Transvaginal natural orifice transluminal endoscopic surgery for myomectomy: A more suitable surgical approach for enhanced recovery after surgery
Uterine fibroids constitute one of the most prevalent benign tumors of the female reproductive system, with an incidence rate that can reach up to 30  ∼ 70 % [1]. Uterine fibroids generally remain asymptomatic, often being incidentally discovered during routine gynecological examinations. However, as the fibroids progressively enlarge, patients may encounter distinct clinical presentations depending on the fibroid’s location, such as ab normal uterine bleeding, infertility, abdominal distension, and compression-related symptoms (e.g., urinary or bowel difficulties), significantly compromising patients’ overall ...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 7, 2024 Category: OBGYN Authors: Wei Cheng, Xin Li, Tianjiao Liu, Aijie Xie, Xian Wu, Jianmei Liao, Xiaoyan Liao, Yujian Jia, Xine Zhou, Ying Liu, Yan Liu, Jie Yu, Ziru Yan, Juan Huang, Yalan Li, Xue Xiao, Yonghong Lin, Xiaoqin Gan Tags: Full length article Source Type: research

Artificial intelligence based cardiotocogram assessment during labor
The cardiotocogram (CTG) is currently the most widely used method to assess the fetal condition during labor. However, since its introduction, the clinical value of CTG has been debated. Its introduction has not decreased the incidence of severe complications (e.g., cerebral palsy), except neonatal seizures [1]. The use of continuous CTG monitoring in the search for fetal compromise has therefore been associated with a strong increase in Caesarean sections and instrumental vaginal births [1]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 7, 2024 Category: OBGYN Authors: Raoul Melaet, Ivar R. de Vries, Ren é D. Kok, S. Guid Oei, Iris A.M. Huijben, Ruud J.G. van Sloun, Judith O.E.H. van Laar, Rik Vullings Tags: Full length article Source Type: research

Expression levels of ADAMTS 5, 9, and 12 in endometrial polyps and their predictive value for the diagnosis and recurrence of endometrial polyps
Endometrial polyps (EPs) are characterized as localized overgrowth of endometrial glands and mesenchyme [1]. Histologically, EPs exhibit features such as a fibrotic stroma, thickening of blood vessels, and irregular glandular hyperplasia [2]. EPs are the most common type of gynecologic polyps, with a prevalence of 7.8  %–50 %, and EPs are highly prone to recurrence, with a recurrence rate of 2.5 %–43.6 % [3]. The primary symptoms of EPs can include abnormal uterine bleeding, infertility, abdominal pain, and vaginal discharge. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 7, 2024 Category: OBGYN Authors: Jiejie Nian, Yuqing Zhu, Xiaoli Lv, Yue Zhang, Zhongkai Xue, Zhongran Wu, Yujia Zhou, Yu Liu Tags: Full length article Source Type: research

Prevalence of overactive bladder among overweight and obese women: A prospective cross-sectional cohort study
Overactive bladder (OAB) is an entity that affects and negatively impacts the quality of life (QoL) and sexual function of approximately 12  % of the adult female population [1]. The International Urogynecological Association (IUGA) and the International Continence Society (ICS) define urinary urgency as a complex of symptoms defined by increased daytime frequency and nocturia with or without urinary incontinence in the absence of pat hologic or metabolic conditions that may explain these symptoms [2]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 5, 2024 Category: OBGYN Authors: Baydaa Alsannan, Antonio Simone Lagan à, Jehad Alhermi, Shaikha Almansoor, Amal Ayed, Renato Venezia, Andrea Etrusco Tags: Full length article Source Type: research

Omega-3 fatty acid supply in pregnancy for risk reduction of preterm and early preterm birth: A Position Statement By the European Board and College of Obstetrics and Gynaecology (EBCOG)
Pre-term birth is associated with significant neonatal morbidity and mortality. Pre-term births are associated with significant health and neuro -developmental risks in childhood and adulthood. Women with multiple pregnancies are at much higher risks. Low levels of omega-3 long-chain polyunsaturated fatty acids (PUFAs), such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are associated with higher risk of pre-term labour and increased consumption of foods rich in omega-3 PUFA or supplements are associated with a 11% and 42% risk reduction of early and late preterm births, respectively. (Source: European Jour...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 5, 2024 Category: OBGYN Authors: Charles Savona-Ventura, Tahir Mahmood, Sambit Mukhopadhyay, Frank Louwen Tags: Expert Opinion Source Type: research

Errors in the classification of pregnant women according to Robson ten-group classification system
The Ten-Group Classification System (TGCS) or Robson classification was proposed in 2001 by Michael Robson and has been recommended by the World Health Organization (WHO) since 2015 for comparison of Caesarean section (CS) rates in different settings [1,2]. The TGCS has gained popularity in recent years and is nowadays more commonly used for analysis, audit, and comparison of CS rates and other perinatal events in and between healthcare facilities [1,3 –6]. The TGCS was found to be the best classification to meet local and international needs [7]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 5, 2024 Category: OBGYN Authors: Deirdre Marlene Gantt, Bj örn Misselwitz, Vinzenz Boos, Anke Reitter Tags: Full length article Source Type: research

Is salivary uric acid, a putative biomarker of pre-eclampsia, of maternal, placental, or fetal origin?
Pre-eclampsia (PE), and fetal growth restriction (FGR), are severe complications of pregnancy, and leading causes of maternal and fetal morbidity and mortality [1]. Pre-eclampsia is defined as de novo onset of hypertension after 20 gestational weeks combined with either proteinuria, organ dysfunction, or FGR [2], while FGR, defined as a fetus not meeting its genetic growth potential, is an ultrasound-based diagnosis that also can arise without hypertension [3]. Pre-eclampsia is considered to be a heterogeneous disorder with different subtypes [4], variable clinical presentation, and a variable course of evolution, includin...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 4, 2024 Category: OBGYN Authors: Ida Catharina P üschl, Meera Thaneswaran Vyramuthu, Lisbeth Bonde, Morten Lebech, Hiba Iraqi Møller, Thomas Vauvert F. Hviid, Bjarke Lund Sørensen, Nicholas S. Macklon Tags: Full length article Source Type: research

Assessment of the cerebroplacental ratio and uterine arteries in low-risk pregnancies in early labour for the prediction of obstetric and neonatal outcomes
Intrapartum fetal hypoxia is among the leading causes of perinatal death and neonatal encephalopathy [1]. The evidence-based management of human labour includes the antepartum identification of patients at risk for intrapartum hypoxia, which is based on the evaluation of maternal medical and obstetric history in association with antepartum sonographic parameters, including fetal biometry [2,3]. However, available data has shown that most cases of hypoxic-related labour complications occur among pregnancies classified at low-risk [4 –6]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 4, 2024 Category: OBGYN Authors: Andrea Dall'Asta, Tiziana Frusca, Giuseppe Rizzo, Ruben Ramirez Zegarra, Christoph Lees, Francesc Figueras, Tullio Ghi Tags: Full length article Source Type: research

Cumulative oxytocin dose in spontaneous labour – Adverse postpartum outcomes, childbirth experience, and breastfeeding
1.1 National guidelines exist for indications of oxytocin infusion and correct infusion regimens to reduce potential side effects but does not propose a safe maximum cumulative oxytocin dose during labour [1 –2]. Oxytocin infusion during labour has been associated with long labours [3], emergency caesarean sections (CS), post-partum haemorrhages (PPH), obstetric anal sphincter injuries (OASI), low umbilical-cord arterial pH and increased risk for admission to Neonatal Intensive Care Unit [4–5]. Furt hermore, oxytocin augmentation has been related to a negative birth experience [5] and with lower rates of exclusive brea...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 2, 2024 Category: OBGYN Authors: Cecilia Br üggemann, Sara Carlhäll, Hanna Grundström, Anna Ramö Isgren, Marie Blomberg Tags: Full length article Source Type: research

The communicating rudimentary horn of the unicornuate uterus as a rare localization of a partial hydatidiform mole and the diagnostic challenge
Background& aims: A unicornuate uterus with a rudimentary horn, with an incidence of 0.06%, is the consequence of an anomaly during the development of Mullerian ducts. This carries significant pregnancy risks, especially when implantation occurs in the rudimentary horn. A pregnancy complication characterized by an abnormal growth of trophoblasts, such as molar pregnancy is rare at this location. This case-based article aims to emphasize the rarity and the methods of diagnosis of a unicornuate uterus and a hydatidiform mole. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 1, 2024 Category: OBGYN Authors: Agata Natka ńska-Małeka, Adrianna Skrajna, Małgorzata Reinholz-Jaskólska Source Type: research

Resectoscopic surgery: a 5-year audit of over a thousand procedures at a central hospital
Introduction and aimsof the study: Endometrial polyps and submucous myomas are two of the most frequent pathologies in Gynaecology. Resectoscopy is a surgical technique performed in order to treat these pathologies, allowing access to the uterine cavity, confirmation of the diagnosis and removal of the lesions at the same operative time. Sometimes this technique is performed an incomplete or unsuccessful office hysteroscopy, and it is frequently performed in an outpatient setting. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 1, 2024 Category: OBGYN Authors: Margarida Cordoeiro, Sara Sales, Renata Ver íssimo, Marta Fernandes, Nuno Nogueira Martins Source Type: research

Metabolome analysis as a potential source of biomarkers in endometriosis
Introduction and aimsof the study: Endometriosis is a disease that affects approximately 190 million women. There is a demand for developing a non-invasive diagnostic tool of endometriosis. Diseases cause disruption of biochemical pathways leading to a metabolic fingerprint characteristic of its site and nature. This makes metabolomics a powerful tool for development of biomarkers. Thus, the aim of our study was to analyse the differences in metabolomic profile of endometriosis patients and controls. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 1, 2024 Category: OBGYN Authors: Cezary Wojty ła, Grzegorz Mańka, Mariusz Kiecka, Piotr Laudański Source Type: research

UROCORTIN 1 (UCN 1) as a possible biomarker in differentiation of endometriosis stage and distinguishing its deep infiltration phenotype
Introduction and aims of the study: Endometriosis is a chronic, estrogen-dependent disease characterized with the presence of endometrial tissue outside the uterine cavity. Its etiology is multifactorial and depends on coexistence of immune, genetic, as well as environmental factors. Due to the Urocortin 1 (Ucn1) expression in various parts of the female genital tract i.e. endometrium, its role in disease pathophysiology is suspected. The aim of our study was to investigate the concentrations of Ucn1 in blood and peritoneal fluid samples in women with endometriosis and to find correlations between Ucn1 and immune cells or ...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 1, 2024 Category: OBGYN Authors: Monika Abramiuk, Karolina Frankowska, Krzysztof Ku łak, Ewelina Grywalska, Rafał Tarkowski Source Type: research

Prevalence of adenomyosis in women undergoing hysterectomy in a Greek secondary hospital – A retrospective study
Introduction and aims of the study: To describe the prevalence of adenomyosis in hysterectomy specimens and its correlation to the respective indication of hysterectomy. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 1, 2024 Category: OBGYN Authors: Konstantinos Zacharis, Spyridon Chondros, Vasiliki-Kalouda Tsapadikou, Asimina Barbarousi, Ismini Anagnostaki, Eleni Chrysafopoulou, Stavros Kravvaritis, Eirini Pathiaki, Anastasia Fouka, Theodoros Charitos Source Type: research

Differences in endometrial and cervical microbiome of uterine fibroids patients – A preliminary study
Introduction: Uterine fibroids (UFs) are the most common pelvic tumors in women of reproductive age. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 1, 2024 Category: OBGYN Authors: Lidia Korczy ńska, Natalia Żeber-Lubecka, Maria Kulecka, Katarzyna Bagińska, Maria Głowienka, Magdalena Zgliczyńska, Michał Ciebiera Source Type: research