Etiology of Meningoencephalitis in children aged less than 5 years
CONCLUSION: We identified the etiological agents in 50/130 (38.5%) suspected ME cases in children less than 5 years of age, using molecular and ELISA-based diagnostic methods. The four most common pathogens detected were JEV, adenovirus, influenza virus, and dengue virus.PMID:38394398 | DOI:10.4103/ijpm.ijpm_60_23 (Source: Herpes)
Source: Herpes - February 23, 2024 Category: Infectious Diseases Authors: Vivek K Mishra Tanzeela Khan Amar Jeet Om Prakash None Chandrakanta Ashish K Srivastava Sangram Singh Neelam Pathak Amita Jain Source Type: research

Etiology of Meningoencephalitis in children aged less than 5 years
CONCLUSION: We identified the etiological agents in 50/130 (38.5%) suspected ME cases in children less than 5 years of age, using molecular and ELISA-based diagnostic methods. The four most common pathogens detected were JEV, adenovirus, influenza virus, and dengue virus.PMID:38394398 | DOI:10.4103/ijpm.ijpm_60_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - February 23, 2024 Category: Pathology Authors: Vivek K Mishra Tanzeela Khan Amar Jeet Om Prakash None Chandrakanta Ashish K Srivastava Sangram Singh Neelam Pathak Amita Jain Source Type: research

Etiology of Meningoencephalitis in children aged less than 5 years
CONCLUSION: We identified the etiological agents in 50/130 (38.5%) suspected ME cases in children less than 5 years of age, using molecular and ELISA-based diagnostic methods. The four most common pathogens detected were JEV, adenovirus, influenza virus, and dengue virus.PMID:38394398 | DOI:10.4103/ijpm.ijpm_60_23 (Source: Herpes)
Source: Herpes - February 23, 2024 Category: Infectious Diseases Authors: Vivek K Mishra Tanzeela Khan Amar Jeet Om Prakash None Chandrakanta Ashish K Srivastava Sangram Singh Neelam Pathak Amita Jain Source Type: research

Etiology of Meningoencephalitis in children aged less than 5 years
CONCLUSION: We identified the etiological agents in 50/130 (38.5%) suspected ME cases in children less than 5 years of age, using molecular and ELISA-based diagnostic methods. The four most common pathogens detected were JEV, adenovirus, influenza virus, and dengue virus.PMID:38394398 | DOI:10.4103/ijpm.ijpm_60_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - February 23, 2024 Category: Pathology Authors: Vivek K Mishra Tanzeela Khan Amar Jeet Om Prakash None Chandrakanta Ashish K Srivastava Sangram Singh Neelam Pathak Amita Jain Source Type: research

Etiology of Meningoencephalitis in children aged less than 5 years
CONCLUSION: We identified the etiological agents in 50/130 (38.5%) suspected ME cases in children less than 5 years of age, using molecular and ELISA-based diagnostic methods. The four most common pathogens detected were JEV, adenovirus, influenza virus, and dengue virus.PMID:38394398 | DOI:10.4103/ijpm.ijpm_60_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - February 23, 2024 Category: Pathology Authors: Vivek K Mishra Tanzeela Khan Amar Jeet Om Prakash None Chandrakanta Ashish K Srivastava Sangram Singh Neelam Pathak Amita Jain Source Type: research

Etiology of Meningoencephalitis in children aged less than 5 years
CONCLUSION: We identified the etiological agents in 50/130 (38.5%) suspected ME cases in children less than 5 years of age, using molecular and ELISA-based diagnostic methods. The four most common pathogens detected were JEV, adenovirus, influenza virus, and dengue virus.PMID:38394398 | DOI:10.4103/ijpm.ijpm_60_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - February 23, 2024 Category: Pathology Authors: Vivek K Mishra Tanzeela Khan Amar Jeet Om Prakash None Chandrakanta Ashish K Srivastava Sangram Singh Neelam Pathak Amita Jain Source Type: research

Etiology of Meningoencephalitis in children aged less than 5 years
CONCLUSION: We identified the etiological agents in 50/130 (38.5%) suspected ME cases in children less than 5 years of age, using molecular and ELISA-based diagnostic methods. The four most common pathogens detected were JEV, adenovirus, influenza virus, and dengue virus.PMID:38394398 | DOI:10.4103/ijpm.ijpm_60_23 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - February 23, 2024 Category: Pathology Authors: Vivek K Mishra Tanzeela Khan Amar Jeet Om Prakash None Chandrakanta Ashish K Srivastava Sangram Singh Neelam Pathak Amita Jain Source Type: research

Epidemiology and Clinical Outcomes of Bacterial Meningitis in Children and Adults in Low- and Middle-Income Countries
AbstractPurpose of ReviewDespite the availability of effective vaccines against the three primary pathogens (Streptococcus pneumoniae,Haemophilus influenzae type b, andNeisseria meningitidis) that cause bacterial meningitis, this condition remains a significant cause of morbidity, neurologic sequelae, and mortality among children and adults living in low-income and middle-income countries.Recent FindingsBacterial meningitis represents a significant public health challenge for national and global health systems. Since vaccine-preventable meningitis remains highly prevalent in low-income and middle-income countries, the Worl...
Source: Current Tropical Medicine Reports - February 22, 2024 Category: Tropical Medicine Source Type: research

A retrospective observational study of 1000 consecutive patients tested with the FilmArray ® Meningitis/Encephalitis panel: clinical diagnosis at discharge and microbiological findings
In this study, we investigated performance of FAME-p compared to comparator assays (CA), and for the first time, clinical diagnosis at discharge (CDD). 1000 consecutive patients with a cerebrospinal fluid (CSF) sample analyzed with FAME-p were identified. As CA, culture, polymerase chain reaction and cryptococcal antigen test were used. Medical records of patients were obtained. A CDD of CNS infection was made in 139 of 1000 CSF samples. FAME-p was positive in 66 samples with 44 viral and 22 bacterial agents. Thirteen FAME-p findings were not confirmed by CA, with four discrepant results remaining after comparison with the...
Source: Herpes - February 18, 2024 Category: Infectious Diseases Authors: Torgny Sunnerhagen Johan Wid én Sahar Handhal G ülşen Özkaya Şahin Source Type: research

Adenovirus and < em > Mycoplasma pneumoniae < /em > co-infection as a risk factor for severe community-acquired pneumonia in children
CONCLUSIONS: AdV and MP were dominant pathogens in children with severe CAP. AdV and MP infection predisposed each other to develop severe illness. AdV-MP co-infection may lead to severe pneumonia.PMID:38357505 | PMC:PMC10864498 | DOI:10.3389/fped.2024.1337786 (Source: Adv Data)
Source: Adv Data - February 15, 2024 Category: Epidemiology Authors: Qihong Chen Lihua Lin Ning Zhang Yungang Yang Source Type: research

Adenovirus and < em > Mycoplasma pneumoniae < /em > co-infection as a risk factor for severe community-acquired pneumonia in children
CONCLUSIONS: AdV and MP were dominant pathogens in children with severe CAP. AdV and MP infection predisposed each other to develop severe illness. AdV-MP co-infection may lead to severe pneumonia.PMID:38357505 | PMC:PMC10864498 | DOI:10.3389/fped.2024.1337786 (Source: Adv Data)
Source: Adv Data - February 15, 2024 Category: Epidemiology Authors: Qihong Chen Lihua Lin Ning Zhang Yungang Yang Source Type: research

Correction: Understanding the effects of Haemophilus influenzae colonization on bronchiectasis: a retrospective cohort study
(Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - February 13, 2024 Category: Respiratory Medicine Authors: Seo-Hee Yang, Myung Jin Song, Yeon Wook Kim, Byoung Soo Kwon, Sung Yoon Lim, Yeon-Joo Lee, Jong Sun Park, Young-Jae Cho, Jae Ho Lee, Choon-Taek Lee and Hyung-Jun Kim Tags: Correction Source Type: research

Bacterial small RNAs may mediate immune response differences seen in respiratory syncytial virus versus rhinovirus bronchiolitis
Bronchiolitis, a viral lower respiratory infection, is the leading cause of infant hospitalization, which is associated with an increased risk for developing asthma later in life. Bronchiolitis can be caused by several respiratory viruses, such as respiratory syncytial virus (RSV), rhinovirus (RV), and others. It can also be caused by a solo infection (e.g., RSV- or RV-only bronchiolitis) or co-infection with two or more viruses. Studies have shown viral etiology-related differences between RSV- and RV-only bronchiolitis in the immune response, human microRNA (miRNA) profiles, and dominance of certain airway microbiome con...
Source: Frontiers in Immunology - February 12, 2024 Category: Allergy & Immunology Source Type: research

Comparison of the adherence of nontypeable haemophilus influenzae to lung epithelial cells
Nontypeable Haemophilus influenzae (NTHi) plays an important role in respiratory tract infections, and adherence to lung epithelial cells is the first step in lung infections. To explore the role of NTHi in child... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - February 12, 2024 Category: Infectious Diseases Authors: Yuwei Rong, Zihao Liu, Heping Wang and Zuguo Zhao Tags: Research Source Type: research

Diagnostic Accuracy of Cerebrospinal Fluid Multiplex Polymerase Chain Reaction Panel Testing in Patients With Suspected Central Nervous System Infections: A Multi-Center Study in the United Arab Emirates
Conclusion CSF mPCR panel is a highly sensitive and specific diagnostic tool for the diagnosis of CNS infections among all age groups in the UAE. Routine use of CSF mPCR panels can decrease healthcare costs by reducing the length of stay and can also aid antibiotic stewardship efforts by reducing antibiotic overuse in patients with viral CSF infections. CSF culture and mPCR complement each other by identifying CNS pathogens in patients with prior antibiotic exposure who would otherwise be missed if relying on CSF culture alone. However, concomitant CSF culture samples should be sent to avoid missing unusual CNS pathogens.P...
Source: Herpes - February 9, 2024 Category: Infectious Diseases Authors: Yousra Ghoweba Seyed Ali Safizadeh Shabestari Zainab A Malik Source Type: research