Cerebral protection in acute type A aortic dissection surgery: a systematic review and meta-analysis
CONCLUSIONS: This study demonstrated that the ACP and RCP are both safe and acceptable techniques to use in emergent settings. The uACP technique is equivalent to bACP in terms of PND and mortality, however, uACP is preferred over bACP in terms of TND.PMID:38505075 | PMC:PMC10944792 | DOI:10.21037/jtd-23-1039 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Mehran Rahimi Hadi Sahrai Ali Norouzi Mohammadreza Taban-Sadeghi Ahmadali Khalili Sina Hamzehzadeh Reza Ali Akbari Khoei Hossein Hosseinifard Ralf Martz Sulague Jacques Kpodonu Source Type: research

Anti-titin antibodies in a cohort of myasthenia gravis patients
CONCLUSIONS: The presence of anti-titin antibodies appears to correlate with underlying thymoma in early-onset MG cases and with generalized MG in late-onset cases. Prospective studies are needed to further study this association.PMID:38505076 | PMC:PMC10944723 | DOI:10.21037/jtd-23-94 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Jo ão Moura Ana Paula Sousa Raquel Sam ões Paula Carneiro Esmeralda Neves Ana Martins Silva Ernestina Santos Source Type: research

Improvement of idiopathic pulmonary fibrosis through a combination of < em > Astragalus < /em > radix and < em > Angelica sinensis < /em > radix via mammalian target of rapamycin signaling pathway-induced autophagy in rat
CONCLUSIONS: The combination of AR and AS protects against IPF by inducing autophagy via inhibiting the mTOR signaling pathway. The synergistic action of AR and AS is superior to that of either AR or AS alone.PMID:38505077 | PMC:PMC10944740 | DOI:10.21037/jtd-24-28 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Chao Sun Huaman Liu Baihong Chi Jia Han Yasuhiko Koga Kamyar Afshar Xue Liu Source Type: research

Transcatheter valve-in-valve implantation treatment with the J-valve system for tricuspid bioprosthesis deterioration: a report of two cases
CONCLUSIONS: The ViV technique with J-valve is feasible and effective in treating tricuspid bioprosthetic SVD in high-risk patients, avoiding cardiopulmonary bypass and conventional thoracotomy injury.PMID:38505078 | PMC:PMC10944779 | DOI:10.21037/jtd-23-1961 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Kaisheng Wu Jinglun Shen Xu Meng Shengxun Wang Christophe Dubois Rodrigo Bagur Shuai Zheng Fei Meng Haibo Zhang Source Type: research

Anatomical distribution and clinical significance of translobar bronchi, arteries, and veins hidden in the interlobar fissure
CONCLUSIONS: Translobar bronchovascular structures exhibited a high incidence and were more commonly present in IIFs. Surgeons should pay increased attention to these structures to prevent accidental injuries during anatomical pulmonary resection.PMID:38505079 | PMC:PMC10944793 | DOI:10.21037/jtd-23-1534 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Wenzheng Xu Zhihua Li Zhicheng He Chuan Gao Shusheng Zhu Weibing Wu Liang Chen Source Type: research

Investigating the multitarget pharmacological mechanism of < em > Rhodiola wallichiana < /em > var. < em > cholaensis < /em > acting on angina pectoris using combined network pharmacology and molecular docking
CONCLUSIONS: The results of this study preliminarily identify the potential targets and signaling pathways of RW in AP therapy and lay a promising foundation for further experimental studies and clinical trials.PMID:38505080 | PMC:PMC10944760 | DOI:10.21037/jtd-23-1891 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Haitao Zhang Xudong Zhuang Zhixiong Li Xinrui Wang Source Type: research

The evolving role of transcatheter aortic valve implantation computed tomography in coronary artery assessment: a deeper dive into efficiency, challenges, and future perspectives
J Thorac Dis. 2024 Feb 29;16(2):829-832. doi: 10.21037/jtd-23-1520. Epub 2024 Feb 19.NO ABSTRACTPMID:38505081 | PMC:PMC10944751 | DOI:10.21037/jtd-23-1520 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: David C Rotzinger Guillaume Fahrni Source Type: research

Effects of case volume on short- and long-term outcomes following cadaveric lung transplantation in Japan
CONCLUSIONS: Case volume did not have effects on short- or long-term outcomes following LT in Japan, while there were large variations in long-term outcomes among the LV centers compared to those of the HV centers.PMID:38505082 | PMC:PMC10944781 | DOI:10.21037/jtd-23-90 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Masayuki Chida Takashi Inoue Takahiro Nakajima Yoshinori Okada Hisashi Oishi Jun Nakajima Masaaki Sato Ichiro Yoshino Hidemi Suzuki Daisuke Nakajima Yasushi Shintani Takashi Kanou Shinichi Toyooka Kentaroh Miyoshi Takeshi Shiraishi Toshihiko Sato Keitaro Source Type: research

Histopathologic fate of resected pulmonary pure ground glass nodule: a systematic review and meta-analysis
CONCLUSIONS: The portion of IA in cases of pure GGN is significantly larger that expected. More than half of them owned invasiveness components if MIA and IA were combined. Furthermore, there were quite number of lesions with aggressive histologic patterns other than the lepidic subtype. Therefore, further attempts are necessary to differentiate advanced histologic subtype among radiologically favorable pure GGN.PMID:38505083 | PMC:PMC10944737 | DOI:10.21037/jtd-23-1089 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Wongi Woo Du-Young Kang Yoon Jin Cha Vincent Kipkorir Seung Hwan Song Duk Hwan Moon Jae Il Shin Sungsoo Lee Source Type: research

High flow nasal oxygen < em > vs. < /em > conventional oxygen therapy over respiratory oxygenation index after esophagectomy: an observational study
CONCLUSIONS: HFNC improved the ROX index after esophagectomy through significant respiratory rate reduction. This tool should be considered for early respiratory support after extubation in this category of patients, not only as a rescue therapy for ARF, but also to optimize early postoperative respiratory function. Whether this will improve patients' outcomes requires further large randomized controlled trials.PMID:38505084 | PMC:PMC10944724 | DOI:10.21037/jtd-23-1176 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Cristian Deana Massimo Vecchiato Francesco Bellocchio Annarita Tullio Antonio Martino Antonio Ziccarelli Vincenzo Patruno Marika Pascolo Flavio Bassi Marta Pontoni Paola Raimondi Lorenzo Cereser Luigi Vetrugno Roberto Petri Alessandro Uzzau Source Type: research

Identification of prognostic biomarkers of smoking-related lung cancer
CONCLUSIONS: Three genes BPIFA1, SLPI and SCGB3A1, were identified as being associated with smokers with lung cancer, with SCGB3A1 showing a close correlation with patient prognosis. These findings provide potential new targets for the treatment of lung cancer. Certainly, this study needs to more investigate the mechanism of these genes regulation.PMID:38505085 | PMC:PMC10944783 | DOI:10.21037/jtd-23-1890 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Chen Liang Wei Pan Zhijun Zhou Xiaomin Liu Source Type: research

A narrative review of the controversy on the risk of mycobacterial infections with immune checkpoint inhibitor use: does Goldilocks have the answer?
CONCLUSIONS: Studies are needed to test the hypothesis that ICIs may either protect or predispose to mycobacterial infections, depending on the baseline host immune status. Prospective studies are required of patients on ICIs that control for potential confounders as anecdotal case reports are insufficient to provide a causal link. Murine studies with ICIs are also required to corroborate or refute studies of mice with genetic disruption of an immune checkpoint.PMID:38505086 | PMC:PMC10944775 | DOI:10.21037/jtd-23-1395 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Akshara Vaddi Holly J Hulsebus Emily L O'Neill Vijaya Knight Edward D Chan Source Type: research

Mebendazole induces apoptosis and inhibits migration via the reactive oxygen species-mediated STAT3 signaling downregulation in non-small cell lung cancer
CONCLUSIONS: In summary, MBZ inhibited NSCLC cell viability and migration by inducing cell apoptosis via the ROS-JAK2-STAT3 signaling pathway. These data provide a theoretical basis for the use of MBZ in treating NSCLC.PMID:38505087 | PMC:PMC10944755 | DOI:10.21037/jtd-23-1978 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Zhipan Liang Qiuyun Chen Liuying Pan Xiaowei She Tengfei Chen Source Type: research

Predicting postoperative lung function using ventilation SPECT/CT in patients with lung cancer
CONCLUSIONS: Ventilation SPECT/CT was comparable to perfusion SPECT/CT in predicting postoperative lung function.PMID:38505088 | PMC:PMC10944722 | DOI:10.21037/jtd-23-1563 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Yong Ho Jeong Hyun Lee Hyo Jun Jang Dong Won Park Yun Young Choi Soo Jin Lee Source Type: research

Impact of family history of cancer on development of lung cancer among the Korean population: a prospective cohort study using KoGES data
J Thorac Dis. 2024 Feb 29;16(2):1741-1744. doi: 10.21037/jtd-23-1077. Epub 2024 Feb 27.NO ABSTRACTPMID:38505089 | PMC:PMC10944757 | DOI:10.21037/jtd-23-1077 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - March 20, 2024 Category: Respiratory Medicine Authors: Sang Hyuk Kim Hyun Lee Bo-Guen Kim Sang-Heon Kim Jang Won Sohn Ho Joo Yoon Dong Won Park Source Type: research