Diamonds grown without extreme pressures
Diamonds, the hardest material, may have gotten easier to make. Researchers today report a new way to grow synthetic diamonds without the crushing pressures normally required. Although the approach yields crystals no bigger than 100 nanometers across—about the size of a typical virus—researchers suspect it may eventually yield larger crystals and the extended diamond films that are prized for advanced electronics and optics. “The technique is quite interesting,” says John Ciraldo, who specializes in diamond growth at WD Advanced Materials. “If they could make larger single crystals that would be fantastic,...
Source: Science of Aging Knowledge Environment - April 24, 2024 Category: Geriatrics Source Type: research

China set to fetch first rocks from mysterious far side of the Moon
There’s a giant hole on the backside of the Moon. The South Pole–Aitken (SPA) Basin, the Moon’s largest and oldest impact crater, is more than 2500 kilometers wide and 8 kilometers deep—nearly big enough to swallow two Indias and hide the Himalayas. Now, China plans to land in it. The basin may have been blasted out during a barrage of asteroids that pummeled Earth and other inner Solar System bodies billions of years ago, and scientists have long wanted to get their hands on SPA rocks to test the idea. The China National Space Administration (CNSA) aims to provide them with the Chang’e-6 mission, which sci...
Source: Science of Aging Knowledge Environment - April 24, 2024 Category: Geriatrics Source Type: research

A Study on the Scientific Reliability of Notification Data in the Foods with Function Claims
Shokuhin Eiseigaku Zasshi. 2024;65(2):31-39. doi: 10.3358/shokueishi.65.31.ABSTRACTWe conducted a comprehensive survey of Foods with Function Claims (FFC) submitted from April to August 2022 to examine the scientific reliability of the systematic review (SR), which is the basis for functional claims. The results of the review of 611 functional claims for 398 products showed that there were 121 functionally active substances and 87 health claims (Hc) that were labeled, with some functionally active substances having multiple functions. SRs, meta-analyses, and clinical studies were submitted as the basis of functionality for...
Source: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan - April 24, 2024 Category: Food Science Authors: Ippei Suzuki Tsuyoshi Chiba Kayo Yoshimatsu Jun Takebayashi Source Type: research

Comparison of DNA Extraction Methods for Processed Foods Containing Soybean or Maize
In this study, the equivalence testing of the techniques employed for DNA extraction from processed foods containing soybean or corn was conducted. In this study, the equivalence testing of the techniques employed for DNA extraction from processed foods containing soybean or maize was conducted. The silica membrane-based DNA extraction kits, GM quicker 4 and DNeasy Plant Maxi Kit (Maxi Kit), as an existing method were compared. GM quicker 4 was considered to be equivalent to or better than Maxi Kit.PMID:38658344 | DOI:10.3358/shokueishi.65.25 (Source: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan)
Source: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan - April 24, 2024 Category: Food Science Authors: Tomohiro Egi Reona Takabatake Masahiro Kishine Keisuke Soga Satoko Yoshiba Norihito Shibata Kazunari Kondo Yasuharu Takashima Source Type: research

Incidence of Pure Orbital Fractures with Concomitant Lacrimal Drainage System Injury in the Japanese Population: A Retrospective Study
CONCLUSION: There is a 1.4% incidence rate of pure orbital fractures with concomitant lacrimal drainage system injuries among the Japanese population included in this study. Inferomedial orbital strut fractures and orbital floor fracture lateral to the infraorbital groove were found to have higher association with lacrimal drainage system injuries.PMID:38656194 | DOI:10.1080/08820538.2024.2346762 (Source: Seminars in Ophthalmology)
Source: Seminars in Ophthalmology - April 24, 2024 Category: Opthalmology Authors: Steffani Krista Someda Jose Miguel Ambat Hidetaka Miyazaki Yasuhiro Takahashi Source Type: research

Cost-effectiveness analysis of transcatheter aortic valve implantation in aortic stenosis patients at low- and intermediate-surgical risk in Japan
CONCLUSIONS: TAVI was dominant and cost-effective compared to SAVR in intermediate- and low-risk patients, respectively. These results suggest that TAVI can provide meaningful value to Japanese patients relative to SAVR, at a reasonable incremental cost for patients at low surgical risk and potentially resulting in cost-savings in patients at intermediate surgical risk.PMID:38654415 | DOI:10.1080/13696998.2024.2346397 (Source: Journal of Medical Economics)
Source: Journal of Medical Economics - April 24, 2024 Category: Health Management Authors: Junjiro Kobayashi Suzanne J Baron Kensuke Takagi Christin A Thompson Xiayu Jiao Kaoru Yamabe Source Type: research

The potential of lemon peel powder as an additive in layer quails (Coturnix coturnix Japonica): An experimental study
An Acad Bras Cienc. 2024 Apr 22;96(1):e20230640. doi: 10.1590/0001-3765202420230640. eCollection 2024.ABSTRACTThe current research intended to examine the impact of dietary lemon peel powder (LPP) on laying quail performance, egg quality criteria, and the antioxidant capacity of the yolk. A total of 120 female Japanese quails (272.6±9.3 g), aged 21 weeks, were allotted to 6 trial groups, each with 5 replicates of 4 quails. Additions of 0, 1, 2, 3, 4, or 5 g/kg of LPP to the basal diet were used to create the treatment groups. Quails were fed ad libitum for 70 days. Neither performance parameters nor egg production was aff...
Source: An Acad Bras Cienc - April 24, 2024 Category: Science Authors: Ainhoa Sarmiento- Garc ía Osman Olgun Esra T G ül G özde Kilinç Alp önder Yildiz Source Type: research

Association between multimorbidity and utilization of medical and long-term care among older adults in a rural mountainous area in Japan
CONCLUSION: Multimorbidity was dominant among late-stage older adults living in depopulated mountainous areas of Japan, and the number of morbidities was associated with higher economic costs of medical and long-term care services. Mitigating the impact of multimorbidity among older adults in depopulated regions of Japan is an urgent challenge. Future research should investigate the degree and effectiveness of social protections for vulnerable older adults living in remote areas.PMID:38655230 | PMC:PMC11033674 | DOI:10.2185/jrm.2023-049 (Source: Rural Remote Health)
Source: Rural Remote Health - April 24, 2024 Category: Rural Health Authors: Yuki Kuwabara Toshihiro Hamada Tsubasa Nakai Maya Fujii Aya Kinjo Yoneatsu Osaki Source Type: research

How do social networks, perception of social isolation, and loneliness affect depressive symptoms among Japanese adults?
ConclusionsResults indicate that interventions of psychological approaches, such as cognitive –behavioral therapy, are effective in reducing the perception of social isolation and loneliness, which may lead to the prevention of depressive symptoms. Future longitudinal studies are expected to refine and strengthen the proposed model. (Source: PLoS One)
Source: PLoS One - April 24, 2024 Category: Biomedical Science Authors: Natsuho Kushibiki Source Type: research

Safety, Tolerability, and Pharmacokinetics of Oral BI 1358894 in Healthy Japanese Male Volunteers
ConclusionBI 1358894 was well tolerated with a favorable pharmacokinetic profile in Japanese male HVs, similar to findings from a previous study in Caucasian male HVs.Trial RegistrationClinicalTrials.gov (NCT03875001; 08-Mar-2019). (Source: Clinical Drug Investigation)
Source: Clinical Drug Investigation - April 24, 2024 Category: Drugs & Pharmacology Source Type: research

An unexpected case of tetanus in a fully immunized 20-year-old female: a case report
ConclusionThe present case serves as a stark reminder that tetanus may still occur in young, immunized individuals. Patients with a history of immunization may have a better prognosis than those with no immunizations. (Source: International Journal of Emergency Medicine)
Source: International Journal of Emergency Medicine - April 24, 2024 Category: Emergency Medicine Source Type: research

Association between the quantity of stroke care units and the complement of neurosurgical and neurology specialists in Japan: A retrospective study
Initial treatment in a stroke unit (SU) can reduce the mortality of stroke victims, increase the rate of discharge to home, and decrease the amount of time spent in the hospital. The effectiveness of an SU has also been proven in a meta-analysis. Stroke units have been established in various locations in Europe since 1990, and the medical system for managing the acute phase of stroke has improved1, 2. The Japanese Stroke Association recommends in its Stroke Treatment Guidelines 2021 that acute stroke patients should be treated by a multidisciplinary stroke team in an SU that provides intensive care and early rehabilitation...
Source: Journal of Stroke and Cerebrovascular Diseases - April 24, 2024 Category: Neurology Authors: Kentaro Hara, Masato Kanda, Hiroyo Kuwabara, Yoshio Kobayashi, Takahiro Inoue Source Type: research

An analysis of the factors involved in IOL decentration after phacoemulsification using CASIA 2 anterior  segment optical coherence tomography
ConclusionGreater crystalline lens diameter was associated with greater decentration and with greater ITS. Day-one IOL decentration seems to be the main determinant of final IOL decentration. (Source: International Ophthalmology)
Source: International Ophthalmology - April 24, 2024 Category: Opthalmology Source Type: research

Long-term effectiveness and safety of upadacitinib for Japanese patients with moderate-to-severe atopic dermatitis: a real-world clinical study
CONCLUSIONS: Upadacitinib was therapeutically effective and tolerable for moderate-to-severe AD through 48 weeks in real-world clinical practice.PMID:38653561 | DOI:10.1080/09546634.2024.2344591 (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - April 23, 2024 Category: Dermatology Authors: Teppei Hagino Hidehisa Saeki Eita Fujimoto Naoko Kanda Source Type: research

The Transaxillary Approach as a Direct Route in the Management of Upper Thoracic Spine Pathology: A Technical Note with Case Series
Asian Spine J. 2024 Apr 23. doi: 10.31616/asj.2023.0175. Online ahead of print.ABSTRACTThis retrospective case series of prospective data aims to describe the transaxillary approach for the treatment of upper thoracic spine pathology. Various surgical techniques and approaches have been reported across the literature to address upper thoracic spine pathology, including the cervicothoracic approach, anterior transsternal approach, posterolateral approach, supraclavicular approach, and lateral parascapular approaches. These techniques are invasive. A minimally invasive, less morbid, and direct access approach to the patholog...
Source: Asian Spine Journal - April 23, 2024 Category: Orthopaedics Authors: Syed Ifthekar Ju-Wan Seuk Ui Dong Hwang Hyung Chang Lee Sang-Ho Lee Junseok Bae Source Type: research