Evaluation of the QIAstat-Dx Meningitis/Encephalitis Panel, a multiplex PCR platform for the detection of community-acquired meningoencephalitis
J Clin Microbiol. 2023 Sep 13:e0042623. doi: 10.1128/jcm.00426-23. Online ahead of print.ABSTRACTRapid identification of the causative pathogens of central nervous system infections is essential for providing appropriate management and improving patient outcomes. The performance of QIAstat-Dx Meningitis/Encephalitis (ME) Panel-a multiplex PCR testing platform-in detecting pathogens implicated in meningitis and/or encephalitis was evaluated using BioFire FilmArray ME Panel as a comparator method. This multicenter study analyzed 585 retrospective residual cerebrospinal fluid specimens and 367 contrived specimens. The QIAstat...
Source: Herpes - September 13, 2023 Category: Infectious Diseases Authors: Thomas Sundelin Johanna Bialas Juana de Diego Markus Hermanowski Hendrik Leibhan L éa Ponderand Marti Juanola-Falgarona Tara Jones Melisa Rey Sarah Johnson Josep Pareja Yvan Caspar Source Type: research

Clinical application of metagenomic next-generation sequencing in purulent meningitis: a case seri
CONCLUSIONS: mNGS is effective for the immediate detection of pathogens, which can in turn facilitate prompt diagnosis and treatment among individuals with purulent meningitis, especially if conventional CSF results (such as CSF culture and polymerase chain reaction) are negative.PMID:37661684 | DOI:10.24953/turkjped.2022.691 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - September 4, 2023 Category: Pediatrics Authors: Min Ding Chunfeng Yang Yumei Li Source Type: research

Clinical application of metagenomic next-generation sequencing in purulent meningitis: a case seri
CONCLUSIONS: mNGS is effective for the immediate detection of pathogens, which can in turn facilitate prompt diagnosis and treatment among individuals with purulent meningitis, especially if conventional CSF results (such as CSF culture and polymerase chain reaction) are negative.PMID:37661684 | DOI:10.24953/turkjped.2022.691 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - September 4, 2023 Category: Pediatrics Authors: Min Ding Chunfeng Yang Yumei Li Source Type: research

Clinical application of metagenomic next-generation sequencing in purulent meningitis: a case seri
CONCLUSIONS: mNGS is effective for the immediate detection of pathogens, which can in turn facilitate prompt diagnosis and treatment among individuals with purulent meningitis, especially if conventional CSF results (such as CSF culture and polymerase chain reaction) are negative.PMID:37661684 | DOI:10.24953/turkjped.2022.691 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - September 4, 2023 Category: Pediatrics Authors: Min Ding Chunfeng Yang Yumei Li Source Type: research

Clinical application of metagenomic next-generation sequencing in purulent meningitis: a case seri
CONCLUSIONS: mNGS is effective for the immediate detection of pathogens, which can in turn facilitate prompt diagnosis and treatment among individuals with purulent meningitis, especially if conventional CSF results (such as CSF culture and polymerase chain reaction) are negative.PMID:37661684 | DOI:10.24953/turkjped.2022.691 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - September 4, 2023 Category: Pediatrics Authors: Min Ding Chunfeng Yang Yumei Li Source Type: research

Clinical application of metagenomic next-generation sequencing in purulent meningitis: a case seri
CONCLUSIONS: mNGS is effective for the immediate detection of pathogens, which can in turn facilitate prompt diagnosis and treatment among individuals with purulent meningitis, especially if conventional CSF results (such as CSF culture and polymerase chain reaction) are negative.PMID:37661684 | DOI:10.24953/turkjped.2022.691 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - September 4, 2023 Category: Pediatrics Authors: Min Ding Chunfeng Yang Yumei Li Source Type: research

Clinical application of metagenomic next-generation sequencing in purulent meningitis: a case seri
CONCLUSIONS: mNGS is effective for the immediate detection of pathogens, which can in turn facilitate prompt diagnosis and treatment among individuals with purulent meningitis, especially if conventional CSF results (such as CSF culture and polymerase chain reaction) are negative.PMID:37661684 | DOI:10.24953/turkjped.2022.691 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - September 4, 2023 Category: Pediatrics Authors: Min Ding Chunfeng Yang Yumei Li Source Type: research

Clinical application of metagenomic next-generation sequencing in purulent meningitis: a case seri
CONCLUSIONS: mNGS is effective for the immediate detection of pathogens, which can in turn facilitate prompt diagnosis and treatment among individuals with purulent meningitis, especially if conventional CSF results (such as CSF culture and polymerase chain reaction) are negative.PMID:37661684 | DOI:10.24953/turkjped.2022.691 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - September 4, 2023 Category: Pediatrics Authors: Min Ding Chunfeng Yang Yumei Li Source Type: research

Clinical application of metagenomic next-generation sequencing in purulent meningitis: a case seri
CONCLUSIONS: mNGS is effective for the immediate detection of pathogens, which can in turn facilitate prompt diagnosis and treatment among individuals with purulent meningitis, especially if conventional CSF results (such as CSF culture and polymerase chain reaction) are negative.PMID:37661684 | DOI:10.24953/turkjped.2022.691 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - September 4, 2023 Category: Pediatrics Authors: Min Ding Chunfeng Yang Yumei Li Source Type: research

Clinical application of metagenomic next-generation sequencing in purulent meningitis: a case seri
CONCLUSIONS: mNGS is effective for the immediate detection of pathogens, which can in turn facilitate prompt diagnosis and treatment among individuals with purulent meningitis, especially if conventional CSF results (such as CSF culture and polymerase chain reaction) are negative.PMID:37661684 | DOI:10.24953/turkjped.2022.691 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - September 4, 2023 Category: Pediatrics Authors: Min Ding Chunfeng Yang Yumei Li Source Type: research

Clinical application of metagenomic next-generation sequencing in purulent meningitis: a case seri
CONCLUSIONS: mNGS is effective for the immediate detection of pathogens, which can in turn facilitate prompt diagnosis and treatment among individuals with purulent meningitis, especially if conventional CSF results (such as CSF culture and polymerase chain reaction) are negative.PMID:37661684 | DOI:10.24953/turkjped.2022.691 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - September 4, 2023 Category: Pediatrics Authors: Min Ding Chunfeng Yang Yumei Li Source Type: research

Clinical application of metagenomic next-generation sequencing in purulent meningitis: a case seri
CONCLUSIONS: mNGS is effective for the immediate detection of pathogens, which can in turn facilitate prompt diagnosis and treatment among individuals with purulent meningitis, especially if conventional CSF results (such as CSF culture and polymerase chain reaction) are negative.PMID:37661684 | DOI:10.24953/turkjped.2022.691 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - September 4, 2023 Category: Pediatrics Authors: Min Ding Chunfeng Yang Yumei Li Source Type: research

Clinical application of metagenomic next-generation sequencing in purulent meningitis: a case seri
CONCLUSIONS: mNGS is effective for the immediate detection of pathogens, which can in turn facilitate prompt diagnosis and treatment among individuals with purulent meningitis, especially if conventional CSF results (such as CSF culture and polymerase chain reaction) are negative.PMID:37661684 | DOI:10.24953/turkjped.2022.691 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - September 4, 2023 Category: Pediatrics Authors: Min Ding Chunfeng Yang Yumei Li Source Type: research

Clinical application of metagenomic next-generation sequencing in purulent meningitis: a case seri
CONCLUSIONS: mNGS is effective for the immediate detection of pathogens, which can in turn facilitate prompt diagnosis and treatment among individuals with purulent meningitis, especially if conventional CSF results (such as CSF culture and polymerase chain reaction) are negative.PMID:37661684 | DOI:10.24953/turkjped.2022.691 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - September 4, 2023 Category: Pediatrics Authors: Min Ding Chunfeng Yang Yumei Li Source Type: research

Clinical application of metagenomic next-generation sequencing in purulent meningitis: a case seri
CONCLUSIONS: mNGS is effective for the immediate detection of pathogens, which can in turn facilitate prompt diagnosis and treatment among individuals with purulent meningitis, especially if conventional CSF results (such as CSF culture and polymerase chain reaction) are negative.PMID:37661684 | DOI:10.24953/turkjped.2022.691 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - September 4, 2023 Category: Pediatrics Authors: Min Ding Chunfeng Yang Yumei Li Source Type: research