Carbon Dioxide Fetoscopic Technique to Enhance Visualization in Cases of Placental Laser Ablation for Twin Twin Transfusion Syndrome
Dear Editor, we present a case of twin twin transfusion syndrome (TTTS) with carbon dioxide (CO2) insufflation enhancing visualization to complete fetoscopic laser ablation (FLA). 19-year-old P0 presented at 24 weeks with symptomatic stage 1 TTTS, with regular uterine contractions. Imaging revealed anterior placenta, maximum amniotic fluid (AF) vertical pockets of 12 and 1 cm in the recipient and donor sacs. Doppler studies of the umbilical artery, ductus venosus and middle cerebral arteries were normal. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 28, 2021 Category: OBGYN Authors: Roopali Donepudi, Magdalena Sanz Cortes, Ahmed Nassr, Jimmy Espinoza, Michael A Belfort, Alireza A Shamshirsaz Tags: Correspondence Source Type: research

Musculoskeletal lower back load of accoucheurs during childbirth – a pilot and feasibility study
Back problems represent one of the leading causes of accouchers ’ work-related musculoskeletal morbidities. The correct execution of birth-related maneuvers including manual perineal protection is crucial not only for the mother and child but also for obstetricians and midwives to reduce any strain on their musculoskeletal system. Therefore, the overall aim of this study was to test the feasibility of determining the effect of different accouchers’ postures (standing and kneeling) on their musculoskeletal system. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 28, 2021 Category: OBGYN Authors: Maximilian Melzner, Khaled M. Ismail, Zden ěk Rušavý, Vladimír Kališ, Franz Süß, Sebastian Dendorfer Tags: Full length article Source Type: research

Laparoscopic lateral suspension for pelvic organ prolapse: a systematic literature review
Abdominal lateral suspension with mesh represents an alternative treatment to suspend the vaginal apex. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 28, 2021 Category: OBGYN Authors: Giuseppe Campagna, Lorenzo Vacca, Giovanni Panico, Daniela Caramazza, Andrea Lombisani, Giovanni Scambia, Alfredo Ercoli Tags: Review article Source Type: research

Influence of Sports Groups on the Risk of Stress Urinary Incontinence in Sportswomen
To evaluate sports groups on the risk of stress urinary incontinence (SUI) in sportswomen and its impact on their quality of life. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 28, 2021 Category: OBGYN Authors: Michaela Selecka, Magdalena Hagovska, Alena Bukova, Jan Svihra Tags: Full length article Source Type: research

“Development and evaluation of a new Pelvic Floor muscle training Patient reported Outcome Measures (PROM) (PFMT-P)”
Pelvic floor muscles (PFMs) support the pelvic floor organs with pelvic floor dysfunction (PFD) being a common disorder, mostly related to vaginal delivery [1,2]. PFD includes different symptoms and affects the quality of life of 25% of adult women [3,4]. The literature including review articles and individual research describes how PFD symptoms can be assessed by a variety of Patient reported Outcome Measures (PROM) including urinary incontinence, pelvic organ prolapse, fecal problems, and sexual dysfunction [5 –12]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 28, 2021 Category: OBGYN Authors: M. Liebergall-Wischnitzer, T. Hopsink, S. Shimony-Kanat, N. Idilbi, A. Noble, A. Kienski Woloski Wruble Tags: Full length article Source Type: research

The effects of mode of delivery on causes of postpartum haemorrhage
Dear Editor, the occurrence of postpartum haemorrhage (PPH) and its adverse outcomes such as maternal mortality often raises concern among healthcare providers and the family members of the parturient about the appropriateness of the mode of delivery. Unfortunately, the direct association between the mode of delivery and PPH is obviously important [1] but insufficiently studied. We, therefore, reviewed the available literature to ascertain whether or not the mode of delivery predisposes and or aggravates the causes of PPH, in order to make recommendations for clinical practice. (Source: European Journal of Obstetrics, Gyne...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 27, 2021 Category: OBGYN Authors: Nnabuike Chibuoke Ngene, Jagidesa Moodley, Lameck Chinula, Mushi Matjila Tags: Short communication Source Type: research

Magnetic resonance imaging evaluation of pelvic floor structure during pregnancy
Pelvic floor disorders (PFDs) is a general term referring to diseases such as pelvic organ prolapse (POP), urinary incontinence (UI), and fecal incontinence. It is a common condition that affects a patient ’s quality of life [1]. POP, a condition involving various pelvic organs such as the bladder, uterus, vagina, intestine, and rectum descending from their original position through the vagina [2], affects more than half of women aged over 50 years [3]. The incidence of POP is expected to increase b y approximately 50% between 2010 and 2050 with progression of an aging society [4]. (Source: European Journal of Obstet...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 27, 2021 Category: OBGYN Authors: Taro Yagi, Michiko Kodama, Michiko Bun, Hiroko Shimura, Kenjiro Sawada, Masayuki Endo, Tadashi Kimura Tags: Full length article Source Type: research

Parvovirus b19 infection in pregnancy- a review
Parvovirus B19 (B19V) is a widespread infection that may affect 1-5% of pregnant women, mainly with normal pregnancy outcome. Vertical transmission occurs in 33 –51% of cases of maternal infection. B19V infection is an important cause of fetal morbidity (fetal anaemia and non-immune hydrops) and mortality, predominantly in the second trimester.Diagnosis of B19V infection requires a multi-method approach using mainly serology and PCR techniques. Severe fet al anaemia is managed with intrauterine transfusion with perinatal survival rates following intrauterine transfusion ranging from 67% to 85%. (Source: European Jour...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 27, 2021 Category: OBGYN Authors: Charles E. Gigi, Dilly O.C. Anumba Tags: Full length article Source Type: research

Which symptoms of pelvic floor dysfunction does physiotherapy improve after an OASI?
Obstetric Anal Sphincter Injury (OASI) is associated with significant morbidity in the form of pelvic floor dysfunction, both in the immediate period of healing and long term. The aim of this study was to determine the prevalence of urinary, anorectal and sexual symptoms arising from OASI within 6 weeks after delivery at their first physiotherapy appointment (immediate postnatal) and 3-6 months after delivery following completion of physiotherapy (intermediate postnatal). Symptom prevalence were compared between the two time periods and the impact of pelvic floor physiotherapy analysed to determine any changes in symptomol...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 27, 2021 Category: OBGYN Authors: Gabrielle Blades, Charlotte Simms, Holly Vickers, Victoria Kershaw, Swati Jha Tags: Full length article Source Type: research

Office Hysteroscopic Morcellation Service: Evaluation of Women Experience and Factors Affecting Satisfaction
Endometrial polyps and/or submucous fibroids (SMF) are found in up to 30% of pre- and postmenopausal women presenting with abnormal uterine bleeding [1,2]. The conventional resectoscopy is highly effective for resection; however, it requires general anesthesia (GA) in theatre and the tissue fragments have to be removed manually which adds to the operating times [3]. In the last decade, the hysteroscopic morcellation technology, utilizing an irrigation and suction system for simultaneous resection and removal of tissues, was introduced as an alternative that can be performed in the office-setting [4,5]. (Source: European Jo...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 27, 2021 Category: OBGYN Authors: Zahra Pervaiz, Sivanandana Korrapati, Ahmed Ghoubara, Ayman Ewies Tags: Full length article Source Type: research

The utility of pretreatment systemic inflammatory response biomarkers on overall survival of cervical cancer patients stratified by clinical staging
Current evidence supports the theory that inflammation plays a key role in the initiation and progression of many cancers. Systemic inflammation can influence carcinogenesis and tumor evolution, possibly by increasing the inflammatory cytokines which in turn contributes to an environment that promotes tumor development and progression [1,2]. The role of indexes based on nonspecific systemic inflammatory markers such as neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and derived neutrophil-lymphocyte ratio (dNLR) has been widely studied in different cancer types [3]. (Source: European Journal of Obstetri...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 27, 2021 Category: OBGYN Authors: Luiz Claudio Santos Thuler, B árbara Reis Wariss, Angélica Nogueira-Rodrigues, Andreia Cristina de Melo, Anke Bergmann Tags: Full length article Source Type: research

Recurrent short interpregnancy interval: maternal and neonatal outcomes
The pregnancy period is a vulnerable time for the pregnant woman and the fetus evolving in her uterus as well. Many factors are known to influence neonatal and maternal outcomes. Some of these factors are more obvious, such as preexisting medical conditions and appropriate prenatal care [1,2], while others are less obvious such as inter-pregnancy interval (IPI), also known as birth to pregnancy interval. Since the middle of the 20th century, it has been argued, and later on established scientifically, that not only direct maternal factors affect the neonatal outcome, but also indirect factors such as short or long IPI [3]....
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 27, 2021 Category: OBGYN Authors: Ari Weiss, Hen Y. Sela, Reut Rotem, Sorina Grisaru-Granovsky, Misgav Rottenstreich Tags: Full length article Source Type: research

Determination of risk factors associated with acute kidney injury during delivery or the postpartum period
By a retrospective case control study, Coles et al [1] determined the risk factors associated with acute kidney injury (AKI) during delivery or the postpartum period. As pregnancy-related AKI has been associated with increased maternal and fetal morbidity and mortality [2], their study has the potential implications. However, there are several issues in the method and results of this study on which we wish to invite the authors to comment. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 25, 2021 Category: OBGYN Authors: Yi Cheng, Tian Tian, Fu-Shan Xue, Bin Hu Tags: Correspondence Source Type: research

Promotion on labor process and relief of the low back pain by relaxing pelvic muscle with Shangliao (BL 31) point injection in women using epidural analgesia during labor: a randomized, controlled, clinical Trial
The purpose of this study was to explore the effects of combing Shangliao point injection with epidural analgesia on labor pain and birth process in women with low back pain and the possible mechanisms. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 25, 2021 Category: OBGYN Authors: Juan GU, Chao YU, Shuying LI, Juan NI, Bin LIU Tags: Full length article Source Type: research

The impact of indomethacin on the number of oocytes retrieved and IVF outcomes in patients with poor ovarian response
Poor response (POR) to controlled ovarian hyperstimulation (COH) is one of the most challenging issues in the field of reproductive medicine. Poor responders (PORs) represent a significant percentage of couples treated in IVF units (10 –24%), and POR is usually associated with a reduction in follicular response, resulting in a reduced number of retrieved oocytes, and consequently a reduction in pregnancy rates [1]. Over the last few decades, researchers have proposed a series of strategies and ovarian stimulation protocols to im prove pregnancy outcomes in patients with POR; however, clinical decisions regarding COH ...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 23, 2021 Category: OBGYN Authors: Adem Yavuz, Gokalp Oner, Mustafa Tas, Murat Sonmezer Tags: Full length article Source Type: research

Three-Dimensional Versus Two-Dimensional Laparoscopic Myomectomy: A randomized Controlled Trial
This study aimed to compare the surgical outcomes of three-dimensional (3D) and two-dimensional (2D) laparoscopic myomectomy.Study designA total of 64 patients with symptomatic uterine fibroids were randomly assigned to either the 3D (n = 32) group or the 2D group (n = 32). The primary outcomes were the operative blood loss and change in hemoglobin levels. The secondary outcome was operative time. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 23, 2021 Category: OBGYN Authors: Taejong Song, Du-young Kang Tags: Full length article Source Type: research

Evaluation Of Depression And Sleep Disorders In The Preoperative And Postoperative Period In Stage 4 Endometriosis Patients
Endometriosis is a disease that significantly affects the quality of life of patients. Continuous pelvic pain seen in patients disrupts their well-being. The aim of this study is to examine the changes in depression and sleep disorders in patients with endometriosis before and after the operation. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 23, 2021 Category: OBGYN Authors: Mustafa Goksu, Pinar Kadirogullari, Kerem Doga Seckin Tags: Full length article Source Type: research

Cytogenetic findings of ectopic endometriotic tissue in women with endometriosis and review of the literature
To determine chromosome and gene alterations in ectopic endometrial (EM) tissue which may be implicated in the clinical course or the progression of endometriosis and to review the literature concerning the cytogenetic findings of women with endometriosis. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 21, 2021 Category: OBGYN Authors: Sophia Zachaki, Marina Kalomoiraki, Elisavet Kouvidi, Emmanuel Promponas, Stefanos Syrkos, Birgit Panopoulou, Amelia Pantou, Ariadni Mavrou, Emmanuel Kanavakis, Kalliopi N. Manola Tags: Full length article Source Type: research

Pelvic floor, abdominal and uterine tenderness in relation to pressure pain sensitivity among women with endometriosis and chronic pelvic pain
Chronic pelvic pain (CPP) affects approximately 6-25% of reproductive-aged women and up to 70% of women with CPP will also have identifiable endometriosis.[1,2] While the mechanisms underlying CPP are not fully understood, it is thought that in some individuals with CPP, pain is caused (entirely or in part) due to peripheral or central nervous system (CNS) sensitization rather than as solely a direct result of endometriosis or other pelvic pathology – termed nociplastic pain by the International Association for the Study of Pain. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 21, 2021 Category: OBGYN Authors: Amy L Shafrir, Elena Martel, Stacey A. Missmer, Daniel J Clauw, Steven E Harte, Sawsan As-Sanie, Christine B Sieberg Tags: Full length article Source Type: research

Risk prediction of major haemorrhage with surgical treatment of live cesarean scar pregnancies
Caesarean scar is a relatively rare type of ectopic pregnancy which affects between 1/1800 to 2/2200 pregnancies.[1 –3] It occurs when a pregnancy implants within an incompletely healed scar of a previous caesarean section. The number of diagnosed cases can be attributed to better awareness of the condition and easier access to high frequency transvaginal ultrasound which facilitates their earlier and more accu rate detection. The incidence of caesarean scar pregnancies has also increased in the last two decades, due to the rising rates of caesarean section deliveries worldwide. (Source: European Journal of Obstetric...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 21, 2021 Category: OBGYN Authors: Lucrezia V. DE BRAUD, Jure KNEZ, Dimitrios MAVRELOS, Nikolaos THANATSIS, Eric JAUNIAUX, Davor JURKOVIC Tags: Full length article Source Type: research

Phytoestrogens: Role in urogenital atrophy, urinary disorders and sexual function
With great deal of interest we read the article entitled “Impact of phytoestrogens on treatment of urogenital menopause symptoms: A systematic review of randomized clinical trials” by Abdi et al [1]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 21, 2021 Category: OBGYN Authors: Christos Iavazzo, Ioannis D. Gkegkes Tags: Correspondence Source Type: research

Development and frozen-thawed transfer of non-pronuclear zygotes-derived embryos in IVF cycles
To explore the development and pregnancy potential of non-pronuclear (0PN) zygote-derived embryos in conventional in vitro fertilization (IVF) cycles.Study design: Embryonic development in 1039 oocyte retrieval cycles and clinical outcomes of 659 frozen-thawed blastocyst transfer cycles were retrospectively studied. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 21, 2021 Category: OBGYN Authors: Lei Fu, Wenhui Zhou, Yuan Li Tags: Full length article Source Type: research

Self-efficacy, coping strategies and quality of life in women and men requiring assisted reproductive technology treatments for anatomical or non-anatomical infertility
Worldwide around 186 million people suffer from infertility [1]. Though causes of infertility may be attributed to female, male, mixed, or unknown factors, epidemiological data show a prevalence of female-specific infertility diagnosis in one out of seven couples in the western world and in one out of four couples in developing countries [2]. At the same time, male-specific factors are found to be responsible for approximately 20 –30% of infertility cases [2–3]. Given these numbers, the demand for Assisted Reproductive Technology (ART) treatments is on the rise, as well as the need for an improvement in techniq...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 20, 2021 Category: OBGYN Authors: Federica Andrei, Paola Salvatori, Linda Cipriani, Giuseppe Damiano, Maria Dirodi, Elena Trombini, Nicolino Rossi, Eleonora Porcu Tags: Full length article Source Type: research

The prediction of morbidity related to vaginal delivery in nulliparous women - a secondary analysis from the Genesis multicenter trial
A reduction in maternal mortality has been used to measure progress in improving maternal health, although maternal mortality figures underrepresent the overall burden of maternal morbidity [1]. Maternal mortality has been described as the ‘tip of the iceberg’ and maternal morbidity as the base [1]. Demographic and anthropometric factors contribute to maternal morbidity. There is an increasing prevalence of obesity and increasing maternal age among pregnant women [2]. Gestational hypertension, chronic hypertension, pre-existing an d gestational diabetes are all more commonly associated with obesity and increasi...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 19, 2021 Category: OBGYN Authors: Khadijah I. Ismail, Naomi Burke, Gerard Burke, Fionnuala Breathnach, Fionnuala M. Mcauliffe, John J. Morrison, Michael J. Turner, Samina Dornan, John R. Higgins, Amanda Cotter, Michael Geary, Peter Mcparland, Sean Daly, Fiona Cody, Cecelia Mulcahy, Pat Di Tags: Full length article Source Type: research

Hemorrhagic hydrocele in the Canal of Nuck: A rare case of endometriosis
Endometriosis is a benign disorder that affects 10-15% of women of reproductive age [1]. Inguinal endometriosis is very rare, with a prevalence of 0.3-0.6% among women with endometriosis [2]. Hydrocele of the canal of Nuck is reported to have a prevalence of 0.74-0.76% in young girls, while cases of adult women with Nuck cyst are even more scarce [3]. Thus, endometriosis associated hydrocele of the canal of Nuck remains an extremely rare entity [4]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 16, 2021 Category: OBGYN Authors: Dimitrios Papageorgiou, Nikolaos Ivros, Vasileios Kalles, Ioannis K. Papapanagiotou, Katerina Papakonstantinou Tags: Correspondence Source Type: research

Belgian twins born with the Gamma variant of SARS-CoV-2: transplacental versus intrapartum transmission?
We would like to take this opportunity to present a 'triple' case of interest: that of a 32-year-old woman (gravida 3, para 2) admitted to a tertiary hospital in Brussels, Belgium, and her twins (bi-chorionic bi-amniotic). She had no relevant past medical history except for gestational diabetes treated with diet alone, when she presented at 30 weeks and 5 days' gestation with preterm prelabor rupture of membranes. The 27-week ultrasonography had showed growth at the 44th and 25th percentile and normal doppler signals. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 16, 2021 Category: OBGYN Authors: Hanne Massa, Lucie Seyler, Louise Cras, Thomas Demuyser Tags: Correspondence Source Type: research

The role of suprapubic catheter insertion in preventing urinary tract infections following intravesical Botulinum toxin A
Intravesical botulinum toxin A (BTX-A) is recommended for the management of refractory detrusor overactivity [1]. Recognised side effects include increased urinary tract infections (UTIs) rates and voiding dysfunction, which may be related. Management of voiding dysfunction may require catheterisation [2]. While use of clean intermittent self-catheterisation (CISC) after BTX-A is well reported in the literature [2], we are not aware of any evidence detailing use of suprapubic catheter (SPC) concomitant or following intravesical BTX-A. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 16, 2021 Category: OBGYN Authors: Adeolu Banjoko, Tom Fawcett, Martino Zacche, Philip Toozs-Hobson Tags: Correspondence Source Type: research

Pre treatment and post treatment Positron Emission Tomography –Computed Tomography (PET–CT) to evaluate treatment response in Tuberculous Tubo-Ovarian Masses
Female genital Tuberculosis (FGTB) causes infertility and formation of Tubo-ovarian (TO) masses. The study showed treatment response of PET-CT in evaluation of anti-tubercular treatment response in patients of infertility with tuberculous TO masses. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 15, 2021 Category: OBGYN Authors: J.B. Sharma, Rakesh Kumar, Urvashi Singh, Anukriti Kumari, Sona Dharmendra, Hemant Sachani Tags: Full length article Source Type: research

Seminal plasma metabolomics profiles following long (4-7 days) and short (2 hours) sexual abstinence periods
Metabolomic profiling of seminal plasma has been suggested as a possible approach for a fast and non-invasive male infertility evaluation diagnosis. However, metabolomics profiles in normozoospermic men have not been thoroughly investigated, and the influence of ejaculation-abstinence has not been described.To provide interim reference values and find associations between the metabolomics profiles of human seminal plasma and length of ejaculation-abstinence period in normozoospermic men. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 14, 2021 Category: OBGYN Authors: H. Alipour, R.K. Duus, R. Wimmer, F. Dardmeh, S.S. Du Plessis, N. J ørgensen, O.B. Christiansen, C. Hnida, H.I. Nielsen, G. Van Der Horst Tags: Full length article Source Type: research

Operative hysteroscopy in the minimally invasive management of interstitial pregnancy and interstitially retained products of conception: a case report and systematic literature review
An interstitial ectopic pregnancy is defined as a gestation where implantation occurs in the intramural part of the fallopian tube, surrounded by myometrium. They comprise 2 – 4% of all tubal pregnancies [1–4]. Even though the terms are often used interchangeably, it is important to distinguish an interstitial pregnancy from a cornual and an angular pregnancy [1,2]. The term cornual pregnancy refers to a pregnancy in a rudimentary horn or within one horn of a septat e or uni- or bicornuate uterus. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 14, 2021 Category: OBGYN Authors: D'hoore Eva, D'hoore Laura, Van den Berghe Sarah, Roets Ellen, van Wessel Steffi, Hamerlynck Tjalina Tags: Review article Source Type: research

Gestational Trophoblastic Neoplasia: A Unique Challenge in Caesarean Scar Pregnancy
To, (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 13, 2021 Category: OBGYN Authors: Sanjaykumar G. Tambe, Khushboo Goel, Kavita Sambharam Tags: Correspondence Source Type: research

Preoperative leukocytosis correlates with unfavorable pathological and survival outcomes in endometrial carcinoma: a systematic review and meta-analysis
To meta-analytically examine the frequency and prognostic impact of preoperative leukocytosis in endometrial carcinoma (EC). (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 13, 2021 Category: OBGYN Authors: Ahmed Abu-Zaid, Osama Alomar, Saeed Baradwan, Mohammed Abuzaid, Majed Saeed Alshahrani, Hassan Saleh Allam, Saad Mohammed S. Alqarni, Ahmed Nazer, Hany Salem, Ismail Abdulrahman Al-Badawi Tags: Review article Source Type: research

Has the prevalence of levator avulsion after forceps delivery changed over the last six decades? A retrospective study in a urogynaecological population
Forceps delivery is associated with a higher risk of maternal birth trauma. It is speculated that it is due to sub-optimal use of forceps in inexperienced hands. The aim of this study was to determine the association between time of forceps birth and prevalence of levator avulsion over the last six decades. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 13, 2021 Category: OBGYN Authors: S. Arcanjo Lino, K.L. SHEK, J. Caudwell-Hall, M. GILLOR, H.P. Dietz Tags: Full length article Source Type: research

Hypothyroidism and urinary incontinence: prevalence and association in a Danish, female sample from the Lolland-Falster Health Study
Hypothyroidism is more prevalent in women and older people (>65 years).[1] The reported prevalence in women ranges from 0.2% to 5.3%[2 –6], and the prevalence of subclinical hypothyroidism (SHT) is up to 10% in iodine-sufficient populations.[3,4] Hypothyroidism affects multiple organ systems implying a variety of symptoms. Thyroid-stimulating hormone (TSH) is shown to affect striated and smooth muscles, blood vessels, fibroblasts in bones, and the glomerular filtration.[7,8] Our knowledge on how TSH and hypothyroidism affect the lower urogenital tract in detail is sparse and divergent. (Source: European Journal of...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 13, 2021 Category: OBGYN Authors: Ea L øwenstein, Randi Jepsen, Lea Laird Andersen, Jennie Laigaard, Lars Alling Møller, Peter Gæde, Lisbeth Bonde, Helga Gimbel Tags: Full length article Source Type: research

Expectant management versus multifetal pregnancy reduction in Dichorionic Triamniotic (DCTA) triplets: single centre experience
This study investigates if the method of reduction used in DCTA triplet pregnancy influences the evidence of benefit from MFPR. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 13, 2021 Category: OBGYN Authors: C.J. Shaw, G. Paramasivam, C. Vacca, C.C. Lees Tags: Full length article Source Type: research

Changes of Pelvic Organ Prolapse and Pelvic Floor Dysfunction Throughout Pregnancy in Singleton Primigravidas: A Prospective Cohort Study
Pelvic floor support is a highly dynamic structure, which is kept in balance by pelvic floor muscles, endopelvic fascia, connective tissue and pelvic bones. Any changes in these factors may cause an unpredictable imbalance in the pelvic floor, which emerges as pelvic floor disorders (PFDs) including pelvic organ prolapse (POP), voiding and defecatory dysfunction, and sexual dysfunction. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 13, 2021 Category: OBGYN Authors: Elif Nazl ı Çetindağ, Fulya Dökmeci, Şerife Esra Çetinkaya, Mehmet Murat Seval Tags: Full length article Source Type: research

YouTube as a source of information on gonadotropin self-injections
Infertility is a frequently encountered health problem with severe psychological, economic, and social aspects [1,2]. Its incidence is estimated to be in the range of 12-18%. Currently, one of the treatment options for infertility is the use of gonadotropins; there are preparations including follicle-stimulating hormone (FSH) or luteinizing hormone (LH) or a combination of both. Proper use of these costly medications and patient compliance are crucial in the success of treatments such as ovulation induction and controlled ovarian hyperstimulation. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 12, 2021 Category: OBGYN Authors: Feyza Nur İncesu Çintesun, Ersin Çintesun, Özlem Seçilmiş Tags: Full length article Source Type: research

Pregnant women ́s views on the timing of prophylactic antibiotics during caesarean delivery: a qualitative semi-structured interview study
Whether prophylactic antibiotics should be administered before or after cord clamping at caesarean section have been discussed. Today most obstetric societies recommend administration 30-60 minutes before the caesarean section [1]. However, currently no studies are available concerning pregnant women ’s attitudes toward these recommendations. As intravenous antibiotics given before the caesarean section exposes the fetus to antibiotics via placental transfer and remain in the infant up to 24 hours postpartum, the practice is not without some potential risks to the infant. (Source: European Journal of Obstetrics, Gyne...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 9, 2021 Category: OBGYN Authors: Sidsel H øgh-Poulsen, Jane M. Bendix, Maria Mieskiewicz Larsen, Rie Adser Virkus, Anne Dsane Andersen, Tine Dalsgaard Clausen, Ellen Christine Leth Løkkegaard, Paul Bryde Axelsson Tags: Full length article Source Type: research

Serous Endometrial Intraepithelial Carcinoma: A Clinico-Pathological study of 48 cases and its association with Endometrial Polyps – A Tertiary Care Oncology Centre Experience
Endometrial serous carcinoma (ESC) is an aggressive neoplasm wherein the recent studies have shown that it arises from its putative precursor namely the serous endometrial intraepithelial carcinoma (SEIC). SEIC usually arises in inactive/ atrophic endometrium but surprisingly is frequently associated endometrial polyps (EPs). The aim of this study was to assess the incidence of SEIC with or without invasion, its clinical behaviour and association with endometrial polyp. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 8, 2021 Category: OBGYN Authors: C. Yadav Subhash, Agarwal Arti, Mokal Smruti, Menon Santosh, Rekhi Bharat, Deodhar Kedar Tags: Full length article Source Type: research

Zika virus infection in pregnant women and their children: A review
Zika virus (ZIKV) is an RNA arthropod-borne virus (arbovirus) from the Flavivirus genus and the Flaviviridae family [1,2]. Other viruses of clinical importance in the family are Dengue virus (DENV), West Nile virus (WNV) and Yellow Fever virus (YFV) [2]. In 1947, scientists conducting routine surveillance for YFV in the Zika forest in Uganda first isolated the ZIKV in samples taken from a captive, sentinel rhesus monkey [1]. Antibodies anti-ZIKV were detected in serosurvey studies in different animals which could act as their hosts, that included monkey species in Africa and Asia, bats, goats, rodents, and sheep [1]. (Sour...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 8, 2021 Category: OBGYN Authors: Elena Marb án-Castro, Anna Goncé, Victoria Fumadó, Lucía Romero-Acevedo, Azucena Bardají Source Type: research

Levofloxacin or gonadotropin releasing hormone agonist treatment decreases intrauterine microbial colonization in human endometriosis
Endometriosis is an estrogen-dependent chronic inflammatory condition mostly affecting women of reproductive age and is associated with chronic pelvic pain and infertility. Even after long three hundred years, most of the literatures [1 –3] still claim that pathogenesis and/or pathophysiology of endometriosis is unclear. We came to learn so far some established hypothesis and regulatory factors supporting the development and maintenance of endometriosis [1,3]. Recently it has been demonstrated that besides hormonal regulation, bo th initial and secondary inflammatory mediators are known to be involved in the growth o...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 8, 2021 Category: OBGYN Authors: Khaleque N Khan, Akira Fujishita, Hideki Muto, Hiroshi Masumoto, Kanae Ogawa, Akemi Koshiba, Taisuke Mori, Kyoko Itoh, Satoshi Teramukai, Katsuya Matsuda, Masahiro Nakashima, Jo Kitawaki Tags: Full length article Source Type: research

Evaluation of frozen section biopsy for fast track diagnosis of endometrial pathology in high-risk women with abnormal uterine bleeding
Abnormal uterine bleeding is usually a symptom of benign conditions; however, it is also the most common symptom of endometrial hyperplasia or cancer therefore warrants early workup and need for specialist investigation[1,2]. Endometrial cancer is the sixth most common cancer in women worldwide, with 417,367 new cases diagnosed in 2020[3]. Endometrial cancer most commonly presents with postmenopausal bleeding, depending on age and risk factors 10-15% of such women will have endometrial cancer and also as a perimenopausal abnormal uterine bleeding (AUB)[4,5]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 7, 2021 Category: OBGYN Authors: Arnika Kashyap, Shalini Rajaram, Bindiya Gupta, Vinod Kumar Arora, Lalendra Upreti, Sandhya Jain Tags: Full length article Source Type: research

Uterine rupture: results from a prospective population-based study in Italy
Uterine rupture (UR) is an obstetric complication occurring during pregnancy or delivery in less than 1 per 1000 pregnancies in Western countries [1 –4]. Although rare, it represents a potentially life-threatening event as it may result in emergency hysterectomy and/or severe morbidity and complications for the mother and fetus. Uterine scarring increases the risk of UR, especially if vaginal birth after caesarean section (VBAC) is attempted [ 2,5,6]. In fact, a uterine scar due to a previous caesarean section (CS) or other uterine surgery increases the estimated incidence of UR to 1–8 per 1000 women [3,5]. (So...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 6, 2021 Category: OBGYN Authors: Serena Donati, Valeria Fano, Alice Maraschini, Regional Obstetric Surveillance System Working Group Tags: Full length article Source Type: research

Catastrophic antiphospholipid syndrome during pregnancy
Catastrophic antiphospholipid syndrome (CAPS) is an uncommon and the most severe form of antiphospholipid syndrome (APS). A 33-week pregnant patient with Klippel-Trenaunay syndrome, past SARS-CoV-2 infection and type I fetal growth restriction with shortening of the fetal long bone was diagnosed in our center with a probable CAPS. Cesarean section was performed four days after the diagnosis due to the torpid evolution of the patient. Clinical improvement was noted a few days later and the mother and baby were discharged within a week. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 6, 2021 Category: OBGYN Authors: Marta Fuentes Carrasco, Alejandra Mayoral Triana, Ignacio Crist óbal García, Noelia Pérez Pérez, Nuria Izquierdo Méndez, Patricia Soler Ruiz, Virginia González González Tags: Review article Source Type: research

Evaluation of Fetal Cardiac functions in the setting of Maternal Diabetes: Application of the Global Spherical Index, Global Strain and Fractional Area Change by the Speckle Tracking Technique
To evaluate ventricular contractility and profile heart deformations in fetuses of hyperglycemic mothers using the Speckle tracking imaging (STI). The fractional area change (FAC), global longitudinal strain (GLS) and global sphericity index (GSI) of the 4-chamber view (4-CV) were computed. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 6, 2021 Category: OBGYN Authors: Yan Song, Hong Yin, Wen Wang, Yu-fen Zou, De-quan Liu, Ge Zhang, Xiao-ping Ji Tags: Full length article Source Type: research

No effect of calcium and vitamin D intake on maternal blood pressure in a healthy pregnant population
Pregnancy causes physiological changes in blood pressure (BP). In patients without pre-existing hypertension, BP falls during the first half of pregnancy and rises from 34 weeks onwards [1]. Hypertensive disorders in pregnancy (HDP) complicate approximately 10% of pregnancies and are associated with adverse outcomes for both mother and foetus [2]. Women with a history of HDP are also at increased risk of developing hypertension in later life as well as ischaemic heart disease, stroke and renal disease [3]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 6, 2021 Category: OBGYN Authors: Hannah Forde, Rachel K. Crowley, Malachi J. McKenna, Mark T. Kilbane, Marie Conway, Ciara M. McDonnell, Patrick J. Twomey, Fionnuala M. McAuliffe Tags: Full length article Source Type: research

Maternal and neonatal outcomes in women undergoing Roux-en-Y gastric bypass: a systematic review and meta-analysis
To summarize evidence of benefits and risks of maternal and neonatal outcomes among pregnant women after Roux-en-Y gastric bypass surgery. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 6, 2021 Category: OBGYN Authors: Siyu Yang, Leshan Zhou, Yijing Chen, Daniel Krewski, Shi Wu Wen, Ri-hua Xie Tags: Review article Source Type: research

Association of ABO and Rh Blood Groups with obstetric outcomes in SARS-CoV-2 infected pregnancies: A prospective study with a multivariate analysis
To evaluate the influence of ABO and Rh blood groups on morbidity among SARS-CoV-2 infected pregnancies. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 6, 2021 Category: OBGYN Authors: Jos é Antonio Sainz Bueno, Lucas Cerrillos González, Alejandra Abascal-Saiz, María Victoria Rodríguez Gallego, Rocío López Pérez, Ana María Fernández Alonso, Maria Luisa de la Cruz Conty, Rubén Alonso Saiz, Magdalena Molina Oller, Amparo Cruz-Sa Tags: Full length article Source Type: research

Prenatal diagnosis of isolated clubfoot: diagnostic accuracy and long-term postnatal outcomes
Congenital talipes equinovarus (cTEV), also known as clubfoot, is a congenital musculoskeletal deformity with a prevalence of 1-3/1000 livebirths, characterized by the presence of plantar flexion (equinus), inward rotation of the heel (varus) and supination and adduction of the forefoot [1]. Clubfoot is classified into complex and isolated: the complex form affects approximately 25% of patients and it is associated with other congenital or functional anomalies, chromosomal abnormalities or genetic syndromes [2]; the isolated type is considered an isolated anomaly of the lower limbs. (Source: European Journal of Obstetrics,...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 6, 2021 Category: OBGYN Authors: Ilaria Fantasia, Daniela Dibello, Valentina Di Carlo, Giulia Colin, Moira Barbieri, Chiara Belcaro, Elena Magni, Flavio Faletra, Travan Laura, Tamara Stampalija Tags: Full length article Source Type: research

Consent on the labour ward: a qualitative study of the views and experiences of healthcare professionals
Consent on the labour ward is a complex and controversial topic which is poorly understood. Consenting labouring women is recognised as challenging and problematic, and thus, it is uncertain that pregnant women experience true informed consent during labour. This project aims to explore healthcare professionals ’ views and experiences of consent practice on the labour ward.Design:Qualitative research performed in a tertiary hospital labour ward in Central London with 5,500 patients annually. Eleven obstetricians and seven midwives participated. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - July 6, 2021 Category: OBGYN Authors: Sophie Kennedy, Anne Lanceley, Melissa Whitten, Clodagh Kelly, Jacqueline Nicholls Tags: Full length article Source Type: research