Haemophilus Influenzae (Hib) Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Haemophilus influenzae endocarditis: a case report and literature review
ConclusionNative tricuspid valve IE is an uncommon entity, especially in the absence of IV drug use. Haemophilus influenzae is an extremely rare cause of IE, with a literature review showing merely 15 reported cases. This article cites the 16th case of HI-IE published in the literature. (Source: Infection)
Source: Infection - March 15, 2024 Category: Infectious Diseases Source Type: research

Early predictors of bacterial pneumonia infection in children with congenital heart disease after cardiopulmonary bypass: a single-centre retrospective study
Conclusions In our study, weight, PCT and CRP were found to be independent predictors of pulmonary bacterial infection after CPB. Moreover, PCT was the most specific predictor, and CRP was the most sensitive independent predictor that might be beneficial for the early diagnosis of pulmonary bacterial infection after CPB in patients with CHD. (Source: BMJ Open)
Source: BMJ Open - March 14, 2024 Category: General Medicine Authors: Wang, Q., Liu, H., Zou, L., Cun, Y., Shu, Y., Patel, N., Yu, D., Mo, X. Tags: Open access, Cardiovascular medicine Source Type: research

Advancing the National Immunization Program in an era of achieving universal vaccine coverage in China and beyond
CONCLUSION: The articles emphasize the need for government leadership, strategic policymaking, and public awareness to enhance vaccine coverage and equity. The VaxLab will continue strengthening China's NIP by focusing on vaccine financing, emphasizing diversity, equity, and inclusion, and improving maternal vaccination coverage. Research will extend to Southeast Asian and Western Pacific regions, especially in middle-income countries facing challenges in vaccine financing and delivery. The collective efforts outlined in this collection show a commitment to evolving and adapting immunization strategies to meet global healt...
Source: Cancer Control - March 13, 2024 Category: Cancer & Oncology Authors: Shu Chen Lance E Rodewald Anna Heng Du Shenglan Tang Source Type: research

Impact of normalized COVID-19 prevention and control measures on lower respiratory tract infection pathogenesis in hospitalized children
CONCLUSION: Public health interventions for COVID-19 prevention are beneficial to reduce the incidence of LRTIs in children by limiting the prevalence of ADV, MP, BP, and M. catarrhalis, but which have limited restrictive effects on other common LRTIs-associated pathogens. Collectively, the data in this study comprehensively investigated the effects of COVID-19 pandemic on the epidemiological characteristics of respiratory pathogens, which will be beneficial for improving early preventive measures.PMID:38476493 | PMC:PMC10927715 | DOI:10.3389/fpubh.2024.1367614 (Source: Adv Data)
Source: Adv Data - March 13, 2024 Category: Epidemiology Authors: Yuan Feng Huaixiao Zhang Bo Zhang Yinfei Zhou Haibin Yuan Source Type: research

In Vitro Reconstruction of Bacterial β-Barrel Membrane Protein Assembly Using E. coli Microsomal (Mid-Density) Membrane
Methods Mol Biol. 2024;2778:65-81. doi: 10.1007/978-1-0716-3734-0_5.ABSTRACTThe in vitro reconstruction assay enables us to evaluate in detail the insertion and proper protein folding (together termed assembly) of β-barrel membrane proteins. Here, we introduce an in vitro reconstitution experiments using isolated membrane fractions from Escherichia coli (E. coli). Membrane fractions isolated from E. coli cells and disrupted by sonication, which we have termed E. coli microsomal (mid-density) membrane (EMM), are ideal for biochemical experiments, as they can be harvested by high-speed centrifugation and do not require ultr...
Source: Molecular Medicine - March 13, 2024 Category: Molecular Biology Authors: Eriko Aoki Edward Germany Takuya Shiota Source Type: research

Bacterial antigens and asthma: a comparative study of common respiratory pathogenic bacteria
J Asthma. 2024 Mar 13:1-15. doi: 10.1080/02770903.2024.2330063. Online ahead of print.ABSTRACTIn a previous study we have shown that, in the presence of interleukin (IL)-33, repeated, per-nasal challenge of murine airways with Streptococcus pneumoniae (S. pneumoniae) organisms induces human asthma-like airways inflammation. It is not clear, however, whether this effect is unique or manifest in response to other common respiratory pathogens. To explore this, airways of BALB/c mice were repeatedly challenged per-nasally with formaldehyde-inactivated bacterial bodies in the presence or absence of murine recombinant IL-33. Ser...
Source: Journal of Asthma - March 13, 2024 Category: Respiratory Medicine Authors: Jie Pang Yifan Shi Dan Peng Lele Cui Yingjie Xu Wenjing Wang Yue Hu Yiran Yang Jingjing Wang Xiaofeng Qin Yue Zhang Hao Meng Dan Wang Ge Bai Huihui Yuan Jie Liu Zhe Lv Yan Li Ye Cui Wenjun Wang Kewu Huang Chris J Corrigan Wei Wang Yan Chen Sun Ying Source Type: research

Advancing the National Immunization Program in an era of achieving universal vaccine coverage in China and beyond
ConclusionThe articles emphasize the need for government leadership, strategic policymaking, and public awareness to enhance vaccine coverage and equity. The VaxLab will continue strengthening China ’s NIP by focusing on vaccine financing, emphasizing diversity, equity, and inclusion, and improving maternal vaccination coverage. Research will extend to Southeast Asian and Western Pacific regions, especially in middle-income countries facing challenges in vaccine financing and delivery. The co llective efforts outlined in this collection show a commitment to evolving and adapting immunization strategies to meet global hea...
Source: Infectious Diseases of Poverty - March 13, 2024 Category: Infectious Diseases Source Type: research

A Pediatric Investigators Collaborative Network on Infections in Children (PICNIC) multi-centre Canadian descriptive analysis of < em > Haemophilus influenzae < /em > bacteremia in children: Emerging serotypes
CONCLUSION: In the era of efficacious conjugate Hib vaccines, NTHi, Hia and Hif have emerged as the leading causes of invasive Hi in Canadian children, with Hia being most likely to result in meningitis and complicated disease. A vaccine for all NTHi and THi would be ideal, but knowledge of the current disease burden from circulating strains will inform prioritization of vaccine targets.PMID:38463901 | PMC:PMC10919449 | DOI:10.14745/ccdr.v49i09a02 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - March 11, 2024 Category: Infectious Diseases Authors: Craig Frankel Joan Robinson Sarah Khan Mohammad Alghounaim Jane McDonald Alison Lopez Sergio Fanella John Gunawan Jacqueline Wong Jeannette Comeau Jennifer Bowes Robert Slinger Angela Kalia Ashley Roberts Kirk Leifso Marina Ulanova Michelle Barton Source Type: research

Preparation and immunogenicity evaluation of C-HapS-P6 fusion protein vaccine against nontypeable Haemophilus influenzae in mice
In conclusion, our results demonstrated that the C-HapS-P6 fusion protein vaccine can significantly enhance humoral and cell immune responses and effectively prevent against NTHi infection in the respiratory tract in murine models.PMID:38461565 | DOI:10.1016/j.ijmm.2024.151616 (Source: International Journal of Medical Microbiology)
Source: International Journal of Medical Microbiology - March 10, 2024 Category: Microbiology Authors: Nan Hu Weifeng Li Zihong Zhao Yueli Chang Cai Wang Yutuo Zhang Source Type: research

Changes in Spectrum of Respiratory Pathogen Infections and Disease Severity Among Children in Hohhot, China: Impact of COVID-19 Prevention Measures
CONCLUSIONS SARS-CoV-2 peaked around November 2022, influenza A peaked in March 2023, and other pathogens like respiratory syncytial virus and influenza B virus were greatly reduced after December 2022. Inflammatory markers and respiratory symptoms decreased after December 2022, except for SARS-CoV-2.PMID:38451880 | DOI:10.12659/MSM.942845 (Source: Medical Science Monitor)
Source: Medical Science Monitor - March 7, 2024 Category: Research Authors: Yan-Zi Gan Peng Yang Rui Liu Yan-Hai Wang Yu-Wei Hu Yang Yang Source Type: research