Prenatal chromosomal microarray analysis and karyotyping in fetuses with isolated choroid plexus cyst: A retrospective case-control study

Choroid plexus cyst (CPC) is a cystic anechoic region in choroid plexus of fetal lateral ventricle. It is one of the common sonographic soft markers in the second trimester, which was first reported by Chudleigh et al. in 1984. Later, Nicolaides et al. pointed out that CPC is related to trisomy 18 [1,2]. In the second trimester, CPC can be found in 1  %-2% of normal fetuses, of which more than 90 % disappear after 28 weeks of gestation and only a few show progressive enlargement [3,4]. CPC is not equivalent to fetal malformation.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Full length article Source Type: research