Urinary sFlt-1 and PlGF as preeclampsia predictors: sFlt-1/creatinine ratio improves the prediction value
Preeclampsia is a hypertensive pregnancy disorder that complicates 2 –4 % of pregnancies [1] and a leading cause of maternal and fetal morbidity and mortality that involves a high risk of preterm delivery, fetal growth restriction (FGR), placental abruption and stillbirth [1,2]. FGR is defined by an estimated fetal weight (EFW) below the 3rd centile or below the 10th centile and pathological Doppler [3–5]. FGR and preeclampsia are frequently associated and both of them display placental underperfusion and an anti-angiogenic profile [6]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - May 6, 2024 Category: OBGYN Authors: Giovanna Mart ín-Palumbo, Marta Duque Alcorta, Marta Pérez de Aguado, Eugenia Antolín, José Luis Bartha Tags: Full length article Source Type: research

Impact of double trophectoderm biopsy on reproductive outcomes following single euploid blastocyst transfer
Advances in reproductive technologies have led to increased utilization of embryo biopsy for preimplantation genetic testing for aneuploidy (PGT-A) [1,2], monogenic (PGT-M) diseases or structural rearrangements (PGT-SR). The aim is to transfer embryos with known favourable genetic constitution. Since its inception in the 1990s [3], embryo biopsy has rapidly evolved with the introduction of trophectoderm biopsy [4] and the use of advanced platforms, such as next-generation sequencing (NGS) and microarray comparative genomic hybridization (aCGH) [5,6]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - May 6, 2024 Category: OBGYN Authors: Efstathios Theodorou, Elpiniki Chronopoulou, Ozkan Ozturk, Xavier Brunetti, Paul Serhal, Jara Ben-Nagi Tags: Full length article Source Type: research

Cervical elastography using e-cervix for prediction of preterm birth in twin pregnancies with threatened preterm labor
Preterm birth is the most common cause of perinatal morbidity and mortality [1 –3]. Several strategies have been studied for the management of preterm birth [4–34]. Most of these were evaluated in high risk singleton pregnancies, such as women with shortened length of uterine cervix. Many studies in literature support the use of vaginal progesterone in such subset populati on [4,35]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - May 4, 2024 Category: OBGYN Authors: Giovanni Nazzaro, Gabriele Saccone, Marilena Miranda, Alessandra Ammendola, Giorgia Buonomo, Daniele Neola, Giorgia Bartolini, Mariavittoria Locci Tags: Full length article Source Type: research

Probe motion during mid-trimester fetal anomaly scan in the clinical setting: A prospective observational study
Ultrasound is a dynamic, real-time imaging modality widely used for pregnancy screening, but it can be challenging depending on operator ’s level, fetal presentation, and patient body mass index (BMI). In accordance with the latest International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) guidelines, routine mid-trimester fetal ultrasound examination includes an evaluation of the following: cardiac activity, number o f fetuses, fetal size, basic fetal anatomy including head, face, heart, abdomen, limbs (skeletal), umbilical cord, genitalia, placental appearance and location, and amniotic fluid volume [1]. ...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - May 3, 2024 Category: OBGYN Authors: Maela Le Lous, Francisco Vasconcelos, Chiara Di Vece, Brian Dromey, Raffaele Napolitano, Soojoeong Yoo, Eddie Edwards, Arnaud Huaulme, Donald Peebles, Danail Stoyanov, Pierre Jannin Tags: Full length article Source Type: research

Patient-initiated follow-up in gynaecology: Patient and clinician views
Outpatient hospital appointments in the UK have almost doubled in number in the last decade. Two-thirds of outpatient appointments in the UK are for follow-up after a previous consultation [1,2]. Up to 20  % of these appointments are unattended (patient did not attend), impacting valuable resources and impacting long waiting times and declining patient satisfaction [3]. The NHS in the UK spends £8 billion a year running outpatient services [2]. Changes to service delivery in order to curb this dem and to sustainable levels are a key area of interest [4,5]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - May 1, 2024 Category: OBGYN Authors: Mira Chainrai, Victoria F. Kershaw, Thomas G. Gray, Stephen C. Radley Tags: Full length article Source Type: research

Literature review on the bilateral occurrence of invasive lobular breast cancer
Invasive lobular carcinoma (ILC) is a type of breast cancer characterized by the loss of E-cadherin expression, leading to discohesion between tumour cells [1]. This phenomenon explains the multifocal growth pattern and diffuse infiltration observed in ILC [2,3]. ILC is the second most common histological type of invasive breast cancer, following invasive breast cancer of no special type (NST) [4]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 30, 2024 Category: OBGYN Authors: Griet Verboven, Imke Lodewijkx, Laura Van den Bosch, Manon Huizing, Mireille Van Goethem, Glenn Broeckx, Wiebren A. Tjalma Tags: Full length article Source Type: research

Intermediate-risk endometrial cancer treated with adjuvant brachytherapy using single dosimetric planning: long-term outcome and toxicity assessment
The incidence of endometrial carcinoma has increased steadily over the past three decades, emerging as the second most commonly diagnosed gynaecological cancer worldwide, and the most common gynaecological malignancy in high-income countries [1]. It is most commonly diagnosed in early stages, where the 5-year specific survival rate reaches 95%. Nevertheless, the number of deaths related to endometrial cancer continues to rise, despite an increase in global cancer survival rates [2]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 30, 2024 Category: OBGYN Authors: Abel Cordoba, El Hajj Houssein, Alexandre Escande, Cyrielle Scouarnec, Fabrice Narducci, Carlos Martinez Gomez, Eric Leblanc, Delphine Hudry, Camille Pasquesoone, Sophie Taieb, Xavier Mirabel, Eric F. Lartigau, Florence Le Tinier Tags: Full length article Source Type: research

Retrospective cohort study on the bilateral occurrence of invasive lobular breast cancer
Breast cancer is a prevalent and significant health concern globally. It is crucial to conduct research to enhance our understanding of this disease, particularly in Belgium. Belgium holds the highest age-standardized incidence rate for breast cancer worldwide [1]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 30, 2024 Category: OBGYN Authors: Griet Verboven, Laura Van den Bosch, Imke Lodewijkx, Manon Huizing, Mireille Van Goethem, Glenn Broeckx, Wiebren A. Tjalma Source Type: research

EUROPEAN ASSOCIATION OF PERINATAL MEDICINE (EAPM) Position statement: Screening, diagnosis and management of congenital anomalies of the umbilical cord
Congenital anomalies of the umbilical cord are associated with an increased risk of pregnancy and perinatal complications. Some anomalies of the cord have a higher prevalence than other fetal structural anomalies. The most common anomalies are the absence of an umbilical artery and velamentous insertion of the cord (with or without vasa previa). These anomalies, even when not associated with fetal structural defects, increase the risk of adverse perinatal outcome including, fetal growth restriction and stillbirth. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 30, 2024 Category: OBGYN Authors: Eric Jauniaux, Cathrine Ebbing, Yinka Oyelese, Rony Maymon, Federico Prefumo, Amar Bhide Tags: Expert Opinion Source Type: research

How pregnant women with diabetes experience telemonitoring of the fetal heart rate – An interview study
In complicated pregnancies, the rising focus on telehealth has made foetal monitoring at home an alternative to hospitalization or frequent outpatient clinic visits [1]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 29, 2024 Category: OBGYN Authors: Ingrid Jepsen, Jane H. Nielsen, Stine A. Eriksen, Rikke D. Maimburg Tags: Full length article Source Type: research

Chromosomal abnormalities study for anembryonic pregnancy by BACs-on-Beads technique
Approximately 15 –20 % of all clinically recognized pregnancies end in first-trimester loss/miscarriage, with live birth occurring in only 30 % of all pregnancies [1,2]. The World Health Organization (WHO) and the Center for Disease Control and Prevention (CDC) define miscarriage as the loss of a pregnancy bef ore 20 weeks of gestation or the ejection or removal of an embryo or fetus that weighs 500 g or less, with most miscarriages happening during the first trimester of pregnancy. Anembryonic pregnancy (AP) or blighted ovum is a non-viable condition causing 50 % of all miscarriages. (Source: European Journal ...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 29, 2024 Category: OBGYN Authors: Preyaporn Onsod, Watcharapa Jaranasaksakul, Takol Chareonsirisuthigul, Rachanee Parinayok, Budsaba Rerkamnuaychoke, Prapatsorn Areesirisuk Tags: Full length article Source Type: research

Analysis of MRI brain biometrics in fetuses monitored for intra uterine growth restriction and their prognostic value: Results of a prospective multicenter study
Intra uterine growth restriction is a public health, with a variable incidence estimated at nearly 10  % of births in developed countries [1,2] and up to 34 % in emerging countries [3] with a recent estimation of nearly 32 million cases worldwide per year [4,5]. This pathology is associated with increased neonatal morbimortality [6]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 29, 2024 Category: OBGYN Authors: Eric Xu, Jean-Marie Jouannic, Marianne Alison, Pierre-Yves Ancel, St éphanie Friszer, Jessica Rousseau, Lucie Guilbaud, Catherine Adamsbaum, François Goffinet, Eléonore Blondiaux Tags: Full length article Source Type: research

Musculoskeletal evaluation of the lower pelvic complex in women with endometriosis: A case-control study
Endometriosis is a chronic inflammatory disease defined by the presence and growth of estrogen-dependent endometrial tissue outside the uterine cavity [1]. Pelvic pain is its most important symptom and can be clinically present as dysmenorrhea, dyspareunia, dysuria, dyschezia and chronic pelvic pain (CPP) [2].Table 1. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 29, 2024 Category: OBGYN Authors: Adriana Silva de Barros, Germana Mesquita Magalh ães, Luana Darc de Menezes Braga, Mariana Oliveira Veloso, Pedro Olavo de Paula Lima, Rayane Moreira da Cunha, Samuel Soares Coutinho, Simony Lira do Nascimento, Leonardo Robson Pinheiro Sobreira Bezerra Tags: Full length article Source Type: research

Subserosal pregnancy: Systematic review with proposal of new diagnostic criteria and ectopic pregnancy classification
Ectopic pregnancies (EPs), defined as pregnancies where the growing blastocyst implants outside the endometrial cavity[1], have an incidence which varies consistently across different populations and studies, so that their rate cannot be precisely established. This considered, 0.5 –1 % of all pregnancies are supposed to be ectopic[2]. The most common extrauterine implant location is the fallopian tube[3]. Non-tubal pregnancies (NTP) account for less than 5 % of all EP[4]. NTP are accompanied by a 7–8 times higher risk of maternal mortality when compared to tubal pregn ancies[5], and their treatment might sometimes ...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 29, 2024 Category: OBGYN Authors: Guglielmo Stabile, Francesco Cracco, Giulia Zinicola, Stefania Carlucci, Francesco Mangino, Tamara Stampalija, Giuseppe Ricci Tags: Review article Source Type: research

Choice and factors associated to the use of contraceptive methods among postpartum women: A prospective cohort study
There is a need for effective strategies to reduce the high rates of unplanned pregnancies. Encouraging contraception in the immediate postpartum period and offering the method may contribute to modifying the current scenario of vulnerability. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 28, 2024 Category: OBGYN Authors: Elaine Meireles Castro Maia, Raquel Autran Coelho Peixoto, Cristina Aparecida Falbo Guazzelli Tags: Full length article Source Type: research