Evaluation of serum CA125, HE4 and CA724 and the risk of ovarian malignancy algorithm score in the diagnosis of high-grade serous ovarian cancer

Over the last 20  years, there has been a continuous increase in the number of cases of ovarian cancer, which is the most lethal gynaecological cancer. In 2020, there were approximately 300,000 new cases and 200,000 deaths worldwide due to ovarian cancer [1]. High-grade serous ovarian cancer (HGSOC) is the most co mmon and aggressive form, and is often found as distant metastasis at the time of initial diagnosis due to the lack of specific symptoms [2]. Compared with other histological types, HGSOC exhibits a higher tendency to recur and develop resistance to chemotherapy within 2 years of diagnosis [3].
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Full length article Source Type: research