Role of Intrapleural Urokinase in Empyema Thoracis
AbstractObjectiveTo study the role of fibrinolytic therapy in pediatric empyema in relation to duration of hospital stay, need for surgical intervention and survival to discharge.MethodsRetrospective analysis of case records of children
Source: Indian Journal of Pediatrics - October 18, 2019 Category: Pediatrics Source Type: research

Bone Marrow Failure in Children: Approach to Diagnosis and Treatment
AbstractBone marrow failure has many different etiologies, including genetic defects which manifest with specific syndromes, as well as acquired conditions as a result of insults to the bone marrow leading to aplasia. The clinical picture is varied and clues for the underlying cause may or may not be evident at the time of presentation, frequently leading to a complex workup with a battery of tests often done to rule out genetic defects. The treatment approach for bone marrow failure is very dependent on the underlying cause, which makes it all the more critical to have an accurate diagnosis. First line management essentia...
Source: Indian Journal of Pediatrics - October 18, 2019 Category: Pediatrics Source Type: research

A Human Parvovirus-Associated Arthritis: Arthrocentesis may Resolve Coxalgia
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - October 17, 2019 Category: Pediatrics Source Type: research

Henoch-Sch önlein Purpura Nephritis and Cerebral Venous Sinus Thrombosis Due to Hereditary Deficiency of Antithrombin III
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - October 17, 2019 Category: Pediatrics Source Type: research

Algoman: Gearing up for the “Net Generation” and Era of Artificial Intelligence, One Step at a Time
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - October 16, 2019 Category: Pediatrics Source Type: research

Thalassemia: Common Clinical Queries in Management
AbstractBeta thalassemia major  (TM) is the most frequent form of transfusion-dependent inherited anemia in India. The thalassemia syndromes exhibit enormous variability in their genetic basis and phenotypic expression. The authors recommend that the diagnosis of TM or non-transfusion-dependent thalassemia (NTDT) should not be based on a one-time assessment. Many patients have a chronic anemia that is not severe enough to justify regular transfusions, but the clinical course can evolve with age. Continued observation may reveal that some patients who are considered NTDT will benefit ...
Source: Indian Journal of Pediatrics - October 16, 2019 Category: Pediatrics Source Type: research

Etiological Evaluation of Global Developmental Delay
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - October 16, 2019 Category: Pediatrics Source Type: research

Fournier Gangrene in Poorly Controlled Type 1 Diabetes
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - October 16, 2019 Category: Pediatrics Source Type: research

Upper and Lower Body Segment Ratios from Birth to 18 years in Children from Western Maharashtra: Correspondence
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - October 16, 2019 Category: Pediatrics Source Type: research

Acanthosis Nigricans and Metabolic Risk Factors in Obese Children
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - October 16, 2019 Category: Pediatrics Source Type: research

Prevalence and Characteristics of Sensory Processing Abnormalities and its Correlation with FDG-PET Findings in Children with Autism
ConclusionsAll patients with severe autism had SPAs. However, they did not correlate with FDG-PET findings. (Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - October 15, 2019 Category: Pediatrics Source Type: research

Prevalence of Epilepsy and Inter-Ictal Epileptiform Discharges in Children with Autism and Attention-Deficit Hyperactivity Disorder
AbstractObjectiveTo study the prevalence of epilepsy and Inter-ictal epileptiform discharges (IED) in children with Autism spectrum disorder (ASD) and Attention-deficit hyperactivity disorder (ADHD), and the factors associated with occurrence of epilepsy in these children.MethodsChildren between 6 and 12 y attending the Child Development Centre of a tertiary-care institute in India were evaluated for ASD and ADHD as per Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5). Childhood Autism Rating Scale was used to assess ASD severity,  and Conner’s Rating Scales were used to sub-classify ch...
Source: Indian Journal of Pediatrics - September 21, 2019 Category: Pediatrics Source Type: research

Does Food Allergy Require Any Change in Measles-Mumps-Rubella Vaccination?
AbstractObjectivesTo determine the allergic reactions that develop after Measles and Measles-Mumps-Rubella (MMR) vaccination, and whether any delay in the timing of vaccination occurs in children with food allergy.MethodsChildren with food allergy who were admitted to the Şişli Hamidiye Etfal Training and Research Hospital Healthy Child Clinic between 1st January 2015 and 30th June 2018 for Measles or MMR vaccination were studied retrospectively. Their age, delayed days of vaccination, the types of allergic food, the results of the specific IgE and skin tests, and any reaction after the vaccination were recorded.ResultsD...
Source: Indian Journal of Pediatrics - September 21, 2019 Category: Pediatrics Source Type: research

Use and Safety of Gadolinium Based Contrast Agents in Pediatric MR Imaging
AbstractGadolinium-based contrast agents (GBCA) used for MR imaging are a valuable imaging resource that has benefited patient management over last three decades and largely have a high safety profile. However, recently, adverse effects related to GBCA like nephrogenic systemic fibrosis (NSF) and asymptomatic gadolinium deposition in tissues including brain are concerning. While NSF has largely stopped occurring due to precautions and guidelines to not use GBCA in patients with poor renal function, the long term effects of gadolinium deposition, especially in brain, are not known at this stage. Cautious approach needs to b...
Source: Indian Journal of Pediatrics - September 21, 2019 Category: Pediatrics Source Type: research

Peripheral Perfusion Index – Magic Wand in Prediction of Shock?
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - September 21, 2019 Category: Pediatrics Source Type: research

Autism, Epilepsy and Intellectual Disability: A Clinical Conundrum
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - September 21, 2019 Category: Pediatrics Source Type: research

Primary Immunodeficiency Disorders: Where Do We Stand?
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - September 21, 2019 Category: Pediatrics Source Type: research

Aicardi ’s Diseases of the Nervous System in Childhood: Alexis Arzimanoglou, University Hospitals of Lyon, France with Anne O’Hare, Michael V Johnston, Robert Ouvrier (eds)
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - September 21, 2019 Category: Pediatrics Source Type: research

Hemophilia – Impact of Recent Advances on Management
This article looks at current treatment models for prophylaxis and management of inhibitors, reviews the recent advances in the field (with bioengineered factor products, non-factor products and gene therapy) and summarizes the incorporation of these new interventions in the treatment plan for patients with hemophilia. (Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - September 16, 2019 Category: Pediatrics Source Type: research

Bleeding to Life: A Case Series of Hematohidrosis and Hemolacria
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - September 16, 2019 Category: Pediatrics Source Type: research

Gaucher Disease – A Rare Cause of Collodion
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - September 16, 2019 Category: Pediatrics Source Type: research

Comparison of Therapeutic Efficacy of Ferrous Ascorbate and Iron Polymaltose Complex in Iron Deficiency Anemia in Children: A Randomized Controlled Trial
ConclusionsBoth the iron salts (FA and IPC) used in the treatment of IDA showed statistically significant improvement in the hematological parameters during the 3 mo of intervention. The improvement in hematological parameters was better in FA supplemented patients as compared to IPC. (Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - September 13, 2019 Category: Pediatrics Source Type: research

Iron in Health and Disease: An Update
AbstractIron is an essential micronutrient for oxygen transport, cellular energy metabolism, and many  enzymatic reactions. Complex physiological processes have evolved for iron acquisition to meet metabolic needs while avoiding toxicity from iron-generated free radicals. Systemic iron homeostasis is centered around the regulation of iron absorption from duodenum and iron release from stores by h epcidin. Intracellular iron is maintained under tight control by iron regulatory proteins acting at post-transcriptional level. Despite these elaborate mechanisms, iron status is frequently&...
Source: Indian Journal of Pediatrics - September 13, 2019 Category: Pediatrics Source Type: research

Streptococcus pneumoniae Acquisition and Carriage
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - September 13, 2019 Category: Pediatrics Source Type: research

Kikuchi-Fujimoto Disease: An Under Recognized Cause of Fever with Lymphadenopathy
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - September 13, 2019 Category: Pediatrics Source Type: research

Sickle Cell Intrahepatic Cholestasis with Acute Liver Failure and Acute Kidney Injury: Favourable Outcome with Exchange Transfusion
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - September 13, 2019 Category: Pediatrics Source Type: research

A Novel Adverse Event of Nusinersen Treatment: Thrombocytosis
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - September 13, 2019 Category: Pediatrics Source Type: research

Correction to: Clinical Spectrum of Inherited Disorders of Metabolism
In Introduction, 4th line “In India, thereported prevalance of IEM is 1 in 2497 newborns [2] although the true pan India prevalence still remains unknown [3] ”. (Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - September 12, 2019 Category: Pediatrics Source Type: research

Inborn Errors of Metabolism in India- Where We are At!
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - September 10, 2019 Category: Pediatrics Source Type: research

Bowel Imaging in Children: Part 2
This article will cover inflammatory/infective, neoplastic and miscellaneous disorders affecting the bowel. The authors will highlight the salient imaging features for those entities. (Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - August 17, 2019 Category: Pediatrics Source Type: research

Neonatal Jaundice
AbstractHyperbilirubinemia is a common occurrence in neonates; it may be physiological or pathological. Conjugated hyperbilirubinemia may result from medical or surgical causes, and can result in irreversible liver damage if untreated. The aim of imaging is the timely diagnosis of surgical conditions like biliary atresia and choledochal cysts. Abdominal ultrasound is the first line imaging modality, and Magnetic resonance cholangiopancreatography (MRCP) also has a role, especially in pre-operative assessment of choledochal cysts (CDCs). For biliary atresia, the triangular cord sign and gallbladder abnormalities are the two...
Source: Indian Journal of Pediatrics - August 17, 2019 Category: Pediatrics Source Type: research

Vitamin D and Neurological Disorders: The Conundrum Continues
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - August 17, 2019 Category: Pediatrics Source Type: research

Is Dietary Intake Related to Test Anxiety and Scholastic Performance in Indian Adolescents? The Search Continues
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - August 17, 2019 Category: Pediatrics Source Type: research

Retraction Note to: Effect of Surfactant Therapy Using Orogastric Tube for Tracheal Catheterization in Preterm Newborns with Respiratory Distress
The Editor has retracted this article [1] because it has been previously published [2]. All authors agree to this retraction. (Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - August 17, 2019 Category: Pediatrics Source Type: research

Measles-Mumps-Rubella Vaccination in Children with Food Allergy
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - August 7, 2019 Category: Pediatrics Source Type: research

Acute Abdomen in Kawasaki Disease
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - August 7, 2019 Category: Pediatrics Source Type: research

Continuous Metabolic Syndrome Score in Children: How Useful is it?
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - August 3, 2019 Category: Pediatrics Source Type: research

Tuberculosis Control: WHO Perspective and Guidelines
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - July 12, 2019 Category: Pediatrics Source Type: research

A Novel GCH1 Mutation in An Indian Child with GTP Cyclohydrolase Deficiency
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - July 12, 2019 Category: Pediatrics Source Type: research

Juvenile Recurrent Parotitis
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - July 12, 2019 Category: Pediatrics Source Type: research

Serum Albumin and C-Reactive Protein as Predictors of Adverse Outcomes in Critically Ill Children: A Prospective Observational Pilot Study
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - July 12, 2019 Category: Pediatrics Source Type: research

Association of Fecal Microflora with Bronchiolitis
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - July 12, 2019 Category: Pediatrics Source Type: research

Notice of Duplicate Publication
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - July 12, 2019 Category: Pediatrics Source Type: research

Neutropenia in Pediatric Infections
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - July 11, 2019 Category: Pediatrics Source Type: research

Prediction of Neonatal Hyperbilirubinemia Using 1st Day Serum Bilirubin Levels: Correspondence
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - July 11, 2019 Category: Pediatrics Source Type: research

Effects of Exercise Intervention Program on Bone Mineral Accretion in Children and Adolescents with Cystic Fibrosis: A Randomized Controlled Trial
ConclusionsExercise regime was not associated with  significant improvement in BMD of CF patients, but it had a positive impact on both physical and psychological health of these patients. (Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - July 8, 2019 Category: Pediatrics Source Type: research

Isotonic v ersus Hypotonic Intravenous Maintenance Fluids in Children: A Randomized Controlled Trial
AbstractObjectiveTo compare the incidence of hyponatremia during the first 48  h in hospitalized children receiving normal salinevs. N/2 saline as maintenance intravenous fluid.MethodsThis open label, randomized controlled trial to compare the incidence of hyponatremia in hospitalized children receiving normal saline (0.9% sodium chloride in 5% dextrose)vs. N/2 saline (0.45% sodium chloride in 5% dextrose) as maintenance fluid was conducted from December 2014 through November 2015 in a tertiary care teaching hospital. Children between 1 mo and 18 y requiring maintenance intravenous fluids were randomized to receive no...
Source: Indian Journal of Pediatrics - July 6, 2019 Category: Pediatrics Source Type: research

Clinical Profile and Short Term Outcome of Children with Neutropenia
ConclusionsAcute febrile illnesses like dengue, enteric fever, malaria are the predominant causes of neutropenia. Mild neutropenia was seen in over 50% children requiring a short duration of admission (5 –8 d); without any complications. (Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - July 6, 2019 Category: Pediatrics Source Type: research

Evaluation for Vesicoureteric Reflux Following Febrile Urinary Tract Infections
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - July 6, 2019 Category: Pediatrics Source Type: research

Risk Factors of Mortality in Hospitalized Children with Severe Acute Malnutrition
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - July 6, 2019 Category: Pediatrics Source Type: research