Programmed death-ligand 1 expression discrepancy between primary tumor and metastatic lymph nodes in non-small cell lung cancer.
Authors: Kian W, Roisman LC, Wallach N, Levitas D, Yakobson A, Dudnik Y, Peled N, Rouvinov K PMID: 32944298 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Is it time to reconsider the need for bullectomy in the surgical management of primary spontaneous pneumothorax?
Authors: Ali JM, Aresu G PMID: 32944299 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Significance of topical diagnosis in extreme situations.
Authors: Klepikov I PMID: 32944300 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Objective analysis of postoperative air leaks can aid in decision-making, but does the use of digital drains really impact patient outcomes?
Authors: Joshi V, Dimarakis I PMID: 32944301 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Beyond standard care?-idiopathic pulmonary fibrosis patients' perception of care coordinators.
Authors: Hagmeyer L, Randerath W PMID: 32944302 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Lung cancer and obstructive lung disease in never smokers.
Authors: Yoneyama R, Saji H, Takeuchi S, Ikeda N PMID: 32944303 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Scoring tools to monitor risk of disease progression in patients with cystic fibrosis.
Authors: Donadio MVF, Vendrusculo FM, Pérez-Ruiz M PMID: 32944304 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Thoracoscopic resection of congenital pulmonary airway malformations: timing and technical aspects.
Authors: Macchini F PMID: 32944305 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Perioperative fluid balance and 30-day unplanned readmission after lung cancer surgery: a retrospective study.
This study aimed to determine whether perioperative FB status during and up to 24 hours after lung resection surgery is associated with the 30-day unplanned readmission rate. Methods: This retrospective cohort study examined adult patients aged 19 years or older who underwent lung cancer surgery at a single tertiary academic hospital between January 2005 and February 2018. Weight-based cumulative FB (%) was calculated during and up to 24 hours after surgery and was categorized as positive (≥5%), normal (0-5%), or negative (5%) during and up to 24 hours after surgery was associated with an increased 30-day unplanned ...
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Preliminary experimental outcomes of induced hypercapnia in treatment of obstinate singultus.
Conclusions: One of the definitive conditions for ceasing singultus is acute CO2 retention in the body, the target of which is around 60 mmHg of CO2 in venous blood. We believe that targeting acute hypercapnia can always stop singultus, although further neuroscientific investigation is necessary to reveal the physiological mechanism. PMID: 32944307 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Clinical features and surgical outcomes of type A intramural hematoma.
Conclusions: Our strategy had got low mortality and excellent mid-term survival in patients with type A IMH. Therefore, our strategy was suitable for the surgical repair of type A IMH in Chinese population. PMID: 32944308 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Is invasive mediastinal staging necessary in intermediate risk patients with negative PET/CT?
Conclusions: Invasive staging does not reduce the incidence of pN2. However, this finding could be biased because in our series cN1 patients were more often staged and cN1 has been detected as a risk factor for pN2. In addition patient better selection after invasive staging might have an impact on overall survival. To conclude, invasive mediastinal staging in intermediate risk patients for positive mediastinal nodes is justified. PMID: 32944309 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Determining the optimal puncture site of CT-guided transthoracic needle aspiration biopsy for the diagnosis of tuberculosis.
Authors: Zhou Z, Dong Y, Li C, Wang D, Lv Y, Lv P, Pang Y Abstract Background: The purpose of this study was to determine the optimal puncture site of computed tomography (CT)-guided transthoracic needle aspiration biopsy for the diagnosis of tuberculosis (TB) by the comparison of clinical and radiological characteristics of TB patients stratified to different histopathological results. Methods: We retrospectively analysed the data of clinically diagnosed TB patients with negative laboratory results between July 2016 and June 2018. Biopsy specimens were obtained from patients for Ziehl-Neelsen (Z-N) staining an...
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Reverse "L" surgical approach for the management of giant tumors of the cervicothoracic junction.
Conclusions: Applying reverse "L" surgical approach is safe, feasible, and effective for the resection of giant tumors of the cervicothoracic junction. PMID: 32944311 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Diameter and growth rate of the thoracic aorta-analysis based on serial computed tomography scans.
Authors: Chang HW, Kim SH, Hakim AR, Chung S, Kim DJ, Lee JH, Kim JS, Lim C, Park KH Abstract Background: Although there are studies on the growth of thoracic aorta in the general population, research based on serial computed tomography scan is rare. We investigated the influence of patient age and anthropometric variables on the size and growth rate of the thoracic aorta in the general hospital population. Methods: Data on 2,353 adults [2003-2014] who underwent ≥2 serial computed tomography examinations with at least a 6-year interval were analyzed. There were 1,444 men (61%), and the mean age was 58±...
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Comparison of metagenomic next-generation sequencing technology, culture and GeneXpert MTB/RIF assay in the diagnosis of tuberculosis.
In this study, we collected the results of both mNGS and culture of 70 specimens from suspected TB patients at the Shanghai Pulmonary Hospital of Tongji University. Results of GeneXpert MTB/RIF assay (Xpert) were obtained from 19 patients. We also assessed the diagnostic performance, relationship and consistency between mNGS, traditional culture method, and Xpert. Results: Overall, 36 of 70 suspected patients were finally diagnosed with TB. The sensitivity, specificity, positive predictive value, negative predictive value and the Youden index of mNGS in all clinical TB specimens were calculated as 66.7% (95% CI: 0.489-...
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Intermediate oncologic outcomes after uniportal video-assisted thoracoscopic thymectomy for early-stage thymoma.
Conclusions: Our findings suggest that uniportal VATS thymectomy for early-stage thymoma is feasible, and the intermediate-term oncologic outcomes are comparable to historic standards for open and multi-incision VATS thymectomy. However, additional follow-up is required to evaluate for long-term oncologic outcomes. PMID: 32944314 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Comparison of the progression-free survival between robot-assisted thymectomy and video-assisted thymectomy for thymic epithelial tumors: a propensity score matching study.
Conclusions: RATT has the superiorities over VATT on short-term outcomes due to enabling surgeons to operate in a stable and comfortable environment. Meanwhile, RATT yielded a longer PFS compared with VATT, although the difference was not significant. Therefore, RATT could be considered as a standard approach for the treatment of thymic epithelial tumors. PMID: 32944315 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Comparison of clinical characteristics and inflammatory cytokines between hypoxemic and non-hypoxemic human adenovirus 55 pneumonia.
Authors: Lim JU, Choi JY, Jeong HJ, Ko JH, Lee JE, Rhee CK Abstract Background: Human adenovirus (HAdV) can cause severe community-acquired pneumonia, but there are few studies on the associated cytokine patterns. The purpose of this study was to analyze the relationship between inflammatory cytokine and severity of adenovirus pneumonia. Methods: This was a prospective observational study. We evaluated pneumonia patients admitted to the Armed Forces Capital Hospital in Korea. On admission, blood samples were acquired from patients who showed signs of pneumonia. HAdV infection was diagnosed using Real-Q RV detec...
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Fatal toxic effects related to EGFR tyrosine kinase inhibitors based on 53 cohorts with 9,569 participants.
Conclusions: The overall incidence of fatal toxic effects related to EGFR-TKIs was 1.33%, and the major fatal cause was ILD, followed by pneumonia, respiratory failure and diarrhea. The susceptible factor of fatal toxic effects related to EGFR-TKIs was the Japanese group. This study provided a capability for clinicians to predict and detect high-risk populations of fatal toxic effects. PMID: 32944317 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Quantifying the learning curve of emergent total arch replacement in acute type A aortic dissection.
Conclusions: Although emergent total arch replacement for acute type A dissection is a complex scenario, surgeons well-trained in adult cardiac surgery are able to achieve acceptable results in their start-up period. PMID: 32944318 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

A simple and reliable method to preoperatively detect a common trunk of the left pulmonary vein.
Conclusions: We established a simple and reliable method of detecting a common trunk of the left PV in the axial view on chest CT that was routinely performed prior to lung cancer surgery. PMID: 32944319 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Extended sleeve-lobectomy for centrally located locally advanced non-small cell lung cancer is a feasible approach to avoid pneumonectomy.
Conclusions: ESL is a safe and effective procedure that should be considered a favorable alternative to PN whenever it may guarantee a complete resection. PMID: 32944320 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

The length of the left superior pulmonary vein stump after left upper lobectomy depends on its position to the left atrial appendage.
Conclusions: The anatomical relationship between the LSPV and LAA, identified on pre-operative CT images, was associated with the length of the LSPV stump after LUL. PMID: 32944321 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

del Nido cardioplegia in surgery for aortic root disease: a historically controlled study.
Conclusions: DNC is safe and effective for surgery for aortic root disease, not inferior to the CBC. PMID: 32944322 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Paravertebral block with modified catheter under surgeon's direct vision after video-assisted thoracoscopic lobectomy.
Authors: Xu Y, Li XK, Zhou H, Cong ZZ, Wu WJ, Qiang Y, Shen Y Abstract Background: Paravertebral block (PVB) conducted by epidural catheter is a prevalent pain management for patients undergoing video-assisted thoracoscopic surgery (VATS) lobectomy. The aim of this study was to assess the efficacy and safety of paravertebral block with a modified PVB (MPVB) catheter under surgeon's direct vision after video-assisted thoracoscopic lobectomy. Methods: Three hundred fifty-six patients undergoing VATS lobectomy were retrospectively reviewed and divided into two groups consecutively according to the catheter applied...
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Staged repair of chronic type A aortic dissection with small true lumen at the descending aorta.
Conclusions: The two-staged procedure for the repair of chronic type A dissection with small true lumen at the descending aorta is adaptable with low prevalence of mortality and complication. PMID: 32944324 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Seroradiologic prognostic evaluation of acute exacerbation in patients with idiopathic interstitial pneumonia: a retrospective observational study.
Conclusions: Combining the HRCT pattern and the ΔKL-6/ST-KL-6 value can improve our ability to predict the survival of AE-IIP patients. PMID: 32944325 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Virtual thoracoscopic imaging-assisted pleural marking of pulmonary nodules.
Conclusions: Our pleural marking, using a virtual thoracoscopic image, identified the tumor location with high accuracy, may help surgeon to confirm whether the palpated nodule is the target one. This new procedure can assist in the localization of the pulmonary nodule with ease of application, safety, and accuracy. PMID: 32944326 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

The value of preoperative spirometry testing for predicting postoperative risk in upper abdominal and thoracic surgery assessed using big-data analysis.
Authors: Park HJ, Kim SM, Kim HR, Ji W, Choi CM Abstract Background: Spirometry is used to evaluate postoperative outcomes in thoracic surgery. However, the clinical utility of spirometry for predicting postoperative complications has not been determined. We used big-data analysis to examine the relationship between pulmonary function tests and postoperative complications. Methods: We retrospectively analysed clinical data from 31,827 patients who underwent spirometry within the 3 months prior to their surgery between January 2000 and December 2014 at a single tertiary referral hospital. The data were extracted...
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Total cavopulmonary connection with a new restorative vascular graft: results at 2 years.
Conclusions: The new restorative conduit has been successfully used for the second step of the Fontan procedure as extracardiac total cavopulmonary connection. The results are promising because they suggest that complete transformation of a bioabsorbable polymer and replacement through endogenous tissue may represent a major advantage in the treatment of congenital heart disease patients. Further monitoring will allow to evaluate the long-term behavior of this new graft, in terms of clinical and hemodynamic performance, thrombogenicity and ability to grow. PMID: 32944328 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Evaluation of ultrasound-guided erector spinae plane block for postoperative management of video-assisted thoracoscopic surgery: a prospective, randomized, controlled clinical trial.
Authors: Shim JG, Ryu KH, Kim PO, Cho EA, Ahn JH, Yeon JE, Lee SH, Kang DY Abstract Background: Video-assisted thoracoscopic surgery (VATS) is a commonly performed minimally invasive procedure that has led to lower levels of pain, as well as procedure-related mortality and morbidity. However, VATS requires analgesia that blocks both visceral and somatic nerve fibers for more effective pain control. This randomized controlled trial evaluated the effect of erector spinae plane block (ESPB) in the postoperative analgesia management of patients undergoing VATS. Methods: We performed a prospective, randomized, singl...
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Efficacy and safety of high-dose budesonide/formoterol in patients with bronchiolitis obliterans syndrome after allogeneic hematopoietic stem cell transplant.
Conclusions: Our study failed to show superior effect of high-dose budesonide/formoterol (320/9 µg) compared with low-dose. However, high-dose budesonide/formoterol was safe and there was no lung function deterioration. PMID: 32944330 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Preoperative evaluation of the segmental artery by three-dimensional image reconstruction vs. thin-section multi-detector computed tomography.
Conclusions: Both 3D image reconstruction and thin-section MDCT provided precise preoperative information about SA. The 3D image reconstruction software "Exoview" could visualize SA for surgeons. However, the thin-section MDCT provided a better evaluation of small SA branches. PMID: 32944331 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

WW and C2 domain-containing protein-3 promoted EBSS-induced apoptosis through inhibiting autophagy in non-small cell lung cancer cells.
Conclusions: These results indicate that WWC3 promotes apoptosis and death of starved lung cancer cells, at least partly through autophagy. PMID: 32944332 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Distribution of pathogenic bacteria in lower respiratory tract infection in lung cancer patients after chemotherapy and analysis of integron resistance genes in respiratory tract isolates of uninfected patients.
Conclusions: Lung cancer patients after chemotherapy have a high resistance to commonly used antimicrobial drugs, so it is necessary to detect the resistance of pathogenic microorganisms in clinical practice. The strains carried by patients with lung cancer without pulmonary infection during chemotherapy can isolate type I integrons, suggesting that the spread of drug resistance at gene level should be closely detected. PMID: 32944333 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Utility of the sliding lung sign for the prediction of preoperative intrathoracic adhesions.
Conclusions: The ultrasound sliding lung sign could be used to predict severe intrathoracic adhesions before surgery. Preoperative confirmation of the ultrasound sliding lung sign is important for planning surgical approaches and implementing appropriate safety management. PMID: 32944334 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Prevalence of influenza and pneumococcal vaccination in chronic obstructive pulmonary disease patients in association with the occurrence of acute exacerbations.
Conclusions: We found association between influenza and pneumococcal vaccination and the reduced risk of hospitalization due to exacerbations in the ensuing year. The prevalence of vaccination is significantly below the optimal level. PMID: 32944335 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Association between reproductive lifespan and lung function among postmenopausal women.
This study aims to evaluate the association between RL and lung function among postmenopausal women. Methods: In the Korean National Health and Nutrition Examination Survey (2010-2015), an annual cross-sectional survey of a national representative sample of non-institutionalized Korean population, the postmenopausal women aged 40-64 years who underwent spirometry were included. Spirometry was performed according to the recommendations of the American Thoracic Society and European Respiratory Society, and RL (years) was calculated by subtracting the age at menarche from age at menopause. Results: Among 3,410 postmen...
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Gender effects on quality of life and symptom burden in patients with lung cancer: results from a prospective, cross-cultural, multi-center study.
Conclusions: This study adds to the literature in showing that the typical QoL gender difference effect (women doing worse than men) may not be generalizable across all patient samples. PMID: 32944337 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Efficient isolation and quantification of circulating tumor cells in non-small cell lung cancer patients using peptide-functionalized magnetic nanoparticles.
Conclusions: Highly efficient CTC isolation technique based on peptide-magnetic nanoparticles was firstly applied in NSCLC patients. Compared with the antibody-based the technique, the higher CTC detection rates (71.4%) in NSCLC patient blood samples were demonstrated for the patients in different stages, I-IV, especially in early stages. This indicates the feasibility of the clinical utility of this new technique in early stage screening, prognosis and therapy evaluation of NSCLC. PMID: 32944338 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

The mutation profiles of cell-free DNA in patients with oesophageal squamous cell carcinoma who were responsive and non-responsive to neoadjuvant chemotherapy.
Conclusions: The driver gene MMB and CNVs in plasma cfDNA may be potential biomarkers for predicting the response to neoadjuvant chemotherapy in patients with OSCC. PMID: 32944339 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

CT-guided blood tattoo for thoracoscopic excision of lung lesions in pediatric patients.
Conclusions: CT-guided blood tattoo is a safe option for localization of nonpleural-based lung nodules prior to thoracoscopic excision in pediatric patients. PMID: 32944340 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Conversion ratio of tacrolimus switching from intravenous infusion to oral administration after lung transplantation.
Authors: Yang C, Xi Y, Chen WY, Sang L, Liu DD, Zhang R, Chen SB, Zhang J, Pan JY, Xv YH, Nong LB, Li YM, Liu XQ Abstract Background: To investigate the conversion ratio of tacrolimus switching from intravenous infusion to oral administration in patients after lung transplantation. Methods: We retrospectively recruited patients received lung transplantation in the First Affiliated Hospital of Guangzhou Medical Hospital from January 2015 to June 2019. The blood concentration of tacrolimus administrated through intravenous infusion and oral administration were collected. The blood concentration, concentration/dos...
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Efficacy of standard chest compressions in patients with Nuss bars.
Conclusions: In our model, Nuss bars limited the ability to perform chest compressions due to increased force required to achieve a 5 cm compression. The greater the number of Nuss bars present the greater the force required. This may prevent effective CPR. Use of active abdominal compressions and decompressions should be studied further as an alternative resuscitation modality for patients after the Nuss procedure. PMID: 32944342 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Implementation of a pulmonary thromboembolism prophylaxis program in Chinese lung surgery patients: compliance and effectiveness.
Authors: Shen L, Li Y, Ding J, Yang J, Jiang G, Sihoe ADL Abstract Background: Most studies on prophylaxis against pulmonary embolism (PE) after lung surgery have come from the West. Whether such prophylactic programs can be successfully developed in China has not been fully studied. Methods: A prospective observational trial included 581 Chinese patients receiving lung resection surgery between August 8 and September 12 of 2017. The Caprini score was assessed on the first postoperative day (POD1). For PE prophylaxis, patients with a low score (0-4, n=55) received early ambulation, and those with a high score (...
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Predicting malignancy: subsolid nodules detected on LDCT in a surgical cohort of East Asian patients.
Authors: Wang YH, Chen CF, Lin YK, Chiang C, Tzao C, Yen Y Abstract Background: Due to widespread use of low-dose computed tomography (LDCT) screening, increasing number of patients are found to have subsolid nodules (SSNs). The management of SSNs is a clinical challenge and primarily depends on CT imaging. We seek to identify risk factors that may help clinicians determine an optimal course of management. Methods: We retrospectively reviewed the characteristics of 83 SSN lesions, including 48 pure ground-glass nodules and 35 part-solid nodules, collected from 83 patients who underwent surgical resection. R...
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

The impact of concordance with a lung cancer diagnosis pathway guideline on treatment access in patients with stage IV lung cancer.
This study assesses the impact of Cancer Care Ontario (CCO) Lung Cancer Diagnostic Pathway Guideline (LCDPG) concordance on access to treatment of stage IV lung cancer patients referred to the Diagnostic Assessment Program (DAP) at a Canadian tertiary cancer centre. Methods: This retrospective cohort study includes patients diagnosed with clinical stage IV lung cancer referred to the DAP at a Canadian tertiary cancer centre between November 1, 2015 and May 31, 2017. Referral concordance was determined based on CCO LCDPG. The primary outcome; time to treatment from initial healthcare presentation; was compared between t...
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

A multidisciplinary approach for the diagnosis of benign asbestos pleural effusion: a single-center experience.
Conclusions: BAPE is diagnosed by exclusion. A suspected diagnosis of BAPE with an asbestos exposure should be considered, especially with the presence of pleural plaques, and/or DPT, and rounded atelectasis. The MDT-based diagnostic approach may reduce misdiagnosis. PMID: 32944346 [PubMed] (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

The impact of age on the survival outcomes and risk of radiation pneumonitis in patients with unresectable locally advanced non-small cell lung cancer receiving chemoradiotherapy.
This study aimed to determine the impact of age on the survival outcomes and risk of radiation pneumonitis (RP) in patients with unresectable locally advanced NSCLC. Methods: The data of patients with unresectable locally advanced NSCLC who were treated with radiotherapy (RT), sequential chemoradiotherapy, or concurrent chemoradiotherapy between January, 2013, and December, 2017, in our institution were retrospectively reviewed and analyzed. Student's t-test and χ2 test were used to evaluate the differences between groups divided by optimal cutoff. Survival rates were calculated using the Kaplan-Meier method, and m...
Source: Journal of Thoracic Disease - September 20, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research