Topical delivery of drugs in the treatment of high-grade cervical squamous intraepithelial lesions: A meta-analysis
High-grade squamous intraepithelial lesions (HSIL) and adenocarcinoma in situ (AIS) are precancerous changes of cervical cancer. HSIL including cervical intraepithelial neoplasia grade 2 (CIN2) and grade 3 (CIN3) is usually caused by high-risk human papillomavirus (HR-HPV) infection. The transformation from HR-HPV infection to cervical cancer generally takes several decades. Thus, effective treatment and management of HSIL are essential to the secondary prevention of cervical cancer. Screening is an important strategy for detecting CIN. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 20, 2024 Category: OBGYN Authors: Shixuan Liu, Wenlei Zhang, Wenyan Wang, Jianlan Zheng Tags: Full length article Source Type: research

Mid-trimester sonographic placenta previa thickness and persistence at delivery
The incidence of placenta previa and placenta accreta spectrum (PAS) disorders have increased over the years largely secondary to increased cesarean delivery rates, reproductive assistance, and various uterine procedures such as myomectomy, septum resection, and lysis of intracavitary bands [1,2]. The reported incidence of placenta previa is approximately 1 in 200 and PAS is approximately 1 in 300 to 1 in 533, however these incidences can vary largely based on patients factors such as prior uterine surgery [3 –6]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 19, 2024 Category: OBGYN Authors: Minhazur R. Sarker, Henri M. Rosenberg, Leslie Warren, Lauren Ferrara, Angela Bianco, Chelsea A. Debolt Tags: Full length article Source Type: research

Ultrasound appearance of a hemostatic agent in the ovary during follow-up
Dear Editor, (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 19, 2024 Category: OBGYN Authors: Sara Tameish, Henar Guerra Mas, Sandra Sim ón Cases, Alba Cabello Magriñá Source Type: research

In endometriosis-related pneumothorax surgery, presence of endometriotic nodules increases postoperative air leaks and long-term relapse
Catamenial pneumothorax (CP) represent between 20 and 35  % of premenopausal pneumothorax and is related to endometriosis in 50 % of cases [1,2]. Endometriosis-related non-catamenial pneumothorax (ER non-CP) represent between 6 and 10 % of pneumothorax among women of child bearing age [2–6]. Macroscopic and pathological lesions, described in both CP and ER non-CP, include diaphragmatic defect and pleural nodules [7–10]. These macroscopic lesions impact surgical management. During follow-up, CP and ER non-CP are associated with higher rate of postoperative recurrence and prolonged air leaks compared to idiopathic ...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 19, 2024 Category: OBGYN Authors: Justin Issard, Cl émence Vaudelin, Diane Imberton, Anna Vayssette, Marielle Leroux, Mihaela Giol, Theresa Khalife, Juliette Camuset, Denis Debrosse, Jalal Assouad, Harry Etienne Tags: Full length article Source Type: research

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(Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 18, 2024 Category: OBGYN Source Type: research

The relationship between expression of Tspan5 mRNA in maternal-fetal interface and tubal pregnancy
Tubal pregnancy (TP) is identified as an embryo implantation occurs within the fallopian tube mucosa, with incidence of 1 –2 % worldwide [1,2]. It makes up over 98 % of ectopic pregnancy (EP), which is also the leading cause of maternal morbidity and mortality in the first trimester of pregnancy [3,4]. Although a large number of mechanism studies have been carried out, the exact cause of TP is still unclear [4– 6]. The high-risk factors of TP are usually attributed to tubal surgery [1], endometrial thickness [7], reproductive tract infections (especially genital tract Chlamydia trachomatis infection) [8], smoking [...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 18, 2024 Category: OBGYN Authors: Shiyuan Wei, Tianyang Gao, Yihua Wu, Guiming Wang, Yao Chen, Xinli Tao, Yingqiu Liang, Zijun Zhou, Liyan Sun, Minyin Liu, Haiyan Li, Yanjing Bao Tags: Full length article Source Type: research

Oncologic and reproductive outcomes after fertility-sparing surgery for bilateral borderline ovarian tumors: A retrospective study
Borderline ovarian tumors (BOTs) comprise 10 –20 % of all ovarian malignancies. BOTs show histological properties and biological functions between noncancerous and cancerous epithelial ovarian tumors [1]. Most women with BOTs show significantly higher survival rates [2]. Because BOTs generally occur in teenage girls or young women, fertili ty-sparing surgical treatment that preserves the uterus and at least a part of one ovary has become the gold standard for women with BOTs desiring to preserve their childbearing potential. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 14, 2024 Category: OBGYN Authors: Lili Guo, Xiaoyan Kang, Yue Su, Xiaoyu Liu, Wan Xie, Silu Meng, Yuhuan Liu, Weijiao Wang, Changyu Wang Tags: Full length article Source Type: research

A Systematic Review of Association between use of Hair Products and Benign and Malignant Gynecological conditions
Hair is an integral component of the external covering of most mammals, responsible for creating a physical barrier between an animal and its environment [1]. In humans, although hair has no vital biological function, it has immense psychological importance for both men and women [1,2]. The appearance of hair; especially hair color, length, and style has an impact on people ’s overall self-perception and physical appearance [3]. Unlike most of our physical features, the appearance of our hair can be easily changed without resorting to surgical procedures [4]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 13, 2024 Category: OBGYN Authors: Hajra Farooq, Pauras Mhatre, Riya Aggarwal, Mahalia T. Robinson, Emily Joseph, James Segars, Bhuchitra Singh Tags: Review article Source Type: research

Interventional study to improve pertussis and influenza vaccination uptake in pregnant women
Bordetella pertussis and influenza infections are endemic with intermittent epidemics worldwide. In particular, pertussis is associated with relevant morbidity and mortality in newborns and young infants [1,2]. The incidence of hospitalization due to pertussis in Switzerland was 56.1/100,000 in children under one year of age in 2015 [3]. About a half of the hospitalized children were younger than two months of age. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 13, 2024 Category: OBGYN Authors: Martin Cremer, Siree Kaempfen, Olav Lapaire, Irene Mathilde Hoesli, Ulrich Heininger Tags: Full length article Source Type: research

Preventing postpartum hemorrhage: A network meta-analysis on routes of administration of uterotonics
In 2020, eight hundred women died daily due to pregnancy- and childbirth-related complications, globally [1]. Traditionally, most of these deaths are attributed to excessive bleeding after delivery, known as postpartum hemorrhage (PPH) [2]. The World Health Organization (WHO) defines primary PPH as blood loss of at least 500  mL within the first 24 h after childbirth, whereas secondary PPH can occur even up to 12 weeks postpartum [3]. Indeed, several causes can lead to excessive bleeding after childbirth, but uterine atony is the commonest [2]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 13, 2024 Category: OBGYN Authors: Argyro Papadopoulou, Georgios Tournas, Georgios Georgiopoulos, Panos Antsaklis, Georgios Daskalakis, Arri Coomarasamy, Adam J Devall Tags: Review article Source Type: research

Reproductive outcomes after vaginal repair of isthmocele: A preliminary study and systematic review of the literature
Caesarean section (CS) scar diverticulum, also known as isthmocele, is defined as a pouch-like defect on the anterior wall of the uterine isthmus at the site of a previous caesarean scar [1]. Over the past decade, with the worldwide increase in CS rate, the prevalence of isthmocele has raised varying from 19.4  % to 84 % depending on the study and the diagnostic technique [2]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 13, 2024 Category: OBGYN Authors: Candiani Massimo, Dolci Carolina, Schimberni Matteo, Bartiromo Ludovica, Villanacci Roberta, Grisafi Giorgia, Tandoi Iacopo, Salvatore Stefano, Ferrari Stefano Maria Tags: Review article Source Type: research

Possibility of intrauterine transmission from mother to fetus/newborn: Systematic review and meta-analysis of diagnostic methods to detect SARS-CoV-2 infection
Cronaviruses have appeared for more than 1000  years [1]. The human coronavirus was first isolated in 1965 and recognized in the respiratory tract [2]. Since 2023, at least seven types of coronaviruses have been identified including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), SARS- CoV-1, MERS-CoV, HCoV-OC43, HCoV-229E, HCoV-NL-63, and HCoV-HKU-1 [3]. SARS-CoV-2 is a highly pathogenic and infectious coronavirus that emerged around the end of December 2019. SARS-CoV-2, a single-stranded RNA-positive virus of the Betacoronavirus genus, has caused a deadly pandemic of acute respiratory syndrome known a...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 13, 2024 Category: OBGYN Authors: Pouria Khodavandi, Alireza Khodavandi, Fahimeh Alizadeh, Lida Gholizadeh Tags: Full length article Source Type: research

A comparative study of two pelvimetry methods: 3D models based on CT and MRI
The female pelvis is the pathway through which the fetus is delivered vaginally. Since the 16th century, it has been understood that the shape and size of the pelvis are closely related to the successful completion of labor. In many cases, complex problems arise due to inadequate pelvic size, and research should continue to improve the understanding of this issue and perinatal care to help women in labor give birth safely and naturally and reduce the need for cesarean sections.The primary indications for initial cesarean deliveries often include failure to progress or cephalopelvic disproportion (CPD), accounting for 41.3 ...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 12, 2024 Category: OBGYN Authors: Ping Shen, Jiaxin Fu, Wenling Zhang, Chunlin Chen, Ping Liu Tags: Full length article Source Type: research

Unusual presentation of late-stage ectopic tubal pregnancy (19  weeks’ gestation): Case report and literature review
The implantation of the blastocyst outside of the endometrial cavity is known as ectopic pregnancy [1]. It is a common pregnancy complication that is significant because it accounts for roughly 6  % of all maternal deaths and is the primary cause of death for mothers in the first trimester [1,2,3] The frequency of ectopic pregnancies in our clinic Croatia over the last 5 years is between 0.75 and 1 %. Over 95 % are tubal pregnancies, with 50 % occurring in the ampulla, 20 % in the isth mic region, and the remaining half occurring in the infundibulum, fimbria, or interstitial portion. (Source: European Journal of Obst...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 11, 2024 Category: OBGYN Authors: Danijel Bursa ć, Matilda Zadro, Suzana Haramina, Diana Culej Bošnjak, Neven Tučkar, Krunoslav Kuna Tags: Review article Source Type: research

Unusual presentation of late-stage ectopic tubal pregnancy (19  weeks’ gestation): Case report and literature review
The implantation of the blastocyst outside of the endometrial cavity is known as ectopic pregnancy [1]. It is a common pregnancy complication that is significant because it accounts for roughly 6  % of all maternal deaths and is the primary cause of death for mothers in the first trimester [1,2,3] The frequency of ectopic pregnancies in our clinic Croatia over the last 5 years is between 0.75 and 1 %. Over 95 % are tubal pregnancies, with 50 % occurring in the ampulla, 20 % in th e isthmic region, and the remaining half occurring in the infundibulum, fimbria, or interstitial portion. (Source: European Journal o...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 11, 2024 Category: OBGYN Authors: Danijel Bursa ć, Matilda Zadro, Suzana Haramina, Diana Culej Bošnjak, Neven Tučkar, Krunoslav Kuna Tags: Review article Source Type: research