GPR56 homozygous nonsense mutation p.R271* associated with phenotypic variability in bilateral frontoparietal polymicrogyria.
üksel B, Hız-Kurul S, Cingöz S Abstract Öncü-Öner T, Ünalp A, Porsuk-Doru İ, Ağılkaya S, Güleryüz H, Saraç A, Ergüner B, Yüksel B, Hız-Kurul S, Cingöz S. GPR56 homozygous nonsense mutation p.R271* associated with phenotypic variability in bilateral frontoparietal polymicrogyria. Turk J Pediatr 2018; 60: 229-237. Polymicrogyria is a disorder of neuronal migration characterized by excessive cortical folding and partially fused gyri separated by shallow sulci. Homozygous mutations in the GPR56 gene, which regulates migration of neural precursor cells,...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Öncü-Öner T, Ünalp A, Porsuk-Doru İ, Ağılkaya S, Güleryüz H, Saraç A, Ergüner B, Yüksel B, Hız-Kurul S, Cingöz S Tags: Turk J Pediatr Source Type: research

Efficacy of rufinamide in childhood refractory epilepsy.
The objective of this study was to evaluate the reliability of rufinamide and its impact on seizure frequency in patients diagnosed with drug-resistant epilepsy, where seizures could not be controlled with `classical` antiepileptic drugs. We retrospectively reviewed the data of epileptic patients who were followed up between January 2004 and December 2014 in the Pediatric Neurology Department. Patients who were diagnosed with `drug resistant epilepsy` and treated with rufinamide were evaluated. Decrease in seizure frequency and drug side effects were assessed as parameters. A total of 38 patients (14 girls, 24 boys) with a...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Yıldız EP, Hızlı Z, Bektaş G, Ulak-Özkan M, Tatlı B, Aydınlı N, Çalışkan M, Özmen M Tags: Turk J Pediatr Source Type: research

Glycemic control and health behaviors in adolescents with type 1 diabetes.
can O, Bundak R Abstract Yetim A, Alikaşifoğlu M, Baş F, Eliaçık K, Çığ G, Erginöz E, Ercan O, Bundak R. Glycemic control and health behaviors in adolescents with type 1 diabetes. Turk J Pediatr 2018; 60: 244-254. The purpose of this study was to determine the health/health risk behaviors of a group of Turkish adolescents with type 1 diabetes (T1D) to determine the prevalence and explore the exact effect of these behaviors on glycemic control (GC). A total of 210 adolescents (age 12-20 years; diabetes duration> 6 months; no additional comorbidities), completed a self-administered questi...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Yetim A, Alikaşifoğlu M, Baş F, Eliaçık K, Çığ G, Erginöz E, Ercan O, Bundak R Tags: Turk J Pediatr Source Type: research

The influence of media on the sleep quality in adolescents.
This study was conducted to evaluate the influence of media devices on sleep quality in adolescents. Applying a descriptive design, the study was carried out with 9th, 10th and 11th grade students (N=392, 52.0% female, average age 16.04±0.86) who were attending Konya High School between the dates of January 18 and 22, 2016. Changes were seen to occur in the wake-up times of those who had either a television or a computer in their bedrooms (p
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Akçay D, Akçay BD Tags: Turk J Pediatr Source Type: research

Hereditary spherocytosis: Retrospective evaluation of 65 children.
k N, Kara A Abstract Güngör A, Yaralı N, Fettah A, Ok-Bozkaya İ, Özbek N, Kara A. Hereditary spherocytosis: Retrospective evaluation of 65 children. Turk J Pediatr 2018; 60: 264-269. Hereditary spherocytosis (HS) is a common cause of congenital hemolytic anemia in Caucasians and it could be diagnosed at any age. The aim of this study is to examine the demographic characteristics, clinical features and laboratory findings of children with HS and their complications observed during follow up. Sixty-five patients, with hereditary spherocytosis between January 2008 and September 2013, were enrolled in...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Güngör A, Yaralı N, Fettah A, Ok-Bozkaya İ, Özbek N, Kara A Tags: Turk J Pediatr Source Type: research

Advantage of the subcutaneous immunoglobulin replacement therapy in primary immunodeficient patients with or without secondary protein loss.
l;zkan F, Erol M, Tezcan İ Abstract Gür-Çetinkaya P, Çağdaş-Ayvaz DN, Öksüz AB, Ertoy A, Hayran U, Özkan F, Erol M, Tezcan İ. Advantage of the subcutaneous immunoglobulin replacement therapy in primary immunodeficient patients with or without secondary protein loss. Turk J Pediatr 2018; 60: 270-276. In recent years subcutaneous immunoglobulin is widely used for primary immunodeficient patients. Subcutaneous administration provides a more stable and higher serum immunoglobulin levels due to continuous and steady transition from lymphatics to the systemic circulation. We aimed t...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Gür-Çetinkaya P, Çağdaş-Ayvaz DN, Öksüz AB, Ertoy A, Hayran U, Özkan F, Erol M, Tezcan İ Tags: Turk J Pediatr Source Type: research

High alert medications administration errors in neonatal intensive care unit: A pediatric tertiary hospital experience.
Abstract Labib JR, Youssef MRL, Abd El Fatah SAM. High alert medications administration errors in neonatal intensive care unit: A pediatric tertiary hospital experience. Turk J Pediatr 2018; 60: 277-285. Labib JR, Youssef MRL, Abd El Fatah SAM. High alert medications administration errors in neonatal intensive care unit: A pediatric tertiary hospital experience. Turk J Pediatr 2018; 60: 277-285. This is a hospital-based descriptive cross sectional study, implemented in the NICU, at Cairo University Pediatric hospital. A convenient sample of 33 bedside NICU nurses, who agreed to participate was recruited. A valid, ...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Labib JR, Labib-Youssef MR, Fatah S Tags: Turk J Pediatr Source Type: research

Gelsolin levels in patients with bronchiolitis.
In this study, the aim was to determine the clinical predictiveness of plasma gelsolin levels (pGSN) in acute bronchiolitis. From December 2013 to May 2014, 52 patients with bronchiolitis (aged 0.05). Recent studies reported that pGSN levels can be used as a biomarker in sepsis, inflammation and injuries. In this study, we have demonstrated that pGSN level is not a predictive biomarker of bronchiolitis and its severity. Hence, we hypothesized that pGSN levels can be used in bacterial infections rather than viral infections as a biomarker. PMID: 30511541 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Hüsrevoğlu-Esen F, Altuner-Torun Y, Karakükçü Ç, Köse S, Şehriyaroğlu A, Kafadar D, Esen A, Köse M Tags: Turk J Pediatr Source Type: research

Attitudes of physicians concerning vaccines not included in the national immunization schedule.
AE, Beyazova U Abstract Çataklı T, Duyan-Çamurdan A, Aksakal-Baran FN, Güven AE, Beyazova U. Attitudes of physicians concerning vaccines not included in the national immunization schedule. Turk J Pediatr 2018; 60: 290-297. The aim of this study was to identify attitudes of family physicians and pediatricians working in sub-provinces of central Ankara concerning rotavirus (RV), human papilloma virus (HPV), meningococcal conjugate vaccine (MenACWY-MCV4) and adolescent and adult pertussis (Tdap) vaccines which are not included in the National Immunization Schedule (NIS). Questionnaires were condu...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Çataklı T, Duyan-Çamurdan A, Aksakal-Baran FN, Güven AE, Beyazova U Tags: Turk J Pediatr Source Type: research

Birth outcomes after inadvertent use of category X drugs contraindicated in pregnancy: Where is the real risk?
nar T, Vural K Abstract Öztürk Z, Ölmez E, Gürpınar T, Vural K. Birth outcomes after inadvertent use of category X drugs contraindicated in pregnancy: Where is the real risk? Turk J Pediatr 2018; 60: 298-305. Drugs contraindicated in pregnancy are medicines that should be avoided by pregnant women, since they carry a concern for teratogenicity or there is no indication for their use during pregnancy. It does not mean that exposures to these drugs always cause harm. The aim of the present study was to investigate the risk of adverse outcomes following maternal exposure to the drugs contraindic...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Öztürk Z, Ölmez E, Gürpınar T, Vural K Tags: Turk J Pediatr Source Type: research

Neonatal atrial flutter: Three cases and review of the literature.
il;etinkaya M Abstract Yılmaz-Semerci S, Bornaun H, Kurnaz D, Cebeci B, Babayiğit A, Büyükkale G, Çetinkaya M. Neonatal atrial flutter: Three cases and review of the literature. Turk J Pediatr 2018; 60: 306-309. Atrial flutter (AFl) is known to be a seldom type of fetal and neonatal arrhythmia. Although it could end in severe morbidities such as hydrops fetalis or even death, with early prenatal diagnosis and prompt therapeutic approaches the majority of AFl cases show good prognosis. Neonatal AFl might be resistant to first step therapies. Therefore, secondary agents like flecainide, amiodarone...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Yılmaz-Semerci S, Bornaun H, Kurnaz D, Cebeci B, Babayigit A, Büyükkale G, Çetinkaya M Tags: Turk J Pediatr Source Type: research

A case of steroid-resistance Hashimoto's encephalopathy presenting with sensorimotor polyneuropathy.
We report a case of steroid-resistance HE with sensorimotor polyneuropathy, as a rare presentation of this disorder. Our case showed that HE may present with sensorimotor polyneuropathy; therefore HE should be considered in the differential diagnoses of polyneuropathy. PMID: 30511545 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Emeksiz S, Kutlu NO, Alaçakır N, Çaksen H Tags: Turk J Pediatr Source Type: research

A novel mutation of the MYH7 gene in a patient with hypertrophic cardiomyopathy.
Abstract Goel N, Huddleston CB, Fiore AC. A novel mutation of the MYH7 gene in a patient with hypertrophic cardiomyopathy. Turk J Pediatr 2018; 60: 315-318. Hypertrophic cardiomyopathy (HCM) is a genetic disorder characterized by asymmetric cardiac hypertrophy due to inherited mutations in genes that encode sarcomeric proteins. MYH7, which encodes β-myosin heavy chain, is among the most commonly mutated genes in patients affected by HCM. We aimed to identify the specific mutation responsible for HCM in a six-month old Caucasian patient. NextGen DNA sequencing revealed a novel p.Ala1328Thr (A1328T) mutation of...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Goel N, Huddleston CB, Fiore AC Tags: Turk J Pediatr Source Type: research

A case of atypically located leiomyoma mimicking axillary lymphadenomegaly.
Abstract Cevizci MN, Fettah A, Kabalar ME. A case of atypically located leiomyoma mimicking axillary lymphadenomegaly. Turk J Pediatr 2018; 60: 319-321. Leiomyomas are benign smooth muscle tumors rarely seen in children and may occur anywhere in the body containing smooth muscle. Here, we report a case of a 4-year-old girl presenting with swelling in the left axillary region and with pain during arm movements. The solid mass in the axillary region was totally excised. The patient was discharged without complications on the same day. PMID: 30511547 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Cevizci MN, Fettah A, Kabalar ME Tags: Turk J Pediatr Source Type: research

A case of myeloid sarcoma presenting with an orbital mass, hearing loss, and multiple cranial neuropathies.
Abstract Lim SH, Nam HN, Lim KI, Jeon IS. A case of myeloid sarcoma presenting with an orbital mass, hearing loss, and multiple cranial neuropathies. Turk J Pediatr 2018; 60: 322-325. Primary myeloid sarcoma occurring in multiple sites; orbit, ear, brain, and spinal cord is a rare clinical entity. A 15-year-old male adolescent presented with bilateral orbital mass, hearing difficulty, and clinical signs of multiple cranial nerves palsy. Approximately 6 weeks later, acute myeloid leukemia was confirmed. This case alerts us that in patients with diverse sarcomatous lesions, acute myeloid leukemia presenting as myelo...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Lim SH, Nam HN, Lim KI, Jeon IS Tags: Turk J Pediatr Source Type: research

Polyarteritis nodosa in case of familial Mediterranean fever.
te D, Alpay H Abstract Gökçe İ, Altuntaş Ü, Filinte D, Alpay H. Polyarteritis nodosa in case of familial Mediterranean fever. Turk J Pediatr 2018; 60: 326-330. Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by recurrent self-limited attacks of fever accompanied by peritonitis, pleuritis, and arthritis. Protracted febrile myalgia syndrome (PFMS) is a rare form of vasculitic disease which is an uncommon dramatic manifestation of FMF, characterized by severe crippling myalgia and high fever. Polyarteritis nodosa (PAN) is a systemic necrotizing vasculitis affectin...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Gökçe İ, Altuntaş Ü, Filinte D, Alpay H Tags: Turk J Pediatr Source Type: research

An infant case of renovascular hypertension in moyamoya disease treated by angioplasty.
Abstract Guo J, Guo L, Zeng G, Tong Z, Gao X, Gu Y. An infant case of renovascular hypertension in moyamoya disease treated by angioplasty. Turk J Pediatr 2018; 60: 331-334. Here we report the treatment experience of an 18-month-old female infant case of renovascular hypertension due to moyamoya disease by angioplasty. Although renal blood flow was recovered immediately after operation, 12 months follow-up found severe restenosis which required us to perform a right renal autotransplantation. PMID: 30511550 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Guo J, Guo L, Zeng G, Tong Z, Gao X, Gu Y Tags: Turk J Pediatr Source Type: research

Chelation therapy for secondary neonatal iron over load: Lessons learned from rhesus hemolytic disease.
Abstract Khdair-Ahmad F, Aladily T, Khdair-Ahmad O, Badran EF. Chelation therapy for secondary neonatal iron overload: Lessons learned from rhesus hemolytic disease. Turk J Pediatr 2018; 60: 335-339. Secondary neonatal iron overload occurs with intrauterine and post-natal blood transfusions. Treatment with intravenous Deferoxamine was reported only in four cases in the literature. Herein we report a case of a patient born at 36 weeks of gestation, who had rhesus hemolytic disease. He developed secondary iron overload, causing liver injury, after a total of six blood transfusions: four intrauterine and 2 post-natal...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Khdair-Ahmad F, Aladily T, Khdair-Ahmad O, Badran EF Tags: Turk J Pediatr Source Type: research

Granulomatous amebic encephalitis caused by Acanthamoeba in an immuncompetent child.
er A, Bilgiç B, Salman N Abstract Sütçü M, Aktürk H, Gülümser-Şişko S, Acar M, Erol OB, Somer A, Bilgiç B, Salman N. Granulomatous amebic encephalitis caused by Acanthamoeba in an immuncompetent child. Turk J Pediatr 2018; 60: 340-343. Acanthamoeba may lead to granulomatous amebic encephalitis (GAE) with high mortality rates generally in patients with immunosupression and/or chronic disease. Here, we present a rare GAE case, who was a previously healthy child. A Georgian 9 year old boy presented with focal seizure on his left arm and confusion. Since computed tomogra...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Sütçü M, Aktürk H, Gülümser-Şişko S, Acar M, Erol OB, Somer A, Bilgiç B, Salman N Tags: Turk J Pediatr Source Type: research

Arthropathy-like findings and a carpal tunnel syndrome as the presenting features of Scheie syndrome: Three cases from the same family.
;zeri B Abstract Gökay S, Kardaş F, Kendirci M, Sözeri B. Arthropathy-like findings and a carpal tunnel syndrome as the presenting features of Scheie syndrome: Three cases from the same family. Turk J Pediatr 2018; 60: 344-347. Mucopolysaccharidosis (MPS) type I is a rare autosomal recessive disease caused by a deficiency of the lysosomal enzyme α-L-iduronidase. MPS I is divided into three subtypes based on the severity of symptoms: Hurler, Hurler-Scheie, and Scheie syndrome (severe, intermediate, and mild forms, respectively). Musculoskeletal involvement may be the only presenting sign in the pat...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Gökay S, Kardaş F, Kendirci M, Sözeri B Tags: Turk J Pediatr Source Type: research

Arrhythmia in thiamine responsive megaloblastic anemia syndrome.
We present cardiac features of five patients with TRMAS. Five patients had macrocytic anemia, diabetes mellitus, and sensorineural deafness. Two siblings had also optic atrophy. SLC19A2 gene mutation was shown in all patients. Two patients developed supraventricular tachycardia during an episode of diabetic ketoacidosis. Five patients had absent P waves on baseline electrocardiography, and one patient had additional low QRS voltage. None of the patients had structural heart disease. Discontinuation of thiamine treatment appears to trigger supraventricular tachycardia episodes at puberty. PMID: 30511554 [PubMed - in pr...
Source: The Turkish Journal of Pediatrics - December 5, 2018 Category: Pediatrics Authors: Argun M, Baykan A, Hatipoğlu N, Akın L, Şahin Y, Narin N, Kurtoğlu S Tags: Turk J Pediatr Source Type: research

The stress levels of parents of premature infants and related factors in Nenoatal Intensive Care Units.
ran T Abstract Çekin B, Turan T. The stress levels of parents of premature infants and related factors in Nenoatal Intensive Care Units. Turk J Pediatr 2018; 60: 117-125. The aim of this study is to determine the stress levels of parents whose premature baby are hospitalized in the neonatal intensive care unit (NICU) and to determine the factors affecting their stress. The study sample included 101 parents of premature babies in the NICU of a university hospital. Interviews were conducted with the parents. Additionally, the Parental Stress Scale: Neonatal Intensive Care Unit (PSS:NICU) was administered. Whe...
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Çekin B, Turan T Tags: Turk J Pediatr Source Type: research

Comparison between high-flow nasal oxygen cannula and conventional oxygen therapy after extubation in pediatric intensive care unit.
In conclusion, HFNC is better than COT, especially for the restoration of the respiratory and radiologic parameters. Although more expensive, the use of HFNC may have more advantages to reduce the risk of extubation failure in critically ill children compared with COT. PMID: 30325117 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Akyıldız B, Öztürk S, Ülgen-Tekerek N, Doğanay S, Görkem SB Tags: Turk J Pediatr Source Type: research

Association of dysglycemia with mortality in children receiving parenteral nutrition in pediatric intensive care unit.
Abstract Khajavi L, Khademi G, Mehramiz M, Norouzy A, Safarian M. Association of dysglycemia with mortality in children receiving parenteral nutrition in pediatric intensive care unit. Turk J Pediatr 2018; 60: 134-141. One of the most important complications of parenteral nutrition (PN) is a high incidence of hyperglycemia. The aim of this study was to assess the effect of parenteral nutrition dysglycemia on clinical outcomes among critically ill children in pediatric intensive care unit (PICU). Charts of 201 critically ill children admitted in PICU during 2012-2015 were reviewed retrospectively. We included patients who were
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Khajavi L, Khademi G, Mehramiz M, Norouzy A, Safarian M Tags: Turk J Pediatr Source Type: research

Corticosteroid phobia among parents of asthmatic children.
may Z, Güler N Abstract Özçeker D, Uçkun U, İslamova D, Tamay Z, Güler N. Corticosteroid phobia among parents of asthmatic children. Turk J Pediatr 2018; 60: 142-146. Asthma is one of the most prevalent chronic diseases among children. Its prevalence and morbidity have been rising in recent decades. Pediatric asthma causes a significant burden on families; allergen-avoidance measures, uncontrolled disease, and disease severity which are the major cost predictors of childhood asthma in Turkey. Inhaled corticosteroids (ICS) are considered as cornerstone medications in asthma management ...
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Özçeker D, Uçkun U, İslamova D, Tamay Z, Güler N Tags: Turk J Pediatr Source Type: research

Frequency of thiopurine S-methyltransferase gene variations in Turkish children with acute leukemia.
In this study we aim to determine the genotype distribution and allele frequencies of common TPMT (*2, *3A, *3B and *3C) polymorphisms in Turkish children with acute leukemia. The study population consisted of 169 patients aged between 1 and 15 years who were admitted to Losante Pediatric Hematology and Children`s Hospital with the diagnosis of acute leukemia. Genotyping of TPMT polymorphisms was screened with real-time PCR using fluorescence melting curve detection analysis. We found that the frequencies of four allelic variants of TPMT are *2 (238 G> C) (0,0%), *3A (460G> A and 719A> G) (1.7%), *3B (460G> A) ...
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Akın DF, Aşlar-Öner D, Kürekçi E, Akar N Tags: Turk J Pediatr Source Type: research

Acute pancreatitis in children: A single center experience over ten years.
In this study; we aimed to analyze the demographic characteristics, etiology, outcome and incidence of AP among hospitalized children in our center. Medical records of the children with AP since January 2005 were analyzed from hospital files (N=63). Major etiologies were systemic diseases (14.3%), trauma (11.1%), cholelithiasis (9.5%); 54% (N=34) of the patients had mild AP, while 28.6% (N=18) had moderately severe AP and 17.4% (N=11) had severe AP. Organ dysfunction was found in 11 patients (17.4%) at initial examination. During the follow-up period (68.1±24.3 months), 10 patients (15.9%) experienced 24 recurring A...
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Sağ E, Kaya G, Bahat-Özdoğan E, Karahan SC, İmamoğlu M, Sarıhan H, Çakır M Tags: Turk J Pediatr Source Type: research

Evaluation of Restless Legs syndrome and growing pains in children with familial Mediterranean f.
This study suggested that GP and RLS are not more common in pediatric FMF patients than their healthy peers. PMID: 30325122 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Altuğ-Gücenmez Ö, Makay B, Kaçar A, Ünsal E, Sarıhan H, Çakır M Tags: Turk J Pediatr Source Type: research

Speech delay in toddlers: Are they only `late talkers`?
This study presented 31 of 100 children needed further diagnostic work up and early intervention. Therefore, pediatricians should not underestimate speech delay. On the other hand, due to the fact that, the regulations to receive special education and therapy often create anxiety for the parents, we think that this system needs to be updated and special education support should be determined by the special needs of each child. PMID: 30325123 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Zengin-Akkuş P, Çelen-Yoldaş T, Kurtipek G, Özmert EN Tags: Turk J Pediatr Source Type: research

Reliability of ultrasonography and the Alvarado scoring system in acute appendicitis.
In this study, we aimed to evaluate the diagnostic performance of ultrasonography, the Alvarado score, mean platelet volume and C-reactive protein in the diagnosis of acute appendicitis. Patients admitted to the pediatric emergency department with abdominal pain who were operated on with a preliminary diagnosis of acute appendicitis were evaluated. The patients who had acute appendicitis diagnosis in the histopathological assessment were considered as the Appendicitis (App) Group, while patients who did not have acute appendicitis according to histopathology were considered as the Non-app Group. Of 200 patients assessed in...
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Yazar AS, Erdoğan S, Şahin C, Güven Ş Tags: Turk J Pediatr Source Type: research

Positional installation of contrast (PIC) and Redo-PIC cystography for diagnosis of occult vesicoureteral reflux.
Abstract Karadeniz-Cerit K, Thomas DT, Ergun R, Yıldız N, Alpay H, İnanır S, Dağlı ET, Tuğtepe H. Positional installation of contrast (PIC) and Redo-PIC cystography for diagnosis of occult vesicoureteral reflux. Turk J Pediatr 2018; 60: 180-187. To evaluate the value of Positional Installation of Contrast (PIC) and Redo-PIC cystography in patients with febrile recurrent urinary tract infection (f-UTI) where voiding cystourethrogram (VCUG) was negative. Patients with recurrent f-UTI with no reflux on VCUG referred to the outpatient clinic of Pediatric Urology, between June 2011 and June 2016 were included in...
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Karadeniz-Cerit K, Thomas DT, Ergun R, Yıldız N, Alpay H, İnanir S, Dağlı ET, Tuğtepe H Tags: Turk J Pediatr Source Type: research

Tufted angioma arising at the site of hepatitis B vaccination: A case report.
Abstract Sepaskhah M, Hajizadeh J, Sari-Aslani F, Jowkar F. Tufted angioma arising at the site of hepatitis B vaccination: A case report. Turk J Pediatr 2018; 60: 188-190. Tufted angioma is a benign vascular proliferation which presents most commonly in infants and children and could occasionally be complicated by Kasabach-Merritt syndrome. Here, we report a 4-month-old girl with erythematous firm plaque on left thigh at the site of hepatitis B vaccine injection accompanied with thrombocytopenia. Histological examination showed multiple lobules of capillary sized vascular proliferation in the dermis and subcutaneo...
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Sepaskhah M, Hajizadeh J, Sari-Aslani F, Jowkar F Tags: Turk J Pediatr Source Type: research

Percutaneous retrieval of umbilical vein catheter fragment in an infant two months after embolization.
Abstract Akın A, Bilici M, Demir F, Yılmazer MM, İpek MŞ, Kara H. Percutaneous retrieval of umbilical vein catheter fragment in an infant two months after embolization. Turk J Pediatr 2018; 60: 191-193. Umbilical vein catheterization is frequently preferred and a safe route of venous access especially in newborns. However, some cases with breaking and embolization of those catheters have been rarely reported. Herein we present a two-and-a-half-month-old infant being catheterized within first postnatal week and diagnosed to have embolization of the catheter fragment to conjunction of hepatic vein and right atri...
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Akın A, Bilici M, Demir F, Yılmazer MM, İpek MŞ, Kara H Tags: Turk J Pediatr Source Type: research

Pulmonary artery sling anomaly presenting with unilateral lung hyperinflation: A case r.
We present a one-month-old infant with dyspnea who had a hyperinflated left lung and collapsed right lung. Computed tomography (CT) angiography demonstrated pulmonary sling causing compression of proximal parts of right and left main bronchi. This case highlights the importance of three-dimensional CT angiography in evaluation of thoracic vascular anomalies associated with tracheobronchial pathologies. PMID: 30325128 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Şahin H, Pekçevik Y Tags: Turk J Pediatr Source Type: research

A rare cause of neonatal hypertension: Congenital mesoblastic nephroma.
We present a 32-week gestation infant and his histopathology reports of cellular CMN presented with refractory hypertension. PMID: 30325129 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Soyaltın E, Alaygut D, Alparslan C, Özdemir T, Çamlar SA, Mutlubaş F, Kasap-Demir B, Yavaşcan Ö Tags: Turk J Pediatr Source Type: research

Low hemoglobin A1c levels in a patient with diabetic ketoacidosis: Fulminant type 1 diabetes mellitus.
This study focused on the case of a 35-monthold boy who was referred to our clinic with the diagnosis of diabetic ketoacidosis, and later had a modest elevation in hemoglobin A1c (HbA1c) levels (6.7 %) incompatible with his significantly elevated blood glucose levels. The autoantibodies against pancreatic β-cells were negative. On the basis of these above mentioned findings, our patient was then diagnosed with fulminant type 1 diabetes mellitus. If patients with diabetic ketoacidosis have no elevation in HbA1c levels, they should be assessed for possible clinical factors that can lead to lower detectable levels of HbA...
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Keskin M, Savaş-Erdeve Ş, Çetinkaya S, Aycan Z Tags: Turk J Pediatr Source Type: research

A `glue sniffer` teenager with anuric renal failure and hepatitis.
In this report, a 16-year-old boy presented with jaundice, nausea, vomiting and reduced urine output. He developed severe acute renal/hepatic damage due to abuse of gas products. Since toluene is the main toxic agent involved in glue sniffing which is metabolized to hippuric acid, the present case was treated with continuous hemodiafiltration, plasma exchange and conservative therapy to eliminate hippuric acid. The jaundice gradually disappeared, he had complete recovery of renal/hepatic functions in ten days. We aimed to increase the awareness among emergency physicians that ``glue sniffing` should be considered in the di...
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Yurtseven A, Türksoylu M, Yazıcı P, Karapınar B, Saz EU Tags: Turk J Pediatr Source Type: research

Acute renal failure due to severe hypercalcemia and nephrocalcinosis treated with two doses of pamidronate in an infant with Williams-Beuren syndrome.
We present a 23-month-old girl with WBS (confirmed with fluorescent in situ hybridization probes) who presented with acute renal failure with severe symptomatic hypercalcemia and nephrocalcinosis, which responded to two infusions of pamidronate. PMID: 30325132 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Baştuğ F, Nalçacıoğlu H, Baş VN, Tekatlı-Çelik B, Çetinkaya H, Yel S Tags: Turk J Pediatr Source Type: research

The first pediatric case of leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL) from Turkey.
R, Arıcan P, Gençpınar P Abstract Çavuşoğlu D, Olgaç-Dündar N, Öztekin Ö, Özdemir TR, Arıcan P, Gençpınar P. The first pediatric case of leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL) from Turkey. Turk J Pediatr 2018; 60: 216-220. Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL) is defined as an autosomal recessive inheritance disorder characterized by slowly progressive cerebellar, pyramidal and dorsal column dysfunction. The diagnosis is based on specific magnetic resonanc...
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Çavuşoğlu D, Olgaç-Dündar N, Öztekin Ö, Özdemir TR, Arıcan P, Gençpınar P Tags: Turk J Pediatr Source Type: research

Stuck tunneled central venous catheters in children: Four cases removed by angiography assistance.
We present four cases of fixated cuffed tunneled catheters. Three children had acute lymphoblastic leukemia and one had an immunodeficiency syndrome. All catheters were made from polyurethane. Indwelling times were 12-24 months. All patients` catheters were removed with great difficulty by trans-femoral access. The angiography-assisted technique is safe and easily-applied for the removal of stuck catheters in pediatric patients. These cases raise important questions concerning the maximum indwelling time and the choice of catheter material when implanting permanent central venous catheters (CVCs) in children. PMID: 30...
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Ateş U, Taştekin NY, Mammadov F, Ergün E, Göllü G, Can ÖS, Uçar T, Bingöl-Koloğlu M, Yağmurlu A, Aktuğ T Tags: Turk J Pediatr Source Type: research

Ogilvie syndrome presenting with septic shock.
We report a 10-year-old child with an unremarkable past history who presented with septic shock including hypotension, prolonged capillary refill time, decreased urine output (
Source: The Turkish Journal of Pediatrics - October 18, 2018 Category: Pediatrics Authors: Özsoylu S, Akyıldız BN, Dursun A Tags: Turk J Pediatr Source Type: research

Clinical and molecular evaluation of 16 patients with Rett syndrome.
This study, in a group of patients from a single tertiary center, aimed to evaluate the efficiency of clinical diagnosis and to see if there was a diagnostic delay. A second aim was to investigate genotype-phenotype correlations, based on Pineda scores. In this study, sixteen patients with a median age of 6.5 years (2.5-22 years) were included, following molecular confirmation of clinical diagnosis. The median age at the onset of symptoms and the median age at clinical diagnosis was 1.5 years and 2.5 years, respectively, the difference being statistically significant. Considering the Rett syndrome diagnostic criteria, init...
Source: The Turkish Journal of Pediatrics - August 15, 2018 Category: Pediatrics Authors: Zengin-Akkuş P, Taşkıran EZ, Kabaçam S, Şimşek-Kiper PÖ, Haliloğlu G, Boduroğlu K, Utine GE Tags: Turk J Pediatr Source Type: research

The value of nasopharyngeal aspirate, gastric aspirate and bronchoalveolar lavage fluid in the diagnosis of childhood tuberculosis.
Yüksel M Abstract Çakır E, Özdemir A, Daşkaya H, Umutoğlu T, Yüksel M. The value of nasopharyngeal aspirate, gastric aspirate and bronchoalveolar lavage fluid in the diagnosis of childhood tuberculosis. Turk J Pediatr 2018; 60: 10-13. Pulmonary tuberculosis (TB) is an important cause of morbidity and mortality especially in developing countries. A definitive microbiologic confirmation of Mycobacterium tuberculosis is important in the diagnosis of childhood TB. We aimed to compare the diagnostic value of nasopharyngeal aspirate (NPA), gastric aspirate (GA) and bronchoalveolar lavage (BAL) s...
Source: The Turkish Journal of Pediatrics - August 15, 2018 Category: Pediatrics Authors: Çakır E, Özdemir A, Daşkaya H, Umutoğlu T, Yüksel M Tags: Turk J Pediatr Source Type: research

C1q nephropathy among children with nephrotic syndrome: Ten-year experience from a pediatric nephrology unit.
Abstract Abu-Shahin N, Al-Khader A, Qattan D, Akl K. C1q nephropathy among children with nephrotic syndrome: Ten-year experience from a pediatric nephrology unit. Turk J Pediatr 2018; 60: 14-21. C1q nephropathy (C1qN) is a rare glomerulopathy mostly seen in children, and presents with nephrotic syndrome (NS). Diagnosis depends on immunoflourescence or immunohistochemical C1q mesangial deposition, excluding other immune-mediated diseases. We retrospectively investigated C1qN incidence, clinicopathological features, and outcome among pediatric NS in our institution.Clinical data, microscopic slides and corresponding...
Source: The Turkish Journal of Pediatrics - August 15, 2018 Category: Pediatrics Authors: Abu-Shahin N, Al-Khader A, Qattan D, Akl K Tags: Turk J Pediatr Source Type: research

Investigation of the frequency of iron insufficiency among infants in a population in which routine iron supplementation is implemented.
, Arsan S Abstract Çullas-İlarslan NE, Günay F, İleri DT, Elhan AH, Ertem M, Arsan S. Investigation of the frequency of iron insufficiency among infants in a population in which routine iron supplementation is implemented. Turk J Pediatr 2018; 60: 22-31. Iron deficiency anemia (IDA) represents the most common cause of anemia worldwide. Because of potential irreversible neurodevelopmental impairment, its prevention during infancy is essential. We aimed to investigate the frequency of iron insufficiency among infants in a population which routine iron supplementation is implemented; and to examine rela...
Source: The Turkish Journal of Pediatrics - August 15, 2018 Category: Pediatrics Authors: Çullas-İlarslan NE, Günay F, İleri DT, Elhan AH, Ertem M, Arsan S Tags: Turk J Pediatr Source Type: research

Psychiatric morbidity and quality of life in children and adolescents with cystic fibrosis.
In conclusion, CF is associated with poorer QOL in childhood. In order to improve quality of life in CF, the psychiatric conditions of children and adolescents should also be evaluated and their follow-up and treatment should involve a multidisciplinary team approach. PMID: 30102477 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 15, 2018 Category: Pediatrics Authors: Şenses-Dinç G, Özçelik U, Çak T, Doğru-Ersöz D, Çöp E, Yalçın E, Çengel-Kültür E, Pekcan S, Kiper N, Ünal F Tags: Turk J Pediatr Source Type: research

Allergen variability and house dust mite sensitivity in pre-school children with allergic complaints.
kman S, Can D Abstract Yazıcı S, Güneş S, Kurtuluş-Çokboz M, Kemer Ö, Baranlı G, Aşık-Akman S, Can D. Allergen variability and house dust mite sensitivity in pre-school children with allergic complaints. Turk J Pediatr 2018; 60: 41-49. The increase in the prevalence of allergic diseases in pre-school children who are often at home may be due to an increase in house dust mite sensitivity, which is rarely expected in this age group. In our study, it was aimed to investigate allergen sensitivities, especially house dust mite sensitivity in pre-school children with allergic disease complaints b...
Source: The Turkish Journal of Pediatrics - August 15, 2018 Category: Pediatrics Authors: Yazıcı S, Güneş S, Kurtuluş-Çokboz M, Kemer Ö, Baranlı G, Aşık-Akman S, Can D Tags: Turk J Pediatr Source Type: research

Knowledge levels related to allergen specific immunotherapy and perspectives of parents whose children were diagnosed with asthma and/or allergic rhinitis in Turkey.
araman Ö, Uzuner N Abstract Işık S, Çağlayan-Sözmen Ş, Asilsoy S, Kılıçarslan SK, Anal Ö, Karaman Ö, Uzuner N. Knowledge levels related to allergen specific immunotherapy and perspectives of parents whose children were diagnosed with asthma and/or allergic rhinitis in Turkey. Turk J Pediatr 2018; 60: 50-55. In the present study, we aimed to evaluate the knowledge levels and perspectives about allergen specific immunotherapy (ASI) of parents whose children were diagnosed with asthma and/or allergic rhinitis with positive skin prick test. The study was conducted between Septem...
Source: The Turkish Journal of Pediatrics - August 15, 2018 Category: Pediatrics Authors: Işık S, Çağlayan-Sözmen Ş, Asilsoy S, Kılıçarslan SK, Anal Ö, Karaman Ö, Uzuner N Tags: Turk J Pediatr Source Type: research

Outbreak of varicella in preschool children despite one-dose vaccination.
This study was carried out during a varicella outbreak in 3 preschools in İzmir, Turkey, in April 2016. Using questionnaires, data including children`s medical and vaccination histories were collected from their parents. Attack rates in vaccinated and unvaccinated children were calculated and the analyses of vaccine effectiveness and of risk factors for breakthrough disease were conducted. A total of 124 children were enrolled in the study. Of the 124 children, 77 (62%) had received 1-dose varicella vaccine before the outbreak. Varicella developed in 34 of 124 children during the outbreak, and 18 of them (53%) had breakth...
Source: The Turkish Journal of Pediatrics - August 15, 2018 Category: Pediatrics Authors: Kurugöl Z, Gökçe Ş Tags: Turk J Pediatr Source Type: research

Assessment of central venous catheterization and complications in a tertiary pediatric intensive care unit.
baz D Abstract Tolunay İ, Yıldızdaş RD, Elçi H, Alabaz D. Assessment of central venous catheterization and complications in a tertiary pediatric intensive care unit. Turk J Pediatr 2018; 60: 63-69. In catheter-using units as pediatric intensive care, it is important to know the complications that may occur during the insertion and use of central venous catheterization (CVC), and to take appropriate measures in order to reduce the mortality and morbidity of critical patients. The aim of this study was to evaluate CVC and catheter related complications in our tertiary pediatric intensive care unit. For th...
Source: The Turkish Journal of Pediatrics - August 15, 2018 Category: Pediatrics Authors: Tolunay İ, Yıldızdaş RD, Elçi H, Alabaz D Tags: Turk J Pediatr Source Type: research