Surgery of the chest wall: indications, timing and technical aspects.
Authors: Petrella F, Spaggiari L PMID: 32055416 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - February 15, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Sternochondral replacement: use of cadaveric allograft for the reconstruction of anterior chest wall.
Conclusions: This technique for sternal replacement in our experience can be considered safe with long term results, providing optimal chest wall stability. The allograft resulted well-tolerated permitting an optimal graft integration in the host. PMID: 32055417 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - February 15, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Costal cartilage resection for the treatment of slipping rib syndrome (Cyriax syndrome) in adults.
Authors: Mazzella A, Fournel L, Bobbio A, Janet-Vendroux A, Lococo F, Hamelin EC, Icard P, Alifano M Abstract Background: Slipping rib syndrome is an overlooked cause of low chest or upper abdominal pain. Costal cartilage excision has been described as an effective treatment of this disorder. We review our experience with surgically treated slipping rib syndrome in the adult patient. Methods: This is a single institution retrospective analysis from January 2000 to March 2019 of adult patients operated on for treatment of a slipping rib syndrome. Results: Nineteen patients were diagnosed with slipping rib sy...
Source: Journal of Thoracic Disease - February 15, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Anterior chest wall resection and sternal body wedge for primary chest wall tumour: reconstruction technique with biological meshes and titanium plates.
Authors: Sandri A, Donati G, Blanc CD, Nigra VA, Gagliasso M, Barmasse R Abstract Chest wall tumours are heterogeneous neoplasms, either primary or metastatic, with a malignancy rate of 50%. Surgical resection is one of the mainstays of the treatment, however, chest wall resections can be particularly challenging depending onto the resection size, site and patient habitus. The surgical strategy should be carefully analysed preoperatively, keeping in mind the need of an oncological radical resection (R0) in accordance to the reconstruction principles elicited by le Roux and Sherma since 1983, which include restoring...
Source: Journal of Thoracic Disease - February 15, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Chest wall resection and reconstruction for lung cancer: surgical techniques and example of integrated multimodality approach.
Authors: Loi M, Mazzella A, Desideri I, Fournel L, Hamelin EC, Icard P, Bobbio A, Alifano M PMID: 32055420 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - February 15, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Sternectomy for primary chondrosarcoma.
Authors: Collaud S, Stork T, Valdivia D, Tokuishi K, Aigner C PMID: 32055421 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - February 15, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Radioisotope-guided localization and resection of non-palpable focal lesion of the rib.
Authors: Petrella F, Lo Iacono G, Casiraghi M, Gherzi L, Prisciandaro E, Rampinelli C, Colandrea M, Grana CM, Spaggiari L PMID: 32055422 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - February 15, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Chest wall resection and reconstruction by composite prosthesis for locally recurrent breast carcinoma.
Authors: Petrella F, Lo Iacono G, Casiraghi M, Gherzi L, Prisciandaro E, Garusi C, Spaggiari L PMID: 32055423 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - February 15, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

MRI-guided segmental sternectomy for impalpable intraosseous lesion.
Authors: Petrella F, Casiraghi M, Filippi N, Orlandi R, Alliata A, Lo Iacono G, Funicelli L, Rizzo S, Spaggiari L PMID: 32055424 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - February 15, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Extensive abdominal and chest wall resection and reconstruction for invasive squamous cell carcinoma of the skin.
Authors: Ferrigno P, Monaci N, Pangoni A, Comacchio G, Natale G, Faccioli E, Zuin A, Dell'Amore A, Rea F PMID: 32055425 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - February 15, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

"J Thorac Dis"[ta]; +103 new citations
103 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "J Thorac Dis"[ta] These pubmed results were generated on 2020/02/09PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - February 9, 2020 Category: Respiratory Medicine Tags: Report Source Type: research

Impact of clinical features of epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC) patients on osimertinib efficacy.
Authors: Lazzari C, Gregorc V, Santarpia M PMID: 31903227 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Helping patients with lung cancer choose between surgery or stereotactic body radiotherapy: the importance of the patient experience.
Authors: MacManus M, De Abreu Lourenco R, Hegi-Johnson F PMID: 31903228 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Management of chronic obstructive pulmonary disease-A position statement of the South African Thoracic Society: 2019 update.
Authors: Abdool-Gaffar MS, Calligaro G, Wong ML, Smith C, Lalloo UG, Koegelenberg CFN, Dheda K, Allwood BW, Goolam-Mahomed A, van Zyl-Smit RN PMID: 31903229 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Single- versus two-port video-assisted thoracic surgery in mediastinal tumor: a propensity-matched study.
Conclusions: In this retrospective study, our experiences have shown that SP-VATS is a safe and promising technique and is not inferior to the TP-VATS. PMID: 31903230 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Retrospective immunohistological study of autopsied lungs in patients with acute exacerbation of interstitial pneumonia managed with extracorporeal membrane oxygenation.
Conclusions: The lungs of mechanically ventilated AE-IP patients treated with V-V ECMO had decreased fibrosis, endothelial injury, and inflammation. This finding suggests the lung-protective efficacy of adjunctive V-V ECMO therapy. PMID: 31903231 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Early surgical myocardial revascularization in non-ST-segment elevation acute coronary syndrome.
Conclusions: Early revascularized patients showed a higher level of illness. However, results of early CABG were comparable to those following delayed revascularization. Moreover, EuroSCORE II was determined as independent risk factors for mortality. PMID: 31903232 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

The effect of PD-L1/PD-1 immunotherapy in the treatment of squamous non-small-cell lung cancer: a meta-analysis of randomized controlled clinical trials.
Authors: Li S, Zhang S, Liu J, Yang C, Zhang L, Cheng Y Abstract Background: This meta-analysis evaluated the efficacy of PD-L1/PD-1 immunotherapy compared with chemotherapy in IIIB or IV or recurrent squamous non-small cell lung cancer (NSCLC) patients. Methods: We performed a literature search on the PubMed, EMBASE, Web of Science, and Cochrane databases, in addition to the abstracts from major conference proceedings of the European Society for Medical Oncology (ESMO), the American Society of Clinical Oncology (ASCO), and the World Conference on Lung Cancer (WCLC) from 2004 to May 2019. Randomized controlled ...
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Antiangiogenic effect of crocin on breast cancer cell MDA-MB-231.
Conclusions: Crocin has an anti-angiogenesis effect that may be correlated to the decreased expression of CD34. Crocin is likely to be involved in the regulation of molecules in the angiogenesis pathway. PMID: 31903234 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Safety outcomes in advanced non-small-cell lung cancer patients treated with first-line platinum-based regimens in the United States.
Conclusions: While EMR data have limitations, the real-world safety outcome with individual chemotherapy regimen could be considered for the better selection of platinum-based therapies in NSCLC. PMID: 31903235 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Misinterpretation of allergic bronchopulmonary aspergillosis/allergic bronchopulmonary mycosis due to diverse characteristics in different clinical stages.
Conclusions: This study highlights the importance of increasing awareness and understanding of non-Aspergillus-ABPM among physicians and draws attention to the need for establishing more elaborate diagnostic criteria for non-Aspergillus-ABPM, which is a rare kind of disease. PMID: 31903236 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

The association between plasma fibrinogen levels and lung cancer: a meta-analysis.
Conclusions: The summary results indicated that plasma fibrinogen was a marker of prognosis and clinicopathological characteristics in lung cancer. PMID: 31903237 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Modified McKeown procedure with uniportal thoracoscope for upper or middle esophageal cancer: initial experience and preliminary results.
Conclusions: Modified McKeown minimally invasive esophagectomy (MIE) with uniportal thoracoscopy seems to be a feasible option for patients with upper or middle esophageal cancer. Larger studies with longer follow-up are needed to further investigate this approach. PMID: 31903238 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

The prognostic value of tumor mutation burden in EGFR-mutant advanced lung adenocarcinoma, an analysis based on cBioPortal data base.
Authors: Jiao XD, He X, Qin BD, Liu K, Wu Y, Liu J, Hou T, Zang YS Abstract Background: Tumor mutation burden (TMB) is novel biomarker of promising predict value in prediction of immune checkpoint inhibitors (ICPis) in non-small cell lung cancer (NSCLC). However, the distribution of TMB in epidermal growth factor receptor (EGFR)-mutant advanced lung adenocarcinoma (LUAD) patients and the impact on overall survival (OS) time are not well demonstrated. Methods: Information regarding gene mutations and patients' survival time in advanced LUAD was downloaded from The Cancer Genome Atlas (TCGA) database. The diversi...
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Application of radiomics signature captured from pretreatment thoracic CT to predict brain metastases in stage III/IV ALK-positive non-small cell lung cancer patients.
Conclusions: We identified one wavelet texture feature derived from pretreatment thoracic CT that presented potential in predicting BM in stage III/IV ALK-positive NSCLC patients. This could be beneficial to risk stratification for such patients. Further investigation is necessary to include expanded sample size investigation and external multicenter validation. PMID: 31903240 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

A phase II study of concurrent nab-paclitaxel/carboplatin combined with thoracic radiotherapy in locally advanced squamous cell lung cancer.
Conclusions: Concurrent nab-paclitaxel, carboplatin, and thoracic radiotherapy was shown to be an effective regimen for patients with unresectable locally advanced squamous cell lung cancer; however, further study should exercise caution due to the severe radiation esophagitis. PMID: 31903241 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Use of new cannulated screws for primary sternal closure in high risk patients for sternal dehiscence.
Conclusions: In our clinical experience with high risk patients, this surgical option suggests that there is evidence of an effective stabilization of standard sternal closure and this option seems a promising technique to prevent the domino effect which starts from the xifoid bone and proceeds to the manubrium with the effect of leading to sternal instability which is the first step to mediastinitis. PMID: 31903242 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Algorithm-based troubleshooting to manage bleeding during thoracoscopic anatomic pulmonary resection.
Conclusions: Thoracoscopic anatomic pulmonary resection is feasible and safe if the surgeon performs appropriate hemostasis, although vascular hazards might be inherent during thoracoscopic anatomic pulmonary resection, regardless of the surgeon's experience. PMID: 31903243 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Relationship between pulmonary function and brachial-ankle pulse wave velocity in coal miners in northern China.
Authors: Yan X, Sun L, Ma M, Liu J, Wu S, Cao J Abstract Background: To investigate the relationship between pulmonary function and brachial-ankle pulse wave velocity (baPWV). Methods: A cross-sectional study was conducted. A total of 11,388 people with complete pulmonary function test and baPWV data and who participated in both the health examination of the Kailuan Occupational Disease Prevention and Treatment Center in 2014-2016 and the health checkup of the Kailuan Group in 2012 and 2014 were selected as subjects. The study population was divided into four groups by forced vital capacity (FVC) quartiles (group 1: FVC
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Pulmonary function is implicated in the prognosis of metastatic non-small cell lung cancer but not in extended disease small cell lung cancer.
Conclusions: Careful attention is required when chemotherapeutic agents are administered to patients with metastatic NSCLC with accompanying COPD with a FEV1 value of less than 80% predicted. PMID: 31903245 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Therapeutic issues with, and long-term outcomes of, pulmonary mycobacterial tuberculosis treatment in patients with autoimmune rheumatic diseases.
Conclusions: Clinicians may encounter difficulties when treating PTB in patients with RD. Despite the favorable long-term outcomes of RD patients, the outcomes of individual patients such as those with systemic lupus erythematosus (SLE) should be interpreted with caution during post-therapy follow-up. PMID: 31903246 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Platelet-to-lymphocyte ratio is an independent prognosticator in patients with esophageal squamous cell carcinoma receiving esophagectomy.
Authors: Chen LC, Li SH, Lo CM, Chen YH, Huang SC, Wang YM, Chou SY, Lu HI Abstract Background: Systemic inflammation response is a crucial prognostic factor for various cancers. The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are two inflammation-based prognostic scores. The significance of preoperative NLR and PLR in patients with esophageal squamous cell carcinoma (ESCC) receiving curative esophagectomy remains largely undefined. Hence, this study aimed to evaluate the significance of preoperative NLR and PLR in patients with ESCC receiving curative esophagectomy in southern Taiwa...
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Correlation between PD-L1 expression and clinicopathological characteristics of non-small cell lung cancer: A real-world study of a large Chinese cohort.
Authors: Jin Y, Shen X, Pan Y, Zheng Q, Chen H, Hu H, Li Y Abstract Background: Programmed death ligand-1 (PD-L1) is a predictive marker of anti-programmed death protein 1 (PD-1)/PD-L1 therapies for non-small cell lung cancer (NSCLC). However, little is known between PD-L1 expression and the clinicopathological characteristics of NSCLC in the Chinese population in a real-world setting. Methods: We analyzed PD-L1 expression by immunohistochemistry (IHC) in NSCLC patients using the 22C3 clone on the Dako Autostainer Link 48 platform. We then examined the associations of PD-L1 expression with clinicopathological c...
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Expression and significance of c-kit and epithelial-mesenchymal transition (EMT) molecules in thymic epithelial tumors (TETs).
Authors: Wu Z, Xue S, Zheng B, Ye R, Xu G, Zhang S, Zeng T, Zheng W, Chen C Abstract Background: To investigate the expression and significance of c-kit and epithelial-mesenchymal transition (EMT) molecules (E-cadherin, N-cadherin, Twist, Snail) in thymic epithelial tumors (TETs). Methods: The tissue microarray technology and immunohistochemistry MaxVisionTM-use kit were used to detect the expression of c-kit and EMT molecular markers in 150 cases of paraffin sections of TET tissue and analysis the correlation between c-kit and EMT molecules and explore the malignancy and the relationship of clinicopathological...
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Phenotypic and genotypic characterization of levofloxacin- and moxifloxacin-resistant Mycobacterium tuberculosis clinical isolates in southern China.
Conclusions: Mutations in QRDR(s) were concomitantly associated with Beijing and non-Beijing genotypes. The prevalence of resistance and cross-resistance between LVX and MXF in MTB isolates from southern China was immensely higher than other countries. Our valuable findings provide the substantial implications to improve the reliability of genotypic diagnostic tests relying on potential resistance conferring mutations in entire gyr genes. PMID: 31903250 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Molecular epidemiology of respiratory viruses among Malaysian Young children with a confirmed respiratory infection during 2014-2015.
Conclusions: The use of molecular assay as a routine diagnostic in the hospitals can improve the diagnosis and management of respiratory tract infections among children. PMID: 31903251 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Predicting in-hospital rupture of type A aortic dissection using Random Forest.
Conclusions: An easy-to-use tool to predict in-hospital rupture for TAAD patients was developed and validated (http://47.107.228.109/). Periaortic hematoma is the strongest predictor. Simple clinical information such as syncope can be very useful in in-hospital rupture risk stratification. PMID: 31903252 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

The powered vascular staple (PVS) versus conventional powered linier cutter (PLC) for the application of bronchial transection in thoracoscopic anatomic segmentectomy.
Conclusions: PVS is a smoother and easier instrument and has the same effectiveness and security as PLC. It leads to reduced operation difficulty and potential intraoperative complications. PMID: 31903253 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Comparison of long-term outcomes between radical esophagectomy and definitive chemoradiotherapy in patients with clinical T1bN0M0 esophageal squamous cell carcinoma.
Conclusions: The appreciable developments in radiation technology have enabled the achievement of comparable long-term outcomes in the chemoradiotherapy group compared with the esophagectomy group in patients with clinical T1bN0M0 thoracic ESCC. PMID: 31903254 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Nebulized dexmedetomidine-lidocaine inhalation as a premedication for flexible bronchoscopy: a randomized trial.
Authors: Gu W, Xu M, Lu H, Huang Q, Wu J Abstract Background: Dexmedetomidine plus opioid infusion after topical anaesthesia with nebulized lidocaine for cough suppression is a commonly used method for flexible bronchoscopy. Recently, the use of dexmedetomidine as an additive to local anaesthetics has been reported to have several advantages over conventional intravenous administration. However, there are no data regarding the use of nebulized dexmedetomidine-lidocaine for topical anaesthesia as a premedication for flexible bronchoscopy. Therefore, this study compared the tolerability and safety of nebulized dexmed...
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Recombinant human thrombopoietin combined with interleukin-2 improves the effects of chemosensitivity and thrombocytopenia on a basic gemcitabine and carboplatin combination therapy for non-small cell lung cancer in a nude mouse model.
Conclusions: The supplementation of rhTPO and IL-2 to a GC regime effectively reduced tumor sizes and restored the platelet count in a human lung cancer mouse model. PMID: 31903256 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Preoperative computed tomography-guided pulmonary nodule localization augmented by laser angle guide assembly.
Conclusions: LAGA enhanced the precision of POCTGL by optimizing targeting precision and decreasing repeated punctures, which minimized complications, such as pneumothorax. PMID: 31903257 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Technical results, clinical efficacy and predictors of outcome of intercostal arteries embolization for hemothorax: a two-institutions' experience.
Conclusions: ICA embolization was found to be a safe and effective method in treating hemothorax caused by active ICA haemorrhage. Careful pre-embolization evaluation may be required for patient with low haemoglobin levels and haematocrit, hepatic comorbidities and active haemorrhage from more than one artery. PMID: 31903258 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Incidence and risk factors of readmission after esophagectomy for esophageal cancer.
Conclusions: Readmission within 30 days after esophagectomy was determined to be related to postoperative anastomotic leakage and wound problems whereas the vocal cord palsy was not. PMID: 31903259 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Root reconstruction for proximal repair in acute type A aortic dissection.
Conclusions: The indication of root management of ATAAD is based on the diameter of aortic root, structure of aortic root, and the dissection involvement. For most ATAAD patients, aortic root reinforcement reconstruction is a feasible and safe method. PMID: 31903260 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

"Aorta-clamp" technique for surgical repair of acute type A aortic dissection-5 min circulatory arrest at 30 °C.
Conclusions: Using the "aorta-clamp" technique with continual bilateral antegrade cerebral perfusion, total arch replacement combined with an elephant trunk implantation can be performed under five minutes of mild (30 °C) HCA. Our data suggest that this technique for the surgical repair of AAAD is a safe, feasible and effective surgical approach with satisfactory early outcomes. PMID: 31903261 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Efficacy and safety of bevacizumab combined with chemotherapy in symptomatic brain metastases from lung adenocarcinoma: a retrospective analysis.
Conclusions: This study showed bevacizumab combined with chemotherapy could effectively control intracranial lesions, relieve symptoms, and improve the quality of life and survival of patients with brain metastases from lung adenocarcinoma. Serum baseline VEGF may be a predictor of efficacy of bevacizumab plus chemotherapy in the treatment of brain metastases from lung adenocarcinoma. PMID: 31903262 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Natural evolvement of lung tumors induced by N-ethyl-N-nitrosourea (ENU) and the impact of a high sucrose-high fat diet on tumor evolvement assessed by tumor histology in inbred BALB/c and C57BL/6J mice.
Conclusions: The observed histological changes indicated that lung tumors were developed at different times and evolved at different paces. The HSHF diet accelerated the course of tumor evolvement. Tumor cells with fatty changes might be induced by the HSHF diet. PMID: 31903263 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Outcomes and risk factors identification in urgent lung transplantation: a multicentric study.
Conclusions: ULT program allows transplantation in a significant percentage of patients with acceptable results. Pre-operative recipient selection is mandatory to improve clinical outcomes. PMID: 31903264 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Predictors of blood loss in lung transplant surgery-a single center retrospective cohort analysis.
Authors: Grande B, Oechslin P, Schlaepfer M, Seifert B, Inci I, Opitz I, Spahn DR, Weder W, Zalunardo M Abstract Background: This retrospective study aims to identify clinical predictors of intraoperative blood loss during lung transplantation. While for other surgical specialties predictors of blood loss have been identified such as previous likewise located surgery, poor preoperative health status of patients, blood coagulation status, and use of extra corporeal circulation, predictors of blood loss during lung transplantation are not yet established. Methods: A total of 326 lung transplants were performed be...
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research