were detected in 10 (6.6%), 111 (73.5%), and 30 (19.9%) MMD patients, respectively. In addition, 15 rare variants were detected in 16 (10.6%) patients. In addition to the influence of the p.R...
Source: Translational Stroke Research - September 28, 2023 Category: Neurology Source Type: research

A community cluster of influenza A(H3N2) virus infection with reduced susceptibility to baloxavir due to a PA E199G substitution in Japan, February to March 2023
A community cluster of influenza A(H3N2) caused by viruses with an E199G substitution in PA was detected in Nara, Japan, between February and March 2023. The three patients with these mutant viruses had not received antiviral treatment before specimen collection but patients in the same hospital had. The sequences of the mutant viruses were closely related, suggesting clonal spread in Nara. They showed reduced susceptibility to baloxavir in vitro; however, the clinical significance of the PA E199G substitution remains unclear. (Source: Eurosurveillance)
Source: Eurosurveillance - September 28, 2023 Category: Infectious Diseases Authors: Emi Takashita, Seiichiro Fujisaki, Hiroko Morita, Shiho Nagata, Hideka Miura, Yuki Matsuura, Saya Yamamoto, Shoko Chiba, Yumiko Inoue, Iori Minami, Sayaka Yoshikawa, Seiko Yamazaki, Noriko Kishida, Kazuya Nakamura, Masayuki Shirakura, Shinji Watanabe and Source Type: research

Association of personality traits with dental visit procrastination by Japanese university students
Procrastination is a psychological trait that causes individuals to put off doing things that need to be done. It has recently shown to result in the worsening of symptoms due to delays in seeking medical care... (Source: BioPsychoSocial Medicine)
Source: BioPsychoSocial Medicine - September 28, 2023 Category: Psychiatry & Psychology Authors: Yukitaka Hoshino, Shota Kataoka and Toshihiro Ansai Tags: Research Source Type: research

Efficacy and Safety of Azelnidipine as an Antihypertensive Compared to Amlodipine: A Systematic Review and Meta-analysis
ConclusionThough no significant difference between azelnidipine and amlodipine was found, in terms of reduction in SBP and DBP, azelnidipine reduced heart rate significantly compared to amlodipine.PROSPERO RegistrationCRD42023390361. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - September 28, 2023 Category: Cardiology Source Type: research

Probiotic properties of Bacillus subtilis DG101 isolated from the traditional Japanese fermented food natt ō
Spore-forming probiotic bacteria offer interesting properties as they have an intrinsic high stability, and when consumed, they are able to survive the adverse conditions encountered during the transit thorough the host gastrointestinal (GI) tract. A traditional healthy food, nattō, exists in Japan consisting of soy fermented by the spore-forming bacterium Bacillus subtilis natto. The consumption of nattō is linked to many beneficial health effects, including the prevention of high blood pressure, osteoporosis, and cardiovascular-associated disease. We hypothesize that the bacterium B. subtilis natto plays a key role in ...
Source: Frontiers in Microbiology - September 28, 2023 Category: Microbiology Source Type: research

Epidemiological and molecular evidence of intrafamilial transmission through sexual and vertical routes in Bahia, the state with the highest prevalence of HTLV-1 in Brazil
ConclusionSexual and vertical transmission routes contribute to the intrafamilial spread of HTLV-1 in the state of Bahia. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - September 28, 2023 Category: Tropical Medicine Authors: Aid ê Nunes da Silva Source Type: research

Efficacy of tyrosine kinase inhibitors in patients with non-small-cell lung cancer with performance status 4: a case series and review of the  literature
ConclusionsThis is the first case series to summarize the efficacy of TKIs in patients with NSCLC with a PS of 4. Additionally, this case series poses a question concerning the indication of TKIs for older patients with a PS of 4. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - September 28, 2023 Category: General Medicine Source Type: research

Transmit Radiant Individuality to Offspring (TRIO) study: investigating intergenerational transmission effects on brain development
Intergenerational transmission is a crucial aspect of human development. Although prior studies have demonstrated the continuity of psychopathology and maladaptive upbringing environments between parents and offspring, the underlying neurobiological mechanisms remain unclear. We have begun a novel neuroimaging research project, the Transmit Radiant Individuality to Offspring (TRIO) study, which focuses on biological parent-offspring trios. The participants of the TRIO study were Japanese parent-offspring trios consisting of offspring aged 10–40 and their biological mother and father. Structural and functional brain image...
Source: Frontiers in Psychiatry - September 28, 2023 Category: Psychiatry Source Type: research

Improved Symptom Change Enhances Quality of Dying in Patients With Advanced Cancer: An East Asian Cross-Cultural Study
CONCLUSIONS: Better quality of dying and death was associated with improved symptom control, especially for dyspnea and delirium. Integrating an outcome measurement for the quality of dying and death is important in the management of symptoms across the disease trajectory in a goal-concordant manner.PMID:37758042 | DOI:10.1093/oncolo/oyad269 (Source: The Oncologist)
Source: The Oncologist - September 27, 2023 Category: Cancer & Oncology Authors: Hsien-Liang Huang Ping-Jen Chen Masanori Mori Sang-Yeon Suh Chien-Yi Wu Jen-Kuei Peng Chih-Yuan Shih Chien-An Yao Jaw-Shiun Tsai Tai-Yuan Chiu Yusuke Hiratsuka Sun-Hyun Kim Tatsuya Morita Takashi Yamaguchi Satoru Tsuneto David Hui Shao-Yi Cheng Source Type: research

Inactivation of coxsackievirus B5 by free chlorine under conditions relevant to drinking water treatment
In this study, we investigated the inactivation efficiency of coxsackievirus B5 (CVB5) by free chlorine using actual water samples collected from four full-scale drinking water treatment plants in Japan under strict turbidity management (less than 0.14 NTU) over a 12-month period. It was found that chlorine disinfection of CVB5 might not be affected by water quality. Japanese turbidity management might play an indirect role in controlling the efficiency of chlorine disinfection.PMID:37756198 | DOI:10.2166/wh.2023.178 (Source: Journal of Water and Health)
Source: Journal of Water and Health - September 27, 2023 Category: Environmental Health Authors: Vu Duc Canh Shotaro Torii Tippawan Singhopon Hiroyuki Katayama Source Type: research

Field demonstration of UV-LED disinfection at small and decentralized water facilities
This study demonstrates the effectiveness of UV-LED technology for water disinfection in small and decentralized water supply systems.PMID:37756202 | DOI:10.2166/wh.2023.192 (Source: Journal of Water and Health)
Source: Journal of Water and Health - September 27, 2023 Category: Environmental Health Authors: Kumiko Oguma Source Type: research