Haemophilus Influenzae (Hib) Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Case of Haemophilus influenzae urethritis in a male patient
We report a case of H. influenzae urethritis and describe a relatively novel treatment approach. A man presented to Melbourne Sexual Health Centre with a 3-day history of penile discharge and dysuria. He engaged in condomless oral and anal sex with casual male partners in preceding months. On examination, purulent urethral discharge was noted. Urethral microscopy showed Gram-positive bacilli and epithelial cells. Screening for chlamydia, gonorrhoea, Mycoplasma genitalium, Trichomonas vaginalis, HIV and syphilis was performed. He was treated for NGU with a 1-week course of doxycycline. Initial investigations were all negati...
Source: Sexually Transmitted Infections - April 18, 2024 Category: Sexual Medicine Authors: Samra, R. S., Plummer, E. L., Vodstrcil, L., Bradshaw, C. S. Tags: PostScript Source Type: research

Human genetic associations of the airway microbiome in chronic obstructive pulmonary disease
Respir Res. 2024 Apr 16;25(1):165. doi: 10.1186/s12931-024-02805-2.ABSTRACTLittle is known about the relationships between human genetics and the airway microbiome. Deeply sequenced airway metagenomics, by simultaneously characterizing the microbiome and host genetics, provide a unique opportunity to assess the microbiome-host genetic associations. Here we performed a co-profiling of microbiome and host genetics with the identification of over 5 million single nucleotide polymorphisms (SNPs) through deep metagenomic sequencing in sputum of 99 chronic obstructive pulmonary disease (COPD) and 36 healthy individuals. Host gen...
Source: Respiratory Care - April 15, 2024 Category: Respiratory Medicine Authors: Jingyuan Gao Yuqiong Yang Xiaopeng Xiang Huimin Zheng Xinzhu Yi Fengyan Wang Zhenyu Liang Dandan Chen Weijuan Shi Lingwei Wang Di Wu Shengchuan Feng Qiaoyun Huang Xueping Li Wensheng Shu Rongchang Chen Nanshan Zhong Zhang Wang Source Type: research

An infant mouse model of influenza-driven nontypeable Haemophilus influenzae colonization and acute otitis media suitable for preclinical testing of novel therapies
Infection and Immunity, Ahead of Print. (Source: Infection and Immunity)
Source: Infection and Immunity - April 11, 2024 Category: Infectious Diseases Authors: Katherine R. LandwehrCaitlyn M. GranlandKelly M. MartinovichNaomi M. ScottElke J. SeppanenLuke BerryDeborah StricklandAlma FulurijaPeter C. RichmondLea-Ann S. Kirkham1Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Perth, A Source Type: research

Evaluating omadacycline dosing regimens against drug-resistant pathogens including Staphylococcus aureus , Streptococcus pneumoniae and Haemophilus influenzae in adults: a pharmacokinetic/pharmacodynamic analysis using Monte Carlo simulation
In conclusion, approved oral/intravenous loading and maintenance doses of omadacycline showed enough efficacy in the treatment of ABSSI and CABP caused by the main drug-resistant pathogens.PMID:38591989 | DOI:10.1080/1120009X.2024.2339706 (Source: Journal of Chemotherapy)
Source: Journal of Chemotherapy - April 9, 2024 Category: Cancer & Oncology Authors: Xiao-Chen Wei Ming-Feng Zhao Xia Xiao Source Type: research

Childhood vaccination coverage and regional differences in Swiss birth cohorts 2012-2021: Are we on track?
CONCLUSION: Full vaccination coverage in Swiss children is still below 90 % with many vaccinations administered delayed. Given regional differences, missed or delayed booster vaccinations, and differences in vaccine-specific acceptability, more effort may be needed to achieve national vaccination targets.PMID:38593195 | DOI:10.1016/j.vaccine.2023.10.043 (Source: Vaccine)
Source: Vaccine - April 9, 2024 Category: Allergy & Immunology Authors: Simeon J Z ürcher Andri Signorell Anja L échot-Huser Christoph Aebi Carola A Huber Source Type: research

Immunogenicity and safety of adsorbed diphtheria-purified pertussis-tetanus-inactivated polio (Sabin strain)-Haemophilus type b conjugate combined vaccine (DPT-IPV-Hib) in healthy Japanese Infants ≥ 2 and & lt; 43 months of Age: A phase III, multicenter, active controlled, assessor-blinded, randomized, parallel-group study
CONCLUSION: A single-agent Gobik, the first DPT-IPV-Hib pentavalent vaccine approved in Japan, was confirmed to simultaneously provide primary and booster immunizations against Hib infection, pertussis, diphtheria, tetanus, and poliomyelitis and to have a preventive effect and safety comparable to concomitant vaccination with Hib (ActHIB®) and DPT-IPV quadrivalent vaccine (Tetrabik).PMID:38582691 | DOI:10.1016/j.vaccine.2023.03.077 (Source: Vaccine)
Source: Vaccine - April 6, 2024 Category: Allergy & Immunology Authors: Takashi Nakano Masumi Hasegawa Mai Endo Keiko Matsuda Hoshio Tamai Source Type: research

Global vaccine coverage and childhood survival estimates: 1990-2019
CONCLUSION: Vaccines continue to reduce childhood mortality significantly, especially in Gavi-supported countries, emphasizing the need for increased investment in routine immunization programmes.PMID:38562199 | PMC:PMC10976869 | DOI:10.2471/BLT.23.290129 (Source: Bulletin of the World Health Organization)
Source: Bulletin of the World Health Organization - April 2, 2024 Category: International Medicine & Public Health Authors: Haijun Zhang Bryan Patenaude Haonan Zhang Mark Jit Hai Fang Source Type: research