The chest X-ray score baseline in predicting continuous oxygen therapy failure in low-risk aged patients after thoracic surgery
CONCLUSIONS: The RALE score predict the risk of COT failure in elderly, low-risk thoracic patients better than the Brixia score. This simple, cheap, and noninvasive method helps evaluate postoperative lung damage, monitor treatment response, and provide early warning for oxygen therapy escalation. Further studies are required to confirm the validity and applicability of this model in different settings and populations.PMID:38617782 | PMC:PMC11009605 | DOI:10.21037/jtd-23-1786 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Tongxin Li Weina Li Fengxi Chen Qianfeng Xu Gaoli Du Yong Fu Lihui Yuan Sha Zhang Wei Wu Ping He Mei Xia Source Type: research
Patients with idiopathic pulmonary fibrosis and refractory cough have traction bronchiectasis and distorted airway architecture: a retrospective case review study
The objective of this study was to investigate the clinical features of IPF patients with refractory cough and to clarify mechanisms for cough in these patients. We retrospectively reviewed the files of patients with the diagnosis of IPF at Kanazawa University Hospital and compared the clinical features of IPF patients with refractory cough with the clinical features of IPF patients without refractory cough. Among a total of 23 patients with IPF, 10 patients (43.5%) had chronic cough. Of the ten patients, seven patients had concomitant conditions that could lead to cough. Of these seven patients, the cough of four patients...
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Kenta Yamamura Johsuke Hara Satoshi Watanabe Takafumi Kobayashi Kazumasa Kase Yoshihiro Takeda Nanao Terada Hayato Koba Yuichi Tambo Noriyuki Ohkura Miki Abo Seiji Yano Source Type: research
Perioperative intravenous lidocaine in thoracoscopic surgery for improved postoperative pain control: a randomized, placebo-controlled, double-blind, superiority trial
CONCLUSIONS: Our results suggest that perioperative intravenous lidocaine administration reduces pain scores after VATS. The beneficial clinical effects are limited. Nevertheless, intravenous lidocaine may be helpful as part of a multimodal analgesia protocol or with patients in whom the use of other analgesics is contraindicated.TRIAL REGISTRATION: ClinicalTrials.gov NCT03677817.PMID:38617784 | PMC:PMC11009578 | DOI:10.21037/jtd-23-1438 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Aljaz Hojski Daniel Bolliger Makhmudbek Mallaev Sandrine Dackam Nikolay Tsvetkov Mark Wiese Tobias Schneider Andreas Lampart Didier Lardinois Source Type: research
Biofunctional study on chemoresistance in esophageal squamous carcinoma cells induced by missense mutation of < em > NOTCH1 p.E450K < /em >
CONCLUSIONS: The NOTCH1 p.E450K point mutation causes chemotherapy resistance in KYSE140 and KYSE450 ESCC cells. Cell functional experiments showed that the NOTCH1 p.E450K point mutation enhanced the proliferation, migration and invasion abilities of KYSE140 and KYSE450 cells and increased the number of cells in S phase.PMID:38617785 | PMC:PMC11009606 | DOI:10.21037/jtd-23-1880 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Keting Li Wentao Hao Jiwei Wu Xianben Liu Wenqun Xing Yan Zheng Source Type: research
Beyond diagnosis: a narrative review of the evolving therapeutic role of medical thoracoscopy in the management of pleural diseases
CONCLUSIONS: MT is an effective procedure for treating the clinical entities presented in this document; it must be carried out in selected patients, managed in centers with high procedural expertise. Further evidence is needed to assess the optimal indications and appropriate patients' profiles for therapeutic MT. The endpoints of length of hospital stay, surgical referral, complications and mortality will have to be considered in future studies to validate it as a therapeutic intervention to be applied globally.PMID:38617786 | PMC:PMC11009601 | DOI:10.21037/jtd-23-1745 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Alberto Fantin Nadia Castaldo Michelangelo Schwartzbaum Palou Giovanni Viterale Ernesto Crisafulli Giulia Sartori Filippo Patrucco Paolo Vailati Giuseppe Morana Federico Mei Lina Zuccatosta Vincenzo Patruno Source Type: research
Choice of anesthesia technique is associated with earlier hospital discharge and reduced costs after transcatheter transfemoral aortic valve implantation
CONCLUSIONS: Advancements in TAVI technologies, conscious sedation and a collaborative, multidisciplinary team approach reduces overall length of hospital stay and procedure costs.PMID:38617787 | PMC:PMC11009576 | DOI:10.21037/jtd-23-1739 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Carla Luzzi David Orlov Karen Foley Eric Horlick Mark Osten Robert James Cusimano George Djaiani Source Type: research
Effects of no mask, a surgical mask and a fabric buff on peripheral oxygenation saturation during moderate intensity exercise: a randomised cross-over study
CONCLUSIONS: SM and BM caused a mild but sustained reduction in SpO2 at commencement of exercise, which did not worsen throughout short (<30 min) moderate intensity exercise. Level of perception was similar, suggesting healthy people can wear masks during moderate exercise and activities of daily living.PMID:38617788 | PMC:PMC11009602 | DOI:10.21037/jtd-23-1178 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Dina Christa Janse van Rensburg Audrey Jansen van Rensburg Tanita Botha Kirsty Elliott Dimakatso Ramagole Lervasen Pillay Shona Hendricks Devlin Eyden Claire Arnott David James Stevens Source Type: research
Recommended approaches for screening and early detection of lung cancer in the Middle East and Africa (MEA) region: a consensus statement
CONCLUSIONS: There is a great need for large-scale screening programs, preferably integrated with tobacco-control programs and awareness programs for physicians and patients, which may facilitate higher adherence to lung cancer screening and improve survival outcomes.PMID:38617789 | PMC:PMC11009596 | DOI:10.21037/jtd-23-1568 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Ahmed Allehebi Ameen Al-Omair Bassam Mahboub Coenraad F Koegelenberg Mohsen Mokhtar Ashraf Mokhtar Madkour Khaled Al-Asad Ugur Selek Humaid O Al-Shamsi Source Type: research
Triglyceride-glucose index and triglyceride to high-density lipoprotein cholesterol ratio predict the prognosis in patients with type B aortic dissection receiving thoracic endovascular aortic repair
CONCLUSIONS: Elevated baseline TG/HDL-c ratio and TG/HDL-c ≥4.11 were significantly related to a higher risk of 1-year all-cause mortality among TBAD patients undergoing TEVAR. At the same time, the low TG/HDL-c ratio was also independently associated with 1-year all-cause mortality. Special attention should be paid to TBAD patients with a higher or an overly low TG/HDL-c ratio.PMID:38617790 | PMC:PMC11009597 | DOI:10.21037/jtd-23-1411 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Kaiwen Zhao Jinzhu Niu Hongqiao Zhu Rong Zhao Yudong Sun Shuangshuang Li Zaiping Jing Jian Zhou Source Type: research
The value of high-risk clinicopathologic features for chemotherapy in stage I non-small cell lung cancer: a propensity score-matched study
CONCLUSIONS: The presence of VPI was the dominant predictor and the examination of an insufficient number of LNs was the secondary indicator, and a high histologic grade was a potential indicator of the need to administer chemotherapy in the treatment of stage I NSCLC.PMID:38617791 | PMC:PMC11009572 | DOI:10.21037/jtd-24-305 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Kun Luan Alfredo Addeo Raja M Flores Nobuhiko Seki Ao Liu Source Type: research
Investigating the multitarget pharmacological mechanism of < em > Rhodiola wallichiana < /em > var. < em > cholaensis < /em > acting on angina pectoris using combined network pharmacology and molecular docking
CONCLUSIONS: The results of this study preliminarily identify the potential targets and signaling pathways of RW in AP therapy and lay a promising foundation for further experimental studies and clinical trials.PMID:38505080 | PMC:PMC10944760 | DOI:10.21037/jtd-23-1891 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Haitao Zhang Xudong Zhuang Zhixiong Li Xinrui Wang Source Type: research
The evolving role of transcatheter aortic valve implantation computed tomography in coronary artery assessment: a deeper dive into efficiency, challenges, and future perspectives
J Thorac Dis. 2024 Feb 29;16(2):829-832. doi: 10.21037/jtd-23-1520. Epub 2024 Feb 19.NO ABSTRACTPMID:38505081 | PMC:PMC10944751 | DOI:10.21037/jtd-23-1520 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: David C Rotzinger Guillaume Fahrni Source Type: research
Effects of case volume on short- and long-term outcomes following cadaveric lung transplantation in Japan
CONCLUSIONS: Case volume did not have effects on short- or long-term outcomes following LT in Japan, while there were large variations in long-term outcomes among the LV centers compared to those of the HV centers.PMID:38505082 | PMC:PMC10944781 | DOI:10.21037/jtd-23-90 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Masayuki Chida Takashi Inoue Takahiro Nakajima Yoshinori Okada Hisashi Oishi Jun Nakajima Masaaki Sato Ichiro Yoshino Hidemi Suzuki Daisuke Nakajima Yasushi Shintani Takashi Kanou Shinichi Toyooka Kentaroh Miyoshi Takeshi Shiraishi Toshihiko Sato Keitaro Source Type: research
Histopathologic fate of resected pulmonary pure ground glass nodule: a systematic review and meta-analysis
CONCLUSIONS: The portion of IA in cases of pure GGN is significantly larger that expected. More than half of them owned invasiveness components if MIA and IA were combined. Furthermore, there were quite number of lesions with aggressive histologic patterns other than the lepidic subtype. Therefore, further attempts are necessary to differentiate advanced histologic subtype among radiologically favorable pure GGN.PMID:38505083 | PMC:PMC10944737 | DOI:10.21037/jtd-23-1089 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Wongi Woo Du-Young Kang Yoon Jin Cha Vincent Kipkorir Seung Hwan Song Duk Hwan Moon Jae Il Shin Sungsoo Lee Source Type: research
High flow nasal oxygen < em > vs. < /em > conventional oxygen therapy over respiratory oxygenation index after esophagectomy: an observational study
CONCLUSIONS: HFNC improved the ROX index after esophagectomy through significant respiratory rate reduction. This tool should be considered for early respiratory support after extubation in this category of patients, not only as a rescue therapy for ARF, but also to optimize early postoperative respiratory function. Whether this will improve patients' outcomes requires further large randomized controlled trials.PMID:38505084 | PMC:PMC10944724 | DOI:10.21037/jtd-23-1176 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Cristian Deana Massimo Vecchiato Francesco Bellocchio Annarita Tullio Antonio Martino Antonio Ziccarelli Vincenzo Patruno Marika Pascolo Flavio Bassi Marta Pontoni Paola Raimondi Lorenzo Cereser Luigi Vetrugno Roberto Petri Alessandro Uzzau Source Type: research
