Health insurance status and outcomes in children, adolescents, and young adults: a systematic review and meta-analysis
CONCLUSIONS: The findings of this review suggest that a lack of or insufficient insurance is related to all-cause mortality of AYAs with malignant cancers. Strategies aimed at identifying causality and reducing disparities are warranted.PMID:34449136 | DOI:10.24953/turkjped.2021.04.001 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Congyang Huang Hanshan Liu Honglian Hu Li Jia Suyun Hu Source Type: research

IgE mediated food allergy in Turkey: different spectrum, similar outcome
CONCLUSIONS: The FA spectrum of Turkish children and adolescents differs from many regions of the world with high rates of TN (hazelnut, Anacardia nuts), seed (sesame, pumpkin seed) and lentils, and low rates of soy, peanut and seafood allergies. However, resolution, emergence and persistence of allergies and comorbidities are similar, which points to the limited role of the environment in the outcome.PMID:34449137 | DOI:10.24953/turkjped.2021.04.002 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Ay şegül Akarsu Melike Ocak Gizem K öken Ümit Murat Şahiner Özge Soyer B ülent Enis Şekerel Source Type: research

Enablers and barriers for enteral feeding with mother`s own milk in preterm very low birth weight infants in a tertiary care neonatal intensive care unit
CONCLUSIONS: ELBW infants and IUGR infants are susceptible to low MOM feeding. The total of milk expressions in the first 3 days, number of night expressions in the first week, maternal visits on day 1 and the average MOM amount in the first 2 weeks are enablers for MOM feeding.PMID:34449138 | DOI:10.24953/turkjped.2021.04.003 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Dattatray Kulkarni Srinivas Murki Dinesh Pawale Soumya Jena Deepak Sharma Venkateshwarlu Vardhelli Venkat Kallem Tanveer Bashir Vidhyadhara Naik Sai Kiran Source Type: research

The performance of shear wave elastography on evaluating liver changes in obese and overweight children
Turk J Pediatr. 2021;63(4):575-583. doi: 10.24953/turkjped.2021.04.004.ABSTRACTBACKGROUND: Real time shear-wave elastography (SWE) is a non-invasive imaging method which can quantitatively assess liver stiffness. Obesity and its complication are increasing with improving lifestyles in our century. We evaluated the performance of SWE for detecting liver changes (fatty liver, steatohepatitis) in obese and overweight children, in addition to this, we determined the diagnostic accuracy and clinical usefulness of SWE in non-alcoholic fatty liver disease (NAFLD).METHODS: Obese and overweight 41 children within the age range of 6...
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Neslihan Özkul Sağlam Sema Aksoy Selcen Yaro ğlu Kazancı Figen Palab ıyık Sad ık Sami Hatipoğlu Ercan İnci Source Type: research

Developmental parameters and physical fitness in preschool children with Minor Neurological Dysfunction
Turk J Pediatr. 2021;63(4):584-593. doi: 10.24953/turkjped.2021.04.005.ABSTRACTBACKGROUND: The preschool years constitute a critical period during which significant changes are experienced in the acquisition of locomotor skills due to maturation of the nervous system. Our aim was to investigate the developmental parameters and physical fitness in preschool children with Minor Neurological Dysfunction (MND).METHODS: The study was carried out in 212 preschool children without any known health problems. Sociodemographic characteristics of children were recorded. Denver Developmental Screening Test (DDST) II, Touwen Neurologic...
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Halil Alkan Akmer Mutlu G öknur Haliloğlu Source Type: research

Expression of MicroRNA 146a, 155, 181 and 223 in febrile seizure
CONCLUSIONS: miRNAs-146a, -181a, -155 and -223 may be involved in FS pathogenesis. Altered miRNA expression levels might be an adaptive response to inflammation. New therapeutic approaches might be developed based on miRNA expressions in children with FS.PMID:34449141 | DOI:10.24953/turkjped.2021.04.006 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: K ürşat Bora Çarman Yasemin Karal G ül Gülen Mert Arzu Ekici Peren Perk Didem Arslanta ş Coskun Yarar Ener Çağrı Dinleyici Source Type: research

Developmental evaluation in children experiencing febrile convulsions
The objective of this study was to determine the effect of febrile convulsion (FC) on neuromotor development.METHODS: Data of 325 patients, who were followed up at our outpatient clinic and diagnosed with FC between January 2012 and December 2018, were retrospectively evaluated. Of these patients, 203 underwent the Denver Developmental Screening Test II (DDST II) and were included in the study as the patient group and 100 healthy children as the control group.RESULTS: Of the study group, 84 (41.4%) were girls and 119 (58.6%) were boys (B/G: 1.4). Of all patients, 163 (80.3%) were diagnosed with simple FC, 22 (10.8%) with c...
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Rojan İpek Khatuna Makharoblidze Bur çin Gönüllü Polat Meltem Çobanoğulları Direk Didem Derici Y ıldırım Mustafa K ömür Çetin Okuyaz Source Type: research

Clinical profile and long-term outcome of the first seizures in children
This study aims to identify the clinical profile and outcome of first seizures in children.METHODS: Children who presented to the pediatric neurology outpatient clinic and pediatric emergency service with a first-time seizure and aged one month through 18 years old were enrolled to the study. At the time of the study, enrolled children were categorized into three study groups according to seizure characteristics: febrile seizure, nonfebrile-provoked seizure and, unprovoked seizure.RESULTS: The study group consisted of 138 children. Of the 138 patients, 60 (43%) had febrile first seizures, 23 (17%) had nonfebrile-provoked f...
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: P ınar Arıcan Hakan Salman Nihal Olga ç Dündar Source Type: research

The causes of parental vaccine refusal: results of a survey from Giresun, Turkey
CONCLUSIONS: Primary healthcare providers, who are in close contact with parents, have an important role to provide the right health information. Various in-service training can be provided to improve the communication skills of healthcare providers. In these training sessions, besides comprehensive information about vaccines, it should be aimed to provide parents with the ability to understand their concerns, to approach them sensitively and to present the information they need effectively.PMID:34449144 | DOI:10.24953/turkjped.2021.04.009 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Özlem Terzi Elif Nur G ülen Cihad D ündar Source Type: research

Determining the effect of time dependent and time independent factors on pneumonia of children under five in North west Ethiopia
CONCLUSIONS: In northwest Ethiopia, weight, residence, previous disease history, breastfeeding and temperature are significant factors of pneumonia among children under five. The effectiveness of treatments was dependent on the number of times children visited the hospital. A significant variation of baseline pneumonia status among under five pneumonia patient children was noted in the hospital.PMID:34449145 | DOI:10.24953/turkjped.2021.04.010 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Lijalem Melie Tesfaw Muluwerk Ayele Derebe Haile Mekonnen Fenta Source Type: research

Treatment results of modified BFM protocol in pediatric high-risk Burkitt lymphoma
CONCLUSIONS: The administration of the reduced dose of methotrexate seems to not compromise treatment success nor increase the risk of CNS recurrence in high-risk BL without CNS involvement. The limitation of the study is that it is not randomized. Our treatment scheme might be considered for centers without methotrexate measurement facility.PMID:34449146 | DOI:10.24953/turkjped.2021.04.011 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Sema Vural Dildar Bahar Gen ç Rejin Kebudi Öner Doğan Serap Karaman Source Type: research

Effects of lockdown during corona pandemic on children with neurodevelopmental disorders-A questionnaire-based survey
CONCLUSIONS: To conclude, children with NDD and their parents were significantly affected by Corona pandemicrelated lockdown. Institutional therapy discontinuation, behavioural deterioration (especially among ASD and ADHD) and parental stress were prominent challenges whereas parental motivation and reliance on homebased therapy were the positive highlights. The survey points to the role of regular parent-administered homebased therapy in children with NDD, especially to tide over similar unexpected adverse scenarios.PMID:34449147 | DOI:10.24953/turkjped.2021.04.012 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Jyotindra Narayan Goswami Vishal Sondhi Ashish Kumar Simalti Manu Bamal Shuvendu Roy Source Type: research

Asthma and risk factors in the first 6 years of life in a population-based cohort
CONCLUSIONS: The prevalence of asthma at six years of age was higher than that of other studies. Prevention of infections at an early age and during pregnancy can reduce the prevalence of asthma.PMID:34449148 | DOI:10.24953/turkjped.2021.04.013 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Ay şe Şenay Şaşihüseyinoğlu Dilek Özcan Derya Ufuk Alt ıntaş Source Type: research

Assessment of sleep in children with periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome
This study aimed to investigate sleep patterns and possible factors that are associated with sleep disturbances among children with PFAPA syndrome.METHODS: Sixty-two patients with PFAPA and 68 age and sex matched healthy controls were enrolled in the study. Patients who had an attack during the former 2 weeks were not included. Demographic and anthropometric data, duration of fever episodes, laboratory results, and clinical manifestations of patients were recorded. The Children`s Sleep Habits Questionnaire was administered.RESULTS: The total sleep scores of patients with PFAPA were significantly higher than the control gro...
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Ay şin Nalbantoğlu Bur çin Nalbantoğlu Source Type: research

Cost of illness of RSV infection in a middle-income tropical country
CONCLUSION: The infection by RSV in Colombia generates a high economic burden on the health system. Generating comprehensive data on healthcare resource use and costs associated with RSV will help to provide valuable information for the development of cost-effectiveness models, and help guide prevention strategies against RSV.PMID:34449150 | DOI:10.24953/turkjped.2021.04.015 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Jefferson Antonio Buend ía Diana Guerrero Patino Denis Sinisterra Source Type: research

Timeliness of postnatal surgery in newborns with open neural tube defects: a single center experience
CONCLUSIONS: Our study appears to favor the early repair of NTD`s within the first 24 hours of life. Such an approach may reduce the risk of infectious and neurological complications significantly.PMID:34449151 | DOI:10.24953/turkjped.2021.04.016 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Ayhan Pekta ş Mehmet Gazi Boyac ı Hilal Koyuncu Mine Kanat Pekta ş Ahmet Af şin Kundak Source Type: research

Clinical and molecular characteristics of carnitineacylcarnitine translocase deficiency with c.270delC and a novel c.408C & gt;A variant
CONCLUSIONS: All three cases died despite a very intensive therapy. Based on our experience with these three cases, it can be said that CACTD has a relatively poor prognosis, molecular studies are of most importance in suspected cases for the final diagnosis and such studies might be of help while giving genetic counselling and guidance to parents for future pregnancies.PMID:34449152 | DOI:10.24953/turkjped.2021.04.017 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Berrak Bilginer G ürbüz Didem Y ücel Yılmaz R ıza Köksal Özgül Can Ko şukcu Ali Dursun Hatice Serap Sivri Turgay Co şkun Ay şegül Tokatlı Source Type: research

Outbreak of late-onset Group B Streptococcal disease with serotype Ib in a Neonatal Intensive Care Unit
CONCLUSION: Preterm delivery and VLBW are associated with an increased risk of invasive late-onset GBS infection. This report underscores the ongoing risk of nosocomial transmission of GBS in the NICU.PMID:34449153 | DOI:10.24953/turkjped.2021.04.018 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Hiroko Horie-Ota Kazushige Ikeda Source Type: research

Whole exome sequencing identifies a novel variant in ABCA3 in an individual with fatal congenital surfactant protein deficiency
CONCLUSIONS: We consider that this case report contributes to the literature on RDS by showing the presence of c.3677 T> C (p.Leu1226Pro), a new homozygous variant of ABCA3 in our patient.PMID:34449154 | DOI:10.24953/turkjped.2021.04.019 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Hayrunnisa Bekis Bozkurt Yavuz Şahin Source Type: research

A very rare cause of protein losing enteropathy: Gaucher disease
CONCLUSIONS: PLE is a devastating and life threatening complication of GD developing despite long term use of high dose ERT. Clinicians should be alert for this complication particularly in GD patients presenting with progressive abdominal distension, edema, ascites and diarrhea or in patients who have already developed mesenteric lymphadenopathies. Timely diagnosis may allow early intervention with previously suggested surgical or medical treatment options. Although there is no specific and effective treatment, surgical and aggressive medical interventions in addition to ERT were reported to relieve diarrhea and halt prog...
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Mehmet Akif G öktaş Ersin G ümüş H ülya Demir Hayriye H ızarcıoğlu Gülşen İnci Nur Saltık-Temizel Hasan Özen Şafak Güçer Aysel Y üce Source Type: research

Severe isolated sulfide oxidase deficiency with a novel mutation
CONCLUSION: The mutation identified in our patient causes severe ISOD. Early diagnosis of ISOD is essential for accurate genetic counseling and achieving prenatal diagnosis. Screening for urinary sulfite in patients with neonatal or early infantile onset seizures, developmental delay, microcephaly and cystic encephalomalacia in neuroimaging mimicking HIE helps in early diagnosis.PMID:34449156 | DOI:10.24953/turkjped.2021.04.021 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Meri ç Ergene Nuriye Yarar Elif Perihan Öncel Taner Sezer B üşranur Çavdarlı İsmail Zafer Ecevit Halil İbrahim Aydın Source Type: research

Massive true thymic hyperplasia in a 3-month-old infant: case report and literature review
CONCLUSIONS: By reviewing the literature, there were only 10 cases with MTTH reported between 1975 and 2020 for children aged
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Min Yang Lin Zeng Yi Ji Bo Xiang Zhi-Cheng Xu Source Type: research

Facial colliculus syndrome due to a Herpes simplex virus infection following Herpes labialis
CONCLUSION: Facial colliculus syndrome is rare and the treatment is based on etiology.PMID:34449158 | DOI:10.24953/turkjped.2021.04.023 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Muhittin Bodur Rabia T ütüncü Toker Abdullah Hakan Özmen Mehmet Sait Okan Source Type: research

Intranasal supernumerary tooth in a child: a case report
CONCLUSIONS: Detection of supernumerary teeth in the nasal cavity of children without symptoms is difficult, and it can be delayed; although the child, in this case, had nonspecific nasal symptoms, supernumerary teeth was not considered in the diagnosis. This case report raises awareness and provides evidence for the clinical characterization and optimal treatment of supernumerary teeth in children.PMID:34449159 | DOI:10.24953/turkjped.2021.04.024 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Yoon Seok Choi Yong-Dae Kim Chang Hoon Bae Hyung Gyun Na Source Type: research

Health insurance status and outcomes in children, adolescents, and young adults: a systematic review and meta-analysis
CONCLUSIONS: The findings of this review suggest that a lack of or insufficient insurance is related to all-cause mortality of AYAs with malignant cancers. Strategies aimed at identifying causality and reducing disparities are warranted.PMID:34449136 | DOI:10.24953/turkjped.2021.04.001 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Congyang Huang Hanshan Liu Honglian Hu Li Jia Suyun Hu Source Type: research

IgE mediated food allergy in Turkey: different spectrum, similar outcome
CONCLUSIONS: The FA spectrum of Turkish children and adolescents differs from many regions of the world with high rates of TN (hazelnut, Anacardia nuts), seed (sesame, pumpkin seed) and lentils, and low rates of soy, peanut and seafood allergies. However, resolution, emergence and persistence of allergies and comorbidities are similar, which points to the limited role of the environment in the outcome.PMID:34449137 | DOI:10.24953/turkjped.2021.04.002 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Ay şegül Akarsu Melike Ocak Gizem K öken Ümit Murat Şahiner Özge Soyer B ülent Enis Şekerel Source Type: research

Enablers and barriers for enteral feeding with mother`s own milk in preterm very low birth weight infants in a tertiary care neonatal intensive care unit
CONCLUSIONS: ELBW infants and IUGR infants are susceptible to low MOM feeding. The total of milk expressions in the first 3 days, number of night expressions in the first week, maternal visits on day 1 and the average MOM amount in the first 2 weeks are enablers for MOM feeding.PMID:34449138 | DOI:10.24953/turkjped.2021.04.003 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Dattatray Kulkarni Srinivas Murki Dinesh Pawale Soumya Jena Deepak Sharma Venkateshwarlu Vardhelli Venkat Kallem Tanveer Bashir Vidhyadhara Naik Sai Kiran Source Type: research

The performance of shear wave elastography on evaluating liver changes in obese and overweight children
Turk J Pediatr. 2021;63(4):575-583. doi: 10.24953/turkjped.2021.04.004.ABSTRACTBACKGROUND: Real time shear-wave elastography (SWE) is a non-invasive imaging method which can quantitatively assess liver stiffness. Obesity and its complication are increasing with improving lifestyles in our century. We evaluated the performance of SWE for detecting liver changes (fatty liver, steatohepatitis) in obese and overweight children, in addition to this, we determined the diagnostic accuracy and clinical usefulness of SWE in non-alcoholic fatty liver disease (NAFLD).METHODS: Obese and overweight 41 children within the age range of 6...
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Neslihan Özkul Sağlam Sema Aksoy Selcen Yaro ğlu Kazancı Figen Palab ıyık Sad ık Sami Hatipoğlu Ercan İnci Source Type: research

Developmental parameters and physical fitness in preschool children with Minor Neurological Dysfunction
Turk J Pediatr. 2021;63(4):584-593. doi: 10.24953/turkjped.2021.04.005.ABSTRACTBACKGROUND: The preschool years constitute a critical period during which significant changes are experienced in the acquisition of locomotor skills due to maturation of the nervous system. Our aim was to investigate the developmental parameters and physical fitness in preschool children with Minor Neurological Dysfunction (MND).METHODS: The study was carried out in 212 preschool children without any known health problems. Sociodemographic characteristics of children were recorded. Denver Developmental Screening Test (DDST) II, Touwen Neurologic...
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Halil Alkan Akmer Mutlu G öknur Haliloğlu Source Type: research

Expression of MicroRNA 146a, 155, 181 and 223 in febrile seizure
CONCLUSIONS: miRNAs-146a, -181a, -155 and -223 may be involved in FS pathogenesis. Altered miRNA expression levels might be an adaptive response to inflammation. New therapeutic approaches might be developed based on miRNA expressions in children with FS.PMID:34449141 | DOI:10.24953/turkjped.2021.04.006 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: K ürşat Bora Çarman Yasemin Karal G ül Gülen Mert Arzu Ekici Peren Perk Didem Arslanta ş Coskun Yarar Ener Çağrı Dinleyici Source Type: research

Developmental evaluation in children experiencing febrile convulsions
The objective of this study was to determine the effect of febrile convulsion (FC) on neuromotor development.METHODS: Data of 325 patients, who were followed up at our outpatient clinic and diagnosed with FC between January 2012 and December 2018, were retrospectively evaluated. Of these patients, 203 underwent the Denver Developmental Screening Test II (DDST II) and were included in the study as the patient group and 100 healthy children as the control group.RESULTS: Of the study group, 84 (41.4%) were girls and 119 (58.6%) were boys (B/G: 1.4). Of all patients, 163 (80.3%) were diagnosed with simple FC, 22 (10.8%) with c...
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Rojan İpek Khatuna Makharoblidze Bur çin Gönüllü Polat Meltem Çobanoğulları Direk Didem Derici Y ıldırım Mustafa K ömür Çetin Okuyaz Source Type: research

Clinical profile and long-term outcome of the first seizures in children
This study aims to identify the clinical profile and outcome of first seizures in children.METHODS: Children who presented to the pediatric neurology outpatient clinic and pediatric emergency service with a first-time seizure and aged one month through 18 years old were enrolled to the study. At the time of the study, enrolled children were categorized into three study groups according to seizure characteristics: febrile seizure, nonfebrile-provoked seizure and, unprovoked seizure.RESULTS: The study group consisted of 138 children. Of the 138 patients, 60 (43%) had febrile first seizures, 23 (17%) had nonfebrile-provoked f...
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: P ınar Arıcan Hakan Salman Nihal Olga ç Dündar Source Type: research

The causes of parental vaccine refusal: results of a survey from Giresun, Turkey
CONCLUSIONS: Primary healthcare providers, who are in close contact with parents, have an important role to provide the right health information. Various in-service training can be provided to improve the communication skills of healthcare providers. In these training sessions, besides comprehensive information about vaccines, it should be aimed to provide parents with the ability to understand their concerns, to approach them sensitively and to present the information they need effectively.PMID:34449144 | DOI:10.24953/turkjped.2021.04.009 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Özlem Terzi Elif Nur G ülen Cihad D ündar Source Type: research

Determining the effect of time dependent and time independent factors on pneumonia of children under five in North west Ethiopia
CONCLUSIONS: In northwest Ethiopia, weight, residence, previous disease history, breastfeeding and temperature are significant factors of pneumonia among children under five. The effectiveness of treatments was dependent on the number of times children visited the hospital. A significant variation of baseline pneumonia status among under five pneumonia patient children was noted in the hospital.PMID:34449145 | DOI:10.24953/turkjped.2021.04.010 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Lijalem Melie Tesfaw Muluwerk Ayele Derebe Haile Mekonnen Fenta Source Type: research

Treatment results of modified BFM protocol in pediatric high-risk Burkitt lymphoma
CONCLUSIONS: The administration of the reduced dose of methotrexate seems to not compromise treatment success nor increase the risk of CNS recurrence in high-risk BL without CNS involvement. The limitation of the study is that it is not randomized. Our treatment scheme might be considered for centers without methotrexate measurement facility.PMID:34449146 | DOI:10.24953/turkjped.2021.04.011 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Sema Vural Dildar Bahar Gen ç Rejin Kebudi Öner Doğan Serap Karaman Source Type: research

Effects of lockdown during corona pandemic on children with neurodevelopmental disorders-A questionnaire-based survey
CONCLUSIONS: To conclude, children with NDD and their parents were significantly affected by Corona pandemicrelated lockdown. Institutional therapy discontinuation, behavioural deterioration (especially among ASD and ADHD) and parental stress were prominent challenges whereas parental motivation and reliance on homebased therapy were the positive highlights. The survey points to the role of regular parent-administered homebased therapy in children with NDD, especially to tide over similar unexpected adverse scenarios.PMID:34449147 | DOI:10.24953/turkjped.2021.04.012 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Jyotindra Narayan Goswami Vishal Sondhi Ashish Kumar Simalti Manu Bamal Shuvendu Roy Source Type: research

Asthma and risk factors in the first 6 years of life in a population-based cohort
CONCLUSIONS: The prevalence of asthma at six years of age was higher than that of other studies. Prevention of infections at an early age and during pregnancy can reduce the prevalence of asthma.PMID:34449148 | DOI:10.24953/turkjped.2021.04.013 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Ay şe Şenay Şaşihüseyinoğlu Dilek Özcan Derya Ufuk Alt ıntaş Source Type: research

Assessment of sleep in children with periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome
This study aimed to investigate sleep patterns and possible factors that are associated with sleep disturbances among children with PFAPA syndrome.METHODS: Sixty-two patients with PFAPA and 68 age and sex matched healthy controls were enrolled in the study. Patients who had an attack during the former 2 weeks were not included. Demographic and anthropometric data, duration of fever episodes, laboratory results, and clinical manifestations of patients were recorded. The Children`s Sleep Habits Questionnaire was administered.RESULTS: The total sleep scores of patients with PFAPA were significantly higher than the control gro...
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Ay şin Nalbantoğlu Bur çin Nalbantoğlu Source Type: research

Cost of illness of RSV infection in a middle-income tropical country
CONCLUSION: The infection by RSV in Colombia generates a high economic burden on the health system. Generating comprehensive data on healthcare resource use and costs associated with RSV will help to provide valuable information for the development of cost-effectiveness models, and help guide prevention strategies against RSV.PMID:34449150 | DOI:10.24953/turkjped.2021.04.015 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Jefferson Antonio Buend ía Diana Guerrero Patino Denis Sinisterra Source Type: research

Timeliness of postnatal surgery in newborns with open neural tube defects: a single center experience
CONCLUSIONS: Our study appears to favor the early repair of NTD`s within the first 24 hours of life. Such an approach may reduce the risk of infectious and neurological complications significantly.PMID:34449151 | DOI:10.24953/turkjped.2021.04.016 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Ayhan Pekta ş Mehmet Gazi Boyac ı Hilal Koyuncu Mine Kanat Pekta ş Ahmet Af şin Kundak Source Type: research

Clinical and molecular characteristics of carnitineacylcarnitine translocase deficiency with c.270delC and a novel c.408C & gt;A variant
CONCLUSIONS: All three cases died despite a very intensive therapy. Based on our experience with these three cases, it can be said that CACTD has a relatively poor prognosis, molecular studies are of most importance in suspected cases for the final diagnosis and such studies might be of help while giving genetic counselling and guidance to parents for future pregnancies.PMID:34449152 | DOI:10.24953/turkjped.2021.04.017 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Berrak Bilginer G ürbüz Didem Y ücel Yılmaz R ıza Köksal Özgül Can Ko şukcu Ali Dursun Hatice Serap Sivri Turgay Co şkun Ay şegül Tokatlı Source Type: research

Outbreak of late-onset Group B Streptococcal disease with serotype Ib in a Neonatal Intensive Care Unit
CONCLUSION: Preterm delivery and VLBW are associated with an increased risk of invasive late-onset GBS infection. This report underscores the ongoing risk of nosocomial transmission of GBS in the NICU.PMID:34449153 | DOI:10.24953/turkjped.2021.04.018 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Hiroko Horie-Ota Kazushige Ikeda Source Type: research

Whole exome sequencing identifies a novel variant in ABCA3 in an individual with fatal congenital surfactant protein deficiency
CONCLUSIONS: We consider that this case report contributes to the literature on RDS by showing the presence of c.3677 T> C (p.Leu1226Pro), a new homozygous variant of ABCA3 in our patient.PMID:34449154 | DOI:10.24953/turkjped.2021.04.019 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Hayrunnisa Bekis Bozkurt Yavuz Şahin Source Type: research

A very rare cause of protein losing enteropathy: Gaucher disease
CONCLUSIONS: PLE is a devastating and life threatening complication of GD developing despite long term use of high dose ERT. Clinicians should be alert for this complication particularly in GD patients presenting with progressive abdominal distension, edema, ascites and diarrhea or in patients who have already developed mesenteric lymphadenopathies. Timely diagnosis may allow early intervention with previously suggested surgical or medical treatment options. Although there is no specific and effective treatment, surgical and aggressive medical interventions in addition to ERT were reported to relieve diarrhea and halt prog...
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Mehmet Akif G öktaş Ersin G ümüş H ülya Demir Hayriye H ızarcıoğlu Gülşen İnci Nur Saltık-Temizel Hasan Özen Şafak Güçer Aysel Y üce Source Type: research

Severe isolated sulfide oxidase deficiency with a novel mutation
CONCLUSION: The mutation identified in our patient causes severe ISOD. Early diagnosis of ISOD is essential for accurate genetic counseling and achieving prenatal diagnosis. Screening for urinary sulfite in patients with neonatal or early infantile onset seizures, developmental delay, microcephaly and cystic encephalomalacia in neuroimaging mimicking HIE helps in early diagnosis.PMID:34449156 | DOI:10.24953/turkjped.2021.04.021 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Meri ç Ergene Nuriye Yarar Elif Perihan Öncel Taner Sezer B üşranur Çavdarlı İsmail Zafer Ecevit Halil İbrahim Aydın Source Type: research

Massive true thymic hyperplasia in a 3-month-old infant: case report and literature review
CONCLUSIONS: By reviewing the literature, there were only 10 cases with MTTH reported between 1975 and 2020 for children aged
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Min Yang Lin Zeng Yi Ji Bo Xiang Zhi-Cheng Xu Source Type: research

Facial colliculus syndrome due to a Herpes simplex virus infection following Herpes labialis
CONCLUSION: Facial colliculus syndrome is rare and the treatment is based on etiology.PMID:34449158 | DOI:10.24953/turkjped.2021.04.023 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Muhittin Bodur Rabia T ütüncü Toker Abdullah Hakan Özmen Mehmet Sait Okan Source Type: research

Intranasal supernumerary tooth in a child: a case report
CONCLUSIONS: Detection of supernumerary teeth in the nasal cavity of children without symptoms is difficult, and it can be delayed; although the child, in this case, had nonspecific nasal symptoms, supernumerary teeth was not considered in the diagnosis. This case report raises awareness and provides evidence for the clinical characterization and optimal treatment of supernumerary teeth in children.PMID:34449159 | DOI:10.24953/turkjped.2021.04.024 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Yoon Seok Choi Yong-Dae Kim Chang Hoon Bae Hyung Gyun Na Source Type: research

Health insurance status and outcomes in children, adolescents, and young adults: a systematic review and meta-analysis
CONCLUSIONS: The findings of this review suggest that a lack of or insufficient insurance is related to all-cause mortality of AYAs with malignant cancers. Strategies aimed at identifying causality and reducing disparities are warranted.PMID:34449136 | DOI:10.24953/turkjped.2021.04.001 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Congyang Huang Hanshan Liu Honglian Hu Li Jia Suyun Hu Source Type: research

IgE mediated food allergy in Turkey: different spectrum, similar outcome
CONCLUSIONS: The FA spectrum of Turkish children and adolescents differs from many regions of the world with high rates of TN (hazelnut, Anacardia nuts), seed (sesame, pumpkin seed) and lentils, and low rates of soy, peanut and seafood allergies. However, resolution, emergence and persistence of allergies and comorbidities are similar, which points to the limited role of the environment in the outcome.PMID:34449137 | DOI:10.24953/turkjped.2021.04.002 (Source: The Turkish Journal of Pediatrics)
Source: The Turkish Journal of Pediatrics - August 27, 2021 Category: Pediatrics Authors: Ay şegül Akarsu Melike Ocak Gizem K öken Ümit Murat Şahiner Özge Soyer B ülent Enis Şekerel Source Type: research