Wedge resection, segmentectomy, and lobectomy: oncologic outcomes based on extent of surgical resection for ≤2 cm stage IA non-small cell lung cancer
CONCLUSIONS: Patients with inferior performance status or lower baseline pulmonary function are more likely to receive wedge resection for clinical stage IA NSCLC ≤2 cm in size. For these small tumors, lobectomy, segmentectomy, and wedge resection provide comparable oncologic outcomes.PMID:38617767 | PMC:PMC11009583 | DOI:10.21037/jtd-23-1693 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Shaikha Al-Thani Abu Nasar Jonathan Villena-Vargas Sebron Harrison Benjamin Lee Jeffrey L Port Nasser Altorki Oliver S Chow Source Type: research
Recent progress in radioactive seed implantation brachytherapy of non-small cell lung cancer: a narrative review
CONCLUSIONS: This review demonstrates that RSI-BT can be therapeutic in the treatment of both early and advanced NSCLC with manageable complications. There have also been reports on the combination of RSI-BT with other therapies, but more research is needed on the combination of RSI-BT with them.PMID:38617768 | PMC:PMC11009575 | DOI:10.21037/jtd-23-1600 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Xinyu Wang Sen Tian Hui Shi Hao Qin Wei Zhang Yuchao Dong Chong Bai Source Type: research
Clinical use of macitentan in the treatment of connective tissue disease-associated pulmonary arterial hypertension
CONCLUSIONS: Exercise tolerance and cardiac function in patients with CTD-PAH were significantly improved after treatment with macitentan, which was well tolerated. Therefore, macitentan may be an effective and safe targeted drug for CTD-PAH.PMID:38617769 | PMC:PMC11009607 | DOI:10.21037/jtd-24-151 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Xiaohui Song Xiangrui Sheng Lei Ding Jian Wu Xin Chang Erye Zhou Jing Cao Tao Cheng Mingjun Wang Source Type: research
Comparison of safety and effectiveness of different sheaths in ablation of focal atrial tachycardia: a retrospective study
CONCLUSIONS: The application of Vizigo sheath can improve the long-term success rate of FAT and reduce the radiation exposure of patients and medical staff in our single-center limited sample study. More research may be needed in the future to confirm our findings.PMID:38617770 | PMC:PMC11009573 | DOI:10.21037/jtd-24-52 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Min Xie Dingming Liu Ruikun Jia Yixuan Bai Juan Chan Zhongyun Lin Paul Khairy Kaijun Cui Source Type: research
Effect of particulate matter on continuous positive airway pressure adherence in obstructive sleep apnea patients
CONCLUSIONS: There was no effect of particulate matter on CPAP adherence in OSA patients.PMID:38617771 | PMC:PMC11009577 | DOI:10.21037/jtd-23-1507 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Kanokkarn Sunkonkit Nantaporn Tiyapun Warawut Chaiwong Ratirat Worasuthaneewan Theerakorn Theerakittikul Source Type: research
Ectopic mediastinal thyroid tissue: an indelible imitator
J Thorac Dis. 2024 Mar 29;16(3):1745-1749. doi: 10.21037/jtd-24-200. Epub 2024 Mar 27.NO ABSTRACTPMID:38617772 | PMC:PMC11009603 | DOI:10.21037/jtd-24-200 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Tiffany Elizabeth Jakowczuk Shuyue Ren Source Type: research
Comparison of early postoperative pulmonary complications between two-lung ventilation with artificial pneumothorax and one-lung ventilation with bronchial blockade in patients undergoing minimally invasive esophagectomy: a retrospective propensity score-matched cohort study
CONCLUSIONS: Compared with OLV with bronchial blockade, TLV with CO2 pneumothorax did not reduce the incidence of early PPCs after MIE.PMID:38617773 | PMC:PMC11009580 | DOI:10.21037/jtd-23-1667 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Xiaoxi Li Ling Yu Jiaonan Yang Miao Fu Hongyu Tan Source Type: research
Indwelling pleural catheter infection and colonisation: a clinical practice review
J Thorac Dis. 2024 Mar 29;16(3):2196-2204. doi: 10.21037/jtd-23-1761. Epub 2024 Mar 27.ABSTRACTIndwelling pleural catheters (IPCs) are used in the management of malignant pleural effusions, but they can become infected in 5.7% of cases. This review aims to provide a summary of the development of IPC infections and their microbiology, diagnosis and management. IPC infections can be deep, involving the pleural space, or superficial. The former are of greater clinical concern. Deep infection is associated with biofilm formation on the IPC surface and require longer courses of antibiotic treatment. Mortality from infections is...
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Dheeraj K Sethi Mark A Webber Eleanor K Mishra Source Type: research
Efficacy and safety analysis of immune checkpoint inhibitor rechallenge therapy in locally advanced and advanced non-small cell lung cancer: a retrospective study
CONCLUSIONS: ICI rechallenge therapy beyond disease progression did not improve clinical outcomes in patients with NSCLC, but no new safety signals emerged. However, patients with favorable response to initial ICIs treatment still showed significant efficacy of subsequent ICI rechallenge therapy.PMID:38617775 | PMC:PMC11009570 | DOI:10.21037/jtd-23-1767 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Xiaoqi Yan Luqing Zhao Fei Wu Bo Shen Guoren Zhou Jifeng Feng Chao Yue Jingni Zhu Shaorong Yu Source Type: research
Molecular characteristics and multivariate survival analysis of 43 patients with locally advanced or metastatic esophageal squamous cell carcinoma
CONCLUSIONS: NOTCH1, CBLB and TSC2 alterations were found to be potential indicators of poor prognosis in patients with ESCC. TMB was also positively correlated with the OS of ESCC patients, providing valuable insights for their treatment strategies.PMID:38617776 | PMC:PMC11009591 | DOI:10.21037/jtd-23-1601 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Xia Zhou Wuan Bao Xiang Zhu Di Wang Pengfei Zeng Guojie Xia Minyan Xing Yanyan Zhan Junrong Yan Minchi Yuan Qiang Zhao Source Type: research
Comparisons of short-term outcomes between robot-assisted, video-assisted, and open esophagectomy for resectable esophageal cancer after neoadjuvant treatment: a retrospective study
CONCLUSIONS: Compared to VAMIE, no clear benefit exists for RAE in the treatment of resectable EC after neoadjuvant therapy. OE resulted in a longer hospital stay. Although the rate of successful right RLN node removal was higher with RAE, the clinical relevance for this is yet unclear.PMID:38617777 | PMC:PMC11009584 | DOI:10.21037/jtd-24-75 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Ziheng Wu Jiacong Liu Lichen Zhang Muhu Tang Wenbo Shu Berend J van der Wilk Christopher J Anker Zhehao He Luming Wang Wang Lv Linhai Zhu Jian Hu Source Type: research
The role and mechanism of PDZ binding kinase in hypobaric and hypoxic acute lung injury
CONCLUSIONS: Overexpression of PBK inhibits the expression of p53 and activates SIRT1-PINK1 axis mediated mitochondrial autophagy to alleviate HHALI.PMID:38617778 | PMC:PMC11009593 | DOI:10.21037/jtd-24-188 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Linao Sun Haoran Yue Hao Fang Runze Li Shicong Li Jianyao Wang Pengjie Tu Fei Meng Wang Yan Jinxia Zhang Elena Bignami Kyeongman Jeon Biniam Kidane Peng Zhang Source Type: research
Incidental detection of ground glass nodules and primary lung cancer in patients with breast cancer: prevalence and long-term follow-up on chest computed tomography
CONCLUSIONS: Persistent GGNs in breast cancer patients with high-risk factors should be adequately monitored for early detection and treatment of lung cancer.PMID:38617779 | PMC:PMC11009589 | DOI:10.21037/jtd-23-1605 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Hye Sun Ryu Han Na Lee Jung Im Kim Jung Kyu Ryu Yu Jin Lim Source Type: research
The usefulness of the open surgical technique of sternocostal elevation for asymmetric pectus excavatum: a retrospective study
CONCLUSIONS: SCE is considered a highly useful surgical method for asymmetric PE.PMID:38617780 | PMC:PMC11009599 | DOI:10.21037/jtd-23-1824 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Tomoki Nishida Hiroshi Iida Kenshiro Ohmura Ryuta Fukai Source Type: research
Impact of lymph node dissection on the efficacy of immune checkpoint inhibitors in patients with postoperative recurrence of non-small cell lung cancer
CONCLUSIONS: IPTW-adjusted analysis indicated no difference in prognosis between patients with postoperative recurrence and those with advanced unresectable lung cancer. However, in patients with postoperative recurrence, the extent of LND was a significant predictor of ICI-PFS. These findings suggest that systematic LND may reduce the efficacy of ICI, indicating that preoperative ICI administration may be warranted.PMID:38617781 | PMC:PMC11009588 | DOI:10.21037/jtd-23-1806 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Yohei Kawaguchi Nanako Nishioka Taiyo Nakamura Kentaro Imai Takuya Aoki Naohiro Kajiwara Norihiko Ikeda Source Type: research
