The global impact of SARS-CoV-2 variant BA.2.86: a comprehensive analysis with the latest developments and transmission trends - an epidemiological study
CONCLUSIONS: The SARS-CoV-2, novel variant BA.2.86, spread over six continents and 89 countries and affected 19,532 people worldwide. The disease is more prevalent in the United Kingdom, United States of America, and European countries. The detection of the disease in multiple continents and countries suggests some degree of transmissibility. Global health authorities need to rethink their policies and implement strict strategies to eradicate emerging variants and minimize the global disease burden.PMID:38639533 | DOI:10.26355/eurrev_202404_35928 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 19, 2024 Category: Drugs & Pharmacology Authors: S A Meo A S Meo D M Halepoto Source Type: research
Pharmacokinetics of Edoxaban 15 âmg in Very Elderly Patients with Nonvalvular Atrial Fibrillation: A Subanalysis of the ELDERCARE-AF Study
CONCLUSION: PK data support edoxaban 15 mg once daily for very elderly NVAF patients with high bleeding risk, with caution for patients with SRI and/or low body weight.PMID:38641335 | DOI:10.1055/s-0044-1785511 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - April 19, 2024 Category: Hematology Authors: Takeshi Yamashita Yoshiyuki Igawa Masayuki Fukuzawa Takuya Hayashi Stefanie Hennig Ken Okumura Source Type: research
Comparative Analysis of Clinical Outcomes: Posterior Cervical Endoscopic Discectomy versus Fenestration Laminectomy Discectomy for Cervical Disc Herniation
CONCLUSION: PCED showed favorable long-term clinical efficacy in the treatment of CDH, with excellent recovery and high safety. Compared to FLD, PCED resulted in reduced intraoperative blood loss, shorter incision length, and faster recovery. It also led to improved pain scores, functional outcomes, and quality of life measures. The absence of postoperative complications further supports the use of PCED as an effective treatment option for CDH.PMID:38639610 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 19, 2024 Category: Complementary Medicine Authors: Minhong Zhou Linxia Wang Xixi Xu Lijuan Wang Peifang Wang Source Type: research
Changes in psychopharmacotherapy for patients with schizophrenia in a psychiatric institution in Japan: A 12-year prescription survey pre- and post-introduction of clozapine
Asian J Psychiatr. 2024 Apr 9;96:104047. doi: 10.1016/j.ajp.2024.104047. Online ahead of print.ABSTRACTPsychopharmacotherapy for patients with schizophrenia in Japan has a long history of polypharmacy, which is rare worldwide but remains a critical problem. One reason for this is that clozapine was not available in Japan until 2009. We aimed to investigate the changes in psychopharmacotherapy in patients with schizophrenia over 12 years pre- and post-introduction of clozapine to clarify how psychopharmacotherapy for patients with schizophrenia has changed with the introduction of clozapine. We retrospectively collected dat...
Source: Asian Journal of Psychiatry - April 19, 2024 Category: Psychiatry Authors: Kohei Kitagawa Shusuke Uekusa Yuki Hanai Itsuki Kimura Masaru Tsukahara Azusa Kagawa Kenji Sasaoka Yui Sakishiro Ayaka Miyake Yuki Watanabe Daiki Baba Masafumi Kodama Yoshiki Kishi Norihito Yamada Takashi Yoshio Kazuhiro Matsuo Source Type: research
Isolation and genetic characterization of multiple genotypes of both H5 and H7 avian influenza viruses from environmental water in the Izumi plain, Kagoshima prefecture, Japan during the 2021/22 winter season
This study underscores the importance of monitoring both HPAIVs and LPAIVs to understand avian influenza virus ecology in migratory waterfowl populations.PMID:38640701 | DOI:10.1016/j.cimid.2024.102182 (Source: Comparative immunology, microbiology and infectious diseases.)
Source: Comparative immunology, microbiology and infectious diseases. - April 19, 2024 Category: Allergy & Immunology Authors: Kosuke Okuya Mana Esaki Kaori Tokorozaki Taichi Hasegawa Makoto Ozawa Source Type: research
Reliability of the DI-60 Digital Image Analyzer for Detecting Platelet Clumping and Obtaining Accurate Platelet Counts
Ann Lab Med. 2024 Apr 19. doi: 10.3343/alm.2024.0003. Online ahead of print.ABSTRACTPseudothrombocytopenia caused by platelet clumping (PC) can lead to unnecessary platelet transfusions or underdiagnosis of hematologic neoplasms. To overcome these limitations, we assessed the capacity of the Sysmex DI-60 digital morphology analyzer (Sysmex, Kobe, Japan) for detecting PC and determining an accurate platelet count in the presence of PC. For this purpose, 135 samples with or without PC (groups Y and N, respectively) were processed by an examiner (a hematologic specialist) using both the Sysmex XN-9000 and DI-60 analyzers. Alt...
Source: Annals of Laboratory Medicine - April 19, 2024 Category: Laboratory Medicine Authors: Suhyeon Woo Bohyun Kim Nam Hun Heo Min-Sun Kim Young Ahn Yoon Young-Jin Choi Source Type: research
Comparative Analysis of Clinical Outcomes: Posterior Cervical Endoscopic Discectomy versus Fenestration Laminectomy Discectomy for Cervical Disc Herniation
CONCLUSION: PCED showed favorable long-term clinical efficacy in the treatment of CDH, with excellent recovery and high safety. Compared to FLD, PCED resulted in reduced intraoperative blood loss, shorter incision length, and faster recovery. It also led to improved pain scores, functional outcomes, and quality of life measures. The absence of postoperative complications further supports the use of PCED as an effective treatment option for CDH.PMID:38639610 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 19, 2024 Category: Complementary Medicine Authors: Minhong Zhou Linxia Wang Xixi Xu Lijuan Wang Peifang Wang Source Type: research
Medical database analysis of the association between kidney function and achievement of glycemic control in older Japanese adults with type â2 diabetes who started with oral antidiabetic drugs
ConclusionsIn older Japanese adults with type â2 diabetes, those with a lower estimated glomerular filtration rate were more likely to achieve hemoglobin A1c of<7.0%. To safely manage blood glucose levels in older adults with chronic kidney disease, physicians should remain vigilant about the risk of iatrogenic hypoglycemia. (Source: Journal of Diabetes Investigation)
Source: Journal of Diabetes Investigation - April 19, 2024 Category: Endocrinology Authors: Ryo Suzuki,
Kiyoyasu Kazumori,
Tatsuya Usui,
Masahiko Shinohara Tags: Original Article Source Type: research
Prevalence and perceptions of flavour capsule cigarettes among adults who smoke in Brazil, Japan, Republic of Korea, Malaysia and Mexico: findings from the ITC surveys
Conclusion
Our study documented the high prevalence of FCCs in some countries, pointing to the need to develop and implement regulatory strategies to control these attractive products. (Source: BMJ Open)
Source: BMJ Open - April 19, 2024 Category: General Medicine Authors: Kyriakos, C. N., Erinoso, O., Driezen, P., Thrasher, J. F., Katanoda, K., Quah, A. C. K., Tabuchi, T., Perez, C. d. A., Seo, H. G., Kim, S. Y., Nordin, A. S. A., Hairi, F. M., Fong, G. T., Filippidis, F. T. Tags: Open access, Smoking and tobacco Source Type: research
Short sleep duration and smoking initiation in university students: a retrospective cohort study
ConclusionThis study clarified that university students with short sleep duration were vulnerable to smoking initiation. (Source: Sleep and Breathing)
Source: Sleep and Breathing - April 19, 2024 Category: Respiratory Medicine Source Type: research
Factors associated with smoking behaviour changes during the COVID-19 pandemic in Japan: a 6-month follow-up study
Conclusion
During the pandemic, dual cigarette and HTP use increased smoking intensity, whereas HTP-only use was associated with quitting but fear of COVID-19 and not having a home smoking ban made it harder to quit. (Source: Tobacco Control)
Source: Tobacco Control - April 19, 2024 Category: Respiratory Medicine Authors: Yamamoto, T., Abbas, H., Kanai, M., Yokoyama, T., Tabuchi, T. Tags: COVID-19 Original research Source Type: research
Projecting the impact of implementation of WHO MPOWER measures on smoking prevalence and mortality in Japan
Conclusions
To bring forward the elimination of tobacco smoking and substantially reduce smoking-related deaths, the government of Japan should fulfil its commitment to the FCTC and adopt stringent tobacco control measures delineated by MPOWER and beyond. (Source: Tobacco Control)
Source: Tobacco Control - April 19, 2024 Category: Respiratory Medicine Authors: Yang, S. L., Togawa, K., Gilmour, S., Leon, M. E., Soerjomataram, I., Katanoda, K. Tags: Open access Original research Source Type: research
Japan Tobacco corporate social responsibility activities misleadingly claim to advance Sustainable Development Goals
The 2030 Agenda for Sustainable Development, adopted by United Nations Member States in 2015, is a collective plan of action to achieve the agreed 17 Sustainable Development Goals (SDGs) via 169 targets. SDG 3 aims to ensure healthy lives and promote well-being for the entire population of all age groups.1 One of the measures to achieve this goal is strengthening the implementation of the WHO Framework Convention on Tobacco Control (WHO FCTC) in all countries (Target 3.a). Implementing the WHO FCTC and other best tobacco control measures is essential to meet Target 3.4: a one-third reduction in premature mortality from non...
Source: Tobacco Control - April 19, 2024 Category: Respiratory Medicine Authors: Hirano, T. Tags: Open access Ad watch Source Type: research
Synergistic effect of independent risk factors for post-endoscopic retrograde cholangiopancreatography pancreatitis: a multicenter retrospective study in Japan
CONCLUSIONS: As the number of risk factors for PEP increases, the risk of PEP may not be additive; however, it may multiply. Thus, aggressive prophylaxis for PEP is strongly recommended in patients with multiple risk factors.PMID:38632965 | DOI:10.5946/ce.2023.203 (Source: Clinical Endoscopy)
Source: Clinical Endoscopy - April 18, 2024 Category: Gastroenterology Authors: Hirokazu Saito Yoshihiro Kadono Takashi Shono Kentaro Kamikawa Atsushi Urata Jiro Nasu Masayoshi Uehara Ikuo Matsushita Tatsuyuki Kakuma Shunpei Hashigo Shuji Tada Source Type: research
The Causal Relationship between Angina Pectoris and Gout Based on Two Sample Mendelian Randomization
CONCLUSIONS: This MR study found a clear causal relationship between angina pectoris and gout, which increases the risk of angina pectoris.PMID:38633818 | PMC:PMC11022507 | DOI:10.1155/2024/4564596 (Source: Pain Research and Management)
Source: Pain Research and Management - April 18, 2024 Category: Anesthesiology Authors: Jian Xiong Yuxin Sun Hui Huang Yu Liu Fayang Ling Yin Wei Qianhua Zheng Wenchuan Qi Fanrong Liang Source Type: research
