Vaginal foreign body in the pediatric patient: A systematic review
Vaginal foreign objects represent a clinical and diagnostical challenge in pediatric gynecology, necessitating a thorough understanding of their clinical presentation and optimal management. Several case reports, case series and retrospective studies have been published, highlighting rare or complex cases. A recent narrative review that included patients with a self-inserted object up to the age of 20, presented an overview of 40 recent cases [1]. However, a comprehensive systematic review of literature is lacking. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 15, 2024 Category: OBGYN Authors: E. Umans, M. Boogaerts, B. Vergauwe, A. Verest, S. Van Calenbergh Tags: Review article Source Type: research

Effectiveness and safety of fezolinetant in alleviating vasomotor symptoms linked to Menopause.: A systematic review and Meta-Analysis
Menopause defined as the permanent cessation of ovarian function in women that occurs on average between the ages of 45 and 55  years is not a health condition [1]. It is a normal transition that most females naturally go through during their life and could be induced medically through chemotherapy interventions or surgically by bilateral oophorectomy [2,3]. The average age of menopause in the United States is between 51 and 52. Menopause occurs in approximately 5 % of women by the age of 45 while the majority will have completed their menstrual cycles by the time they reach age 60 [4]. (Source: European Journal of Obs...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 13, 2024 Category: OBGYN Authors: Ahmed A. Abo Elnaga, Mohamed A. Alsaied, Abdelrahman M. Elettreby, Alaa Ramadan Tags: Full length article Source Type: research

Transvaginal ultrasound with bowel preparation versus transvaginal ultrasound with bowel preparation and water contrast for diagnosing Recto-Sigmoid endometriosis. A systematic review and Meta-Analysis
Transvaginal ultrasound is effective in diagnosing endometriosis involving the rectosigmoid bowel. Some authors suggest enhanced detection of rectosigmoid involvement with bowel preparation. Conversely, conflicting views argue that bowel preparation may not improve diagnostic precision, yielding similar results to rectal water contrast. No existing meta-analysis compares these approaches. Our study aims to conduct a meta-analysis to evaluate the diagnostic performance of transvaginal ultrasound with bowel preparation, with and without rectal water contrast. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 11, 2024 Category: OBGYN Authors: Sara Madaruelo, Elena Satorres, Teresa Arruffat, Mariana Louren ço, Blanca Novillo-Del Álamo, Stefano Guerriero, Juan Luis Alcazar Tags: Review article Source Type: research

Endocan: A biomarker for endothelial dysfunction and inflammation, linking maternal obesity and pediatric obesity in a cohort of preterm neonates
The prevalence of obesity in reproductive aged women in the United States is approaching 40  %, and is thus the most common risk factor for pregnancy complications [1,2]. It has been well established that maternal obesity in pregnancy is associated with increased risks for the mother and the neonate. Maternal risks include gestational diabetes, preeclampsia, sleep apnea, cesarean section , venous thromboembolism, wound dehiscence, and epidural anesthesia failure [2,3]. Fetal and neonatal risks include congenital anomalies, difficulty in ultrasonographic diagnosis of anomalies, increased likelihood of cell free fetal DNA ...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 11, 2024 Category: OBGYN Authors: E. Holthaus, M. O'Neill, W. Jeske, P. DeChristopher, J. Goodman, L. Glynn, S. Levin, J. Muraskas Tags: Full length article Source Type: research

Successful management of fetal hypoxia due to amniotic banding at 26 weeks of pregnancy: A case report of a rare survival
Amniotic banding is a rare condition that can lead to structural limb anomalies, fetal distress and adverse obstetric outcomes. The main hypothesis for its etiology is a rupture of the amniotic membrane in early pregnancy, with the formation of tightly entangling strands around the fetus. These strands can constrict, incise, and subsequently amputate limb parts, the neck or head. More rarely, the amniotic banding can affect the umbilical cord, leading to fetal distress or potential intra-uterine fetal demise (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 11, 2024 Category: OBGYN Authors: Florian Waerlop, Isabelle Dehaene, Kristien Roelens Source Type: research

Brief Communication: A case report of dilation and evacuation for cephalopagus conjoined twin pregnancy at 22 weeks
We recently encountered an interesting case of a 24  year old gravida 1 para 0 patient who presented with known cephalopagus conjoined twins at 22 weeks 1 day gestational age desiring dilation and evacuation (D&E) for termination of pregnancy. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 10, 2024 Category: OBGYN Authors: Megan Masten, Paige Kendall, Rebecca Cohen Source Type: research

Deep neural network (DNN) modelling for prediction of the mode of delivery
One of the factors that worry obstetricians the most is the method of delivery. Overall, vaginal birth is the most typical method of childbirth, followed by vacuum extraction, forceps delivery, and emergency caesarean sections [1]. Each of these birthing scenarios has advantages and disadvantages, and the style of delivery chosen might not be appropriate given the mother's personality. The potential risks of using the incorrect delivery method include fetal termination, heavy bleeding, respiratory issues for the infant, and others. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 10, 2024 Category: OBGYN Authors: Ananya Kuanar, Abdul Akba, Sujata Pendyala, Dattatreya Kar Tags: Full length article Source Type: research

The deadlock on HPV vaccination in Japan is almost broken!
Primary and secondary prevention have the potential to eliminate cervical cancer. On 17 November 2020, the World Health Organization (WHO) launched a global strategy for the accelerated elimination of cervical cancer [1]. By the end of the century, the WHO wants to reduce the cervical cancer incidence below 4 per 100,000 women. The strategy is based on three pillars: (1) vaccination: 90% of girls fully vaccinated with the HPV vaccine by the age of 15; (2) screening: 70% of women screened using a high-performance test by the age of 35, and again by the age of 45; (3) treatment: 90% of women with pre-cancer treated and 90% o...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 9, 2024 Category: OBGYN Authors: Wiebren A.A. Tjalma, Ryo Konno, Jaques van Heerden Source Type: research

N-terminal prohormone of brain natriuretic peptide in gestational hypertension and preeclampsia – State of the art
Hypertensive disorders of pregnancy (HDPs) constitute one of the most common disorders in pregnant women. It comprises gestational hypertension (GHTN) and preeclampsia (preE). According to the World Health Organization, in developed countries, 16  % of maternal deaths are attributed to hypertensive disorders [1]. GHTN is defined as elevated blood pressure (BP) (systolic BP [SBP] ≥ 140 mmHg and/or diastolic BP [DBP] ≥ 90 mmHg) after 20 gestational weeks, persisting for less than 12 weeks postpartum. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 8, 2024 Category: OBGYN Authors: Natalia Ros ół, Grzegorz Procyk, Joanna Kacperczyk-Bartnik, Marcin Grabowski, Aleksandra Gąsecka Tags: Review article Source Type: research

A simulation study to assess the potential benefits of MRI-based fetal weight estimation as a second-line test for suspected macrosomia
Macrosomia, defined as a birth weight (BW) above 4000 or 4500  g [1,2], is associated with adverse maternal and neonatal outcomes. Maternal complications include increased rates of birth operative vaginal delivery or cesarean delivery (CD) due to abnormal first and second stage stages of labor, extensive genital tract lacerations, and postpartum hemorrhage. Potential neonatal complications include shoulder dystocia (SD), birth trauma, neonatal hypoglycemia, and other long-term metabolic disorders [3]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 8, 2024 Category: OBGYN Authors: Dominique A. Badr, Andrew Carlin, Michel Boulvain, Caroline Kadji, Mieke M. Cannie, Jacques C. Jani, Leonardo Gucciardo Tags: Full length article Source Type: research

A randomized, prospective, controlled study comparing uterine preserving laparoscopic lateral suspension with mesh versus laparoscopic sacrohysteropexy in the treatment of uterine prolapse
Pelvic organ prolapse (POP) significantly affects women's quality of life, occurring in 20 –30% of females aged over 20 globally. With aging populations, demand for pelvic reconstructive surgery is rising. Patients seek anatomical restoration while preserving uterus and sexual function. Sacrohysteropexy is the gold standard for apical prolapse, but carries risks. Lateral suspension, off ers safer apical and anterior correction especially for obese, sexually active women. Our prospective study compares laparoscopic sacrohysteropexy and lateral suspension objectively and subjectively. (Source: European Journal of Obstetric...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 7, 2024 Category: OBGYN Authors: Ozan Do ğan, Murat Yassa, Ecem Eren, Pınar Birol İlter, Niyazi Tuğ Tags: Full length article Source Type: research

Surgical evacuation with intraoperative ultrasound (SEE U): A randomised controlled trial
First trimester miscarriage is common affecting 1 in 9 pregnancies [1]. Surgical management of miscarriage (SMM) remains one of the most common surgical procedures with one third of miscarriages managed surgically [2]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 7, 2024 Category: OBGYN Authors: Paul P. Smith, Versha Cheed, Lee Middleton, Adam J. Devall, Firaz Izzat, T. Justin Clark Tags: Full length article Source Type: research

Extended-release versus oral buprenorphine as opioid maintenance treatment during pregnancy-maternal and neonatal outcomes
The prevalence of pregnant individuals with opioid use disorder continues to increase posing health risks to women, fetuses, and children as well as challenges and costs to society [1]. Opioid maintenance treatment during pregnancy is beneficial and widely recommended but carries risks, hence knowledge of the safety profiles of pharmacotherapies is required [2]. Neonates exposed to buprenorphine may experience less severe neonatal opioid withdrawal syndrome than those exposed to methadone [3,4]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 6, 2024 Category: OBGYN Authors: Minna Kanervo, Sarimari Tupola, Eeva Nikkola, Krista Rantakari, Hanna Kahila Tags: Full length article Source Type: research

Prenatal chromosomal microarray analysis and karyotyping in fetuses with isolated choroid plexus cyst: A retrospective case-control study
Choroid plexus cyst (CPC) is a cystic anechoic region in choroid plexus of fetal lateral ventricle. It is one of the common sonographic soft markers in the second trimester, which was first reported by Chudleigh et al. in 1984. Later, Nicolaides et al. pointed out that CPC is related to trisomy 18 [1,2]. In the second trimester, CPC can be found in 1  %-2% of normal fetuses, of which more than 90 % disappear after 28 weeks of gestation and only a few show progressive enlargement [3,4]. CPC is not equivalent to fetal malformation. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 6, 2024 Category: OBGYN Authors: Linlin Wang, Ping Liang, Pingshan Pan, Jiasun Su, Jiayi Qin, Zhaoxia Chen, Dongbing Huang, Weijia Sun, Pengshu Song, Hongwei Wei Tags: Full length article Source Type: research

Immunotherapy combined with targeted therapy in advanced small cell carcinoma of the ovary of hypercalcemic type: A case of overall survival lasting for over 5  years
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a rare but highly aggressive ovarian malignant neoplasm lacking a unified clinical management process. Most patients are diagnosed at an advanced stage and have an extremely poor prognosis with an overall probability of survival less than 10  %. Here, we describe the case of a patient with advanced SCCOHT achieved a survival of over 5 years after receiving multiple cycles of immunotherapy combined with anti-angiogenic therapy or CDK4/6 inhibitors. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 5, 2024 Category: OBGYN Authors: Yi Gao, Li Zang, Yingfei Ye, Fenghua Ma, Mingyi Kang, Kewei Zheng, Yu Kang, Haitao Wang, Congjian Xu Tags: Correspondence Source Type: research