Correlation with spontaneous pneumothorax and weather change, especially warm front approaching
CONCLUSIONS: Onset of PSP may correlate with the increased temperature and humidity, seen with an approaching of warm front.PMID:33841950 | PMC:PMC8024831 | DOI:10.21037/jtd-20-3395 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Yuka Kaneko Yoshihiro Utsushikawa Hiroyuki Deguchi Makoto Tomoyasu Satoshi Kudo Wataru Shigeeda Ryuichi Yoshimura Hironaga Kanno Hajime Saito Source Type: research

The recent 10-year landscape of aortic dissection research: a bibliometric analysis
CONCLUSIONS: This study provides interesting insights into the AD scientific landscape in recent 10 years and generates some objective evidence for comprehensive understanding and evaluation of this field. This investigation may ultimately inform managers, researchers and policymakers.PMID:33841951 | PMC:PMC8024840 | DOI:10.21037/jtd-20-3272 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Jinlin Wu Rui Zhao Donglin Zhuang Jiade Zhu Haiyun Zheng Jimei Chen Source Type: research

Recurrence of primary spontaneous pneumothorax following bullectomy with pleurodesis or pleurectomy: A retrospective analysis
CONCLUSIONS: Bullectomy with pleurectomy and pleurodesis demonstrated a 0% recurrence rate for the treatment of primary spontaneous pneumothorax in this study. Statistical significance was not achieved in univariable or multivariable analyses comparing recurrence rates for the surgical approaches. A multi-center randomized controlled trial with longer follow-up than previously performed is needed to confirm these preliminary findings and optimize surgical management of primary spontaneous pneumothorax.PMID:33841952 | PMC:PMC8024846 | DOI:10.21037/jtd-20-3257 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Shawn Brophy Kelly Brennan Daniel French Source Type: research

The preoperative glomerular filtration rate predicts new-onset postoperative atrial fibrillation in patients with hypertrophic obstructive cardiomyopathy who undergo isolated septal myectomy
J Thorac Dis. 2021 Mar;13(3):1612-1623. doi: 10.21037/jtd-20-3164.ABSTRACTBACKGROUND: Few studies have focused on new-onset postoperative atrial fibrillation in patients with hypertrophic obstructive cardiomyopathy who have undergone septal myectomy. Therefore, we investigated the incidence and prognosis effects of postoperative atrial fibrillation following septal myectomy in patients with hypertensive obstructive cardiomyopathy. Additionally, we investigated the relationship of estimated glomerular filtration rate and postoperative atrial fibrillation.METHODS: Data from 300 patients with hypertrophic obstructive cardiomy...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Yanhai Meng Shuiyun Wang Ping Liu Yanbo Zhang Bing Tang Changsheng Zhu Shengwei Wang Qiulan Yang Tao Lu Changrong Nie Source Type: research

A comparison of non-intubated video-assisted thoracic surgery with spontaneous ventilation and intubated video-assisted thoracic surgery: a meta-analysis based on 14 randomized controlled trials
J Thorac Dis. 2021 Mar;13(3):1624-1640. doi: 10.21037/jtd-20-3039.ABSTRACTBACKGROUND: Video-assisted thoracic surgery (VATS) generally involves endotracheal intubation under general anesthesia. However, inevitably, this may cause intubation-related complications and prolong the postoperative recovery process. Gradually, non-intubated video-assisted thoracic surgery (NIVATS) is increasingly being utilized. However, its safety and efficacy remain controversial.METHODS: Randomized controlled trials (RCTs) published up to August 2020 were selected from the Cochrane Library, Web of Science, PubMed, Embase, and ClinicalTrials.go...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Xi-Xuan Zhang Chun-Tao Song Zhen Gao Bin Zhou Hai-Bo Wang Qiang Gong Ben Li Qiang Guo He-Fei Li Source Type: research

Effect of OM-85 BV on reducing bronchiectasis exacerbation in Chinese patients: the iPROBE study
CONCLUSIONS: OM-85 BV did not demonstrate protection in decreasing pulmonary exacerbations of bronchiectasis in this trial performed in Chinese patients. It had good safety profile.PMID:33841955 | PMC:PMC8024857 | DOI:10.21037/jtd-20-1662 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Jinming Gao Lun Li Nan Jiang Ying Liao Lingfei Kong Yuanlin Song Jinfu Xu Jie Cao Yuping Li Chengli Que Roy A Pleasants Source Type: research

Prevalence of comorbidities in a surgical pectus excavatum population
CONCLUSIONS: The majority of patients undergoing pectus excavatum surgery have no comorbidities or previous medical conditions. It seems that this patient category is comparable to the background population in this regard and our findings do not support screening this patient category for associated conditions.PMID:33841956 | PMC:PMC8024824 | DOI:10.21037/jtd-20-3352 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Ara Shwan Media Thomas Decker Christensen Niels Katballe Hans Kristian Pilegaard Frank Vincenzo de Paoli Source Type: research

Molecular characterization of advanced non-small cell lung cancer patients by cfDNA analysis: experience from routine laboratory practice
J Thorac Dis. 2021 Mar;13(3):1658-1670. doi: 10.21037/jtd-20-3142.ABSTRACTBACKGROUND: Analysis of circulating free DNA (cfDNA) by the real-time PCR cobas® EGFR Mutation Test v2 (cobas® EGFR Test) is a diagnostic approach used in clinical practice for the characterization of advanced non-small cell lung cancer (NSCLC) patients. The test additionally outputs a semiquantitative index (SQI) which reflects the proportion of mutated versus wild-type copies of the EGFR gene in cfDNA with potential use as a biomarker. CfDNA concentration and cfDNA fragmentation pattern have also shown potential utility as biomarkers for ca...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Jos é Manuel González de Aledo-Castillo Ainara Arcocha Iv án Victoria Ana Isabel Martinez-Puchol Cristina S ánchez Pedro Jares Gabriel Felipe Rodr íguez N úria Viñolas Roxana Reyes Noem í Reguart Joan Ant ón Puig-Butillé Source Type: research

Minimally-invasive versus transcatheter aortic valve implantation: systematic review with meta-analysis of propensity-matched studies
This study directly compares and analyses the available evidence for early outcomes between these two AVR methods.METHODS: Electronic databases were searched from inception until August 2019 for studies comparing MiAVR to TAVI, according to predefined search criteria. Propensity-matched studies with sufficient data were included in a meta-analysis.RESULTS: Eight studies with 9,744 patients were included in the quantitative analysis. Analysis of risk-matched patients showed no difference in early mortality (RR 0.76, 95% CI, 0.37-1.54, P=0.44). MiAVR had a signal towards lower rate of postoperative stroke, although this did ...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Mathew P Doyle Kei Woldendorp Martin Ng Michael P Vallely Michael K Wilson Tristan D Yan Paul G Bannon Source Type: research

Prenatal and postnatal exposure to Bisphenol A and Asthma: a systemic review and meta-analysis
CONCLUSIONS: Prenatal and postnatal exposure to BPA was related to an increased risk of childhood asthma. However, only postnatal and early gestational exposure (at 16 weeks) to BPA could induce the risk of childhood wheeze, but not late gestational exposure (at 26 weeks).PMID:33841959 | PMC:PMC8024800 | DOI:10.21037/jtd-20-1550 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Mindan Wu Shuyi Wang Qingyu Weng Haixia Chen Jiaxin Shen Zhouyang Li Yanping Wu Yun Zhao Miao Li Yinfang Wu Shiyi Yang Qichuan Zhang Huahao Shen Source Type: research

Aspirin plus ticagrelor or clopidogrel on graft patency one year after coronary bypass grafting: a single-center, randomized, controlled trial
CONCLUSIONS: Either aspirin plus ticagrelor or aspirin plus clopidogrel can maintain a fairly high graft patency rate in the early phase after CABG, regardless of CYP2C19 genotypes.PMID:33841960 | PMC:PMC8024791 | DOI:10.21037/jtd-20-3407 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Yangfeng Tang Xinli Fan Boyao Zhang Jiajun Zhang Qin Xue Zhiyun Xu Lin Han Source Type: research

Predictors and long-term prognosis of left ventricular aneurysm in patients with acute anterior myocardial infarction treated with primary percutaneous coronary intervention in the contemporary era
J Thorac Dis. 2021 Mar;13(3):1706-1716. doi: 10.21037/jtd-20-3350.ABSTRACTBACKGROUND: Primary percutaneous coronary intervention (PCI) has been the standard reperfusion strategy for patients with acute myocardial infarction (AMI) in the contemporary era. Meanwhile, the incidence and prognosis of left ventricular aneurysm (LVA) in AMI patients remain ambiguous. The aim of the current study is to identify the predictor and long-term prognosis of LVA in patients with acute anterior myocardial infarction.METHODS: We prospectively enrolled 942 consecutive patients with acute anterior myocardial infarction who were treated by pr...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Jieyun You Liming Gao Yunli Shen Wei Guo Xingxu Wang Qing Wan Xiaoyan Wang Jian Wu Qi Zhang Source Type: research

Simultaneous bilateral thoracoscopic lobectomy for synchronous bilateral multiple primary lung cancer-single center experience
J Thorac Dis. 2021 Mar;13(3):1717-1727. doi: 10.21037/jtd-20-3325.ABSTRACTBACKGROUND: The aim of this study was to investigate the feasibility and safety of simultaneous bilateral thoracoscopic lobectomy and compare perioperative and late outcomes between simultaneous and staged bilateral thoracoscopic lobectomy.METHODS: Between January 2013 and December 2017, the medical records of patients who underwent bilateral thoracoscopic lobectomy for synchronous bilateral multiple primary lung cancer (SPLC) were reviewed retrospectively. Univariate analysis was used to examine the factors associated with morbidity. Survival was es...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Hui Zheng Qiao Peng Dong Xie Liang Duan Deping Zhao Gening Jiang Yuming Zhu Chang Chen Source Type: research

Serum creatinine as a predictor of mortality in patients readmitted to the intensive care unit after cardiac surgery: a retrospective cohort study in China
CONCLUSION: Renal function is significantly associated with the in-hospital mortality of patients readmitted to the ICU after cardiac surgery, as evidenced by the independent correlation of both creatinine and eGFR with in-hospital mortality.PMID:33841963 | PMC:PMC8024843 | DOI:10.21037/jtd-20-3205 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Jun Zhong Jian Gao Jing-Chao Luo Ji-Li Zheng Guo-Wei Tu Yan Xue Source Type: research

In-hospital outcome of primary PCI for patients with acute myocardial infarction and prior coronary artery bypass grafting
This study aims to analyze the in-hospital outcome of primary percutaneous coronary intervention (PCI) for patients with acute myocardial infarction (AMI) and prior coronary artery bypass grafting (CABG).METHODS: This was a retrospective study. From January 2011 to December 2018, the data of 78 consecutive patients (study group) with prior CABG, who received primary coronary angiography in the setting of ST-elevation myocardial infarction (STEMI) or non-ST-elevation myocardial infarction (NSTEMI), were screened. The study group was compared with another well-matched 78 patients without a history of CABG (control group). Th...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Yu Liu Le-Feng Wang Xin-Chun Yang Pi-Xiong Su Kui-Bao Li Hong-Shi Wang Mu-Lei Chen Li Xu Jiu-Chang Zhong Source Type: research

Time-dependence and comparison of regional and overall anthropometric features between Asian and Caucasian populations with obstructive sleep apnea: a cumulative meta-analysis
CONCLUSIONS: BMI, NC, WC and WHR are associated with OSA in both ethnic groups. Anthropometry for overall and regional obesity could facilitate differentiation of patients with OSA from individuals without OSA by ethnicity.PMID:33841965 | PMC:PMC8024799 | DOI:10.21037/jtd-20-1799 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Hua Qin Chongxiang Chen Nicolas Steenbergen Yang Cheng Thomas Penzel Source Type: research

Neoadjuvant pembrolizumab with chemotherapy for the treatment of stage IIB-IIIB resectable lung squamous cell carcinoma
CONCLUSIONS: The early outcomes of pembrolizumab with chemotherapy in the neoadjuvant setting as a novel treatment for resectable stage IIB-IIIB LUSC showed a high pCR rate that has not been seen previously, as well as a high R0 resection rate and a low toxicity profile. The long-term efficacy of this novel treatment and the validity of the present findings should be confirmed with longer follow-up and prospective comparative trials.PMID:33841966 | PMC:PMC8024839 | DOI:10.21037/jtd-21-103 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Dijian Shen Jiangfeng Wang Jie Wu Sheng Chen Jianqiang Li Jinshi Liu Qixun Chen Youhua Jiang Source Type: research

Enhanced expression of FGF19 predicts poor prognosis in patients with non-small cell lung cancer
J Thorac Dis. 2021 Mar;13(3):1769-1784. doi: 10.21037/jtd-21-126.ABSTRACTBACKGROUND: Lung cancer is one of the most common cancers and a leading cause of cancer-related death worldwide. Although many treatment options exist for lung cancer, some patients still suffer postoperative recurrence, and a consequent reduction of overall survival (OS). Our study aimed to investigate the correlation of FGF19 expression with the clinicopathological features and survival outcomes of non-small cell lung cancer (NSCLC) patients.METHODS: Bioinformatics analysis was conducted using the data from The Cancer Genome Atlas (TCGA) database to...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Jia Chen Jingjing Shao Aiguo Shen Xinghua Zhu Xunlei Zhang Hui Sun Sheng Wei Yang Ling Source Type: research

Identification of key immune-related genes and immune infiltration in atrial fibrillation with valvular heart disease based on bioinformatics analysis
CONCLUSIONS: The key immune-related genes and the differences in immune infiltration in LA tissues play an essential role in the occurrence and progression of AF-VHD.PMID:33841968 | PMC:PMC8024788 | DOI:10.21037/jtd-21-168 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Shuo Li Zhiyuan Jiang Xiaoying Chao Chenyang Jiang Guoqiang Zhong Source Type: research

Evaluation of different treatment strategies between right-sided and left-sided pneumonectomy for stage I-IIIA non-small cell lung cancer patients
This study aimed to assess the different survival outcomes of stage I-IIIA non-small cell lung cancer (NSCLC) patients who received right-sided and left-sided pneumonectomy, and to further develop the most appropriate treatment strategies.METHODS: We accessed data from the Surveillance, Epidemiology, and End Results database from the United States for the present study. An innovative propensity score matching analysis was used to minimize the variance between groups.RESULTS: For 2,683 patients who received pneumonectomy, cancer-specific survival [hazard ratio (HR) =0.863, 95% confidence interval (CI): 0.771 to 0.965, P=0.0...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Bo Jia Qiwen Zheng Jianjie Li Jun Zhao Meina Wu Tongtong An Yuyan Wang Minglei Zhuo Xue Yang Hanxiao Chen Yujia Chi Jingjing Wang Xiaoyu Zhai Yuling He Lingdong Kong Ziping Wang Source Type: research

Efficacy and safety of pemetrexed maintenance chemotherapy for advanced non-small cell lung cancer in a real-world setting
CONCLUSIONS: Pemetrexed maintenance chemotherapy can improve PFS in patients with advanced nonsquamous NSCLC with good tolerability.PMID:33841970 | PMC:PMC8024837 | DOI:10.21037/jtd-21-337 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Jianjie Li Yujia Chi Guang Cao Jun Zhao Tongtong An Meina Wu Yuyan Wang Minglei Zhuo Xue Yang Bo Jia Hanxiao Chen Jingjing Wang Xiaoyu Zhai Ziping Wang Source Type: research

A propensity-matched analysis of stereotactic body radiotherapy and sublobar resection for stage I non-small cell lung cancer in patients at high risk for lobectomy: the results in a Chinese population
CONCLUSIONS: Disease control and survival in the SBRT patients was equivalent to that seen in SLR patients with stage I NSCLC considered high-risk lobectomy candidates. SBRT could therefore be an alternative option to SLR in treating patients with a high operative risk.PMID:33841971 | PMC:PMC8024811 | DOI:10.21037/jtd-21-339 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Xiao-Shuai Yuan Wu-Cheng Chen Qing-Ren Lin Yuan-Jun Liu Yao-Yao Zhu Xiao-Jiang Sun Qiong-Ya Wu Jin-Shi Liu Ya-Ping Xu Source Type: research

Surgical management for unruptured sinus of Valsalva aneurysms: a narrative review of the literature
J Thorac Dis. 2021 Mar;13(3):1833-1850. doi: 10.21037/jtd-20-2682.ABSTRACTUnruptured sinus of Valsalva aneurysms (SVAs) are rare cardiac lesions that arise due to congenital or acquired etiologies. They could be asymptomatic or cause various clinical manifestations as a consequence of their mass effect on the coronary arteries, heart valves, and other adjacent structures. While the factors predicting SVA rupture are not fully understood, ruptured SVAs carry a high complication and mortality rate, highlighting the need for early recognition and management of unruptured SVAs. Imaging modalities such as echocardiography, comp...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Quynh Nguyen Dominique Vervoort Kevin Phan Jessica G Y Luc Source Type: research

Expression and clinical implications of estrogen receptors in thoracic malignancies: a narrative review
J Thorac Dis. 2021 Mar;13(3):1851-1863. doi: 10.21037/jtd-20-2277.ABSTRACTThoracic malignancies represent a significant global health burden with incidence and mortality increasing year by year. Thoracic cancer prognosis and treatment options depend on several factors, including the type and size of the tumor, its location, and the overall health status of patients. Gender represents an important prognostic variable in thoracic malignancies. One of the greatest biological differences between women and men is the presence of female sex hormones, and an increasing number of studies suggest that estrogens may play either a ca...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Giulia Pinton Beatrice Manzotti Cecilia Balzano Laura Moro Source Type: research

Coronary angiography utilization in the evaluation of a potential heart donor by age: a narrative review
J Thorac Dis. 2021 Mar;13(3):1864-1868. doi: 10.21037/jtd-20-2547.ABSTRACTHeart transplant is the gold standard treatment for patients with heart failure. The limitation to providing heart transplantation to patients suffering from end stage heart disease is the stable organ supply within the United States despite increasing demand. Transplant centers across the United States have begun to expand traditional cardiac donor selection metrics previously utilized. As a result, the use of extended criteria donors, such as older donors, those with longer ischemic times, and donors considered high risk has increased. Current guid...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Christine M Johnstad Amy G Fiedler Source Type: research

The predictive value of Holter monitoring in the risk of obstructive sleep apnea
In this study, by comparing Holter monitoring to polysomnography (PSG), we try to find out an operable way for clinicians to use Holter to predict OSA risk.METHODS: Patients (n=63) suspected of OSA underwent Holter monitoring with concurrent PSG at a sleep center. Respiration and heart rate variability (HRV) indices were calculated from the Holter and compared with PSG indices.RESULTS: The sensitivity of the Holter-derived respiratory waveform for OSA was 90.0%, and the specificity was 82.6%. The time domain indices including standard deviation of all NN intervals during 24 hours, mean of standard deviation of the averages...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Miaochan Lao Qiong Ou Cui'e Li Qian Wang Ping Yuan Yilu Cheng Source Type: research

Minimally invasive cardiac surgery-a Fad or the Future?
J Thorac Dis. 2021 Mar;13(3):1882-1885. doi: 10.21037/jtd-2020-mics-12.NO ABSTRACTPMID:33841976 | PMC:PMC8024829 | DOI:10.21037/jtd-2020-mics-12 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Jason M Ali Yasir Abu-Omar Source Type: research

Anesthesia for minimally invasive cardiac surgery
J Thorac Dis. 2021 Mar;13(3):1886-1898. doi: 10.21037/jtd-20-1804.ABSTRACTDue to its potential benefits and increased patient satisfaction minimal invasive cardiac surgery (MICS) is rapidly gaining in popularity. These procedures are not without challenges and require careful planning, pre-operative patient assessment and excellent intraoperative communication. Assessment of patient suitability for MICS by a multi-disciplinary team during pre-operative workup is desirable. MICS requires additional skills that many might not consider to be part of the standard cardiac anesthetic toolkit. Anesthetists involved in MICS need n...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Alexander White Chinmay Patvardhan Florian Falter Source Type: research

Endoscopic vein harvesting
J Thorac Dis. 2021 Mar;13(3):1899-1908. doi: 10.21037/jtd-20-1819.ABSTRACTCoronary artery bypass grafting is the most common cardiac surgical procedure performed worldwide and the long saphenous vein the most common conduit for this. When performed as an open vein harvest (OVH), the incision on each leg can be up to 85cm long, making it the longest incision of any routine procedure. This confers a high degree of morbidity to the procedure. Endoscopic vein harvest (EVH) methods were popularised over two decades ago, demonstrating significant benefits over OVH in terms of leg wound complications including surgical site infec...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Enoch Akowuah Daniel Burns Joseph Zacharias Bilal H Kirmani Source Type: research

From less invasive to minimal invasive extracorporeal circulation
J Thorac Dis. 2021 Mar;13(3):1909-1921. doi: 10.21037/jtd-20-1830.ABSTRACTDevelopment of minimally invasive cardiac surgery (MICS) served the purpose of performing surgery while avoiding the surgical stress triggered by a full median sternotomy. Minimizing surgical trauma is associated with improved cosmesis and enhanced recovery leading to reduced morbidity. However, it has to be primarily appreciated that the extracorporeal circulation (ECC) stands for the basis of nearly all MICS procedures. With some fundamental modification and advancement in perfusion techniques, the use of ECC has become the enabling technology for ...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Kyriakos Anastasiadis Polychronis Antonitsis Apostolos Deliopoulos Helena Argiriadou Source Type: research

Minimally invasive and robotic coronary artery bypass grafting-a 25-year review
J Thorac Dis. 2021 Mar;13(3):1922-1944. doi: 10.21037/jtd-20-1535.ABSTRACTDuring the mid-1990s cardiac surgery started exploring minimally invasive methods for coronary artery bypass grafting (CABG) and has over a 25-year period developed highly differentiated and less traumatic operations. Instead of the traditional sternotomy mini-incisions on the chest or ports are placed, surgery on the beating heart is applied, sophisticated remote access heart lung machine systems as well as videoscopic units are available, and robotic technology enables completely endoscopic approaches. This review describes these methods, reports o...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Johannes Bonatti Stephanie Wallner Ingo Crailsheim Martin Grabenw öger Bernhard Winkler Source Type: research

Minimally invasive aortic valve surgery
J Thorac Dis. 2021 Mar;13(3):1945-1959. doi: 10.21037/jtd-20-1968.ABSTRACTSince their introduction, it has been demonstrated that minimally invasive aortic valve replacement (MIAVR) approaches are safe and effective for the treatment of aortic valve diseases. To date, the main advantage of these approaches is represented by the reduced surgical trauma, with a subsequent reduced complication rate and faster recovery. This makes such approaches an appealing choice also for frail patients [obese, aged, chronic obstructive pulmonary disease (COPD)]. The standardization of the minimally invasive techniques, together with the im...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Lorenzo Di Bacco Antonio Miceli Mattia Glauber Source Type: research

Minimally invasive mitral valve surgery
J Thorac Dis. 2021 Mar;13(3):1960-1970. doi: 10.21037/jtd-20-2114.ABSTRACTThere is considerable interest and demand in the application of minimally invasive techniques in cardiac surgery driven by multiple factors including patient cosmesis and satisfaction, reduction of surgical trauma and the development of specialized instrumentation that allows these procedures to be performed safely. Minimally invasive mitral valve surgery (MIMVS) has been conducted for more than 25 years and has been shown to offer multiple benefits including better cosmetic results, enhanced post-operative recovery, improved patient satisfaction and...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Yasir Abu-Omar Ibrahim T Fazmin Jason M Ali Marc P Pelletier Source Type: research

Robotic mitral valve surgery: a review and tips for safely negotiating the learning curve
J Thorac Dis. 2021 Mar;13(3):1971-1981. doi: 10.21037/jtd-20-1790.ABSTRACTTotally endoscopic robotic mitral valve repair represents the least invasive surgical therapy for mitral valve disease. Comparative results for robotic mitral valve surgery against sternotomy are impressive, repeatedly demonstrating shorter hospital stay, faster return to normal activities, less morbidity and equivalent mortality and mid-term durability. We lack data comparing robotic approaches to totally endoscopic minimally invasive mitral valve surgery using 3D vision platforms. In this review, we explore the advantages and disadvantages of robot...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Caroline Toolan Kenneth Palmer Omar Al-Rawi Tim Ridgway Paul Modi Source Type: research

Minimally invasive tricuspid valve surgery
J Thorac Dis. 2021 Mar;13(3):1982-1992. doi: 10.21037/jtd-20-1331.ABSTRACTTricuspid valve disease carries a very unfavorable prognosis when medically treated. Despite that, surgical intervention is still underperformed for tricuspid valve disease due to the reported high morbidity and mortality from a sternotomy approach. This had led to a shift towards maximizing medical therapy for right ventricular failure and, as a result, a more significant delay in surgical referrals with surgical risks when patients are finally referred. Tricuspid valve patients usually have other co-morbidities resulting from their systemic venous ...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Abdelrahman Abdelbar Ayman Kenawy Joseph Zacharias Source Type: research

Minimally invasive resection of benign cardiac tumors
J Thorac Dis. 2021 Mar;13(3):1993-1999. doi: 10.21037/jtd-20-1201.ABSTRACTPrimary cardiac tumours for which surgical resection is the main stay of treatment are rare and present both diagnostic and management challenges. The majority of patients are asymptomatic and one third of those who have symptoms present with vague constitutional symptoms which further complicates the process of early diagnosis. The current state-of-the art multi-modality imaging, routine use of intra-operative transoesophageal echocardiogram (TOE) in most cardiac centres and the tremendous advances of endoscopic adjuncts greatly enhances both the di...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Ayman Kenawy Abdelrahman Abdelbar Joseph Zacharias Source Type: research

Insights from advancements and pathbreaking research on the minimally invasive treatment of atrial fibrillation
J Thorac Dis. 2021 Mar;13(3):2000-2009. doi: 10.21037/jtd-20-1876.ABSTRACTAtrial fibrillation (AF) remains the most common cardiac arrhythmia with increasing prevalence in developed and aging countries. Pharmacological antiarrhythmic therapy has low effectiveness and is limited by its toxicity. Developed in 1987 by James Cox surgical ablation of AF called MAZE procedure was very effective, but due to its invasiveness and complexity was not widely adopted. Landmark research done by Haissaguerre in 1998 initiated a new approach for treatment namely percutaneous catheter ablation, which remains a class I/A indication in sympt...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Anna Witkowska Piotr Suwalski Source Type: research

Minimally invasive ventricular assist device implantation
J Thorac Dis. 2021 Mar;13(3):2010-2017. doi: 10.21037/jtd-20-1492.ABSTRACTDurable mechanical circulatory support (MCS) systems are established therapy option in patients with end-stage heart failure, with increasing importance during the last years due to donor organ shortage. Left ventricular assist devices (LVADs) are traditionally implanted through median sternotomy (MS). However, improvement in the pump designs during the last years led to evolvement of new surgical approaches that aim to reduce the invasiveness of the procedure. Numerous reports and studies have shown the viability and possible advantages of less-inva...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Ameen Al-Naamani Florian Fahr Asim Khan Christian Bireta Michael Nozdrzykowski Stefan Feder Nikhil Deshmukh Manal Jubeh Sandra Eifert Khalil Jawad Uwe Schulz Michael A Borger Diyar Saeed Source Type: research

Specialist training in Europe: introduction to a special issue of the < em > Journal of Thoracic Disease < /em >
J Thorac Dis. 2021 Mar;13(3):2018-2020. doi: 10.21037/jtd.2019.12.28.NO ABSTRACTPMID:33841988 | PMC:PMC8024810 | DOI:10.21037/jtd.2019.12.28 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Gilbert Massard Daiana Stolz Source Type: research

Why do we need harmonization in thoracic surgery: a view from above by the European Union of Medical Specialists
J Thorac Dis. 2021 Mar;13(3):2021-2028. doi: 10.21037/jtd.2019.01.49.ABSTRACTFounded in 1958 the UEMS (Union Européenne des Médecins Spécialistes-European Union of Medical Specialists) has become the largest European Medical organization representing over 1.5 million specialists of 43 Specialties in 39 countries. The primary goal of UEMS is to defend the interests of Specialists in the broadest sense of the word. This includes promoting the highest quality of care, the highest standards of training, continuous professional development (CPD) and continuous medical education (CME). For the latter the Eur...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Toni Lerut Dirk Van Raemdonck Gilbert Massard Source Type: research

Harmonisation of respiratory medicine: the success story of European curriculum development
This article will describe the overall methodology and the projects developed over the years, detailing their objectives and target audiences. Moving forward, ERS strives to provide a structure for the continuing professional development of respiratory physicians.PMID:33841990 | PMC:PMC8024833 | DOI:10.21037/jtd.2019.02.40 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Daiana Stolz Nathalie Tabin Amy Farr Source Type: research

Methodology of curriculum development
J Thorac Dis. 2021 Mar;13(3):2035-2037. doi: 10.21037/jtd.2019.01.89.NO ABSTRACTPMID:33841991 | PMC:PMC8024819 | DOI:10.21037/jtd.2019.01.89 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Nathalie Tabin Carine Pannetier Daiana Stolz Source Type: research

Auditorium of the future: e learning platform
J Thorac Dis. 2021 Mar;13(3):2038-2043. doi: 10.21037/jtd.2019.12.69.ABSTRACTPrinciples of surgical training have not changed, but methods of training are evolving very fast. Online tools are being adopted in both knowledge and skills training for surgical residents. As a result, to evaluate the outcome of these tools, online assessment is also developing. Knowledge resources are very diverse ranging from lectures, webinars, surgical videos to three-dimensional planning and printing. Skills resources include virtual reality simulators, remote skills training and interdisciplinary teamwork. Assessment of E-learning tools ca...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Hasan F Batirel Jalal Assouad Harry Etienne Xavier Benoit D'Journo Source Type: research

Teaching non-technical skills: the patient centered approach
J Thorac Dis. 2021 Mar;13(3):2044-2053. doi: 10.21037/jtd.2019.01.48.ABSTRACTThe surgical setting is a highly complex environment where, in ideal conditions, everything should be under control to ensure a positive outcome. However, the existing complexity opens the possibility for multiple failures along the process and many of those failures are related to what is call the non-technical skills of the members of the team. We cannot eradicate human error, but we can try to avoid future mistakes in our daily practice introducing the awareness for providing a high-quality care in which patient safety is crucial. This paper pr...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Gianluca Casali Gareth Lock Nuria M Novoa Source Type: research

Utilization of a training portfolio in thoracic and cardiovascular surgery: the example of the French platform-EPIFORM
This report describes the implementation of a portfolio in the teaching and assessment of French trainees in Thoracic and Cardiovascular surgery, following an electronic logbook model, aiming to improve the training program. The French surgical course is a twelve semesters' curriculum divided in 3 parts, each part containing knowledge, technical skills and behaviors objectives to be validated, defined by the French College of Thoracic and Cardiovascular surgery. The competencies are marked in the logbook, following a declarative model where the surgical trainee fills every surgical procedure attended (all or part) if he/sh...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Alex Fourdrain Charles-Henri David Lucile Gust Gilbert Massard Source Type: research

Structured and evidence-based training of technical skills in respiratory medicine and thoracic surgery
We present a practical guide contributing to future educators' considerations on (I) problem identification and general needs assessment, (II) targeted needs assessment, (III) goals and objectives, (IV) educational strategies, (V) implementation, and finally (VI) evaluation and feedback.PMID:33841995 | PMC:PMC8024809 | DOI:10.21037/jtd.2019.02.39 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Pia Iben Pietersen Christian B Laursen Ren é Horsleben Petersen Lars Konge Source Type: research

How to prepare for academic leadership: scientific training curriculum
J Thorac Dis. 2021 Mar;13(3):2068-2074. doi: 10.21037/jtd.2019.06.49.ABSTRACTThoracic surgery has evolved into an independent discipline out of general surgery practice over the past decades. The development of the field of thoracic surgery was generated from surgeons being motivated to move this field forward by constant analysis and critical appraisal and review of current practice, as well as identification of new research approaches as the pool and generator of innovation. For this purpose, scientific skills are needed that are currently not covered during the surgical training. In the present overview, we will try to ...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Isabelle Opitz Thorsten Walles Source Type: research

Mobility during and after training: autobiography and advice to early career colleagues
J Thorac Dis. 2021 Mar;13(3):2075-2078. doi: 10.21037/jtd.2019.01.71.ABSTRACTMobility programs can be a valuable enhancement to medical formation and career, either during or after training as part of an internship or as a fellowship. In the case of surgery, the opportunity to visit departments who offer a broader range of operations than the home institution, learn new clinical and surgical techniques are unique possibilities to expand surgical and clinical daily routine practice but also to meet colleagues and exchange experiences for future collaboration and networking.PMID:33841997 | PMC:PMC8024808 | DOI:10.21037/jtd.2...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Carolina Torres Anna Elisabeth Frick Source Type: research

Erratum to the role of postoperative radiotherapy for thymomas: a multicentric retrospective evaluation from three Italian centers and review of the literature
J Thorac Dis. 2021 Mar;13(3):2079. doi: 10.21037/jtd-2021-04.ABSTRACT[This corrects the article DOI: 10.21037/jtd-2019-thym-09.].PMID:33841998 | PMC:PMC8024835 | DOI:10.21037/jtd-2021-04 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Editorial Office Source Type: research

Retraction: Computational fluid dynamics in the numerical simulation analysis of end-to-side anastomosis for coarctation of the aorta
J Thorac Dis. 2021 Mar;13(3):2080. doi: 10.21037/jtd-2021-14.ABSTRACT[This retracts the article DOI: 10.21037/jtd.2018.11.37.].PMID:33841999 | PMC:PMC8024844 | DOI:10.21037/jtd-2021-14 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Fang Yang Bo Zhai Li-Gong Hou Qian Zhang Jie Wang Source Type: research