Immunogenicity and safety of concomitant administration of the sabin-strain-based inactivated poliovirus vaccine, the diphtheria-tetanus-acellular pertussis vaccine and measles-mumps-rubella vaccine to healthy infants aged 18 months in China
The COVID-19 pandemic had a profound impact on China's healthcare system, causing a noticeable decline in vaccine coverage and a subsequent resurgence of vaccine-preventable diseases (VPDs) [1 –4]. Immunization programs are intricate, requiring children to receive multiple vaccines concurrently. As new non-immunization programming vaccines (such as Haemophilus influenzae type b vaccine (Hib), rabies vaccine, and influenza vaccine (InfV), are available in China, but are usually paid for out-of-pocket, as they are included in neither the EPI system nor government health insurance) are introduced, the number of vaccines adm...
Source: International Journal of Infectious Diseases - October 11, 2023 Category: Infectious Diseases Authors: Yan Xu, Haiping Chen, Binbing Wang, Xiaoping Zhu, Linyun Luo, Shengyi Wang, Yanhui Xiao, Hui Wang, Rui Ma, Shaoxiang Liu, Long Yan, Xiuling Li, Dandan Chen, Ying Su, Yu Chai, Jun Fu, Xiaoying Mao, Jie Cao, Pufei Sun, Fenyang Tang, Xiang Sun, Zhiguo Wang, Source Type: research

Evaluation of the BioFire ® FilmArray® Pneumonia < em > plus < /em > Panel for Detecting Bacterial Etiological Agents of Lower Respiratory Tract Infections in an Oncologic Hospital. Comparison with Conventional Culture Method
Pol J Microbiol. 2023 Oct 10. doi: 10.33073/pjm-2023-035. Online ahead of print.ABSTRACTConventional methods used to determine pneumonia pathogens are characterized by low sensitivity and long turnaround times. Introducing new tests with better parameters in patients at higher risk of infections is highly anticipated. The results of the conventional quantitative culture method (CM) in determining the bacterial etiology of pneumonia were compared with the results of the Pneumonia plus Panel test (PNP; BioFire® Diagnostics, USA) in 79 samples of bronchoalveolar lavage (BAL). Materials were collected from 79 patients with su...
Source: Polish Journal of Microbiology - October 10, 2023 Category: Microbiology Authors: Maria Teresa Szymankiewicz Anna Szczepanska Elzbieta Stefaniuk Source Type: research

Clinical Presentation and Co-Detection of Respiratory Pathogens in Children Under 5 Years with Non-COVID-19 Bacterial and Viral Respiratory Tract Infections: A Prospective Study in Bia łystok, Poland (2021-2022)
CONCLUSIONS Consistent with previous studies, we found a high prevalence of rhinoviruses, despite ongoing implementation of non-pharmaceutical interventions to contain the COVID-19 pandemic. Co-detection of 2 different respiratory pathogens was frequent, but we found no evidence that this was associated with the severity of infections.PMID:37794657 | DOI:10.12659/MSM.941785 (Source: Medical Science Monitor)
Source: Medical Science Monitor - October 5, 2023 Category: Research Authors: Katarzyna Zdanowicz Dawid Lewandowski Piotr Majewski Kinga P ółkośnik Nikolina Liwoch-Nienartowicz Joanna Resze ć-Giełażyn Dariusz Marek Lebensztejn Artur Sulik Kacper Toczy łowski Source Type: research

Bronchiectasis
Presse Med. 2023 Sep 29:104174. doi: 10.1016/j.lpm.2023.104174. Online ahead of print.ABSTRACTBronchiectasis is a final common pathway of a wide variety of underlying conditions including infectious, autoimmune, allergic, genetic and inflammatory conditions. Patients experience a chronic disease with variable clinical symptoms and course, but most experience cough, sputum production and recurrent exacerbations. Symptoms of bronchiectasis lead to poor quality of life and exacerbations are the major driver of morbidity and mortality. Patients are often chronically infected with bacteria with the most common being Pseudomonas...
Source: Presse Medicale - October 1, 2023 Category: General Medicine Authors: Miguel Barbosa James D Chalmers Source Type: research

Identification of cystic fibrosis transmembrane conductance regulator gene (CFTR) variants: A retrospective study on the western and southern regions of Saudi Arabia
CONCLUSION: This study highlighted features of patients with CF residing in the Western and Southern regions of Saudi Arabia. Six of the 26 CFTR variants were common in these patients. We also report, for the first time, a novel variant and other CFTR variants that are yet to be reported in Saudi Arabia. These findings could help establish a foundation for cystic fibrosis screening in Saudi Arabia and may assist in clinical diagnosis and prognosis.PMID:37777263 | DOI:10.15537/smj.2023.44.10.20230290 (Source: Saudi Medical Journal)
Source: Saudi Medical Journal - September 30, 2023 Category: Middle East Health Authors: Talal Almaghamsi Wejdan Ba Attiyah Mona Bahasan Badi A Alotaibi Shahad F AlAhmadi Mehenaz Hanbazazh Abeer Zakariyah Rimah A Saleem Munaifah K AlAnezi Yousef Hawsawi Source Type: research