Effects of the storage of breast milk at different temperatures on total antioxidant capacity, total oxidant status, and paraoxonase-1 level.
This study aims to evaluate total antioxidant capacity (TAC), total oxidant status (TOS), and paraoxonase-1 (PON-1) levels of fresh and freezestored breast milk. Ten cc of breast milk was obtained from the mothers as the days between 10 and 15 in the morning within a 1-hour period. TAC, TOS, and PON-1 levels were evaluated in the fresh breast milk. Collected breast milk samples were divided into two groups for storage at -20°C or -80°C. Stored samples were tested for TAC, TOS, and PON-1 levels after 72 hours. The highest TAC level was detected in fresh breast milk (p
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Konak M, Minici M, Tarakçı N, Altunhan H, Toker A, Örs R Tags: Turk J Pediatr Source Type: research

Clearance of jaundice after the modified Kasai`s operation predicts survival outcomes in patients with biliary atresia.
Abstract Tamgal J, Damrongmanee A, Khorana J, Tepmalai K, Ukarapol N. Clearance of jaundice after the modified Kasai`s operation predicts survival outcomes in patients with biliary atresia. Turk J Pediatr 2019; 61: 7-12. The aim of this study was to assess the probability of survival with native liver (SNL) and the rate of esophageal variceal bleeding (EVB) as well as their potential risk factors, in patients diagnosed with Biliary Atresia (BA), who underwent the hepaticoportoenterostomy (HPE) by retrospectively reviewing medical records between 2007 and 2016. The subjects were classified as poor outcomes if they ...
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Tamgal J, Damrongmanee A, Khorana J, Tepmalai K, Ukarapol N Tags: Turk J Pediatr Source Type: research

Retinopathy of prematurity risk factors: Does human milk prevent retinopathy of prematurity?
Dündar S, Türkmen M Abstract Akyüz-Ünsal Aİ, Key Ö, Güler D, Bekmez S, Sagus M, Akcan AB, Kurt-Omurlu İ, Anık A, Oruç-Dündar S, Türkmen M. Retinopathy of prematurity risk factors: Does human milk prevent retinopathy of prematurity? Turk J Pediatr 2019; 61: 13-19. The aim of this study was to investigate the risk factors for Retinopathy of Prematurity (ROP) development and the potential effect of human breast milk among these factors. For this purpose, infants admitted to a tertiary referral clinic for ROP screening and treatment between April 2013 and May 2015, wer...
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Akyüz-Ünsal Aİ, Key Ö, Güler D, Bekmez S, Sagus M, Akcan AB, Kurt-Omurlu İ, Anık A, Oruç-Dündar S, Türkmen M Tags: Turk J Pediatr Source Type: research

Nasal nitric oxide levels in primary ciliary dyskinesia, cystic fibrosis and healthy children.
In this study, we aim to evaluate NIOX-MINOÒ, which is an easily applicable method for measuring nNO, in the diagnosis of patients with PCD and define diagnostic cut-off levels. Furthermore, determining the normal limits of nNO in healthy children and investigating nNO levels of children with cystic fibrosis (CF) are the other aims of this study. The children included in this study were 5 to 18.5 years old, 46 of them had PCD, 44 had CF and 200 were healthy children. To our knowledge, this work contains the widest population compared to previous studies. Subjects receiving steroids or antibiotics or those with any a...
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Güney E, Emiralioğlu N, Cinel G, Yalçın E, Doğru D, Kiper N, Özçelik HU Tags: Turk J Pediatr Source Type: research

The effectiveness of serum amyloid A for prediction of neonatal cholestasis associated with parenteral nutrition in premature infants.
The objective of this study was to evaluate the role of serial measurements of serum amyloid A (SAA) during PN and compare its` effectiveness with C-reactive protein (CRP) and procalcitonin (PCT). We also aimed to determine the risk factors for PN associated cholestasis (PNAC). Premature infants (
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Özkan H, Köksal N, Doğan P, Güney-Varal İ, Bağcı O, Özgür T Tags: Turk J Pediatr Source Type: research

Is serum procalcitonin level a reliable indicator in early diagnosis of congenital pneumonia?
k M Abstract Bozkaya D, Yiğit Ş, Yurdakök M. Is serum procalcitonin level a reliable indicator in early diagnosis of congenital pneumonia? Turk J Pediatr 2019; 61: 34-39. The clinical signs in congenital pneumonia mimic other conditions like transient tachypnea of the newborn (TTN) and respiratory distress syndrome (RDS). Differential diagnosis is difficult since laboratory findings have limited value. Procalcitonin (PCT) is an important and widely studied marker of infection. The aim of this study was to determine the diagnostic value of PCT in newborn patients hospitalized in the neonatal intensive care u...
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Bozkaya D, Yiğit Ş, Yurdakök M Tags: Turk J Pediatr Source Type: research

The pathogens and curative effects analysis of perianal abscess of infants under 3 months.
In conclusion, Klebsiella pneumoniae was the most common pathogen in perianal abscess of infants under 3 months and was commonly resistant to ampicillin and nitrofurantion. Since perianal abscess of infants under 3 months is a self-limited disorder, simple surgical intervention and synchronous sensitive antibiotic administration are suggested as the optimal management. PMID: 31559720 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Zhu Y, Xu F Tags: Turk J Pediatr Source Type: research

Bilateral Wilms tumors: Treatment results from a single center.
In this study, the outcome of BWT patients from a single center who were treated by the Turkish Pediatric Oncology Group (TPOG) Wilms Tumor Regimen were retrospectively reviewed. From 1990 to 2016, 30 patients with synchronous BWT were treated with a preoperative chemotherapy of vincristine and actinomycin-D (VA). Chemotherapy was continued until safe nephron sparing surgery (NSS) could be performed for as long as radiological tumor response continued; otherwise, the chemotherapy was intensified by adding doxorubicin (D) alternating with VA every 6 weeks. The median followup of patients was 59 months (4-297 months). The me...
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Aydın B, Akyüz C, Yalçın B, Ekinci S, Oğuz B, Akçören Z, Yıldız F, Varan A, Kurucu N, Büyükpamukçu M, Kutluk T Tags: Turk J Pediatr Source Type: research

Body mass index is decreased in children and adolescents with postural tachycardia syndrome.
Abstract Lin J, Zhao H, Ma L, Jiao F. Body mass index is decreased in children and adolescents with postural tachycardia syndrome. Turk J Pediatr 2019; 61: 52-58. Our intent was to explore the predictive value of body mass index (BMI) in differentiating between vasovagal syncope (VVS) and postural tachycardia syndrome (POTS) in children and adolescents. A total of 111 children and adolescents with POTS and 154 children and adolescents with VVS were included in our study. The control group included 82 healthy children and adolescents. Height and weight were measured in all participants. The headup tilt test was per...
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Lin J, Zhao H, Ma L, Jiao F Tags: Turk J Pediatr Source Type: research

Pulmonary complications following hematopoietic stem cell transplantation in children.
In conclusion; identifying children who are at risk for severe pulmonary complications and close longitudinal follow-up after HSCT by pediatric pulmonologists is mandatory to increase survival and life quality of these patients. PMID: 31559723 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Çıkı K, Doğru D, Kuşkonmaz B, Emiralioğlu N, Yalçın E, Özçelik U, Uçkan-Çetinkaya D, Kiper N Tags: Turk J Pediatr Source Type: research

Is there any relation between connective tissue growth factor and scar tissue in vesicoureteral reflux?
Ş Abstract Gültekin ND, Benzer M, Tekin-Neijmann Ş. Is there any relation between connective tissue growth factor and scar tissue in vesicoureteral reflux. Turk J Pediatr 2019; 61: 71-78. Vesicoureteral reflux (VUR) is the most common uropathy in childhood which leads to increased frequency of urinary tract infection (UTI) and renal scarring. Connective tissue growth factor (CTGF) plays an important role in the development of glomerular and tubulointerstitial fibrosis in progressive kidney diseases. The aim of this study was to investigate the relation between urinary CTGF and renal damage resulted from VU...
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Gültekin ND, Benzer M, Tekin-Neijmann Ş Tags: Turk J Pediatr Source Type: research

Does stable sitting influence upper limb function in children with cerebral palsy?
l M Abstract Seyhan K, Kerem-Günel M. Does stable sitting influence upper limb function in children with cerebral palsy? Turk J Pediatr 2019; 61: 79-84. Bilateral spastic cerebral palsy (BSCP) patients frequently need to use various sitting devices for body control and function. The aim of this study was to investigate whether the use of a belt to position the pelvis in an adjustable chair would affect upper limb function in preschool children with BSCP. Fortyone children with BSCP [mean age 44 ±11, range 18-60 months] classified according to the Gross Motor Function Classification System (GMFCS), as l...
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Seyhan K, Kerem-Günel M Tags: Turk J Pediatr Source Type: research

Prolonged QT dispersion is associated with pediatric syncope.
l S Abstract Bilici M, Fidancı-Dedeoğlu Z, Demir F, Akın A, Türe M, Balık H, Tan İ, Ertuğrul S. Prolonged QT dispersion is associated with pediatric syncope. Turk J Pediatr 2019; 61: 85-91. We aimed to find out whether QT dispersion can be used as a diagnostic marker in terms of syncope type, and recurrence risk. Fifty-two patients (28 male, 53.8%) admitted to the pediatric cardiology clinic with syncope were compared with 50 healthy controls (28 male, 56%; mean age: 13.8±2.3 years, range: 11-17 years) for QT dispersion (QTd) and other electrocardiographic findings. Gender, age, echocardiography,...
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Bilici M, Fidancı-Dedeoğlu Z, Demir F, Akın A, Türe M, Balık H, Tan İ, Ertuğrul S Tags: Turk J Pediatr Source Type: research

A novel mutation in two cousins with guanidinoacetate methyltransferase (GAMT) deficiency presented with autism.
FM Abstract Aydın Hİ, Sönmez FM. A novel mutation in two cousins with guanidinoacetate methyltransferase (GAMT) deficiency presented with autism. Turk J Pediatr 2019; 61: 92-96. Guanidinoacetate methyltransferase (GAMT) deficiency is a rare autosomal recessive disorder of creatine biosynthesis. Here, we report 9 and 10-year-old cousins with GAMT deficiency caused by a novel mutation who both exhibited neurodevelopmental retardation, seizures, behavioral problems, and autism that began during early infancy. The patients were diagnosed as having only autism and followed for years without a specific diagnosis...
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Aydın Hİ, Sönmez FM Tags: Turk J Pediatr Source Type: research

Acute lymphoblastic leukemia presenting as nephromegaly in a child: A rare case report.
Abstract Arora SK, Swarnim S, Hemal A, Bidhuri N. Acute lymphoblastic leukemia presenting as nephromegaly in a child: A rare case report. Turk J Pediatr 2019; 61: 97-101. Acute leukemia is the commonest pediatric malignancy with acute lymphoblastic leukemia (ALL) constituting about 75% of all leukemias. ALL commonly presents as fever, bleeding, bone pains, anemia, lymphadenopathy and hepatosplenomegaly. The liver, spleen or lymph nodes are the most common sites of extramedullary involvement in ALL, with renal involvement being relatively uncommon. The usual differential diagnosis of acquired massive bilateral neph...
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Arora SK, Swarnim S, Hemal A, Bidhuri N Tags: Turk J Pediatr Source Type: research

Severe iron deficiency anemia and anasarca edema due to excessive cow`s milk intake.
Abstract Mantadakis E, Zikidou P, Tsouvala E, Thomaidis S, Chatzimichael A. Severe iron deficiency anemia and anasarca edema due to excessive cow`s milk intake. Turk J Pediatr 2019; 61: 102-106. The authors describe a 13-month-old girl who presented with progressively worsening anasarca edema that developed over the last three weeks along with increasing fatigue. Over the last several months she was consuming progressively increasing amounts of fresh cow`s milk. Laboratory examinations on admission showed severe microcytic and hypochromic anemia (hemoglobin 3.8 g/dl) and hypoferritenemia indicative of iron deficie...
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Mantadakis E, Zikidou P, Tsouvala E, Thomaidis S, Chatzimichael A Tags: Turk J Pediatr Source Type: research

Treatment of maple syrup urine disease with high flow hemodialysis in a neonate.
T, Cam H Abstract Aygün F, Kıykım E, Aktuğlu-Zeybek Ç, Zubarioğlu T, Cam H. Treatment of maple syrup urine disease with high flow hemodialysis in a neonate. Turk J Pediatr 2019; 61: 107-110. Continious renal replacement therapy (CRRT) is a well recognizied treatment of choice in acute renal failure, however CRRT became a preferred treatment of metabolic emergencies with high leucine and ammonia levels like Maple syrup urine disease (MSUD). MSUD is a rare metabolic disorder caused by deficiency in the activity of the branched-chain a-ketoacid dehydrogenase complex. The toxic accumulation of branche...
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Aygün F, Kıykım E, Aktuğlu-Zeybek Ç, Zubarioğlu T, Cam H Tags: Turk J Pediatr Source Type: research

BK virus associated nephropathy and severe pneumonia in a kidney transplanted adolescent with Schimke immuneosseous- dysplasia.
We present an 18 year-old adolescent with juvenile onset SIOD who was diagnosed after renal transplantation and developed BK virus associated nephropathy (BKVAN) and severe pneumonia during follow-up. The patient developed nephrotic syndrome, unresponsive to immunosuppressives, at the age of 8 years. He had a history of meningitis, short stature, microcephaly, prominent ears, and bilateral cryptorchidism. A renal transplantation was performed at the age of 15 years. During follow-up, he suffered from leucopenia, urinary tract infections, herpes labialis, and candida esophagitis. Sanger sequencing of SMARCAL1 revealed a mis...
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Düzova A, Gülhan B, Topaloğlu R, Özaltın F, Cengiz AB, Yetimakman AF, Doğru D, Güçer Ş, Beşbaş N Tags: Turk J Pediatr Source Type: research

Asymptomatic giant congenital left atrial aneurysm.
Abstract Yakut K, Varan B, Erdoğan İ. Asymptomatic giant congenital left atrial aneurysm. Turk J Pediatr 2019; 61: 117-119. Congenital aneurysm of the left atrial appendage can be caused by congenital dysplasia of the pectinate muscles and may be accompanied by a congenital absence of the pericardium. Symptoms generally manifest after two decades and the most common symptom is atrial arrhythmia in the form of atrial fibrillation / flutter. A four year-old patient with no symptoms underwent an echocardiographic examination for the investigation of a heart murmur. Echocardiographic examination revealed a large cys...
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Yakut K, Varan B, Erdoğan İ Tags: Turk J Pediatr Source Type: research

Multimodality imaging findings of visceral myopathy in a child presenting with palpable abdominal mass.
We report a rare case of visceral myopathy in a child presenting with intraabdominal mass. We aimed to describe ultrasound, computed tomography and magnetic resonance enterography findings of this rare disease that has not been demonstrated before. Differential diagnosis of mural thickening with distinguishable layers in addition to intestinal dilatation in the absence of mesenteric inflammation includes visceral myopathy. PMID: 31559733 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Bayramoğlu Z, Yılmaz R, Demir AA, Ataizi-Çelikel Ç, Kombak FE, İkinci A, Yekeler E Tags: Turk J Pediatr Source Type: research

Intrathecal baclofen use in the management of tetanus related spasm: A case report.
tak A Abstract Şık G, Aydoseli A, Çıtak A. Intrathecal baclofen use in the management of tetanus related spasm: A case report. Turk J Pediatr 2019; 61: 126-129. Tetanus is an infectious disease of the central nervous system with high mortality rates characterized with respiratory distress and tonic muscle spasms. The most common cause of mortality is cardiovascular complications (40%) and respiratory distress (15%). Despite vaccination programs, tetanus remains to be a significant healthcare issue in developing nations. Prolonged sedation and administration of muscle relaxants prolongs the period on mech...
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Şık G, Aydoseli A, Çıtak A Tags: Turk J Pediatr Source Type: research

Recessive mutation in GALNT3 causes hyperphosphatemic familial tumoral calcinosis associated with chronic recurrent multifocal osteomyelitis.
We describe here an 11-year-old child who was diagnosed with these two conditions and was found to carry a splice site mutation c.1524+1G> A in the GALNT3 gene. PMID: 31559735 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Albaramki J, Dmour H, Shboul M, Bonnard C, Venkatesh B, Odeh R Tags: Turk J Pediatr Source Type: research

A rare clinical association: Barth syndrome and cystic fibrosis.
ır M Abstract Sağ E, Kamaşak T, Kaya G, Çakır M. A rare clinical association: Barth syndrome and cystic fibrosis. Turk J Pediatr 2019; 61: 134-138. Barth syndrome (BS) is a rare X-linked recessive metabolic disorder characterized by cardiomyopathy, hypotonia, neutropenia, growth retardation and 3-methylglutaconic aciduria type II. Cystic fibrosis is a common autosomal recessive genetic disorder in Caucasians. Herein, we reported a rare clinical association in an infant diagnosed based on clinical and genetic analysis. A six-month old boy admitted with chronic steatorrhea. The diagnosis of cystic fibrosi...
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Sağ E, Kamaşak T, Kaya G, Çakır M Tags: Turk J Pediatr Source Type: research

More than Ophelia syndrome: Multiple paraneoplastic syndromes in pediatric Hodgkin lymphoma.
In this report, we present an 11-year-old girl who had all these three paraneoplastic components synchronously before HL was identified. PMID: 31559737 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Demirsoy U, Alparslan B, Şen MC, Anık Y, Akansel G, Görür G, Gürel B, Aksu G, Çorapcıoğlu F Tags: Turk J Pediatr Source Type: research

Successful radiofrequency ablation of accessory pathway associated with left atrial appendage aneurysm in a low birthweight premature patient.
We present a premature case with a 2.4-kg birth weight, with non-immune hydrops due to supraventricular tachycardia. Despite the combination of amiodarone, esmolol and flecainide, tachyarrhythmia could not be controlled and radiofrequency ablation was applied due to left ventricular dysfunction. After the procedure the rhythm returned to normal sinus and left ventricular functions improved rapidly. The follow-up of the case continues without any problems. In this presentation, successful ablation of the accessory pathway associated with structural heart disease have been covered in the youngest and smallest patient to date...
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Ergül Y, Öztürk E, Özgür S Tags: Turk J Pediatr Source Type: research

Effect of iron supplementation during infancy period.
n SS PMID: 31559739 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - September 29, 2019 Category: Pediatrics Authors: Yalçın SS Tags: Turk J Pediatr Source Type: research

GPR56 homozygous nonsense mutation p.R271* associated with phenotypic variability in bilateral frontoparietal polymicrogyria.
üksel B, Hız-Kurul S, Cingöz S Abstract Öncü-Öner T, Ünalp A, Porsuk-Doru İ, Ağılkaya S, Güleryüz H, Saraç A, Ergüner B, Yüksel B, Hız-Kurul S, Cingöz S. GPR56 homozygous nonsense mutation p.R271* associated with phenotypic variability in bilateral frontoparietal polymicrogyria. Turk J Pediatr 2018; 60: 229-237. Polymicrogyria is a disorder of neuronal migration characterized by excessive cortical folding and partially fused gyri separated by shallow sulci. Homozygous mutations in the GPR56 gene, which regulates migration of neural precursor cells,...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Öncü-Öner T, Ünalp A, Porsuk-Doru İ, Ağılkaya S, Güleryüz H, Saraç A, Ergüner B, Yüksel B, Hız-Kurul S, Cingöz S Tags: Turk J Pediatr Source Type: research

Efficacy of rufinamide in childhood refractory epilepsy.
The objective of this study was to evaluate the reliability of rufinamide and its impact on seizure frequency in patients diagnosed with drug-resistant epilepsy, where seizures could not be controlled with `classical` antiepileptic drugs. We retrospectively reviewed the data of epileptic patients who were followed up between January 2004 and December 2014 in the Pediatric Neurology Department. Patients who were diagnosed with `drug resistant epilepsy` and treated with rufinamide were evaluated. Decrease in seizure frequency and drug side effects were assessed as parameters. A total of 38 patients (14 girls, 24 boys) with a...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Yıldız EP, Hızlı Z, Bektaş G, Ulak-Özkan M, Tatlı B, Aydınlı N, Çalışkan M, Özmen M Tags: Turk J Pediatr Source Type: research

Glycemic control and health behaviors in adolescents with type 1 diabetes.
can O, Bundak R Abstract Yetim A, Alikaşifoğlu M, Baş F, Eliaçık K, Çığ G, Erginöz E, Ercan O, Bundak R. Glycemic control and health behaviors in adolescents with type 1 diabetes. Turk J Pediatr 2018; 60: 244-254. The purpose of this study was to determine the health/health risk behaviors of a group of Turkish adolescents with type 1 diabetes (T1D) to determine the prevalence and explore the exact effect of these behaviors on glycemic control (GC). A total of 210 adolescents (age 12-20 years; diabetes duration> 6 months; no additional comorbidities), completed a self-administered questi...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Yetim A, Alikaşifoğlu M, Baş F, Eliaçık K, Çığ G, Erginöz E, Ercan O, Bundak R Tags: Turk J Pediatr Source Type: research

The influence of media on the sleep quality in adolescents.
This study was conducted to evaluate the influence of media devices on sleep quality in adolescents. Applying a descriptive design, the study was carried out with 9th, 10th and 11th grade students (N=392, 52.0% female, average age 16.04±0.86) who were attending Konya High School between the dates of January 18 and 22, 2016. Changes were seen to occur in the wake-up times of those who had either a television or a computer in their bedrooms (p
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Akçay D, Akçay BD Tags: Turk J Pediatr Source Type: research

Hereditary spherocytosis: Retrospective evaluation of 65 children.
k N, Kara A Abstract Güngör A, Yaralı N, Fettah A, Ok-Bozkaya İ, Özbek N, Kara A. Hereditary spherocytosis: Retrospective evaluation of 65 children. Turk J Pediatr 2018; 60: 264-269. Hereditary spherocytosis (HS) is a common cause of congenital hemolytic anemia in Caucasians and it could be diagnosed at any age. The aim of this study is to examine the demographic characteristics, clinical features and laboratory findings of children with HS and their complications observed during follow up. Sixty-five patients, with hereditary spherocytosis between January 2008 and September 2013, were enrolled in...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Güngör A, Yaralı N, Fettah A, Ok-Bozkaya İ, Özbek N, Kara A Tags: Turk J Pediatr Source Type: research

Advantage of the subcutaneous immunoglobulin replacement therapy in primary immunodeficient patients with or without secondary protein loss.
l;zkan F, Erol M, Tezcan İ Abstract Gür-Çetinkaya P, Çağdaş-Ayvaz DN, Öksüz AB, Ertoy A, Hayran U, Özkan F, Erol M, Tezcan İ. Advantage of the subcutaneous immunoglobulin replacement therapy in primary immunodeficient patients with or without secondary protein loss. Turk J Pediatr 2018; 60: 270-276. In recent years subcutaneous immunoglobulin is widely used for primary immunodeficient patients. Subcutaneous administration provides a more stable and higher serum immunoglobulin levels due to continuous and steady transition from lymphatics to the systemic circulation. We aimed t...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Gür-Çetinkaya P, Çağdaş-Ayvaz DN, Öksüz AB, Ertoy A, Hayran U, Özkan F, Erol M, Tezcan İ Tags: Turk J Pediatr Source Type: research

High alert medications administration errors in neonatal intensive care unit: A pediatric tertiary hospital experience.
Abstract Labib JR, Youssef MRL, Abd El Fatah SAM. High alert medications administration errors in neonatal intensive care unit: A pediatric tertiary hospital experience. Turk J Pediatr 2018; 60: 277-285. Labib JR, Youssef MRL, Abd El Fatah SAM. High alert medications administration errors in neonatal intensive care unit: A pediatric tertiary hospital experience. Turk J Pediatr 2018; 60: 277-285. This is a hospital-based descriptive cross sectional study, implemented in the NICU, at Cairo University Pediatric hospital. A convenient sample of 33 bedside NICU nurses, who agreed to participate was recruited. A valid, ...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Labib JR, Labib-Youssef MR, Fatah S Tags: Turk J Pediatr Source Type: research

Gelsolin levels in patients with bronchiolitis.
In this study, the aim was to determine the clinical predictiveness of plasma gelsolin levels (pGSN) in acute bronchiolitis. From December 2013 to May 2014, 52 patients with bronchiolitis (aged 0.05). Recent studies reported that pGSN levels can be used as a biomarker in sepsis, inflammation and injuries. In this study, we have demonstrated that pGSN level is not a predictive biomarker of bronchiolitis and its severity. Hence, we hypothesized that pGSN levels can be used in bacterial infections rather than viral infections as a biomarker. PMID: 30511541 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Hüsrevoğlu-Esen F, Altuner-Torun Y, Karakükçü Ç, Köse S, Şehriyaroğlu A, Kafadar D, Esen A, Köse M Tags: Turk J Pediatr Source Type: research

Attitudes of physicians concerning vaccines not included in the national immunization schedule.
AE, Beyazova U Abstract Çataklı T, Duyan-Çamurdan A, Aksakal-Baran FN, Güven AE, Beyazova U. Attitudes of physicians concerning vaccines not included in the national immunization schedule. Turk J Pediatr 2018; 60: 290-297. The aim of this study was to identify attitudes of family physicians and pediatricians working in sub-provinces of central Ankara concerning rotavirus (RV), human papilloma virus (HPV), meningococcal conjugate vaccine (MenACWY-MCV4) and adolescent and adult pertussis (Tdap) vaccines which are not included in the National Immunization Schedule (NIS). Questionnaires were condu...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Çataklı T, Duyan-Çamurdan A, Aksakal-Baran FN, Güven AE, Beyazova U Tags: Turk J Pediatr Source Type: research

Birth outcomes after inadvertent use of category X drugs contraindicated in pregnancy: Where is the real risk?
nar T, Vural K Abstract Öztürk Z, Ölmez E, Gürpınar T, Vural K. Birth outcomes after inadvertent use of category X drugs contraindicated in pregnancy: Where is the real risk? Turk J Pediatr 2018; 60: 298-305. Drugs contraindicated in pregnancy are medicines that should be avoided by pregnant women, since they carry a concern for teratogenicity or there is no indication for their use during pregnancy. It does not mean that exposures to these drugs always cause harm. The aim of the present study was to investigate the risk of adverse outcomes following maternal exposure to the drugs contraindic...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Öztürk Z, Ölmez E, Gürpınar T, Vural K Tags: Turk J Pediatr Source Type: research

Neonatal atrial flutter: Three cases and review of the literature.
il;etinkaya M Abstract Yılmaz-Semerci S, Bornaun H, Kurnaz D, Cebeci B, Babayiğit A, Büyükkale G, Çetinkaya M. Neonatal atrial flutter: Three cases and review of the literature. Turk J Pediatr 2018; 60: 306-309. Atrial flutter (AFl) is known to be a seldom type of fetal and neonatal arrhythmia. Although it could end in severe morbidities such as hydrops fetalis or even death, with early prenatal diagnosis and prompt therapeutic approaches the majority of AFl cases show good prognosis. Neonatal AFl might be resistant to first step therapies. Therefore, secondary agents like flecainide, amiodarone...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Yılmaz-Semerci S, Bornaun H, Kurnaz D, Cebeci B, Babayigit A, Büyükkale G, Çetinkaya M Tags: Turk J Pediatr Source Type: research

A case of steroid-resistance Hashimoto's encephalopathy presenting with sensorimotor polyneuropathy.
We report a case of steroid-resistance HE with sensorimotor polyneuropathy, as a rare presentation of this disorder. Our case showed that HE may present with sensorimotor polyneuropathy; therefore HE should be considered in the differential diagnoses of polyneuropathy. PMID: 30511545 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Emeksiz S, Kutlu NO, Alaçakır N, Çaksen H Tags: Turk J Pediatr Source Type: research

A novel mutation of the MYH7 gene in a patient with hypertrophic cardiomyopathy.
Abstract Goel N, Huddleston CB, Fiore AC. A novel mutation of the MYH7 gene in a patient with hypertrophic cardiomyopathy. Turk J Pediatr 2018; 60: 315-318. Hypertrophic cardiomyopathy (HCM) is a genetic disorder characterized by asymmetric cardiac hypertrophy due to inherited mutations in genes that encode sarcomeric proteins. MYH7, which encodes β-myosin heavy chain, is among the most commonly mutated genes in patients affected by HCM. We aimed to identify the specific mutation responsible for HCM in a six-month old Caucasian patient. NextGen DNA sequencing revealed a novel p.Ala1328Thr (A1328T) mutation of...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Goel N, Huddleston CB, Fiore AC Tags: Turk J Pediatr Source Type: research

A case of atypically located leiomyoma mimicking axillary lymphadenomegaly.
Abstract Cevizci MN, Fettah A, Kabalar ME. A case of atypically located leiomyoma mimicking axillary lymphadenomegaly. Turk J Pediatr 2018; 60: 319-321. Leiomyomas are benign smooth muscle tumors rarely seen in children and may occur anywhere in the body containing smooth muscle. Here, we report a case of a 4-year-old girl presenting with swelling in the left axillary region and with pain during arm movements. The solid mass in the axillary region was totally excised. The patient was discharged without complications on the same day. PMID: 30511547 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Cevizci MN, Fettah A, Kabalar ME Tags: Turk J Pediatr Source Type: research

A case of myeloid sarcoma presenting with an orbital mass, hearing loss, and multiple cranial neuropathies.
Abstract Lim SH, Nam HN, Lim KI, Jeon IS. A case of myeloid sarcoma presenting with an orbital mass, hearing loss, and multiple cranial neuropathies. Turk J Pediatr 2018; 60: 322-325. Primary myeloid sarcoma occurring in multiple sites; orbit, ear, brain, and spinal cord is a rare clinical entity. A 15-year-old male adolescent presented with bilateral orbital mass, hearing difficulty, and clinical signs of multiple cranial nerves palsy. Approximately 6 weeks later, acute myeloid leukemia was confirmed. This case alerts us that in patients with diverse sarcomatous lesions, acute myeloid leukemia presenting as myelo...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Lim SH, Nam HN, Lim KI, Jeon IS Tags: Turk J Pediatr Source Type: research

Polyarteritis nodosa in case of familial Mediterranean fever.
te D, Alpay H Abstract Gökçe İ, Altuntaş Ü, Filinte D, Alpay H. Polyarteritis nodosa in case of familial Mediterranean fever. Turk J Pediatr 2018; 60: 326-330. Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by recurrent self-limited attacks of fever accompanied by peritonitis, pleuritis, and arthritis. Protracted febrile myalgia syndrome (PFMS) is a rare form of vasculitic disease which is an uncommon dramatic manifestation of FMF, characterized by severe crippling myalgia and high fever. Polyarteritis nodosa (PAN) is a systemic necrotizing vasculitis affectin...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Gökçe İ, Altuntaş Ü, Filinte D, Alpay H Tags: Turk J Pediatr Source Type: research

An infant case of renovascular hypertension in moyamoya disease treated by angioplasty.
Abstract Guo J, Guo L, Zeng G, Tong Z, Gao X, Gu Y. An infant case of renovascular hypertension in moyamoya disease treated by angioplasty. Turk J Pediatr 2018; 60: 331-334. Here we report the treatment experience of an 18-month-old female infant case of renovascular hypertension due to moyamoya disease by angioplasty. Although renal blood flow was recovered immediately after operation, 12 months follow-up found severe restenosis which required us to perform a right renal autotransplantation. PMID: 30511550 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Guo J, Guo L, Zeng G, Tong Z, Gao X, Gu Y Tags: Turk J Pediatr Source Type: research

Chelation therapy for secondary neonatal iron over load: Lessons learned from rhesus hemolytic disease.
Abstract Khdair-Ahmad F, Aladily T, Khdair-Ahmad O, Badran EF. Chelation therapy for secondary neonatal iron overload: Lessons learned from rhesus hemolytic disease. Turk J Pediatr 2018; 60: 335-339. Secondary neonatal iron overload occurs with intrauterine and post-natal blood transfusions. Treatment with intravenous Deferoxamine was reported only in four cases in the literature. Herein we report a case of a patient born at 36 weeks of gestation, who had rhesus hemolytic disease. He developed secondary iron overload, causing liver injury, after a total of six blood transfusions: four intrauterine and 2 post-natal...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Khdair-Ahmad F, Aladily T, Khdair-Ahmad O, Badran EF Tags: Turk J Pediatr Source Type: research

Granulomatous amebic encephalitis caused by Acanthamoeba in an immuncompetent child.
er A, Bilgiç B, Salman N Abstract Sütçü M, Aktürk H, Gülümser-Şişko S, Acar M, Erol OB, Somer A, Bilgiç B, Salman N. Granulomatous amebic encephalitis caused by Acanthamoeba in an immuncompetent child. Turk J Pediatr 2018; 60: 340-343. Acanthamoeba may lead to granulomatous amebic encephalitis (GAE) with high mortality rates generally in patients with immunosupression and/or chronic disease. Here, we present a rare GAE case, who was a previously healthy child. A Georgian 9 year old boy presented with focal seizure on his left arm and confusion. Since computed tomogra...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Sütçü M, Aktürk H, Gülümser-Şişko S, Acar M, Erol OB, Somer A, Bilgiç B, Salman N Tags: Turk J Pediatr Source Type: research

Arthropathy-like findings and a carpal tunnel syndrome as the presenting features of Scheie syndrome: Three cases from the same family.
;zeri B Abstract Gökay S, Kardaş F, Kendirci M, Sözeri B. Arthropathy-like findings and a carpal tunnel syndrome as the presenting features of Scheie syndrome: Three cases from the same family. Turk J Pediatr 2018; 60: 344-347. Mucopolysaccharidosis (MPS) type I is a rare autosomal recessive disease caused by a deficiency of the lysosomal enzyme α-L-iduronidase. MPS I is divided into three subtypes based on the severity of symptoms: Hurler, Hurler-Scheie, and Scheie syndrome (severe, intermediate, and mild forms, respectively). Musculoskeletal involvement may be the only presenting sign in the pat...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Gökay S, Kardaş F, Kendirci M, Sözeri B Tags: Turk J Pediatr Source Type: research

Arrhythmia in thiamine responsive megaloblastic anemia syndrome.
We present cardiac features of five patients with TRMAS. Five patients had macrocytic anemia, diabetes mellitus, and sensorineural deafness. Two siblings had also optic atrophy. SLC19A2 gene mutation was shown in all patients. Two patients developed supraventricular tachycardia during an episode of diabetic ketoacidosis. Five patients had absent P waves on baseline electrocardiography, and one patient had additional low QRS voltage. None of the patients had structural heart disease. Discontinuation of thiamine treatment appears to trigger supraventricular tachycardia episodes at puberty. PMID: 30511554 [PubMed - in pr...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Argun M, Baykan A, Hatipoğlu N, Akın L, Şahin Y, Narin N, Kurtoğlu S Tags: Turk J Pediatr Source Type: research

The stress levels of parents of premature infants and related factors in Nenoatal Intensive Care Units.
ran T Abstract Çekin B, Turan T. The stress levels of parents of premature infants and related factors in Nenoatal Intensive Care Units. Turk J Pediatr 2018; 60: 117-125. The aim of this study is to determine the stress levels of parents whose premature baby are hospitalized in the neonatal intensive care unit (NICU) and to determine the factors affecting their stress. The study sample included 101 parents of premature babies in the NICU of a university hospital. Interviews were conducted with the parents. Additionally, the Parental Stress Scale: Neonatal Intensive Care Unit (PSS:NICU) was administered. Whe...
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Çekin B, Turan T Tags: Turk J Pediatr Source Type: research

Comparison between high-flow nasal oxygen cannula and conventional oxygen therapy after extubation in pediatric intensive care unit.
In conclusion, HFNC is better than COT, especially for the restoration of the respiratory and radiologic parameters. Although more expensive, the use of HFNC may have more advantages to reduce the risk of extubation failure in critically ill children compared with COT. PMID: 30325117 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Akyıldız B, Öztürk S, Ülgen-Tekerek N, Doğanay S, Görkem SB Tags: Turk J Pediatr Source Type: research

Association of dysglycemia with mortality in children receiving parenteral nutrition in pediatric intensive care unit.
Abstract Khajavi L, Khademi G, Mehramiz M, Norouzy A, Safarian M. Association of dysglycemia with mortality in children receiving parenteral nutrition in pediatric intensive care unit. Turk J Pediatr 2018; 60: 134-141. One of the most important complications of parenteral nutrition (PN) is a high incidence of hyperglycemia. The aim of this study was to assess the effect of parenteral nutrition dysglycemia on clinical outcomes among critically ill children in pediatric intensive care unit (PICU). Charts of 201 critically ill children admitted in PICU during 2012-2015 were reviewed retrospectively. We included patients who were
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Khajavi L, Khademi G, Mehramiz M, Norouzy A, Safarian M Tags: Turk J Pediatr Source Type: research