Association between obesity with pattern and length of menstrual cycle: The role of metabolic and hormonal markers
Obesity is a problem of public health, whose prevalence increases worldwide [1]. Women with obesity have increased risk of irregular menstrual cycle length [2], which can lead to an increased risk of miscarriage and fertility problems [3]. There are some established mechanisms whereby obesity could affect the follicular phase (FP) and luteal phase (LP) of the menstrual cycle. First is due to hyperinsulinemia, which generates an imbalance in SHBG and androgens, avoiding adequate ovulation [2,4]. Second, obesity produces chronic metabolic and systemic inflammation, altering the reproductive functions of the hypothalamic &nda...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 24, 2021 Category: OBGYN Authors: Alejandra Andrea Roman Lay, Ana Pereira, Maria Luisa Garmendia Miguel Tags: Full length article Source Type: research

In vitro fertilization outcomes in women with polycystic ovary syndrome: A meta-analysis
During the past three decades, applying IVF for infertility treatment PCOS women has increased significantly, and the landscape of treatment strategies has changed dramatically. However, early review of IVF on PCOS have insufficiently accounted for efficacy and safety of the technic. With abundant studies in recent years, there is a need to reconcile these new data. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 24, 2021 Category: OBGYN Authors: Kefu Tang, Lei Wu, Ying Luo, Bo Gong Tags: Full length article Source Type: research

Further evidence that endometriosis is related to tubal and ovarian cancers: a study of 271,444 inpatient women
Endometriosis is defined as the presence of endometrial glands and/or stroma outside the uterine cavity. It is estimated that approximately 10% of premenopausal women have endometriosis [1]. In symptomatic women with pelvic pain or infertility, the prevalence of endometriosis is between 35% and 50% [2,3]. As some women with endometriosis are asymptomatic, the exact prevalence is unknown. The pathogenesis of endometriosis remains unclear; some authors believe that endometriotic cells originate from the uterus, while others have implicated other tissues including stem cells [4,5]. (Source: European Journal of Obstetrics, Gyn...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 23, 2021 Category: OBGYN Authors: Perrine Capmas, Eva Suarthana, Togas Tulandi Tags: Full length article Source Type: research

Same-Day Discharge After Minimal Invasive Hysterectomy: Applications for Improved Value of Care
(Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 23, 2021 Category: OBGYN Authors: Meiyuzhen Qi, Samia Lopa, Shalkar Adambekov, John A. Harris, Suketu Mansuria, Robert P. Edwards, Faina Linkov Tags: Full length article Source Type: research

Does the choice of pelvic organ prolapse treatment influence subjective pelvic-floor related quality of life?
The relationship between pelvic organ prolapse (POP) treatment and subjective pelvic-floor related quality of life (QoL) was examined. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 23, 2021 Category: OBGYN Authors: Greta L. Carlin, Raffaela Morgenbesser, Oliver Kimberger, Wolfgang Umek, Klaus Bodner, Barbara Bodner-Adler Tags: Full length article Source Type: research

Formal institutional guidelines promotes the vaginal approach to hysterectomy in patients with benign disease and non-prolapsed uterus
Globally, hysterectomy serves as the most common treatment for benign uterine conditions [1,2]. Hysterectomy can be performed via the abdominal, vaginal, or laparoscopic route, with or without robotic assistance. The advantages provided by both vaginal and laparoscopic hysterectomy (VH and LH, respectively) over abdominal hysterectomy (AH) include less postoperative pain and need of analgesia, shorter hospital stay, more rapid recovery and return to daily activities, and reduced hospital charges and therefore cost [3 –7]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 22, 2021 Category: OBGYN Authors: Andreas Chrysostomou, Dusan Djokovic, Elena Libhaber, William Edridge, Bruno J. van Herendael Tags: Full length article Source Type: research

Tuberculosis (tb) in pregnancy – a review
Tuberculosis (TB) is a common infectious pathology especially in low-income countries, which may complicate pregnancy. Although pulmonary TB is more common in pregnancy than extra pulmonary TB (EPTB), EPTB is becoming more common especially in those living with human deficiency virus (HIV) co infection or have other comorbidities. The diagnosis of TB may be delayed in pregnancy due to the masking of its symptoms by those of pregnancy. If diagnosed and treated on time both pulmonary TB and EPTB are associated with excellent maternal and perinatal outcome. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 19, 2021 Category: OBGYN Authors: Ngozi Orazulike, J.B. Sharma, Sangeeta Sharma, Odidika U.J. Umeora Tags: Review article Source Type: research

The association between psychosocial interventions and fertility treatment outcome: a systematic review and meta-analysis
Does psychosocial intervention affect pregnancy outcomes in women and couples undergoing assisted reproductive technology (ART) treatment? (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 18, 2021 Category: OBGYN Authors: Nitasha Katyal, Cecilie M üller Poulsen, Ulla Breth Knudsen, Yoon Frederiksen Tags: Review article Source Type: research

Efficacy of myoinositol in treatment of gestational diabetes mellitus in Asian Indian women: A pilot randomized clinical trial
Gestational diabetes mellitus (GDM) is glucose intolerance diagnosed during pregnancy that is not clearly overt diabetes [1]. The International Diabetes Federation estimated globally 15.8% of women with live births in 2019 had hyperglycemia in pregnancy; of which 83.6% were due to GDM [2]. GDM is associated with increased maternal and perinatal morbidity and also the long-term consequences, includingtype-2 diabetes and cardiovascular complications in mothers, and obesity and adult onset diabetes in children born to these mothers [3]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 18, 2021 Category: OBGYN Authors: Vidushi Kulshrestha, Shrey Balani, Garima Kachhawa, P. Vanamail, Rajesh Kumari, J.B. Sharma, Neerja Bhatla Tags: Full length article Source Type: research

Prevalence Threshold of Screening Tests in Obstetrics and Gynecology
To compare various screening tests used in obstetrics and gynecology based upon their prevalence thresholds. We define the prevalence threshold as the prevalence level below which a test ’s positive predictive value (PPV) declines most sharply relative to disease prevalence – and thus the rate of false positive results/false discovery rate increases most rapidly. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 18, 2021 Category: OBGYN Authors: Liora Elfassy, Ariane Lasry, Yaron Gil, Jacques Balayla Source Type: research

Retroperitoneal ectopic pregnancy: a literature review of reported cases
To provide reference for the diagnosis and treatment of retroperitoneal ectopic pregnancy (REP), we conducted a review on all of the reported cases in English by summarizing their clinical manifestation, diagnosis, management and prognosis. A total of 25 literatures including 26 REP cases were collected from PubMed database. 40% (10/25) of the patients had a history of tubal pregnancy, 65.4% (17/26) was spontaneous pregnancy, and the average period of amenorrhea was 56.7 days. Abdominal pain is the most common (53.8%, 14/26) symptom of REP. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 17, 2021 Category: OBGYN Authors: Zhenbo OuYang, Shiyuan Wei, Jiawen Wu, Zixian Wan, Min Zhang, Biting Zhong Source Type: research

A Fetal Reduction from Twin to Singleton Based on Sonography and Cell-free Fetal DNA Testing: A Sequential Approach to Old Pitfalls
We examined the potential value of combining ultrasound and non-invasive prenatal screening (NIPS) of maternal blood to screen for major aneuploidies as an early approach before selective fetal reduction from twin pregnancy to singleton. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 17, 2021 Category: OBGYN Authors: Yaakov Melcer, Ran Svirsky, Shira Dvash, Marina Pekar-Zlotin, Hamutal Meiri, Ron Maymon Tags: Full length article Source Type: research

Maternal serum alpha-fetoprotein level and the relationship to ventriculomegaly in fetal neural tube defect: a retrospective cohort study
To estimate the significance of the association between mid-trimester maternal serum alpha-fetoprotein (MSAFP) level and fetal neuroanatomic findings in cases of open neural tube defect (ONTD). (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 16, 2021 Category: OBGYN Authors: Romain Corroenne, Katherine Zhu, Gunes Orman, Thierry A.G.M. Huisman, Amy R. Mehollin-Ray, Emily Johnson, Rebecca M. Johnson, Aline Andrucioli, Jimmy Espinoza, Ahmed A. Nassr, Michael Belfort, Roopali Donepudi, Alireza A. Shamshirsaz, Kjersti Aagaard, Wil Source Type: research

Weaponizing HIV: qualitative interviews with pregnant Zambian women depicting a unique typology of HIV-specific intimate partner violence
The bidirectional relationship between HIV and intimate partner violence (IPV) among women has been well established in the literature where is IPV is a risk factor for HIV and women living with HIV (WLWH) are at increased risk of IPV [1 –4]. Further, IPV is associated with sub-optimal engagement in HIV care and treatment adherence among WLWH. In Zambia, a southern African country with the seventh highest HIV prevalence globally, 14% of adult women are living with HIV and 47% of women report IPV [2,5]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 15, 2021 Category: OBGYN Authors: Margo S. Harrison, Marcella Fasano, Sharon Nkwemu, Karen Hampanda Tags: Short communication Source Type: research

Evaluation of the efficacy of vaginal progesterone in preventing preterm birth after abdominal trachelectomy
Abdominal trachelectomy (AT) has been used as a fertility-sparing surgery for early-stage cervical cancer in women of reproductive age since the first report (Smith JR, 1997) on the same was published [1], and is defined as surgical removal of the uterine cervix with preservation of the uterine body. The incidence of cervical cancer in reproductive-aged women is increasing [2 –4], and the number of women desiring pregnancy after AT is also increasing accordingly. Many reports on obstetric outcomes in pregnant women after AT in the past have described the high risk of miscarriage, preterm birth, and preterm premature ...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 13, 2021 Category: OBGYN Authors: Yuka Sato, Nobuhiro Hidaka, Atsuhiko Sakai, Saki Kido, Yasuyuki Fujita, Kaoru Okugawa, Hideaki Yahata, Kiyoko Kato Tags: Full length article Source Type: research

Vaginal prostaglandin E2 versus double-balloon catheter for induction of labour for vaginal birth after caesarean section: A Retrospective Cohort Study
To compare the success of the double-balloon catheter (DBC) versus prostaglandin gel (PGE2) for induction of labour in women with one previous caesarean section. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 11, 2021 Category: OBGYN Authors: Si ân Bullough, Jessica Southward, Andrew Sharp Tags: Full length article Source Type: research

Pustular psoriasis of pregnancy managed with labor induction
We are pleased to communicate a case of a 44-year-old pregnant woman who was admitted to the emergency department, at 37 weeks of gestation, after a 5-day history of an itchy maculopapular rash. The patient had no personal medical history. As for her family history, her father and an aunt on her father ’s side had a history of psoriasis. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 10, 2021 Category: OBGYN Authors: Laura Alonso-Naranjo, Álvaro González-Cantero Tags: Short communication Source Type: research

KH domain containing 3 like (KHDC3L) frame-shift mutation causes both recurrent pregnancy loss and hydatidiform mole
Recurrent pregnancy loss (RPL) is a common infertility-related complication that affects approximately 1-3% of women worldwide. Known causes of etiology are found in approximately half the cases but the other half remain unexplained. It is estimated that several thousands of genes contribute to reproductive success in mammals and the genetic causes of RPL cannot be fully addressed through targeted genetic tests. In recent years, massive parallel sequencing technologies has helped discovering many causal mutations in hereditary diseases such as RPL. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 10, 2021 Category: OBGYN Authors: Nayeralsadat Fatemi, Pierre F. Ray, Fariba Ramezanali, Tina Shahani, Amir Amiri-Yekta, Zine-Eddine Kherraf, Caroline Cazin, Navid Almadani, Maryam Varkiani, Soheila Sarmadi, Niloofar Sodeifi, Hamid Gourabi, Alireza Biglari, Mehdi Totonchi Tags: Full length article Source Type: research

An unusual complication following Sacrospinous Fixation for Vaginal Vault Prolapse
A 74-years-old woman presented with recurrent apical prolapse (POPQ stage 3). Previous surgical history includes abdominal hysterectomy for menorrhagia and posterior repair with sacrospinous fixation (SSF) for vault prolapse. She was unsuitable for a mesh-based abdominal sacrocolpopexy due to fibromyalgia and chronic pain syndrome, and underwent vaginal repair with SSF. Dissection during surgery was difficult due to scarring. On 1  st postoperative day, she had a syncopal episode. Blood results revealed a significant drop in her haemoglobin (120 g/L to 88 g/L) and hyponatremia (123 mmol/L) that ...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 9, 2021 Category: OBGYN Authors: Vandna Verma, Kristina Savickaite, Smita Rajshekhar, Ashish Pradhan Tags: Short communication Source Type: research

Needlestick injuries among Obstetrics and Gynecology trainees: a survey study
To assess characteristics, incidence, risk factors, and reporting rate of needlestick injuries (NSIs) among Obstetrics and Gynecology trainees. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 9, 2021 Category: OBGYN Authors: Massimo Franchi, Simone Garzon, Antonio Simone Lagan à, Silvia Baggio, Antonella Cromi, Fabio Ghezzi, Giovanni Scambia, Ricciarda Raffaelli Tags: Full length article Source Type: research

Effects of fetal involvement of inadvertent radioactive iodine therapy for the treatment of thyroid diseases during an unsuspected pregnancy
Radioactive iodine (131I) therapy is absolutely contraindicated in pregnancy, but reports of inadvertent exposure continue to appear in the literature. Radiation-induced effects on the embryo/fetus are highly dependent on the stage of pregnancy, the dose absorbed by the embryo/fetus, and the manifestations of the pathological condition that develops as a result of the irradiation. Prior to implantation, the major concern is death of the embryo when exposed to radiation greater than the 100  mGy threshold. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 6, 2021 Category: OBGYN Authors: Shigeo Iijima Tags: Review article Source Type: research

What We Know about Placenta Accreta Spectrum (PAS)
Placenta accreta spectrum (PAS) is an umbrella term for a variety of pregnancy complications due to abnormal placental implantation, including placenta accreta, placenta increta and placenta percreta. During the past several decades, the prevalence of PAS has been increasing, and the clinical importance of this disease is significant because of the severe complications. In this review, we summarized the available evidence-based data for PAS in various aspects: prevalence, risk factors, pathogenesis, clinical presentation and prenatal screening, and clinical management. (Source: European Journal of Obstetrics, Gynecology, a...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 6, 2021 Category: OBGYN Authors: Xiyao Liu, Yu Wang, Yue Wu, Jing Zeng, Xi Yuan, Chao Tong, Hongbo Qi Tags: Review article Source Type: research

Optimal timing of cervical cerclage removal following preterm premature rupture of membranes; a retrospective analysis
Preterm birth, defined as delivery before 37 weeks ’ gestation, is a major cause of neonatal morbidity and mortality; with up to a third of all neonatal deaths occurring as a direct result of prematurity [1]. Preterm infants who survive past early childhood have higher rates of long-term health complications, including neurological, respiratory an d developmental disabilities [2]. Current preventative management of women at high risk of preterm delivery includes the use of a cervical cerclage to provide mechanical support to the cervix and its mucus plug during pregnancy. (Source: European Journal of Obstetrics, Gyne...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 6, 2021 Category: OBGYN Authors: Natalie Suff, Maria Kunitsyna, Andrew Shennan, Manju Chandiramani Tags: Full length article Source Type: research

Herpes simplex virus infection in pregnancy – an update
Herpes Simplex virus (HSV) infection is one of the most common sexually transmitted infections among women of the reproductive age. It is estimated to affect about 2-3% of pregnant women. Vertical transmission during pregnancy is rare occurring in less than 1% of cases but for those with active lesions or shedding the virus asymptomatically the risk of vertical transmission intrapartum is high. Neonates with HSV may develop severe consequences such as disseminated, central nervous system and skin, eye mouth/mucous disease or suffer mortality. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 4, 2021 Category: OBGYN Authors: Wafaa Belail Hammad, Justin C. Konje Source Type: research

Low sensitivity of the new FIGO classification system for electronic fetal monitoring to identify fetal acidosis in the second stage of labor?
I read with interest the paper entitled “Low sensitivity of the new FIGO classification system for electronic fetal monitoring to identify fetal acidosis in the second stage of labor” [1]. With the due respect, the title of the paper should be changed, according to the four points presented below. A title like “The FIGO-15 and the S WE-17 CTG classifications may have similar performances in detection of fetal acidosis in the second stage of labor”, would be more appropriate, considering the (clinical) impact that a title may always have. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 3, 2021 Category: OBGYN Authors: Jo ão Bernardes Tags: Correspondence Source Type: research

Syphilis in Pregnancy: The Impact of “the Great Imitator”
Syphilis remains a common congenital infection over the globe. There has been a tremendous rise in the number of congenital syphilis cases worldwide in the last 20 years. It affects large numbers of pregnant mothers in high burden regions causing a significantly high perinatal mortality and morbidity, which can be easily prevented by early antenatal screening and treatment.Diagnosis of maternal syphilis in pregnancy mainly based on clinical symptoms, serological tests and direct identification of treponemes in clinical samples. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 1, 2021 Category: OBGYN Authors: Alison Uku, Zahraa Albujasim, Tina Dwivedi, Zana Ladipo, Justin C. Konje Source Type: research

COVID-19 as an independent risk factor for subclinical placental dysfunction
The pandemic of the severe acute respiratory distress syndrome-associated Coronavirus-2 (SARS-CoV-2) has affected millions around the world. In pregnancy the dangers to the mother and fetus are still being explored. SARS-CoV2 can potentially compromise maternal and neonatal outcomes and this may be dependent on the pregnancy stage during which the infection occurs. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 29, 2021 Category: OBGYN Authors: Nishtha Jaiswal, Manju Puri, Kiran Agarwal, Smita Singh, Reena Yadav, Narendra Tiwary, Prerna Tayal, Barkha Vats Tags: Full length article Source Type: research

Hysteroscopic morcellation versus bipolar resection for removal of type 0 and 1 submucous myomas: a randomized trial
Since the introduction of hysteroscopic surgery, submucous myomas were preferably removed by the technique of hysteroscopic resection using electrosurgery. Although monopolar current may be more effective in cutting tissue, bipolar resection allows to use saline as irrigation fluid. The latter limits the risk of electrolyte disorders and allows for a larger fluid deficit (up to 2500  mL) and therefore more time to resect intrauterine pathology [1]. Nevertheless; hysteroscopic resection has some disadvantages, for example a rather long learning curve, a suboptimal view because of the formation of gas bubbles and swir...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 29, 2021 Category: OBGYN Authors: Steffi van Wessel, Hubertus A.A.M. van Vliet, Benedictus C. Schoot, Steven Weyers, Tjalina W.O. Hamerlynck Tags: Full length article Source Type: research

Obstetrics outcomes after complete and partial molar pregnancy: review of the literature and meta-analysis
The hydatidiform mole, also known as molar pregnancy, is a rare gynecological disease rising from the trophoblastic tissue with a ranging incidence of 0.6 to 11.5 per 1000 deliveries worldwide [1,2]. Two forms of molar pregnancy can be distinguished: (1) the complete hydatidiform mole (CHM) occurs when an enucleated egg is fertilized by two spermatozoa or one haploid duplicating spermatozoon; (2) the partial hydatidiform mole (PHM) occurs when a haploid egg is fertilized by two spermatozoa or one haploid duplicating spermatozoon [3]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 29, 2021 Category: OBGYN Authors: Capozzi Vito Andrea, Butera Diana, Armano Giulia, Monfardini Luciano, Gaiano Michela, Gambino Giulia, Sozzi Giulio, Merisio Carla, Berretta Roberto Tags: Full length article Source Type: research

Initial experience with positron emission tomography/computed tomography in addition to computed tomography and magnetic resonance imaging in preoperative risk assessment of endometrial cancer patients
Primary surgery for apparent early-stage endometrial cancer includes hysterectomy, bilateral salpingo-oophorectomy, and assessment of regional lymph node involvement. Lymph nodes are the most common site of extrauterine spread [1,2]. Detecting lymph node metastases in endometrial cancer is important for treatment and prognosis [3 –6]. It is debated if paraaortic nodes should be removed, and whether comprehensive lymphadenectomy improves prognosis, at the cost of increased complications [3,4,7]. The sentinel lymph node (SLN) strategy has emerged as a compromise between comprehensive lymphadenectomy in high-risk patien...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 29, 2021 Category: OBGYN Authors: Nina J Nordskar, Bj ørn Hagen, Aleksei Ogarkov, Ellen V Vesterfjell, Øyvind Salvesen, Guro Aune Tags: Full length article Source Type: research

Increase rate of ruptured tubal ectopic pregnancy during the COVID-19 pandemic
1.1 In an ectopic pregnancy (EP) there is implantation outside the uterus; in about 95% of cases this occurs in the Fallopian tubes [1]. The incidence of ectopic pregnancy is about 1% in women aged 24-44, and in Western countries 85% of cases are detected before they present with a rupture [2]. If not diagnosed at an early stage, it can lead to a gynecological emergency with substantial bleeding into the abdomen, hypovolemic shock and maternal death [3,4]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 29, 2021 Category: OBGYN Authors: Shira Dvash, Howard Cuckle, Ron Maymon Tags: Full length article Source Type: research

Monthly variation in univentricular heart and transposition of the great arteries – 10–year national population-based cohort study
(Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 28, 2021 Category: OBGYN Authors: Johanna Hautala, Mika Gissler, Annukka Ritvanen, Tero Vahlberg, Tiina Ojala Tags: Full length article Source Type: research

External Cephalic Version - A 10-year review of practice
Following the term breech trial (TBT), the incidence of Caesarean section secondary to breech presentations increased, from 76.9% to 89.7%. External Cephalic Version (ECV) is a safe effective method to reduce non-cephalic presentation at time of delivery. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 28, 2021 Category: OBGYN Authors: Emmanuel Hakem, Stephen W Lindow, Michael P O ’Connell, Günther von Bünau Tags: Full length article Source Type: research

Intravenous Immunoglobulin, Neonatal Alloimmune Thrombocytopenia, and Sjogren ’s Syndrome: A case report
A 35-year-old G3P1 woman presented at 12 weeks gestation for intravenous immunoglobulin infusion 1  g/kg/week as prophylaxis for a previous neonatal alloimmune thrombocytopenia. She was also treated with prednisone 20 mg three tablets a day. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 28, 2021 Category: OBGYN Authors: Georges El Hasbani, Rabih Chahine, Imad Uthman, Ali T. Taher Tags: Short communication Source Type: research

Home fetal heart rate monitoring in anti Ro/SSA positive pregnancies: literature review and case report
Anti-Ro/SSA antibodies are associated with a risk of 1-2% to develop complete atrioventricular block (AVB) in fetuses of positive mothers. Complete AVB is irreversible, but studies suggest that anti-inflammatory treatment during the transition period from a normal fetal heart rate (FHR) to an AVB might stop this progression and restore sinus rhythm. The most efficient method for diagnostic evaluation of this arrhythmia is the pulsed ‐Doppler fetal echocardiography.However, weekly or bi-weekly recommended fetal echocardiographic surveillance can rarely identify an AVB in time for treatment success, also because the transi...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 28, 2021 Category: OBGYN Authors: Roberta Milazzo, Elisa Ligato, Arianna Laoreti, Giulia Ferri, Ludovica Basili, Lisa Serati, Antonio Brucato, Irene Cetin Tags: Review article Source Type: research

Peak systolic velocity of Fetal middle cerebral artery to predict anemia in Red Cell Alloimmunization in un-transfused and transfused fetuses
To assess the accuracy of middle cerebral artery peak systolic velocity (MCA-PSV) in prediction of severe fetal anemia resulting from Red Cell Alloimmunization (Anti-D) in un-transfused and transfused fetuses. In addition to comparing the accuracy of MCA-PSV and the estimation of the daily decline of fetal hemoglobin (Hb), to determine the appropriate time of subsequent transfusions. Study (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 28, 2021 Category: OBGYN Authors: Shaimaa Abdelshafi, Ahmed Okasha, Sherif Elsirgany, Ahmed Khalil, Sara El-Dessouky, Nirvana AbdelHakim, Sherif Elanwary, Ahmad Elsheikhah Source Type: research

Blood pressure in a pregnant, rural Guatemalan population: results from a quality improvement database
Between 5 – 10% of pregnancies are estimated to be complicated by hypertensive disease.1 In Latin America, hypertension is estimated to be the maternal cause of death in 22.1% of fatalities in 2014.2 Surprisingly, epidemiologic data on hypertension in pregnancy is limited because of the heterogeneity of def initions.3 Prior studies carried out in Guatemala reported less than a 1% rate of pre-eclampsia in one setting, and a 8.3% rate of overall hypertensive disorders in another cohort.4,5 Because hypertension in pregnancy is a leading cause of death in Latin America and published data from Guatemala is sparse and vari...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 28, 2021 Category: OBGYN Authors: Margo S. Harrison, Angela Fought, Saskia Bunge Montes, Claudia Rivera, Amy Nacht, Andrea Jimenez Zambrano, Antonio Bolanos, Edwin Asturias, Stephen Berman, Gretchen Heinrichs Tags: Short communication Source Type: research

Preoperative Anemia Predicts Poor Prognosis in Patients with Endometrial Cancer: A Systematic Review and Meta-Analysis
Endometrial cancer is the leading gynecologic neoplasm in developed countries and the second most frequent one in developing countries [1]. It most frequently affects postmenopausal women, nonetheless, up to one-quarter of endometrial cancer patients are diagnosed prior to menopause [2]. Fortunately, the vast majority of cases ( ∼ 80%) are diagnosed at early stage disease and achieve favorable five-year overall survival (OS) rates close to 90% [3,4]. However, nearly 20% and 70% of patients with early and late stage disease, respectively, experience relapse post primary therapy [5]. (Source: European Journal of Obstetri...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 27, 2021 Category: OBGYN Authors: Ahmed Abu-Zaid, Osama Alomar, Mohamed Abuzaid, Saeed Baradwan, Hany Salem, Ismail A. Al-Badawi Tags: Review article Source Type: research

Factors Affecting Confidence and Competence of Doctors in performing Operative Vaginal Births: a Qualitative study
Operative vaginal birth (OVB) is an important skill for obstetricians. It is the most common emergency intervention in obstetrics [1], can reduce the risks associated with second stage caesarean section [2] and result in higher rate of spontaneous vaginal delivery in subsequent pregnancies [3]. OVB requires a high degree of skill [4]. It is recommended that the person performing an operative vaginal birth should demonstrate “adequate knowledge experience and skill to use the instruments and manage the complications should they arise” [5]· Training time before independent performance has markedly reduced ...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 27, 2021 Category: OBGYN Authors: Z Ashraf, L Crone, MF Higgins Tags: Full length article Source Type: research

Does pregnancy affect pelvic floor functional anatomy? A retrospective study
Pelvic organ prolapse (POP) is a common condition affecting women ’s quality of life, and has been attributed to pregnancy and vaginal delivery. [1,2] Although, major trauma to the pelvic organ supports seemed to occur exclusively in women who delivered vaginally, POP has also been observed in nulliparae and women who delivered exclusively via Caesarean Section (CS). POP in nulliparous women has been reported with a prevalence of 5%, and in majority, it co-existed with other forms of pelvic floor dysfunction such as urinary and defaecatory and sexual dysfunction, suggestive of the possible role of congenital aetiolog...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 27, 2021 Category: OBGYN Authors: Ixora Kamisan Atan, Wenyu Zhang, Ka Lai Shek, Hans Peter Dietz Tags: Full length article Source Type: research

Soluble endoglin concentration in maternal blood as a diagnostic biomarker of preeclampsia: a systematic review and meta-analysis
Preeclampsia is a main cause of maternal and fetal morbidity and mortality. Research about maternal circulating diagnostic biomarkers is continuously performed, often with conflicting results that necessitate quantitative synthesis. Objective of this meta-analysis is to examine the value of soluble endoglin as predictor of preeclampsia separately at each pregnancy trimester, therefore exploring its potential usage as diagnostic biomarker in preeclampsia. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 26, 2021 Category: OBGYN Authors: Georgia Margioula-Siarkou, Chrysoula Margioula-Siarkou, Stamatios Petousis, Kosmas Margaritis, Maria Alexandratou, Konstantinos Dinas, Alexandros Sotiriadis, Georgios Mavromatidis Tags: Review article Source Type: research

Benchmarking services in outpatient hysteroscopy (OPH): A quality improvement project
To develop a survey evaluating women ’s experience of outpatient hysteroscopy (OPH) to generate data to benchmark OPH practice in the UK that can be used to optimise women’s experience of OPH and improve services. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 25, 2021 Category: OBGYN Authors: Ayesha Mahmud, Paul Smith, T. Justin Clark Tags: Full length article Source Type: research

Perspectives of women on screening and prevention of CMV in pregnancy
Cytomegalovirus (CMV) is the most common cause of congenital infection and an important cause of sensorineural hearing loss and intellectual disability in children worldwide [1], but its importance is largely unknown to the general public. The prevalence of cCMV infection varies widely depending on maternal CMV seroprevalence, from 0.05 to 1 % [2]. Currently, there is no approved treatment that can be used to prevent cCMV infection when a pregnant woman is infected during pregnancy [3]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 25, 2021 Category: OBGYN Authors: Meggie Lallier Beaudoin, Christian Renaud, Marc Boucher, Fatima Kakkar, Soren Gantt, Isabelle Boucoiran Tags: Full length article Source Type: research

Assessment of the impact of an expectant management in case of abnormally progressing first-stage labor
To compare the cesarean section rate before and after the introduction of an expectant management protocol in patients with abnormally progressing first-stage labor. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 25, 2021 Category: OBGYN Authors: Yasmine Boukerfa-Bennacer, Marianne Perrot, Antoine Giraud, Adeline Dussot, B éatrice Trombert-Paviot, Céline Chauleur, Tiphaine Raia-Barjat Source Type: research

Do Obstetrics Trainees working hours affect caesarean section rates in normal risk women?
This study aimed to determine the effect of nocturnal hours and weekend on-call as well as the implementation of EWTD on our RG1 CS rates. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 23, 2021 Category: OBGYN Authors: Daniel Kane, Ita Shanahan, Michael Geary, Fergal D. Malone, Etaoin Kent, Naomi Burke Tags: Full length article Source Type: research

Comparing the effects of alcohol sclerotherapy with those of surgery on anti-M üllerian hormone and ovarian reserve after endometrioma treatment. A prospective multicenter pilot cohort study
To compare the effects of ultrasound-guided aspiration and ethanol sclerotherapy with those of laparoscopic surgery on anti-M üllerian hormone (AMH) levels and ovarian reserve in benign-appearing ovarian endometrioma. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 22, 2021 Category: OBGYN Authors: Jose M. Martinez-Garcia, Beatriz Candas, Elena Su árez-Salvador, Maria Gomez, Elisabet Merino, Marta Castellarnau, Manuel Carreras, Marta Carrarach, Neus Subirats, Santiago Gonzalez, Eulalia Fernández-Montolí, Jordi Ponce, Amparo Garcia-Tejedor Tags: Full length article Source Type: research

Assessing Lateral Uterine Wall Defects and Residual Myometrial Thickness After Cesarean Section
A history of cesarean section (CS) is associated with several long-term complications; however, uterine rupture remains one of the most important risks for subsequent pregnancy in women [1]. The risk of uterine rupture during a trial of labor is 0.7% and 1.6% after one and two CSs, respectively. The residual myometrial thickness (RMT) after CS is believed to be valuable for assessing the probability of ruptures. Women with RMT   (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 22, 2021 Category: OBGYN Authors: Ammar Al Naimi, Niki Mouzakiti, Bartosch Wolnicki, Frank Louwen, Franz Bahlmann Tags: Full length article Source Type: research

Optimal treatment strategies for small cell carcinoma of the uterine cervix: A retrospective multi-center study (KROG 19-03)
This multi-institutional study aimed to identify the optimal treatment strategy for small cell carcinoma of the cervix. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 22, 2021 Category: OBGYN Authors: Won Kyung Cho, Won Park, Young Seok Kim, Hyun-Cheol Kang, Jin Hee Kim, Kyung Su Kim, Kyu Hye Choi, Sei Kyung Chang, Ki Jung Ahn, Seok Ho Lee, Sunghyun Kim, Juree Kim, Keun-Yong Eom, Jeongshim Lee, Jong Hoon Lee, Jin Hwa Choi Tags: Full length article Source Type: research

Reply to letter to the editor entitled ‘Low sensitivity of the new FIGO classification system for electronic fetal monitoring to identify fetal acidosis in the second stage of labor?’
We appreciate the interest in our study, and the comments of Dr Bernardes, which we would like to respond to. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 22, 2021 Category: OBGYN Authors: Frida Ekeng ård, Monika Cardell, Andreas Herbst Tags: Correspondence Source Type: research

User evaluation of real-time CTG home monitoring: a pilot study
Cardiotocogram (CTG) home monitoring is perceived positively by pregnant women and independent midwives. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 19, 2021 Category: OBGYN Authors: Carlijn Lempersz, M. Beatrijs van der Hout-van der Jagt, Nicole Manders, Nicole Backx, Judith O.E.H. van Laar, S. Guid Oei Source Type: research