Rare serotype c Haemophilus influenzae invasive isolate: characterization of the first case in Portugal

We report for the first time in Portugal a serotype cHaemophilus influenzae isolated from an adult, with HIV-1 infection. Whole-genome sequencing characterized the isolate as clonal complex ST-7, albeit with a novel MLST (ST2754) due to a uniqueatpG profile. Integration of this genome with other availableH. influenzae serotype c genomes from PubMLST revealed its overall genetic distinctiveness, with the closest related isolate being identified in France in 2020. This surveillance study, involving collaboration among hospitals and reference laboratory, successfully contributed to the identification and characterization of this rare serotype.
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research