Prognostic implication of Vasoactive Inotropic Score in adult patients with cardiogenic shock on veno-arterial extracorporeal membrane oxygenation
CONCLUSIONS: Firstly, higher maximum level of VIS within the first 6 hours before ECMO initiation independently predicted poorer clinical outcomes in patients supported with ECMO for CS. Secondly, VIS exceeding 20 was significantly associated with increased risks of in-hospital mortality and 30-day mortality. Thirdly, when categorized by the cause of CS, a high VIS exhibited good predictive ability in patients with acute myocardial infarction, heart failure, and acute myocarditis.PMID:38505065 | PMC:PMC10944791 | DOI:10.21037/jtd-23-823 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Yao Hu Liangshan Wang Feng Yang Xiaomeng Wang Shuai Zhang Xing Hao Hong Wang Xiaotong Hou Source Type: research
Promotion of non-small cell lung cancer tumor growth by < em > FHL2 < /em > via inducing angiogenesis and vascular permeability
CONCLUSIONS: Our study revealed the role of FHL2 in NSCLC and the mechanism by which FHL2 promotes NSCLC tumorigenesis, providing novel insights into targeted therapy for NSCLC.PMID:38505066 | PMC:PMC10944754 | DOI:10.21037/jtd-23-1975 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Tengfei Chen Jun Chen Qiuyun Chen Zhipan Liang Liuying Pan Jun Zhao Xiaowei She Source Type: research
Fascial structure of the anterior mediastinum: the surgical figure of the sternopericardial ligament and the role of affixing the thymus to the pericardium
CONCLUSIONS: Our observation of the SPL showed differences from classical descriptions. The SPL is a sagittal fibrous collection showing a unique figure. Part of the SPL is thickened behind the thymus, anchoring the thymus to the pericardium in the midline. The SPL is part of the bottom of Grodinsky's Space 3 in the thorax. The SPL is visible in radiologic images, such as the anterior junction line on a plain chest radiograph.PMID:38505067 | PMC:PMC10944790 | DOI:10.21037/jtd-23-1602 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Kozo Nakanishi Hidenori Goto Source Type: research
Bioinformatics analysis of the prognostic role of alternative splicing data in lung adenocarcinoma
CONCLUSIONS: This study screened the ASE related to the prognosis of LUAD patients, and provided a theoretical basis for further study of the correlation between ASE and the prognosis of LUAD patients. It has provided new ideas for developing new biomarkers and therapeutic targets for LUAD patients.PMID:38505068 | PMC:PMC10944774 | DOI:10.21037/jtd-24-6 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Lingling Zhao Shuting He Ziwei Liu Zhibin Song Xiaochun Hou Ling Gai Source Type: research
The role of computed tomography prior to transcatheter aortic valve implantation: preprocedural planning and simultaneous coronary artery assessment
J Thorac Dis. 2024 Feb 29;16(2):833-838. doi: 10.21037/jtd-23-1384. Epub 2024 Feb 2.NO ABSTRACTPMID:38505069 | PMC:PMC10944746 | DOI:10.21037/jtd-23-1384 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Matthias Renker Grigorios Korosoglou Source Type: research
Modified surgical incision suturing technique in uniportal video-assisted thoracoscopic pulmonary resection
CONCLUSIONS: Our modified suture method reduces the chance of infection and splitting and the severity of postoperative incision scar formation, promoting early healing. It can be safely and effectively applied to the incision suture of uniportal thoracoscopic pulmonary resection, enhancing the rapid postoperative recovery of patients.PMID:38505070 | PMC:PMC10944763 | DOI:10.21037/jtd-23-1968 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Liuying Pan Tengfei Chen Zhipan Liang Piergiorgio Solli Benedetta Bedetti Kyung Soo Kim Xiaowei She Source Type: research
The effect of infectious diseases on lung transplantation in Japan
J Thorac Dis. 2024 Feb 29;16(2):1632-1644. doi: 10.21037/jtd-22-1884. Epub 2024 Feb 27.ABSTRACTLung transplantation in Japan is an increasingly accessible treatment option for end-stage lung disease; however, the lack of donor organs is a persisting challenge. Five- and 10-year survival rates of lung transplant recipients in Japan are comparable, if not superior, to international standards. The outcomes of lung transplantation in Japan are likely affected by multiple factors. Infectious disease complications are a significant burden to transplant recipients and account for approximately 30% of recipient mortality in Japan,...
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Satoshi Kitaura Koh Okamoto Source Type: research
Unraveling the intricacies of neoadjuvant immune checkpoint blockade in esophageal squamous cell carcinoma: a comprehensive single-cell perspective
J Thorac Dis. 2024 Feb 29;16(2):826-828. doi: 10.21037/jtd-23-1771. Epub 2024 Feb 20.NO ABSTRACTPMID:38505072 | PMC:PMC10944718 | DOI:10.21037/jtd-23-1771 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Gengyi Zou Junaid Anwar Melissa P Pizzi Ahmed Abdelhakeem Source Type: research
Surgical-decision making in the setting of unsuspected N2 disease: a cost-effectiveness analysis
CONCLUSIONS: Treatment of stage IIIa lung cancer requires the input of a multidisciplinary team who must consider cost, quality of life, and overall survival. As new treatments are developed, further analyses should be performed to determine optimal therapy.PMID:38505073 | PMC:PMC10944766 | DOI:10.21037/jtd-23-1538 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Brian Mitzman Thomas K Varghese Wallace L Akerley Richard E Nelson Source Type: research
Differential response to roflumilast in patients with chronic obstructive pulmonary disease: real-world evidence
CONCLUSIONS: The benefit of roflumilast in moderate-to-severe exacerbations was estimated to be greater in specific subgroups of patients with COPD. Personalised approaches to roflumilast based on clinical phenotypes would be effective for COPD.PMID:38505074 | PMC:PMC10944795 | DOI:10.21037/jtd-23-1129 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Hyun Woo Lee Jiyu Sun Hyo-Jin Lee Jung-Kyu Lee Tae Yeon Park Eun Young Heo Chin Kook Rhee Deog Kyeom Kim Source Type: research
Cerebral protection in acute type A aortic dissection surgery: a systematic review and meta-analysis
CONCLUSIONS: This study demonstrated that the ACP and RCP are both safe and acceptable techniques to use in emergent settings. The uACP technique is equivalent to bACP in terms of PND and mortality, however, uACP is preferred over bACP in terms of TND.PMID:38505075 | PMC:PMC10944792 | DOI:10.21037/jtd-23-1039 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Mehran Rahimi Hadi Sahrai Ali Norouzi Mohammadreza Taban-Sadeghi Ahmadali Khalili Sina Hamzehzadeh Reza Ali Akbari Khoei Hossein Hosseinifard Ralf Martz Sulague Jacques Kpodonu Source Type: research
Anti-titin antibodies in a cohort of myasthenia gravis patients
CONCLUSIONS: The presence of anti-titin antibodies appears to correlate with underlying thymoma in early-onset MG cases and with generalized MG in late-onset cases. Prospective studies are needed to further study this association.PMID:38505076 | PMC:PMC10944723 | DOI:10.21037/jtd-23-94 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Jo ão Moura Ana Paula Sousa Raquel Sam ões Paula Carneiro Esmeralda Neves Ana Martins Silva Ernestina Santos Source Type: research
Improvement of idiopathic pulmonary fibrosis through a combination of < em > Astragalus < /em > radix and < em > Angelica sinensis < /em > radix via mammalian target of rapamycin signaling pathway-induced autophagy in rat
CONCLUSIONS: The combination of AR and AS protects against IPF by inducing autophagy via inhibiting the mTOR signaling pathway. The synergistic action of AR and AS is superior to that of either AR or AS alone.PMID:38505077 | PMC:PMC10944740 | DOI:10.21037/jtd-24-28 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Chao Sun Huaman Liu Baihong Chi Jia Han Yasuhiko Koga Kamyar Afshar Xue Liu Source Type: research
Transcatheter valve-in-valve implantation treatment with the J-valve system for tricuspid bioprosthesis deterioration: a report of two cases
CONCLUSIONS: The ViV technique with J-valve is feasible and effective in treating tricuspid bioprosthetic SVD in high-risk patients, avoiding cardiopulmonary bypass and conventional thoracotomy injury.PMID:38505078 | PMC:PMC10944779 | DOI:10.21037/jtd-23-1961 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Kaisheng Wu Jinglun Shen Xu Meng Shengxun Wang Christophe Dubois Rodrigo Bagur Shuai Zheng Fei Meng Haibo Zhang Source Type: research
Anatomical distribution and clinical significance of translobar bronchi, arteries, and veins hidden in the interlobar fissure
CONCLUSIONS: Translobar bronchovascular structures exhibited a high incidence and were more commonly present in IIFs. Surgeons should pay increased attention to these structures to prevent accidental injuries during anatomical pulmonary resection.PMID:38505079 | PMC:PMC10944793 | DOI:10.21037/jtd-23-1534 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Wenzheng Xu Zhihua Li Zhicheng He Chuan Gao Shusheng Zhu Weibing Wu Liang Chen Source Type: research
