Efficacy and Safety of a Stimulator Using Low-Intensity Pulsed Ultrasound Combined with Transcutaneous Electrical Nerve Stimulation in Patients with Painful Knee Osteoarthritis.
Conclusion: The effects of a stimulator using LIPUS with TENS on pain relief and functional improvement were not superior to the only TENS therapy. Cartilage regeneration, which was expected as an additional benefit of LIPUS, was also not significantly evident. Therefore, further investigation is warranted to determine whether the combination therapy is beneficial. This trial is registered with KCT0003883. PMID: 31316682 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - July 19, 2019 Category: Anesthesiology Authors: Kim ED, Won YH, Park SH, Seo JH, Kim DS, Ko MH, Kim GW Tags: Pain Res Manag Source Type: research

The Relationship between Infant Colic and Migraine as well as Tension-Type Headache: A Meta-Analysis.
Conclusion: This meta-analysis indicated that migraine was associated with increased incidence of infantile colic history, but TTH incidence was not relevant with the incidence of infantile colic history. PMID: 31316683 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - July 19, 2019 Category: Anesthesiology Authors: Zhang D, Zhang Y, Sang Y, Zheng N, Liu X Tags: Pain Res Manag Source Type: research

A Retrospective Case Series of a Novel Spinal Cord Stimulator Trial Technique with Less Displacement and Migration of the Trial Leads.
Conclusion: This case series was able to demonstrate that our described novel spinal cord stimulator trial lead placement and dressing technique can decrease the incidence of lead displacement and migration, thus improving trial success. PMID: 31281554 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - July 11, 2019 Category: Anesthesiology Authors: Shaparin N, Gritsenko K, Agrawal P, Kim S, Wahezi S, Gitkind A, Hascalovici J, Vydyanathan A, Bernstein J, Dizdarevic A, Mehta N, Kaufman A Tags: Pain Res Manag Source Type: research

Personality and Personality Disorders in Medication-Overuse Headache: A Controlled Study by SWAP-200.
Conclusion: Although MOH, SUD, and PD populations have been evaluated in multiple sites with different levels of expertise, the study supported the presence of a specific constellation of personality in MOH patients including obsessive (perfectionist) and dysphoric characteristics, as well as good enough psychological resources. No similarities to drug-addicted and personality-disordered patients were found. Practitioners' careful understanding of the personality characteristics of MOH patients may be useful to provide a road map for the implementation of more effective treatment strategies and intervention programs. ...
Source: Pain Research and Management - July 11, 2019 Category: Anesthesiology Authors: Galli F, Tanzilli A, Simonelli A, Tassorelli C, Sances G, Parolin M, Cristofalo P, Gualco I, Lingiardi V Tags: Pain Res Manag Source Type: research

P2Y6 Receptor-Mediated Spinal Microglial Activation in Neuropathic Pain.
Conclusions: These findings indicated the crucial role of the P2Y6 receptor in modulating the microglial and inflammatory responses in the process of NP in vivo. Results from this study would provide insights into targeting the P2Y6 receptor to treat NP in the near future. PMID: 31281556 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - July 11, 2019 Category: Anesthesiology Authors: Bian J, Zhang Y, Liu Y, Li Q, Tang HB, Liu Q Tags: Pain Res Manag Source Type: research

Juvenile Fibromyalgia and Headache Comorbidity in Children and Adolescents: A Literature Review.
Abstract Juvenile fibromyalgia (JFM) is a chronic pain syndrome with onset in developmental age, characterized by widespread musculoskeletal pain associated with other neurological or nonneurological symptoms. Headache is one of the most frequent comorbid conditions with JFM, but this association is still poorly studied in the juvenile population. The literature review was conducted searching through PubMed, Scopus, and Web of Science with a combination of the following free-text terms: "fibromyalgia," "juvenile fibromyalgia," "headache," "primary headache," "migraine,&...
Source: Pain Research and Management - July 11, 2019 Category: Anesthesiology Authors: Matera E, Palumbi R, Peschechera A, Petruzzelli MG, Sciruicchio V, de Tommaso M, Margari L Tags: Pain Res Manag Source Type: research

Effect of Deep Slow Breathing on Pain-Related Variables in Osteoarthritis.
This study evaluated the effect of a six-week deep slow breathing (DSB) program on pain, physical function, and heart rate variability (HRV) in subjects with lower extremity joint pain. Twenty subjects were assigned into training (n = 10) and control (n = 10) groups. The training group participated in a six-week DSB program consisting of weekly training sessions and at-home breathing exercises. DSB exercises focused on prolonging the exhalation and the pause following exhalation. The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) was used to assess pain and physical funct...
Source: Pain Research and Management - July 11, 2019 Category: Anesthesiology Authors: Larsen KL, Brilla LR, McLaughlin WL, Li Y Tags: Pain Res Manag Source Type: research

Psychological Aspects and Quality of Life in Chronic Pain.
PMID: 31281559 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - July 11, 2019 Category: Anesthesiology Authors: Zis P, Varrassi G, Vadalouka A, Paladini A Tags: Pain Res Manag Source Type: research

Effects of Mobilization Time on Occurrence of New Fractures after Vertebroplasty.
Conclusion: We came to the conclusion that mobilization time (hours) was not a risk factor in the development of new fractures. In addition, there is no relationship between mobilization time and localization of new fractures. PMID: 31281560 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - July 11, 2019 Category: Anesthesiology Authors: Akpolat AO, Karaca S Tags: Pain Res Manag Source Type: research

Quality of Life in Painful Peripheral Neuropathies: A Systematic Review.
Conclusion: The findings demonstrate that QoL is impaired in painful PN and should not be neglected in clinical practice. Patients' pain management and subsequent impact on QoL should routinely be assessed and monitored. PMID: 31249636 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - July 1, 2019 Category: Anesthesiology Authors: Girach A, Julian TH, Varrassi G, Paladini A, Vadalouka A, Zis P Tags: Pain Res Manag Source Type: research

Nonclosure of the Peritoneum during Appendectomy May Cause Less Postoperative Pain: A Randomized, Double-Blind Study.
Conclusion: Nonclosure of the peritoneum seems to shorten the duration of surgery without increasing complications during open appendectomy. Postoperative pain and life quality measures were not affected by nonclosure of the peritoneum. This trial is registered with NCT02803463. PMID: 31249637 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - July 1, 2019 Category: Anesthesiology Authors: Bektasoglu HK, Hasbahceci M, Yigman S, Yardimci E, Kunduz E, Malya FU Tags: Pain Res Manag Source Type: research

Can We Trust the Literature on Risk Factors and Triggers for Low Back Pain? A Systematic Review of a Sample of Contemporary Literature.
Conclusion: Trustworthy information regarding RFs and triggers of LBP is rare in the current literature. Future research needs to use precise definitions of LBP (onset of the "disease" vs. episodes) and nominate the timing of the associated factors in relation to the types of LBP as these are two critical factors when studying causes of LBP. PMID: 31214272 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - June 21, 2019 Category: Anesthesiology Authors: Ardakani EM, Leboeuf-Yde C, Walker BF Tags: Pain Res Manag Source Type: research

Differences in Pain Intensity of Tumors Spread to the Anterior versus Anterolateral/Lateral Portions of the Vertebral Body Based on CT Scans.
In conclusion, patients with tumor spread to the anterolateral/lateral portion of vertebrae bodies based on CT scan diagnosis experienced severe cancer pain. These patients needed strong opioids or palliative spinal irradiation for pain relief. PMID: 31214273 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - June 21, 2019 Category: Anesthesiology Authors: Hsu HC, Liao TY, Ro LS, Juan YH, Liaw CC Tags: Pain Res Manag Source Type: research

Value of Anterior Band of the Inferior Glenohumeral Ligament Area as a Morphological Parameter of Adhesive Capsulitis.
Abstract Objective: Thickened inferior glenohumeral ligament (IGHL) is considered as one of the major morphological parameters of adhesive capsulitis (AC). Previous studies reported that the anterior band of inferior glenohumeral ligament thickness (aIGHLT) is correlated with shoulder capsular contracture, luxatio erecta humeri, and AC. However, the thickness varies from the measured angle. To reduce this measurement error, we devised a new morphological parameter, called the anterior band of inferior glenohumeral ligament area (aIGHLA). Methods: The aIGHL samples were collected from 54 patients with AC and f...
Source: Pain Research and Management - June 18, 2019 Category: Anesthesiology Authors: Bang YS, Park J, Lee SY, Park J, Park S, Joo Y, Kim YU, Lee YK Tags: Pain Res Manag Source Type: research

Chronic Widespread Pain and Fibromyalgia Syndrome: Life-Course Risk Markers in Young People.
Abstract Although the life-course concept of risk markers as potential etiological influences is well established in epidemiology, it has not featured in academic publications or clinical practice in the context of chronic widespread pain (CWP) and fibromyalgia syndrome (FMS). Studies of risk markers are required considerations for evaluation of patients and for research because there is no single cause, pathological feature, laboratory finding, or biomarker for CWP or FMS. The early-life risk markers identified by extensive literature review with best evidence for potential causal influence on the development and...
Source: Pain Research and Management - June 15, 2019 Category: Anesthesiology Authors: Tan AC, Jaaniste T, Champion D Tags: Pain Res Manag Source Type: research

Effects of a Newly Developed Therapeutic Deep Heating Device Using High Frequency in Patients with Shoulder Pain and Disability: A Pilot Study.
Conclusions: The newly developed HIPER-500® for high-frequency deep heat therapy showed similar effects to those of SonoStim® for relieving pain and improving physical performance in the patients of this study. HIPER-500® may be a useful modality for treating shoulder pain and improving physical activity in patients with shoulder disease. PMID: 31191789 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - June 15, 2019 Category: Anesthesiology Authors: Kim GW, Won YH, Park SH, Seo JH, Kim DH, Lee HN, Ko MH Tags: Pain Res Manag Source Type: research

A Better Way to Decrease Knee Swelling in Patients with Knee Osteoarthritis: A Single-Blind Randomised Controlled Trial.
In this study, we compared the effects of intermittent pneumatic compression along with conventional treatment with cold-pack treatment along with conventional treatment on clinical outcomes in patients with knee osteoarthritis. Methods: Eighty-nine patients with knee osteoarthritis participated in this study. One group received ultrasound, transcutaneous electrical nerve stimulation, electrical stimulation, exercise, and cold packs. The second group received ultrasound, transcutaneous electrical nerve stimulation, electrical stimulation, exercise, and intermittent pneumatic compression. Range of motion, muscle streng...
Source: Pain Research and Management - June 15, 2019 Category: Anesthesiology Authors: Sari Z, Aydoğdu O, Demirbüken İ, Yurdalan SU, Polat MG Tags: Pain Res Manag Source Type: research

Retrospective Analysis of Ultrasound-Guided Infraclavicular Block: Effect of Experience of Anesthesiologists on Volume of Local Anesthetic Administered.
Abstract Performing a block under ultrasound guidance effectively requires skill; however, inexperienced anesthesiologists often use high-dose LA to ensure success. We aimed to share our experience with the ultrasound-guided infraclavicular brachial plexus block (USGICB) for upper extremity surgeries and to determine changes in failure rate and local anesthetic dose administered with gaining adequate experience. With approval from the local ethics committee, a retrospective review of records of 2953 patients who underwent USGICB between November 2011 and March 2015 was performed for evaluating the following data: ...
Source: Pain Research and Management - June 15, 2019 Category: Anesthesiology Authors: Yeniocak T, Canbolat N Tags: Pain Res Manag Source Type: research

A New Device Improves Signs and Symptoms of TMD.
aco A Abstract Background: Temporomandibular joint dysfunction (TMD) therapy remains an open challenge for modern dentistry. Herein, we propose a new neuromuscular lingual device able to reduce signs and symptoms of TMD in female patients with chronic orofacial pain. Methods: 50 females with myofascial TMD according to RDC/TMD were randomly assigned to study (n = 25) and control groups (n = 25). At T0, both groups received sEMG/KNG and pain evaluation by the VAS scale. The study group received the ELIBA device (lingual elevator by Balercia) constructed under ULF-TENS (ultra-low-fre...
Source: Pain Research and Management - June 15, 2019 Category: Anesthesiology Authors: Cattaneo R, Pietropaoli D, Cooper BC, Capparè D, Ortu E, Monaco A Tags: Pain Res Manag Source Type: research

Cognitive Decline in Chronic Migraine with Nonsteroid Anti-inflammation Drug Overuse: A Cross-Sectional Study.
Abstract Background: Chronic migraine with medication overuse headache (CM-MOH) is the most common type of chronic migraine, and it increases risk of stroke and white matter lesions. These pathologic changes could induce cognitive decline. However, the alteration of cognitive function in CM-MOH patients is not established. Therefore, we took this study to reveal the cognitive performances in CM-MOH. Methods: This cross-sectional study was conducted between December 2015 and January 2017. Patients were divided into CM-MOH, CMwoMOH (chronic migraine without medication overuse), and MO (migraine without aura) gr...
Source: Pain Research and Management - June 15, 2019 Category: Anesthesiology Authors: Cai X, Xu X, Zhang A, Lin J, Wang X, He W, Fang Y Tags: Pain Res Manag Source Type: research

Characteristics of Chronic Pain among Head and Neck Cancer Patients Treated with Radiation Therapy: A Retrospective Study.
Abstract Pain is common among patients with head and neck cancer (HNC). However, there are very limited data on chronic pain among HNC patients treated with radiation therapy (XRT). In this retrospective study, we focused on the characteristics of chronic post-XRT pain in such patients. Post-XRT pain is common among HNC patients; however, we found discrepancy between frequency of treatment and frequency of chronic pain, suggesting poor documentation of pain in the medical records. Among patients who reported to have chronic post-XRT pain, most of them described having severe pain and used descriptors of neuropathi...
Source: Pain Research and Management - June 15, 2019 Category: Anesthesiology Authors: Kallurkar A, Kulkarni S, Delfino K, Ferraro D, Rao K Tags: Pain Res Manag Source Type: research

Microglial BDNF, PI3K, and p-ERK in the Spinal Cord Are Suppressed by Pulsed Radiofrequency on Dorsal Root Ganglion to Ease SNI-Induced Neuropathic Pain in Rats.
Abstract Background: Pulsed radiofrequency (PRF) on the dorsal root ganglion (DRG) has been applied to alleviate neuropathic pain effectively, yet the mechanisms underlying pain reduction owing to this treatment are not clarified completely. The activated microglia, brain-derived neurotrophic factor (BDNF), phosphatidylinositol 3-kinase (PI3K), and phosphorylated extracellular signal-regulated kinase (p-ERK) in the spinal cord were demonstrated to be involved in developing neuropathic pain. Also, it has been just known that PRF on DRG inhibits the microglial activation in nerve injury rats. Here, we aim to investi...
Source: Pain Research and Management - June 12, 2019 Category: Anesthesiology Authors: Xu X, Fu S, Shi X, Liu R Tags: Pain Res Manag Source Type: research

The Emerging Perspective of Morphine Tolerance: MicroRNAs.
Abstract Morphine has unfavorable side effects including analgesic tolerance. Morphine tolerance counteracts analgesic efficacy and drives dose escalation. The mechanisms underlying morphine tolerance remain disputed, which has prevented the development of therapies to maximize and sustain analgesic efficacy. Morphine tolerance is an adaptive process induced by chronic morphine that has been shown to result from complex alterations at the molecular level with μ opioid receptors (MORs), as well as at the synaptic, cellular, and circuit levels. MicroRNAs are noncoding RNAs that have been proposed to regulate gene...
Source: Pain Research and Management - June 12, 2019 Category: Anesthesiology Authors: Zhang TJ, Qiu Y, Hua Z Tags: Pain Res Manag Source Type: research

Acute Pain in the African Prehospital Setting: A Scoping Review.
Conclusions: Only six publications addressing prehospital acute pain care in Africa could be identified, possibly indicative of a knowledge gap. Future research is indicated to enable a better understanding of the epidemiology of acute pain and barriers and enablers of acute pain care and to develop evidence-based clinical practice guidelines (CPGs) catering for all EMS systems in Africa. Additionally, educational initiatives should be implemented to improve the quality of acute pain care and to monitor quality through continuous quality improvement (CQI) programs. PMID: 31149317 [PubMed - in process] (Source: Pain Re...
Source: Pain Research and Management - June 4, 2019 Category: Anesthesiology Authors: Lourens A, McCaul M, Parker R, Hodkinson P Tags: Pain Res Manag Source Type: research

Reward Processing under Chronic Pain from the Perspective of "Liking" and "Wanting": A Narrative Review.
Reward Processing under Chronic Pain from the Perspective of "Liking" and "Wanting": A Narrative Review. Pain Res Manag. 2019;2019:6760121 Authors: Liu X, Wang N, Gu L, Guo J, Wang J, Luo F Abstract The therapeutic goals of patients with chronic pain are not only to relieve pain but also to improve the quality of life. Chronic pain negatively affects various aspects of daily life, such as by decreasing the motivation to work and reward sensitivity, which may lead to difficulties in daily life or even unemployment. Human and animal studies have shown that chronic pain damages reward...
Source: Pain Research and Management - June 4, 2019 Category: Anesthesiology Authors: Liu X, Wang N, Gu L, Guo J, Wang J, Luo F Tags: Pain Res Manag Source Type: research

The Mediating Effect of Central Sensitization on the Relation between Pain Intensity and Psychological Factors: A Cross-Sectional Study with Mediation Analysis.
Conclusions: The relationship among anxiety symptoms, depression symptoms, and pain intensity was completely mediated by CS. Furthermore, the relationship between catastrophic thinking and pain intensity was partially mediated by CS. Our findings suggest that CS mediates relation between psychological factors and pain intensity, and CS-focused intervention may be important. PMID: 31089402 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - May 16, 2019 Category: Anesthesiology Authors: Shigetoh H, Tanaka Y, Koga M, Osumi M, Morioka S Tags: Pain Res Manag Source Type: research

Risk Factors Associated with Upper Extremity Musculoskeletal Disorders among Barbers in Gondar Town, Northwest Ethiopia, 2018: A Cross-Sectional Study.
Abstract Background: Work-related upper extremity musculoskeletal disorders (WUEDs) often present remarkable health and economic burdens on society. Occupational barbers are usually neglected both in research and policy actions, mainly in developing countries, and hence are likely subjected to the conditions. So far, information about factors that influence WUEDs among barbers in Ethiopia is inconclusive. Therefore, this study aimed to evaluate prevalence and factors associated with WUEDs among barbers in Gondar town, Ethiopia. Methods: We conducted a cross-sectional study from March to April 2018. A sample o...
Source: Pain Research and Management - May 12, 2019 Category: Anesthesiology Authors: Mekonnen TH, Abere G, Olkeba SW Tags: Pain Res Manag Source Type: research

Comparison of Nonimage- and Fluoroscopy-Guided Interlaminar Epidural Block: A Matched Paired Analysis in the Same Individuals.
Conclusions: In this study, both blind and image-guided L-ESI techniques included similar extents of postprocedural outcomes and complications. Physicians should consider the risks associated with the two different techniques overall and develop ways to individualize the procedure to decrease the risk of complications and improve the positive outcomes of lumbar epidural steroid injections. PMID: 31065303 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - May 9, 2019 Category: Anesthesiology Authors: Yoon SH, Park H, Lee K, Han H, Kang KN, Lee G, Han YA, Choi SS Tags: Pain Res Manag Source Type: research

Living with Chronic Pain: A Qualitative Study of the Daily Life of Older People with Chronic Pain in Chile.
pos M Abstract One of the main causes of chronic pain in older people is spine deformity, an abnormal curvature of the spine. The purpose of this study is to improve understanding of the experience of chronic pain produced by spinal deformity in older people and understand how cultural factors may affect this experience. A qualitative study was performed with 10 older people. Participants were encouraged to describe a typical day in their life, including the factors that affect their pain and how their quality of life had been affected since experiencing chronic pain. The semistructured interviews were transcribed...
Source: Pain Research and Management - May 9, 2019 Category: Anesthesiology Authors: Rodríguez I, Abarca E, Herskovic V, Campos M Tags: Pain Res Manag Source Type: research

The Chinese Association for the Study of Pain (CASP): Expert Consensus on the Cervicogenic Headache.
This article summarizes the conclusions of the consensus group regarding the epidemiology, etiology, clinical features, diagnosis, differential diagnosis, treatment, and rehabilitation of cervicogenic headache in China. PMID: 31065305 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - May 9, 2019 Category: Anesthesiology Authors: Xiao H, Peng B, Ma K, Huang D, Liu X, Lu Y, Liu Q, Lu L, Liu J, Li Y, Song T, Tao W, Shen W, Yang X, Wang L, Zhang X, Zhuang Z, Liu H, Liu Y Tags: Pain Res Manag Source Type: research

Analyzing the Influence of Modic Changes on Patients with Lower Back Pain Undergoing Conservative Treatment.
Conclusions: The existence of MCs affects the outcomes of nonsurgical treatment in patients with LBP. However, symptoms can be improved after an additional round of treatment for Modic type I changes, while this is not confirmed for Modic type II changes. PMID: 31015885 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - April 26, 2019 Category: Anesthesiology Authors: Chen Y, Yang H, Zhang L, Wang Y, Zou J Tags: Pain Res Manag Source Type: research

Cross-Cultural Validation of the English Chronic Pain Myth Scale in Emergency Nurses.
Conclusion: Our results provide support for the preliminary validity of the English CPMS to measure knowledge, beliefs, and attitudes towards CP among emergency nurses in the United States. PMID: 31001368 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - April 21, 2019 Category: Anesthesiology Authors: Martorella G, Lacasse A, Kostic M, Schluck G Tags: Pain Res Manag Source Type: research

Comparison of Early Effectiveness of Three Different Intervention Methods in Patients with Chronic Orofacial Pain: A Randomized, Controlled Clinical Trial.
Conclusions: Occlusal appliances in conjunction with NSAID showed better orofacial pain relief after 3 weeks of therapy, compared to the use of occlusal appliances alone or in conjunction with dry needling. Additionally, differences between pain perception and quality of life between OA and DN + OA groups were not found to be statistically significant. PMID: 30984320 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - April 16, 2019 Category: Anesthesiology Authors: Dalewski B, Kamińska A, Szydłowski M, Kozak M, Sobolewska E Tags: Pain Res Manag Source Type: research

Locating the Site of Neuropathic Pain In Vivo Using MMP-12-Targeted Magnetic Nanoparticles.
Abstract Neuropathic pain remains underrecognised and ineffectively treated in chronic pain sufferers. Consequently, their quality of life is considerably reduced, and substantial healthcare costs are incurred. The anatomical location of pain must be identified for definitive diagnosis, but current neuropsychological tools cannot do so. Matrix metalloproteinases (MMP) are thought to maintain peripheral neuroinflammation, and MMP-12 is elevated particularly in such pathological conditions. Magnetic resonance imaging (MRI) of the peripheral nervous system has made headway, owing to its high-contrast resolution and m...
Source: Pain Research and Management - April 9, 2019 Category: Anesthesiology Authors: Husain SF, Lam RWM, Hu T, Ng MWF, Liau ZQG, Nagata K, Khanna S, Lam Y, Bhakoo K, Ho RCM, Wong HK Tags: Pain Res Manag Source Type: research

Effect of Injectate Viscosity on Epidural Distribution in Lumbar Transforaminal Epidural Steroid Injection.
Conclusion: The epidural distribution of the contrast agent through the transforaminal approach was most affected by the injectate volume and was also partly affected by the viscosity. PMID: 30944685 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - April 6, 2019 Category: Anesthesiology Authors: Choi J, Kim N, Smuck M, Lee SH Tags: Pain Res Manag Source Type: research

Postoperative Analgesic Effects of Different Doses of Epidural Hydromorphone Coadministered with Ropivacaine after Cesarean Section: A Randomized Controlled Trial.
Conclusions: Epidural administration of 0.6 mg hydromorphone coadministered with ropivacaine after cesarean section provided satisfactory pain relief with less sulfentanil consumption. This trial is registered with ChiCTR-IPR-16010026. PMID: 30944686 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - April 6, 2019 Category: Anesthesiology Authors: Yang M, Wang L, Chen H, Tang Y, Chen X Tags: Pain Res Manag Source Type: research

Differences in Nonspecific Low Back Pain between Young Adult Females with and without Lumbar Scoliosis.
Conclusions: The characteristics of NSLBP experienced by patients with lumbar scoliosis were distinct from those of NSLBP experienced by nonscoliotic patients. The treatment of NSLBP in scoliotic patients should be different from that in nonscoliotic patients. PMID: 30944687 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - April 6, 2019 Category: Anesthesiology Authors: Yuan W, Shen J, Chen L, Wang H, Yu K, Cong H, Zhou J, Lin Y Tags: Pain Res Manag Source Type: research

Computer-Assisted Design Template Guided Percutaneous Radiofrequency Thermocoagulation through Foramen Rotundum for Treatment of Isolated V2 Trigeminal Neuralgia: A Retrospective Case-Control Study.
Conclusions: CAD template is a safe and precise navigation instrument for RFT treatment of isolated V2 trigeminal neuralgia via the foramen rotundum. Therefore, this novel tool is worthy of clinical promotion. PMID: 30944688 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - April 6, 2019 Category: Anesthesiology Authors: Wang R, Han Y, Lu L Tags: Pain Res Manag Source Type: research

Optimizing the Management and Outcomes of Failed Back Surgery Syndrome: A Consensus Statement on Definition and Outlines for Patient Assessment.
Abstract Failed back surgery syndrome (FBSS) is a controversial term for identifying patients affected by new, recurrent, or persistent pain in the low back and/or legs following spinal surgery. The lack of a comprehensive standardized care pathway compromises the appropriate management of FBSS patients, which is associated with a heavy financial burden. An international panel of spine surgeons, neurosurgeons, and pain specialists with a particular interest in FBSS established the chronic back and leg pain (CBLP) network with the aim of addressing the challenges and barriers in the clinical management of FBSS pati...
Source: Pain Research and Management - March 27, 2019 Category: Anesthesiology Authors: Rigoard P, Gatzinsky K, Deneuville JP, Duyvendak W, Naiditch N, Van Buyten JP, Eldabe S Tags: Pain Res Manag Source Type: research

Pain Acceptance and Its Associated Factors among Cancer Patients in Mainland China: A Cross-Sectional Study.
Conclusions: The findings suggest that the prevalence of pain acceptance is relatively low for Chinese cancer patients. The cancer pain acceptance is affected by age, gender, pain duration, number of pain sites, and duration of taking analgesics. The acceptance of cancer pain is negatively correlated with depression and anxiety. Therefore, patients with risk factors for low pain acceptance should receive more attention in Chinese medical settings. PMID: 30906486 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - March 26, 2019 Category: Anesthesiology Authors: Xu X, Ou M, Xie C, Cheng Q, Chen Y Tags: Pain Res Manag Source Type: research

Pain Behaviour Scale (PaBS): An Exploratory Study of Reliability and Construct Validity in a Chronic Low Back Pain Population.
Conclusion: The Pain Behaviour Scale is a valid and reliable tool for measuring the presence and severity of pain behaviour, and the physical performance tests are reliable tests. PMID: 30863470 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - March 15, 2019 Category: Anesthesiology Authors: Alamam DM, Leaver A, Moloney N, Alsobayel HI, Alashaikh G, Mackey MG Tags: Pain Res Manag Source Type: research

Comparison of Ultrasound-Guided Subcostal Transversus Abdominis Plane Block and Quadratus Lumborum Block in Laparoscopic Cholecystectomy: A Prospective, Randomized, Controlled Clinical Study.
pal S Abstract Background: The aim of this study was to compare the effectiveness of ultrasound-guided (USG) subcostal transversus abdominis plane (TAP) block and quadratus lumborum (QL) block as preventive analgesia methods after laparoscopic cholecystectomy. Methods: A total of 120 patients, 18-75 years of age, were separated into 2 groups preoperatively. Patients in group TAP (n = 60) received 0.3 ml/kg bupivacaine with USG bilateral subcostal TAP block; patients in group QL (n = 60) received 0.3 ml/kg bupivacaine with USG bilateral QL block. Patients were a...
Source: Pain Research and Management - March 15, 2019 Category: Anesthesiology Authors: Baytar Ç, Yılmaz C, Karasu D, Topal S Tags: Pain Res Manag Source Type: research

Perspective of Pain Clinicians in Three Global Cities on Local Barriers to Providing Care for Chronic Noncancer Pain Patients.
This study demonstrates a simple methodology for informing global and local efforts to improve access to and implementation of CNCP services globally. PMID: 30863473 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - March 15, 2019 Category: Anesthesiology Authors: Lakha SF, Ballantyne P, Badr H, Agboatwala M, Mailis A, Pennefather P Tags: Pain Res Manag Source Type: research

Gabapentin versus Transdermal Fentanyl Matrix for the Alleviation of Chronic Neuropathic Pain of Radicular Origin: A Randomized Blind Multicentered Parallel-Group Noninferiority Trial.
This study demonstrated that the analgesic effect of fentanyl matrix is noninferior in comparison with gabapentin and supports the use of fentanyl matrix as an effective and safe treatment for moderate-to-severe chronic neuropathic pain. This trial is registered with NCT01127100. PMID: 30863474 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - March 15, 2019 Category: Anesthesiology Authors: Hwang CJ, Lee JH, Kim JH, Min SH, Park KW, Seo HY, Song KS Tags: Pain Res Manag Source Type: research

Role of p120 Catenin in Epac1-Induced Chronic Postsurgical Pain in Rats.
Abstract Chronic postsurgical pain (CPSP) is a chronic pain state that is difficult to be treated clinically. A series of complicated changes have been produced from nociceptive stimulation to the occurrence and development of postsurgical pain. Many mechanisms remain unclear. In order to study the role of intercellular gap junctions in inducing inflammatory microenvironment at the beginning of nociceptor after operation, the model of skin/muscle incision and retraction (SMIR) was established. We observed the changes of the expression of exchange proteins directly activated by cAMP-1 (Epac1) and p120 catenin (p120...
Source: Pain Research and Management - March 15, 2019 Category: Anesthesiology Authors: Pan P, Huang SS, Shen SR, Lu CE, Qin YB, Zhang JL, Cao S Tags: Pain Res Manag Source Type: research

Comparison of Different Histone Deacetylase Inhibitors in Attenuating Inflammatory Pain in Rats.
Abstract Histone deacetylase inhibitors (HDACIs), which interfere with the epigenetic process of histone acetylation, have shown analgesic effects in animal models of persistent pain. The HDAC family comprises 18 genes; however, the different effects of distinct classes of HDACIs on pain relief remain unclear. The aim of this study was to determine the efficacy of these HDACIs on attenuating thermal hyperalgesia in persistent inflammatory pain. Persistent inflammatory pain was induced by injecting Complete Freund's Adjuvant (CFA) into the left hind paw of rats. Then, HDACIs targeting class I (entinostat (MS-275)) ...
Source: Pain Research and Management - March 1, 2019 Category: Anesthesiology Authors: Mao Y, Zhou J, Liu X, Gu E, Zhang Z, Tao W Tags: Pain Res Manag Source Type: research

A Comparison of Pain between Parkinson's Disease and Multiple System Atrophy: A Clinical Cross-Sectional Survey.
This study aimed to assess the prevalence, characteristics, therapy (especially the effect of dopaminergic therapy), and associated symptoms of pain in Parkinson's disease and multiple system atrophy (MSA) patients. Methods: Seventy-one PD patients, sixty-five MSA patients, and forty age-matched healthy controls were enrolled and evaluated by using the German pain questionnaire and visual analogue scale (VAS). In addition, the influence of pain in PD patients on anxiety, depression, and the quality of life was assessed with the Hospital Anxiety and Depression Scale (HADS) and Parkinson's Disease Questionnaire (PDQ-39)...
Source: Pain Research and Management - February 27, 2019 Category: Anesthesiology Authors: You HY, Wu L, Yang HT, Yang C, Ding XL Tags: Pain Res Manag Source Type: research

Pain Clinic in Tibet, China: A Single-Center Retrospective Study.
This study collected and analyzed the data of medical records of pain clinic in Tibet Autonomous Region People's Hospital from September 2017 to August 2018. The results showed that the total amounts of patients visiting pain clinic were very small, the most common pain diseases were postherpetic neuralgia and sciatica, and more female patients visited the pain clinic than male patients. All these results indicate that the hospital and government need to pay more attention to the development and promotion of pain medicine in Tibet to make Tibetans being accessed to high-quality pain clinic service. PMID: 30766644 [Pub...
Source: Pain Research and Management - February 17, 2019 Category: Anesthesiology Authors: Shen L, Zhang X, Dawawuzhu, Labaciren, Zhang Y, Xu Z, Huang Y Tags: Pain Res Manag Source Type: research

Clinical Efficacy and Safety of Trans-Sacral Epiduroscopic Laser Decompression Compared to Percutaneous Epidural Neuroplasty.
This study evaluated the clinical efficacy and safety of SELD compared to PEN, as well as the change in protruded disc volume after SELD through pre- and postoperative magnetic resonance imaging (MRI), in patients with HLD. Thirty consecutive patients underwent SELD (SELD group), and 45 patients underwent PEN (PEN group). The Visual Analog Scale (VAS) for leg pain; Oswestry Disability Index (ODI); 12-Item Short-Form Health Survey (SF-12); preoperative and postoperative 4-, 12-, and 24-week Macnab criteria; and preoperative and 24-week postoperative lumbar spinal MRIs after SELD were obtained. There was no significant diffe...
Source: Pain Research and Management - February 14, 2019 Category: Anesthesiology Authors: Moon BJ, Yi S, Ha Y, Kim KN, Yoon DH, Shin DA Tags: Pain Res Manag Source Type: research

Hypertension and Postoperative Pain: A Prospective Observational Study.
Conclusion: We agree that hypertensive hypoanalgesia exists in some experimental settings. The mechanism linking postoperative pain and hypertension is far more complex than we initially believed. Therefore, more studies are required to investigate the roles that antihypertensive drugs, sex, and psychological stress play. Antihypertensive drugs may play a crucial role in mediating the relationship between pain and hypertension. Psychosocial factors were discussed but were not examined. PMID: 30728877 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - February 9, 2019 Category: Anesthesiology Authors: Chiang HL, Huang YC, Lin HS, Chan MH, Chia YY Tags: Pain Res Manag Source Type: research