Haemophilus Influenzae (Hib) Research Haemophilus Influenzae (Hib) RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Rare serotype c Haemophilus influenzae invasive isolate: characterization of the first case in Portugal
We report for the first time in Portugal a serotype cHaemophilus influenzae isolated from an adult, with HIV-1 infection. Whole-genome sequencing characterized the isolate as clonal complex ST-7, albeit with a novel MLST (ST2754) due to a uniqueatpG profile. Integration of this genome with other availableH. influenzae serotype c genomes from PubMLST revealed its overall genetic distinctiveness, with the closest related isolate being identified in France in 2020. This surveillance study, involving collaboration among hospitals and reference laboratory, successfully contributed to the identification and characterization of t...
Source: European Journal of Clinical Microbiology and Infectious Diseases - February 9, 2024 Category: Microbiology Source Type: research

Haemophilus influenzae infection in pregnancy and its adverse fetal outcomes related, about a case
Introduction and aims of the study: Haemophilus influenzae (Hi) is a pleomorphic gram-negative rod that commonly colonizes and infects human respiratory tract. It can be divided in typeable and nontypeable strains. Among typeable strains, H. influenzaeserotype b (Hib) is the most virulent. In areas such as our country, Hib vaccination has been included in the recommended immunization schedule, so its prevalence as declined favoring nontypeable Hi (usually less virulent). (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 1, 2024 Category: OBGYN Authors: Sofia Pedrosa de Moura, Susana Saraiva, Carolina Carneiro, Margarida Brand ão, Catia Rasteiro Source Type: research

Otitis media: recent advances in otitis media vaccine development and model systems
Otitis media is an inflammatory disorder of the middle ear caused by airways-associated bacterial or viral infections. It is one of the most common childhood infections as globally more than 80% of children are diagnosed with acute otitis media by 3 years of age and it is a common reason for doctor’s visits, antibiotics prescriptions, and surgery among children. Otitis media is a multifactorial disease with various genetic, immunologic, infectious, and environmental factors predisposing children to develop ear infections. Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis are the most common cu...
Source: Frontiers in Microbiology - January 24, 2024 Category: Microbiology Source Type: research

Is it in their eyes? Correlation between microorganisms isolated from bronchial aspirates and conjunctival swabs in a Pediatric Intensive Care Unit
CONCLUSIONS: Our study demonstrates a strong concordance between the isolated microorganisms from both samples in patients presenting clear symptoms of clinical conjunctivitis. These findings provide a basis for future prospective studies that may leverage conjunctival swabs as a predictive tool for identifying microorganisms involved in respiratory infections.PMID:38258553 | DOI:10.37201/req/116.2023 (Source: Revista Espanola de Quimioterapia)
Source: Revista Espanola de Quimioterapia - January 23, 2024 Category: Drugs & Pharmacology Authors: J Ligero-L ópez L Escosa-Garc ía C Sch üffelmann-Gutiérrez M Laplaza-Gonz ález M I Quiles-Melero F Moreno-Ramos F Baquero-Artigao J Cacho-Calvo E Cendejas-Bueno Source Type: research

The epidemiology and the pathogen distribution of pediatric dacryocystitis in Chinese population 2017 –2022
ConclusionsDacryocystitis in children is significantly associated with age characteristics and infection-related pathogens, and infection prevention and control can help reduce the infection of related pathogens and the increase of new drug-resistant strains. Close monitoring of changes in pathogen distribution in ocular secretion cultures can help in early intervention and treatment of infectious dacryocystitis. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - January 22, 2024 Category: Pediatrics Source Type: research

Bacterial colonisation of the airway in neonates and risk of asthma and allergy until age 18 years
Extract Asthma is believed to originate in early life [1–3]. Earlier prospective cohort studies have shown that the airway and gut microbiome plays an important role in the risk of childhood asthma [3–9]. In the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC2000) birth cohort, neonatal airway colonisation (at 1 month) with Streptococcus pneumoniae, Haemophilus influenzae and/or Moraxella catarrhalis was associated with an increased risk of asthma by age 5 years. Airway colonisation was furthermore associated with increased frequency of lower respiratory tract infections, positive bronch...
Source: European Respiratory Journal - January 18, 2024 Category: Respiratory Medicine Authors: Sunde, R. B., Thorsen, J., Kim, M., Schoos, A.-M. M., Stokholm, J., Bonnelykke, K., Bisgaard, H., Chawes, B. Tags: Asthma and allergy Original Articles: Asthma Source Type: research

Early-life airway microbiome and childhood asthma development
Extract Asthma is the most common chronic respiratory disease among children, with approximately 10–15% of children affected in the world [1]. Epidemiological research has identified many risk factors for childhood asthma, including genetic factors [2–7], respiratory infections [8–10], personal and family history of allergic diseases [11], and environmental (e.g. air pollution, respiratory viruses) and lifestyle (e.g. nutrition, physical activity, obesity) factors [12, 13]. While experts agree on the early life origins of most childhood asthma [14], it is still unknown whether early life risk factors will...
Source: European Respiratory Journal - January 18, 2024 Category: Respiratory Medicine Authors: Zhu, Z. Tags: Editorials Source Type: research

Efficacy and Prolonged Safety of Haemophilus influenzae Type B Conjugate Vaccines
CONCLUSION: The Hib conjugate vaccination has shown to be extremely effective when administered to the entire population. However, changes to the immunisation protocol appear to be required in order to effectively manage invasive Hib illness.PMID:38231056 | DOI:10.2174/0118715265269877231117070051 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - January 17, 2024 Category: Infectious Diseases Authors: Nishita Tripathi Sayali Mukherjee Source Type: research

The Increase in Invasive Bacterial Infections With Respiratory Transmission in Germany, 2022/2023
CONCLUSION: The reason for the marked rise in invasive bacterial infections may be an increased circulation of respiratory pathogens and elevated susceptibility in the population after relaxation of the measures taken to prevent COVID-19 infection. Coinfections with respiratory viruses may have reinforced this effect. We recommend continuous surveillance, preventive measures such as raising awareness about invasive bacterial diseases, and vaccination as recommended by the German Standing Committee on Vaccinations (STIKO).PMID:38229497 | DOI:10.3238/arztebl.m2023.0261 (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - January 17, 2024 Category: General Medicine Authors: Regina Singer Muna Abu Sin Tobias Tenenbaum Nicole Toepfner Reinhard Berner Silke Buda Johanna Schlaberg Viktoria Sch önfeld Ulrich Reinacher Mark van der Linden Heike Claus Thi ên Trí Lâm Marc Schneider Ines Noll Sebastian Haller Anja von Laer Source Type: research

Gene polymorphisms of IL-17A and bacterial meningitis in Angolan children
This study suggests an association of IL-17A genetic variations with susceptibility and outcome of bacterial meningitis in Angolan children.PMID:38228216 | DOI:10.1016/j.meegid.2024.105553 (Source: Infection, Genetics and Evolution)
Source: Infection, Genetics and Evolution - January 16, 2024 Category: Genetics & Stem Cells Authors: Johanna Ter äsjärvi Elina Tenhu Manuel Leite Cruzeiro Okko Savonius Emilie Rugemalira Qiushui He Tuula Pelkonen Source Type: research

Pediatric central nervous system infections in the Amazon: clinical and laboratory profiles
CONCLUSION: This study shows the presence of important vaccine-preventable pathogens, and different families of viruses causing CNS infections in the pediatric patients of Manaus.PMID:38186717 | PMC:PMC10768178 | DOI:10.3389/fpubh.2023.1329091 (Source: Herpes)
Source: Herpes - January 8, 2024 Category: Infectious Diseases Authors: Eveny Perlize Melo Marinho Ewerton da Silva Ferreira Caio Cesar Leiva Bastos Barrionuevo Sabrina Ara újo Melo Jady Shayenne Mota Cordeiro Sergio Damasceno Pinto Rossicleia Lins Monte Valderjane Apr ígio da Silva Yasmin Ferreira Martins Monique Freire Re Source Type: research

Understanding the effects of Haemophilus influenzae colonization on bronchiectasis: a retrospective cohort study
This study aimed to elucidate ... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - January 2, 2024 Category: Respiratory Medicine Authors: Seo-Hee Yang, Myung Jin Song, Yeon Wook Kim, Byoung Soo Kwon, Sung Yoon Lim, Yeon-Joo Lee, Jong Sun Park, Young-Jae Cho, Jae Ho Lee, Choon-Taek Lee and Hyung-Jun Kim Tags: Research Source Type: research

Bacterial Meningitis Caused by Haemophilus influenzae Type F Diagnosed Using Next-Generation Sequencing
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - December 28, 2023 Category: Pediatrics Source Type: research

Nasopharyngeal carriage and antibiotic susceptibility patterns of Sstreptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and Staphylococcus aureus among urban Ugandan children post-PCV10 introduction: a cross-sectional study
In 2013, Uganda introduced the PCV10 pneumococcal vaccine and it is given to children at 6, 10 and 14 weeks after birth. Carriage prevalence studies post PCV10-introduction are necessary for monitoring the impact of vaccination and trends in antibiotic resistance. Here, we studied carriage/antibiotic resistance of Streptococcus pneumoniae (pneumococcus),Haemophilus influenzae, Moraxella catarrhalis, andStaphylococcus aureus isolated from 194 children at the Mulago Assessment Centre clinic in Kampala-Uganda, 5 years post-PCV10 introduction. Almost all the children were vaccinated with PCV10 (98.5%, 191/194). The overall car...
Source: African Health Sciences - December 27, 2023 Category: African Health Authors: Nshimiyimana Thadd ée , Najjuka Christine Florence , Nalwanga Winnie , Katende George , Kateete David Patrick Source Type: research

Imipenem heteroresistance but not tolerance in Haemophilus influenzae during chronic lung infection associated with chronic obstructive pulmonary disease
In this study, we assessed imipenem resistance, heteroresistance and tolerance in a previously sequenced longitudinal collection of H. influenzae COPD respiratory isolates. The use of Etest, disc diffusion, population analysis profiling, tolerance disc (TD)-test methods, and susceptibility breakpoint criteria when available, showed a significant proportion of imipenem heteroresistance with differences in terms of degree among strains, absence of imipenem tolerance, and no specific trends among serial and clonally related strains could be established. Analysis of allelic variation in the ftsI, acrA, acrB, and acrR genes ren...
Source: Frontiers in Microbiology - December 20, 2023 Category: Microbiology Source Type: research