The Impact of Cognitive Anxiety and the Rating of Pain on Care Processes in a Vigilance Task: The Important Part Played by Age.
This study's aim is therefore to analyse the impact of emotional variables (anxiety and depression), the rating of pain, and age on vigilance processes in a sample of patients with chronic pain. To do so, the attentional performance of a cohort of 52 patients with chronic pain was measured through the use of a modified dot-probe task. Furthermore, all the participants were evaluated using the following self-report measures: Beck's Depression Inventory-II (BDI-II), the McGill Pain Questionnaire, and the Pain Anxiety Symptoms Scale-20 (PASS-20). Stepwise multiple linear regression analysis revealed a significant negative cor...
Source: Pain Research and Management - May 15, 2020 Category: Anesthesiology Authors: Pinel L, Perez-Nieto MA, Redondo M, Rodríguez-Rodríguez L, Mateos LL Tags: Pain Res Manag Source Type: research

Effects of Rhythmic Sensory Stimulation on Ehlers-Danlos Syndrome: A Pilot Study.
Abstract Ehlers-Danlos syndrome (EDS) is a connective tissue disorder characterized by joint hypermobility and skin extensibility and is often accompanied by chronic pain. Rhythmic sensory stimulation (RSS) can be defined as the stimulation of the senses in a periodic manner within a range of low frequencies. Music plus sound delivered through a vibroacoustic device is a form of RSS and has demonstrated utility in managing pain. In this current study, we conducted an open-label pilot study of 15 patients with hypermobile EDS using RSS as the intervention. Posttreatment improvements were seen in 11 of the 15 patien...
Source: Pain Research and Management - May 15, 2020 Category: Anesthesiology Authors: Vuong V, Mosabbir A, Paneduro D, Picard L, Faghfoury H, Evans M, Gordon A, Bartel L Tags: Pain Res Manag Source Type: research

Feasibility of the Epiduroscopy Simulator as a Training Tool: A Pilot Study.
Abstract Epiduroscopy is a type of spinal intervention that visualizes the epidural space through the sacral hiatus using a fiberoptic scope. However, it is technically difficult to perform compared to conventional interventions and susceptible to complications. Surgery simulator has been shown to be a promising modality for medical education. To develop the epiduroscopy simulator and prove its usefulness for epiduroscopy training, we performed a case-control study including a total of 20 physicians. The participants were classified as the expert group with more than 30 epiduroscopy experiences and the beginner gr...
Source: Pain Research and Management - May 15, 2020 Category: Anesthesiology Authors: Lee JJ, Ko J, Yun Y, Jang SW, Ha Y, Kim YS, Shin DA Tags: Pain Res Manag Source Type: research

Psychosocial Underpinnings of Pain and Sleep Disturbance in Safety-Net Primary Care Patients.
Conclusions: These findings illustrate the interplay of psychosocial factors with chronic pain and sleep disturbance in a sample of low-income, predominantly African-American patients seeking care at a safety-net primary care clinic. The findings support integrated primary care as a way to target not only behavioral health issues but also the psychosocial factors entangled with physical health. PMID: 32399128 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - May 15, 2020 Category: Anesthesiology Authors: Griffin S, Tan J, Perrin PB, Williams AB, Smith ER, Rybarczyk B Tags: Pain Res Manag Source Type: research

Analysis of Spinopelvic Sagittal Balance and Persistent Low Back Pain (PLBP) for Degenerative Spondylolisthesis (DS) following Posterior Lumbar Interbody Fusion (PLIF).
Conclusion: The sagittal balance parameters and clinical outcomes can be improved markedly via PLIF for treating DS. Restoration of SL and PT was correlated with satisfactory outcomes, and adequate improvement of PT may have positive impact on reducing PLBP. PMID: 32399129 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - May 15, 2020 Category: Anesthesiology Authors: He S, Zhang Y, Ji W, Liu H, He F, Chen A, Yang H, Pi B Tags: Pain Res Manag Source Type: research

A Clinical Randomized Controlled Trial of Acupuncture Treatment of Gastroparesis Using Different Acupoints.
Abstract Objective: To explore the effect of "selecting acupoints by site" on the synergy effect of "acupoint compatibility" according to the clinical efficacy of acupuncture treatment of patients with gastroparesis. Methods: A total of 99 patients who met the diagnostic criteria for gastroparesis were enrolled in 3 clinical centers and randomly divided into group A (33 cases), group B (33 cases, 1 case of shedding), and group C (33 cases, 1 case of shedding). In group A, acupuncture was performed at Zhongwan (CV 12) and Zusanli (ST 36); in group B, acupuncture was performed at Neiguan (PC...
Source: Pain Research and Management - May 15, 2020 Category: Anesthesiology Authors: Xuefen W, Ping L, Li L, Xiaoli C, Yue Z Tags: Pain Res Manag Source Type: research

Oblique Lumbar Interbody Fusion with Stand-Alone Cages for the Treatment of Degenerative Lumbar Spondylolisthesis: A Retrospective Study with 1-Year Follow-Up.
Abstract Patients with degenerative lumbar spondylolisthesis (DLS) often suffer from years of low back pain (LBP) due to instability of the lumbar spine and the reduction of disc height. Since January 2016, we have performed oblique lateral interbody fusion (OLIF) on 154 patients. Among these, 56 patients who suffered from DLS underwent OLIF with stand-alone cages. Forty-two patients with a follow-up time that exceeded 1-year were enrolled for this study. The forty-two patients were followed up for at least one year. Operation segments ranged from L3-4 to L4-5. All the patients were with 1-level fusion. The mean p...
Source: Pain Research and Management - May 15, 2020 Category: Anesthesiology Authors: Huo Y, Yang D, Ma L, Wang H, Ding W, Yang S Tags: Pain Res Manag Source Type: research

Corrigendum to "A New Device Improves Signs and Symptoms of TMD".
Corrigendum to "A New Device Improves Signs and Symptoms of TMD". Pain Res Manag. 2020;2020:9465080 Authors: Monaco A, Pietropaoli D, Iapnor, Cooper BC, Ortu E Abstract [This corrects the article DOI: 10.1155/2019/5646143.]. PMID: 32399132 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - May 15, 2020 Category: Anesthesiology Authors: Monaco A, Pietropaoli D, Iapnor, Cooper BC, Ortu E Tags: Pain Res Manag Source Type: research

Efficacy and Safety of Continuous Paravertebral Block after Minimally Invasive Radical Esophagectomy for Esophageal Cancer.
Abstract Objective: To compare the effects of continuous paravertebral block analgesia and patient-controlled intravenous analgesia after minimally invasive radical esophagectomy for esophageal cancer and their effects on postoperative recovery. Methods: A retrospective analysis was performed among 233 patients who underwent minimally invasive esophageal cancer radical operation and met the requirements, including 87 patients (group C) who were successfully placed with a continuous paravertebral block device under direct vision and 146 patients (group P) who used a patient-controlled intravenous analgesia dev...
Source: Pain Research and Management - May 8, 2020 Category: Anesthesiology Authors: Zhang S, Liu H, Cai H Tags: Pain Res Manag Source Type: research

Tolerability of Palmitoylethanolamide in a Pediatric Population Suffering from Migraine: A Pilot Study.
Abstract Background: Palmitoylethanolamide (PEA) is emerging as a new therapeutic approach in pain and inflammatory conditions, and it has been evaluated in studies on various painful diseases. The aim of this open-label study was to evaluate the efficacy of ultramicronized PEA (umPEA) in the prophylactic treatment of migraine. Methods: The study included 70 patients with mean age of 10.3 ± 2.7 (24.5% M and 75.5% F). All patients had a diagnosis of migraine without aura (ICHD 3 criteria) and received umPEA (600 mg/day orally) for three months. We compared the attack frequency (AF) ...
Source: Pain Research and Management - May 8, 2020 Category: Anesthesiology Authors: Papetti L, Sforza G, Tullo G, Alaimo di Loro P, Moavero R, Ursitti F, Ferilli MAN, Tarantino S, Vigevano F, Valeriani M Tags: Pain Res Manag Source Type: research

Assessment of the Level of Pain Intensity and the Level of Anxiety Treated as State and Trait in Patients with Osteoarthritis of the Limbs.
Conclusions: 1. Spa therapy and treatment performed in an outpatient clinic reduce the level of pain and anxiety in patients with degenerative disease of the musculoskeletal system. 2. It was found that the therapy conducted in the spa was more effective in lowering the level of pain and anxiety. This trial is registered with NCT03405350. PMID: 32377287 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - May 8, 2020 Category: Anesthesiology Authors: Kuciel-Lewandowska J, Kasperczak M, Lewandowski ŁB, Paprocka-Borowicz M Tags: Pain Res Manag Source Type: research

Electroacupuncture Treatment Suppresses Transcription Factor IRF8 in Spinal Cord of Rats with Spared Nerve Injury.
Conclusion: This experiment highlighted that 2 Hz EA can inhibit IRF8 expression and microglial activation in the spinal cord of SNI rats. Hence, targeting IRF8 may be a promising therapeutic strategy for 2 Hz EA treatment of neuropathic pain. PMID: 32351637 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - May 1, 2020 Category: Anesthesiology Authors: Wang Y, Xue M, Xia YY, Jiang Q, Huang ZH, Huang C Tags: Pain Res Manag Source Type: research

Standard Correction of Vision Worsens EMG Activity of Pericranial Muscles in Chronic TMD Subjects.
The objective of this work was to evaluate the effects of standard vision correction on EMG in subjects suffering from TMD compared with application of the same vision treatments to non-TMD subjects. 40 subjects were enrolled in this study. The test group included 20 myopic subjects and also included patients with TMD. The control group included 20 healthy myopic subjects. All of the participants underwent a complete ocular examination and a sEMG analysis. The results showed that TMD subjects with vision disorders that are corrected with standard glasses present EMG values that are significantly higher than those presented...
Source: Pain Research and Management - May 1, 2020 Category: Anesthesiology Authors: Monaco A, Ortu E, Giannoni M, D'Andrea P, Cattaneo R, Mummolo A, Pietropaoli D Tags: Pain Res Manag Source Type: research

Tapentadol Prolonged Release for Severe Chronic Osteoarthritis Pain in the Elderly-A Subgroup Analysis of Routine Clinical Practice Data.
Conclusion: Tapentadol PR provided effective and well-tolerated treatment of severe chronic OA pain for elderly patients in routine clinical practice. The favorable tolerability profile in particular suggests tapentadol PR as a treatment option before classical strong opioids are considered. PMID: 32351639 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - May 1, 2020 Category: Anesthesiology Authors: Schwittay A, Sohns M, Heckes B, Elling C Tags: Pain Res Manag Source Type: research

Sleep Disturbance and Its Clinical Implication in Patients with Adult Spinal Deformity: Comparison with Lumbar Spinal Stenosis.
Conclusions: Because sleep quality is a critical factor in augmenting back pain in patients with ASD, this study underlines the need to investigate sleep quality during the routine examination of patients with ASD. PMID: 32351640 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - May 1, 2020 Category: Anesthesiology Authors: Kim HJ, Hong SJ, Park JH, Ki H Tags: Pain Res Manag Source Type: research

Molecular Aspects of Regional Pain Syndrome.
Abstract The purpose of this review is to summarize the pathophysiology of complex regional pain syndrome (CRPS), the underlying molecular mechanisms, and potential treatment options for its management. CRPS is a multifactorial pain condition. CRPS is characterized by prolonged or excessive pain and changes in skin color and temperature, and/or swelling in the affected area, and is generally caused by stimuli that lead to tissue damage. An inflammatory response involving various cytokines and autoantibodies is generated in response to acute trauma/stress. Chronic phase pathophysiology is more complex, involving th...
Source: Pain Research and Management - May 1, 2020 Category: Anesthesiology Authors: Baronio M, Sadia H, Paolacci S, Prestamburgo D, Miotti D, Guardamagna VA, Natalini G, Sullivan SGB, Bertelli M Tags: Pain Res Manag Source Type: research

Socially-Assistive Robots Using Empathy to Reduce Pain and Distress during Peripheral IV Placement in Children.
Conclusions: Children were able to identify SAR designed to display empathic characteristics and reported it helped with IV insertion pain and fear. Mean scores of self-reported or objective pain and fear scales were the lowest in the empathy group and the highest in the distraction condition before and after IV insertion. This result suggests empathy improves SAR functionality when used for painful medical procedures and informs future research into SAR for pain management. PMID: 32351642 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - May 1, 2020 Category: Anesthesiology Authors: Trost MJ, Chrysilla G, Gold JI, Matarić M Tags: Pain Res Manag Source Type: research

Correlation between Galectin-3 and Early Herpes Zoster Neuralgia and Postherpetic Neuralgia: A Retrospective Clinical Observation.
This study aims to explore the value of serum galectin-3 in patients with herpes zoster neuralgia (HZN) and postherpetic neuralgia (PHN) and other factors influencing HZN and PHN occurrence. Samples from forty patients with herpes zoster neuralgia (HZN) (Group H), 40 patients with nonherpes zoster neuralgia (Group N), and 20 cases of health check-up were collected. Patients were divided into PHN group (Group A) and non-PHN group (Group B) according to the occurrence of PHN in Group H. Galectin-3, T-lymphocyte subsets, and IL-6 were recorded in all patients. The changes of galectin-3 in patients with early HZN and PHN were ...
Source: Pain Research and Management - May 1, 2020 Category: Anesthesiology Authors: Wang T, Fei Y, Yao M, Tao J, Deng J, Huang B Tags: Pain Res Manag Source Type: research

Effects of the Characteristics and Duration of Chronic Pain on Psychosomatic Function in the Community-Dwelling Elderly Population.
This study aimed to evaluate the characteristics of CP in the community-dwelling elderly population and to investigate the effects of different periods of CP on cognitive and psychological functions. A total of 187 community-dwelling elderly people met the inclusion criteria and were included in this cross-sectional study. The survey items included demographic data (age and gender), pain-related questionnaires, psychological and cognitive functions, and sleep status. The duration of CP was investigated using three categories: no pain and pain for ≤1 year and ≥1 year. A logistic regression analysis was performed to id...
Source: Pain Research and Management - April 25, 2020 Category: Anesthesiology Authors: Hida M, Nakamura M, Imaoka M, Nakao H, Tasaki F, Omizu T, Takeda M, Ohnishi T, Wada C Tags: Pain Res Manag Source Type: research

How to Choose Platelet-Rich Plasma or Hyaluronic Acid for the Treatment of Knee Osteoarthritis in Overweight or Obese Patients: A Meta-Analysis.
Conclusions: For overweight or obese patients with knee OA, intra-articular injection of PRP in a short time was not necessarily superior to HA, but long-term use was better than HA in pain and functional relief. PMID: 32322326 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - April 25, 2020 Category: Anesthesiology Authors: Luo P, Xiong Z, Sun W, Shi L, Gao F, Li Z Tags: Pain Res Manag Source Type: research

Prevalence and Risk Factors for Opioid-Induced Constipation in an Older National Veteran Cohort.
Conclusions: There were several novel covariates found that are seen in the all-cause chronic constipation literature but have not been reported for opioid-induced constipation. Some are modifiable covariates, particularly medication coadministration, which may assist clinicians and researchers in risk stratification efforts when initiating opioid medications. The integration of CMS data supports the robustness of the analysis and may be of interest in the elderly population warranting future examination. PMID: 32318129 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - April 24, 2020 Category: Anesthesiology Authors: FitzHenry F, Eden SK, Denton J, Cao H, Cao A, Reeves R, Chen G, Gobbel G, Wells N, Matheny ME Tags: Pain Res Manag Source Type: research

Effectiveness of Acupuncture for Lateral Epicondylitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This study aimed at assessing the clinical effectiveness of acupuncture for lateral epicondylitis (LE). Methods: The following databases were systematically searched: China National Knowledge Infrastructure, Chinese Science and Technology Periodical Database, Wan Fang database, Chinese Biomedicine Literature, PubMed, EMBASE, and Cochrane Library from inception to May 2019. Randomized controlled trials (RCTs) meeting the inclusion criteria were included. RevMan 5.3 software was used to conduct meta-analyses. The study quality was evaluated with the Cochrane risk of bias. Results: Ten RCTs involving 796 individuals...
Source: Pain Research and Management - April 24, 2020 Category: Anesthesiology Authors: Zhou Y, Guo Y, Zhou R, Wu P, Liang F, Yang Z Tags: Pain Res Manag Source Type: research

Evaluation of Treatment Patterns and Direct Costs Associated with the Management of Neuropathic Pain.
Conclusions: Patients with neuropathic pain in Colombia are being diagnosed late, are using therapeutic agents not recommended as first-line treatment by clinical practice guidelines, and are being treated for short periods of time. PMID: 32318131 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - April 24, 2020 Category: Anesthesiology Authors: Machado-Duque ME, Gaviria-Mendoza A, Machado-Alba JE, Castaño N Tags: Pain Res Manag Source Type: research

Pain Relieving Effect of Intraoperative Chemical Splanchnicectomy of Celiac Ganglions in Patients with Resectable Pancreatic or Gastric Masses: A Randomized Clinical Trial.
This study aims to determine if splanchnicectomy by alcohol neurolysis can relieve postoperative pain after gastrectomy and Whipple surgery. The study explores differences in outcomes at first four months after surgery. Methods: Fifty-eight patients with gastric and 60 patients with pancreatic resectable masses were included (28 were lost to follow-up). Each randomized in control and intervention subgroups. Intervention subgroups underwent chemical blockage of celiac ganglions by ethanol injection at both sides of suprapancreatic aorta. Participants were asked to report their pain intensity according to the Visual Ana...
Source: Pain Research and Management - April 18, 2020 Category: Anesthesiology Authors: Vahedian J, Saraee A, Baghai Wadji M, Safari S, Chavoshi Khamneh A Tags: Pain Res Manag Source Type: research

The Roles of Skin Fibroblasts at Local Acupoints in Chrono-Acupuncture.
Conclusion: The remodeling difference of fibroblast cytoskeleton after receiving acupuncture treatment could be one of the peripheral bases of the chrono-acupuncture. PMID: 32300383 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - April 18, 2020 Category: Anesthesiology Authors: Liu N, Zhao Z, Zhou Q, Zhang X, Wang Y, Huang S, Cai D Tags: Pain Res Manag Source Type: research

Effectiveness and Safety of Acupuncture for Migraine: An Overview of Systematic Reviews.
Conclusions: Based on high quality of evidence, we concluded that acupuncture may be an effective and safe therapy for migraine. However, the quality of SRs in acupuncture for migraine still needs more improvement. PMID: 32269669 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - April 11, 2020 Category: Anesthesiology Authors: Li YX, Xiao XL, Zhong DL, Luo LJ, Yang H, Zhou J, He MX, Shi LH, Li J, Zheng H, Jin RJ Tags: Pain Res Manag Source Type: research

Ultrasound-Guided Transmuscular Quadratus Lumborum Block Reduces Postoperative Pain Intensity in Patients Undergoing Total Hip Arthroplasty: A Randomized, Double-Blind, Placebo-Controlled Trial.
Abstract Methods: Eighty-eight patients undergoing THA were randomized to receive 0.33% ropivacaine (Group QLB, n = 44) or saline (Group Con, n = 44) for QL3 block. Spinal anesthesia was then performed. Pain intensity was assessed using the visual analog scale (0: no pain to 10: worst possible pain). The primary outcome was pain scores recorded at rest at 3, 6, 12, 24, 36, and 48 h and on standing and walking at 24, 36, and 48 h postoperatively. Secondary outcomes were analgesic consumption, side effects, the 10-meter walking speed on day 6, and patient satisfaction after ...
Source: Pain Research and Management - April 8, 2020 Category: Anesthesiology Authors: He J, Zhang L, He WY, Li DL, Zheng XQ, Liu QX, Wang HB Tags: Pain Res Manag Source Type: research

Meta-Analysis of Integrated Therapeutic Methods in Noninvasive Lower Back Pain Therapy (LBP): The Role of Interdisciplinary Functional Diagnostics.
Conclusions: Lower back pain is a serious health problem, and this review article will help educate physicians and physiotherapists dealing with LBP in the options of evidence-based treatment. Ultimately, the article introduces and postulates the need to systematize therapeutic procedures in LBP therapy, with a long-term perspective. PMID: 32256908 [PubMed - as supplied by publisher] (Source: Pain Research and Management)
Source: Pain Research and Management - April 8, 2020 Category: Anesthesiology Authors: Bitenc-Jasiejko A, Konior K, Lietz-Kijak D Tags: Pain Res Manag Source Type: research

Is Acupuncture Another Good Choice for Physicians in the Treatment of Chronic Prostatitis/Chronic Pelvic Pain Syndrome? Review of the Latest Literature.
In conclusion, the evidence suggests that acupuncture may be an effective intervention for patients with CP/CPPS. However, due to the heterogeneity of the methods and high risk of bias, we cannot draw definitive conclusions about the entity of the acupuncture's effect on alleviating the symptoms of CP/CPPS. The adverse events of acupuncture are mild and rare. PMID: 32256909 [PubMed - as supplied by publisher] (Source: Pain Research and Management)
Source: Pain Research and Management - April 8, 2020 Category: Anesthesiology Authors: Li J, Dong L, Yan X, Liu X, Li Y, Yu X, Chang D Tags: Pain Res Manag Source Type: research

Knowledge and Attitude towards Pain Management among Nurses Working at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia.
Conclusion and Recommendation. This study revealed that nurses working at University of Gondar hospital had good knowledge and a lower level of attitude towards pain management than those reported in previous studies. Thus, the situation demands various educational and quality improvement initiatives that could enhance the nurse's knowledge and attitude in the area of pain management. PMID: 32256910 [PubMed - as supplied by publisher] (Source: Pain Research and Management)
Source: Pain Research and Management - April 8, 2020 Category: Anesthesiology Authors: Liyew B, Dejen Tilahun A, Habtie Bayu N, Kassew T Tags: Pain Res Manag Source Type: research

Basic and Clinical Advances in the Diagnosis and Management of Migraine.
PMID: 32256911 [PubMed - as supplied by publisher] (Source: Pain Research and Management)
Source: Pain Research and Management - April 8, 2020 Category: Anesthesiology Authors: Shi X, Di W, Wieczorek A Tags: Pain Res Manag Source Type: research

Efficacy Analysis of Percutaneous Endoscopic Lumbar Discectomy Combined with PEEK Rods for Giant Lumbar Disc Herniation: A Randomized Controlled Study.
This study describes a randomized controlled trial that assesses percutaneous endoscopic lumbar discectomy (PELD) combined with a polyetheretherketone (PEEK) rod in patients with GLDH (herniation affecting 50% of the sagittal diameter of the spinal canal) and reports the 2-year follow-up outcome. Methods: In all, 243 patients were randomly assigned to undergo PELD or PELD combined with a PEEK rod by generating random numbers with a random number generator. Clinical outcome data, including the numerical rating scale (NRS), were used to assess the patients' back and leg pain, while the Oswestry Disability Index (ODI) wa...
Source: Pain Research and Management - March 29, 2020 Category: Anesthesiology Authors: Gao X, Tang K, Xia Y, Zhang X, Wang K, Yan Z, Du Y, Chen L Tags: Pain Res Manag Source Type: research

A Bibliometric Analysis of Nonspecific Low Back Pain Research.
Conclusion: This study offers insights into the trend of NSLBP to determine major research countries and institutions, core journals, pivotal authors, overall development tendency, hot topics, and research frontiers. Moreover, it will help researchers extract hidden valuable information for further study. PMID: 32215136 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - March 29, 2020 Category: Anesthesiology Authors: Weng LM, Zheng YL, Peng MS, Chang TT, Wu B, Wang XQ Tags: Pain Res Manag Source Type: research

Local Infiltration Analgesia with Ropivacaine Improves Postoperative Pain Control in Ankle Fracture Patients: A Retrospective Cohort Study.
Abstract Purpose: The study aimed at investigating the effect of local infiltration analgesia (LIA) with ropivacaine on postoperative analgesia for patients undergoing ankle fracture surgery. Methods: Consecutive patients were retrospectively included and analysed according to their medical records from July 2014 to August 2018 in a tertiary hospital. Inclusion criteria were patients undergoing open reduction and internal fixation (ORIF) for ankle fractures under general anaesthesia. Moreover, patients should have received intravenous patient-controlled analgesia (iPCA) or LIA + iPCA for postope...
Source: Pain Research and Management - March 29, 2020 Category: Anesthesiology Authors: Li BL, Liu X, Cui L, Zhang W, Pang H, Wang M, Wang HQ Tags: Pain Res Manag Source Type: research

VGLUT2/Cdk5/p25 Signaling Pathway Contributed to Inflammatory Pain by Complete Freund's Adjuvant.
Abstract Vesicular glutamate transporter type 2 (VGLUT2) is known to play an important role in mediating heat hyperalgesia induced by inflammation. However, the underlying mechanism for this activity is poorly understood. Cyclin-dependent kinase 5 (Cdk5), serving as a key regulator in modulating release of glutamate, acted a key player in the formation of heat hyperalgesia of inflammatory pain. However, it remains unknown whether there is a bridge between Cdk5 and VGLUT2 for mediating inflammatory pain. Therefore, we designed the experiment to determine whether VGLUT2 signaling pathway is involved in inflammatory ...
Source: Pain Research and Management - March 21, 2020 Category: Anesthesiology Authors: Tang Y, Peng Z, Tao S, Sun J, Wang W, Guo X, Liu G, Luo X, Chen Y, Shen Y, Ma H, Xu P, Li Q, Zhang H, Feng Z Tags: Pain Res Manag Source Type: research

Effects of Supraorbital Foramen Variations on the Treatment Efficacy of Radiofrequency Therapy for V1 Trigeminal Neuralgia: A Retrospective Study.
Abstract Background: Primary V1 trigeminal neuralgia is a common refractory neuralgia in clinical practice, lacking effective treatments. Radiofrequency therapy has certain treatment efficacy, but its long-term efficacy remained poor and the disease might relapse. Objective: To compare the effects of different types of supraorbital foramen variations on the treatment efficacy of radiofrequency therapy for V1 trigeminal neuralgia. Methods: Data of 54 patients with V1 trigeminal neuralgia who underwent treatment in the First Hospital of Jiaxing, Zhejiang, were retrospectively analyzed. All these patients r...
Source: Pain Research and Management - March 19, 2020 Category: Anesthesiology Authors: Xie K, Liu S, Huang B, Yao M Tags: Pain Res Manag Source Type: research

Prednisone for Acute Complex Regional Pain Syndrome: A Retrospective Cohort Study.
The objective of this study was to evaluate prednisone effectiveness on complex regional pain syndrome (CRPS) features in a community-based outpatient rehabilitation setting. Design: A single-centre, retrospective inception cohort design was used. Inclusion criteria were CRPS diagnosis according to the Budapest criteria, involvement of multiple joints, treatment with prednisone, and duration of symptoms less than one year. Typical prednisone treatment was 28-day taper regimen with 60 mg. Patient symptoms and signs were compared before and after treatment. Results: There were 39 patients who met inclusion c...
Source: Pain Research and Management - March 19, 2020 Category: Anesthesiology Authors: Jamroz A, Berger M, Winston P Tags: Pain Res Manag Source Type: research

Predicting Acute Postoperative Pain Trajectories and Long-Term Outcomes of Adolescents after Spinal Fusion Surgery.
Discussion. Preoperative assessment and analyzing the progression of pain in the acute postoperative period can help identify those at risk of negative long-term outcomes after surgery. PMID: 32184913 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - March 19, 2020 Category: Anesthesiology Authors: Ocay DD, Li MMJ, Ingelmo P, Ouellet JA, Pagé MG, Ferland CE Tags: Pain Res Manag Source Type: research

DNA Methylation May be Involved in the Analgesic Effect of Hyperbaric Oxygen via Regulating FUNDC1.
Conclusion: Our findings suggest that DNA methylation is involved in the analgesic effect of HBO via the regulation of FUNDC1. PMID: 32148597 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - March 11, 2020 Category: Anesthesiology Authors: Liu K, Wu H, Gao R, Han G Tags: Pain Res Manag Source Type: research

Self-Compassion Demonstrating a Dual Relationship with Pain Dependent on High-Frequency Heart Rate Variability.
Abstract One previous study indicated the significance of trait self-compassion in psychological well-being and adjustment in people with chronic pain. Higher-frequency heart rate variability (HF-HRV) was found to be closely associated with self-compassion and pain coping. The current study was therefore designed to investigate the relationship between self-compassion and experimental pain as well as the impact of HF-HRV. Sixty healthy participants provided self-reported self-compassion and underwent a cold pain protocol during which HF-HRV was evaluated. Results demonstrated a dual relationship between self-compa...
Source: Pain Research and Management - March 11, 2020 Category: Anesthesiology Authors: Tian S, Luo X, Che X, Xu G Tags: Pain Res Manag Source Type: research

Procedural Treatments for Knee Osteoarthritis: A Review of Current Injectable Therapies.
Abstract Knee osteoarthritis is a common painful degenerative condition affecting the aging Canadian population. In addition to pain and disability, osteoarthritis is associated with depression, comorbid conditions such as diabetes, and increased caregiver burden. It is predicted to cost the Canadian healthcare system $7.6 billion dollars by 2031. Despite its high cost and prevalence, controversy persists in the medical community regarding optimal therapies to treat knee osteoarthritis. A variety of medications like nonsteroidal anti-inflammatories and opioids can cause severe side effects with limited benefits. T...
Source: Pain Research and Management - March 11, 2020 Category: Anesthesiology Authors: Billesberger LM, Fisher KM, Qadri YJ, Boortz-Marx RL Tags: Pain Res Manag Source Type: research

Final Year Nursing Students' Knowledge and Attitudes regarding Children's Pain.
Abstract Pain is one of the commonest reasons why children visit the hospital. Inadequately treated pain in children can negatively affect their physical, psychological, and social well-being; it also places financial burden on families of affected children and healthcare systems in general. Considering the eventual suffering of vulnerable children and their families if nursing students are insufficiently educated and ill-prepared, the current study aimed at assessing final year nursing student's knowledge and attitudes pertaining to pediatric pain. A descriptive cross-sectional study was conducted among 100 final...
Source: Pain Research and Management - March 11, 2020 Category: Anesthesiology Authors: Kusi Amponsah A, Kyei-Dompim J, Kyei EF, Oduro E, Afaya RA, Ahoto CK Tags: Pain Res Manag Source Type: research

Perceptions and Impact of the 2017 Canadian Guideline for Opioid Therapy and Chronic Noncancer Pain: A Cross-Sectional Study of Canadian Physicians.
Conclusion: There was high awareness of the 2017 Canadian opioid guideline among respondents, and preliminary evidence that recommendations have changed practice to better align with the evidence. Ongoing education is required to avoid the misunderstanding that opioid tapering is mandatory, and research to identify effective strategies to manage chronic noncancer pain is urgently needed. PMID: 32148601 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - March 11, 2020 Category: Anesthesiology Authors: Busse JW, Douglas J, Chauhan TS, Kobeissi B, Blackmer J Tags: Pain Res Manag Source Type: research

Systematic Administration of B Vitamins Alleviates Diabetic Pain and Inhibits Associated Expression of P2X3 and TRPV1 in Dorsal Root Ganglion Neurons and Proinflammatory Cytokines in Spinal Cord in Rats.
Conclusions: B-vitamin treatment can greatly suppress chronic DNP and DNP-associated increased activities of P2X3 and TRPV1 in DRG and the spinal proinflammatory cytokines, which may contribute to the pathogenesis of DNP. Systematic administration of B vitamins can be a strategy for DNP management in clinic. PMID: 32104520 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - February 28, 2020 Category: Anesthesiology Authors: He DD, Gao Y, Wang S, Xie Z, Song XJ Tags: Pain Res Manag Source Type: research

Current and Emerging Pharmacotherapy for Fibromyalgia.
Abstract Introduction. Fibromyalgia syndrome (FMS) is a pain disorder with an estimated prevalence of 1-5%. It is associated with a variety of somatic and psychological disorders. Its exact pathogenesis is still unclear but is involved with neural oversensitization and decreased conditioned pain modulation (CPM), combined with cognitive dysfunction, memory impairment, and altered information processing. Connectivity between brain areas involved in pain processing, alertness, and cognition is increased in the syndrome, making its pharmacologic therapy complex. Only three drugs, pregabalin, duloxetine, and milnacipr...
Source: Pain Research and Management - February 28, 2020 Category: Anesthesiology Authors: Tzadok R, Ablin JN Tags: Pain Res Manag Source Type: research

Role of Oxycodone Hydrochloride in Treating Radiotherapy-Related Pain.
Abstract Radiotherapy is commonly used to treat cancer patients. Besides the curable effect, radiotherapy also could relieve the pain of cancer patients. However, cancer pain is gradually alleviated about two weeks after radiotherapy. In addition, cancer patients who receive radiotherapy may also suffer from pain flare or radiotherapy-induced side effects such as radiation esophagitis, enteritis, and mucositis. Pain control is reported to be inadequate during the whole course of radiotherapy (before, during, and after radiotherapy), and quality of life is seriously affected. Hence, radiotherapy is suggested to be ...
Source: Pain Research and Management - February 25, 2020 Category: Anesthesiology Authors: Wang Y, Xing L Tags: Pain Res Manag Source Type: research

Chronic Pain following Chest Trauma: Prevalence, Associated Factors, and Psychosocial Impact.
Conclusion: CP following chest trauma is frequent and severe requiring preventive measures such as high risk patients screening, better management of acute pain, and a multidisciplinary approach for patients with diagnosed CP. PMID: 32071652 [PubMed - in process] (Source: Pain Research and Management)
Source: Pain Research and Management - February 21, 2020 Category: Anesthesiology Authors: Kahloul M, Kacem I, Sboui MM, El Maalel O, Daami H, Hafsia M, Limam M, Aissa S, Ben Kbaier I, Mrizak N, Chaouch A, Naija W Tags: Pain Res Manag Source Type: research

Nursing-Related Barriers to Children's Pain Management at Selected Hospitals in Ghana: A Descriptive Qualitative Study.
Abstract Staff shortages, deficient knowledge, inappropriate attitudes, demanding workloads, analgesic shortages, and low prioritization of pain management have been identified in earlier studies as the nursing-related barriers to optimal children's pain management. These studies have mainly been undertaken in developed countries, which have different healthcare dynamics than those in developing countries. The current study, therefore, sought to identify and understand the nursing-related barriers to children's pain management in the Ghanaian context. A descriptive qualitative study was conducted among 28 purposiv...
Source: Pain Research and Management - February 14, 2020 Category: Anesthesiology Authors: Kusi Amponsah A, Kyei EF, Agyemang JB, Boakye H, Kyei-Dompim J, Ahoto CK, Oduro E Tags: Pain Res Manag Source Type: research

Clinical Rehabilitation Effect of Postoperative Lower-Limb Training on the Patients Undergoing OLIF Surgery: A Retrospective Study.
In this study, it was aimed to investigate the clinical rehabilitation effect of lower-limb training on the patients that undergo oblique lumbar interbody fusion (OLIF) procedures. Methods: The eligible participants undergoing OLIF procedures between 01/2017 and 07/2019 were identified. All the patients underwent one-segment fusion operation (L3-4 or L4-5). Based on whether the participants received postoperative rehabilitation training, they were divided into two groups: intervention group and control group. Postoperatively, the participants in the intervention group were trained with lower-extremity rehabilitation e...
Source: Pain Research and Management - February 5, 2020 Category: Anesthesiology Authors: Wang H, Huo Y, Zhao Y, Zhang B, Yang D, Yang S, Ding W Tags: Pain Res Manag Source Type: research

Comparison of Transcutaneous Electric Nerve Stimulation (TENS) and Microcurrent Nerve Stimulation (MENS) in the Management of Masticatory Muscle Pain: A Comparative Study.
Conclusion: In the present study, it was found that TENS and MENS are equally effective in improving the functional mouth opening. MENS showed better and immediate effect in relief of pain. Microcurrent also has the advantage of being subthreshold, and hence the side effects such as tingling sensation and paresthesia seen to occur in some patients following TENS are absent. TENS and MENS can be considered as the first line of treatment in patients with acute and chronic masticatory muscle pain and also as an effective treatment option in cases of functional mouth opening. PMID: 31871515 [PubMed - in process] (Source: ...
Source: Pain Research and Management - December 26, 2019 Category: Anesthesiology Authors: Saranya B, Ahmed J, Shenoy N, Ongole R, Sujir N, Natarajan S Tags: Pain Res Manag Source Type: research