Log in to search using one of your social media accounts:

 

Towards Simpler and Reliable Wound Care.
Authors: Bechstein WO PMID: 29669675 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 22, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Evaluation of Absorbent Versus Conventional Wound Dressing.
Authors: Bredow J, Hoffmann K, Oppermann J, Hellmich M, Eysel P, Zarghooni K Abstract BACKGROUND: Lower-limb endoprosthetic operations and spinal operations are among the more common types of orthopedic procedures. Postoperative woundhealing disturbances and infections can lead to longer periods of hospital stay and recovery as well as to higher morbidity and mortality. METHODS: 209 patients who had been judged to have an indication for a primary knee or hip endoprosthesis or for a primary spinal operation were included in this randomized trial (ClinicalTrials.gov: NCT01988818) over the period June 2014- Februa...
Source: Deutsches Arzteblatt International - April 22, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Insufficient Data.
Authors: Schachtner T, Spannagl M PMID: 29669677 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 22, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

In Reply.
Authors: Goldstein M PMID: 29669678 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 22, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Calcitonin Screening in Nodular Goiter-Upper Limits.
Authors: Raue F, Frank-Raue K PMID: 29669679 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 22, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

In Reply.
Authors: Bartsch DK, Luster M, Goretzki PE PMID: 29669680 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 22, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

The Diagnosis and Treatment of Functional Dyspepsia.
CONCLUSION: The impaired quality of life of patients with functional dyspepsia implies the need for definitive establishment of the diagnosis, followed by symptom-oriented treatment for the duration of the symptomatic interval. PMID: 29669681 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 22, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Skin Changes Revealing a Disorder of Lipid Metabolism.
Authors: Weins AB, Biedermann T, Brockow K PMID: 29669682 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 22, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Cardiogenic Causes of Fever.
CONCLUSION: Fever can have both infectious and non-infectious cardiac causes. Its interpretation depends on the clinical context. The evidence base for treatment is sparse, and controlled trials are needed. PMID: 29642989 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 13, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Oral Interventions for Obstructive Sleep Apnea.
Authors: Koretsi V, Eliades T, Papageorgiou SN Abstract BACKGROUND: The effectiveness of intraoral appliances (IOA), maxillary expansion (ME), and maxillomandibular advancement (MMA) in the treatment of children and adults with obstructive sleep apnea (OSA) has not yet been adequately assessed. METHODS: An umbrella review was performed based on established guidelines for evidence-based medicine. Data synthesis was performed only from randomized controlled trials with Paule-Mandel random-effects meta-analyses / meta-regressions using mean differences (MDs) and 95% confidence intervals (CIs) and was followed by t...
Source: Deutsches Arzteblatt International - April 13, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

No Panacea in Sight.
Authors: Wörz R PMID: 29642991 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 13, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

In Reply.
Authors: Lin J PMID: 29642992 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 13, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

A 21-Year-Old Man With Coronary Artery Dissection After Blunt Trauma to the Chest.
Authors: Bösche LI, Schildhauer TA, Hamsen U PMID: 29642993 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 13, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Questions upon Questions.
Authors: Certain C PMID: 29642994 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 13, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

In Reply.
Authors: Herren C PMID: 29642995 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 13, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Molecular Imaging in Oncology Using Positron Emission Tomography.
CONCLUSION: PET is an important component of diagnostic algorithms in oncology. It can help make diagnosis more precise and treatment more individualized. An increasing number of PET radiopharmaceuticals are now expanding the available options for imaging. Many radiopharmaceuticals can be used not only for noninvasive analysis of the expression of therapeutically relevant target structures, but also for the ensuing, target-directed treatment with radionuclides. PMID: 29607803 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 3, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

IgG4-Associated Inflammatory Pseudotumor with Bilobar Hepatic Foci.
Authors: Büchter M, Gerken G, Kahraman A PMID: 29607804 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 3, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Intestinal Ostomy.
CONCLUSION: Every step from the planning of a stoma to its postoperative care should be discussed with the patient in detail. Preoperative marking is essential for an optimal stoma site. Optimal patient management with the involvement of an ostomy nurse increases ostomy acceptance, reduces ostomy-related complications, and improves the quality of life of ostomy carriers. PMID: 29607805 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 3, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

The Expert's Duty of Confidentiality.
Authors: Schneider T PMID: 29607806 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 3, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Fitness to Drive After Sternotomy.
Authors: Afflerbach A PMID: 29607807 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 3, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

In Reply.
Authors: Klein HH PMID: 29607808 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 3, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Leukemia Cutis.
Authors: Dissemond J, Cesko E PMID: 29607809 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 3, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Correction of the Definition of MGUS.
Authors: Lisch W PMID: 29607810 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 3, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

In Reply.
Authors: Buske C PMID: 29607811 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 3, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Guidelines for Interpretation Required.
Authors: Schaumburg F, Becker K, Gatermann SG PMID: 29607812 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 3, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Urine Culture is the Crucial Basis.
Authors: Jantsch J PMID: 29607813 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 3, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

In Reply.
Authors: Kranz J, Schmidt S, Lebert C, Schneidewind L, Schmiemann G, Wagenlehner F PMID: 29607814 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 3, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

CUP Syndrome-Metastatic Malignancy with Unknown Primary Tumor.
Conclusion: A combination of conventional and innovative diagnostic methodsenables the provision of highly refined therapeutic strategies to patients with CUPwho are undergoing treatment in interdisciplinary cancer centers.(10):157-162 Authors: Zaun G, Schuler M, Herrmann K, Tannapfel A Abstract BACKGROUND: 2-4% of newly diagnosed cases of malignant disease involve cancer of unknown primary (CUP). This mixed entity is one of the 6 most common types of malignant disease in Germany. Highly refined treatment strategies can now be offered to patients with CUP. METHODS: This review is based on pertinent publicat...
Source: Deutsches Arzteblatt International - March 30, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Cluster-Randomized Studies.
CONCLUSION: Readers of publications on CRT should be aware of the special requirements mentioned above with respect to the design, performance, and analysis of this type of study as opposed to individually randomized studies. If no special techniques are applied in the design, performance, and analysis of a CRT, or if the assumptions underlying each of these steps have not been properly checked, then the findings of the study may well be misleading. PMID: 29587960 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - March 30, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Liquid Biopsy in Tumor Genetic Diagnosis.
CONCLUSION: Liquid biopsy and tumor tissue analysis are complementary, rather than alternative, techniques for therapeutically relevant genetic investigation of tumors. Comparative studies are needed so that further indications can be determined for liquid biopsy in the diagnostic evaluation of cancer. PMID: 29587961 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - March 30, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Opioid Rotation in Cancer Pain Treatment.
CONCLUSION: Opioid rotation can improve analgesia and patient satisfaction. The success of opioid rotation appears to depend on the magnitude of the initial dose, among other factors. Tables of equianalgesic doses should be considered no more than a rough guide for determining the dose of the new drug. Rotations to methadone should be carried out under clinical supervision in experienced hands. PMID: 29563006 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - March 24, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Angioedema Two Weeks After the Initial Administration of an ACE Inhibitor.
Authors: Bellmann B, Deppe I PMID: 29563007 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - March 24, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Considerable Heterogeneity.
Authors: Karst M, Passie T PMID: 29563008 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - March 24, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

In Reply.
Authors: Häuser W PMID: 29563009 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - March 24, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Adequate Risk Stratification.
Authors: Evangelatos N, Gerlach T PMID: 29563010 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - March 24, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

In Reply.
Authors: Kolditz M PMID: 29563011 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - March 24, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Diabetes in Childhood and Adolescence.
Authors: Ziegler R, Neu A Abstract BACKGROUND: The incidence of type 1 diabetes mellitus in childhood and adolescence is steadily rising and now stands at 22.9 new cases per year per 100 000 persons up to age 15. METHODS: This review is based on pertinent publications retrieved by a selective literature search, with special attention to the current German S3 guideline on diabetes in childhood and adolescence. RESULTS: Polydipsia, polyuria, and weight loss are the characteristic presenting symptoms of diabetes mellitus. The acutely presenting patient needs immediate stabilization because of the danger of rap...
Source: Deutsches Arzteblatt International - March 24, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Shades of Gray.
Authors: Christ M, Steuer S, von Hessling A PMID: 29563013 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - March 24, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Pulmonary Rehabilitation and Exercise Training in Chronic Obstructive Pulmonary Disease.
Authors: Gloeckl R Abstract BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a common condition that is becoming increasingly prevalent. It affects 13.2% of the population over age 40 in Germany. In 2020, it will be the third most common cause of morbidity and mortality around the world. It markedly impairs the quality of life of those who suffer from it and presents a major economic challenge to the health-care system. METHODS: This review is based on pertinent publications retrieved by a selective literature search and on the authors' clinical experience. RESULTS: Pulmonary rehabilitation (PR) ...
Source: Deutsches Arzteblatt International - March 14, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

An Exotic Visitor.
Authors: Gupta RS, Wilke K, Vieth M PMID: 29526183 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - March 14, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Chronic Heart Failure.
CONCLUSION: All patients with heart failure are suggested to be enrolled in a structured program (e.g., a disease management program) including coordinated multidisciplinary care and continuous educational interventions. In patients with a poor prognosis, more intensive care is recommended, e.g. specialized nurses, or telephone support. PMID: 29526184 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - March 14, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

The Importance of Ergometry Was Underrated.
Authors: Burgstahler C, Nieß A PMID: 29526185 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - March 14, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Current Clinical Practice Is Different.
Authors: Wollmann H PMID: 29526186 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - March 14, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

In Reply.
Authors: Albus C, Barkhausen J, Fleck E, Haasenritter J, Lindner O, Silber S PMID: 29526187 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - March 14, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Limitations of the Study.
Authors: Emeritus HA, Egidi G, Kochen MM, Popert U PMID: 29526188 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - March 14, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Incomplete and Curtailed Statements.
Authors: Mainz A PMID: 29526189 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - March 14, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

In Reply.
Authors: Beesdo-Baum K PMID: 29526190 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - March 14, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

Primary Empty Sella Syndrome and the Prevalence of Hormonal Dysregulation.
CONCLUSION: The data on PES as an incidental finding are too sparse to enable any evidence-based recommendation on the potential indications for hormone testing or its nature and extent. We advise basic neuroendocrinological testing (fasting cortisol, free thyroxine [fT4], estradiol or testosterone, insulin-like growth factor 1 [IGF-1], and prolactin). There is an unexplained discrepancy between the reported high prevalence of pituitary insufficiency among persons with PES and its low prevalence in epidemiologic studies. We suspect that the former may be high because of selection bias in the publications that we reviewed, ...
Source: Deutsches Arzteblatt International - March 8, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

The Interdisciplinary Diagnosis and Treatment of Intraocular Tumors.
CONCLUSION: Modern diagnostic and therapeutic concepts for intraocular tumors can only be implemented through the close interdisciplinary collaboration of ophthal - mologists, oncologists, radiologists, radiotherapists, pathologists, and human geneticists. PMID: 29510820 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - March 8, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

German Pregnancy Register "Rhekiss".
German Pregnancy Register "Rhekiss". Dtsch Arztebl Int. 2018 Feb 16;115(7):112 Authors: Müller-Ladner U, Fischer-Betz R PMID: 29510821 [PubMed - in process] (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - March 8, 2018 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research