A randomized, prospective, controlled study comparing uterine preserving laparoscopic lateral suspension with mesh versus laparoscopic sacrohysteropexy in the treatment of uterine prolapse
Pelvic organ prolapse (POP) significantly affects women's quality of life, occurring in 20 –30% of females aged over 20 globally. With aging populations, demand for pelvic reconstructive surgery is rising. Patients seek anatomical restoration while preserving uterus and sexual function. Sacrohysteropexy is the gold standard for apical prolapse, but carries risks. Lateral suspension, off ers safer apical and anterior correction especially for obese, sexually active women. Our prospective study compares laparoscopic sacrohysteropexy and lateral suspension objectively and subjectively. (Source: European Journal of Obstetric...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 7, 2024 Category: OBGYN Authors: Ozan Do ğan, Murat Yassa, Ecem Eren, Pınar Birol İlter, Niyazi Tuğ Tags: Full length article Source Type: research

Surgical evacuation with intraoperative ultrasound (SEE U): A randomised controlled trial
First trimester miscarriage is common affecting 1 in 9 pregnancies [1]. Surgical management of miscarriage (SMM) remains one of the most common surgical procedures with one third of miscarriages managed surgically [2]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 7, 2024 Category: OBGYN Authors: Paul P. Smith, Versha Cheed, Lee Middleton, Adam J. Devall, Firaz Izzat, T. Justin Clark Tags: Full length article Source Type: research

Extended-release versus oral buprenorphine as opioid maintenance treatment during pregnancy-maternal and neonatal outcomes
The prevalence of pregnant individuals with opioid use disorder continues to increase posing health risks to women, fetuses, and children as well as challenges and costs to society [1]. Opioid maintenance treatment during pregnancy is beneficial and widely recommended but carries risks, hence knowledge of the safety profiles of pharmacotherapies is required [2]. Neonates exposed to buprenorphine may experience less severe neonatal opioid withdrawal syndrome than those exposed to methadone [3,4]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 6, 2024 Category: OBGYN Authors: Minna Kanervo, Sarimari Tupola, Eeva Nikkola, Krista Rantakari, Hanna Kahila Tags: Full length article Source Type: research

Prenatal chromosomal microarray analysis and karyotyping in fetuses with isolated choroid plexus cyst: A retrospective case-control study
Choroid plexus cyst (CPC) is a cystic anechoic region in choroid plexus of fetal lateral ventricle. It is one of the common sonographic soft markers in the second trimester, which was first reported by Chudleigh et al. in 1984. Later, Nicolaides et al. pointed out that CPC is related to trisomy 18 [1,2]. In the second trimester, CPC can be found in 1  %-2% of normal fetuses, of which more than 90 % disappear after 28 weeks of gestation and only a few show progressive enlargement [3,4]. CPC is not equivalent to fetal malformation. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 6, 2024 Category: OBGYN Authors: Linlin Wang, Ping Liang, Pingshan Pan, Jiasun Su, Jiayi Qin, Zhaoxia Chen, Dongbing Huang, Weijia Sun, Pengshu Song, Hongwei Wei Tags: Full length article Source Type: research

Immunotherapy combined with targeted therapy in advanced small cell carcinoma of the ovary of hypercalcemic type: A case of overall survival lasting for over 5  years
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a rare but highly aggressive ovarian malignant neoplasm lacking a unified clinical management process. Most patients are diagnosed at an advanced stage and have an extremely poor prognosis with an overall probability of survival less than 10  %. Here, we describe the case of a patient with advanced SCCOHT achieved a survival of over 5 years after receiving multiple cycles of immunotherapy combined with anti-angiogenic therapy or CDK4/6 inhibitors. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 5, 2024 Category: OBGYN Authors: Yi Gao, Li Zang, Yingfei Ye, Fenghua Ma, Mingyi Kang, Kewei Zheng, Yu Kang, Haitao Wang, Congjian Xu Tags: Correspondence Source Type: research

Pelvic floor muscle training patient reported Outcome Measures (PROM) (PFMT-P): Turkish adaptation and its validity and relibiality
Pelvic floor muscles play an important role in supporting the pelvic organs and maintaining urinary and faecal continence [1]. Conditions that cause chronically increased intra-abdominal pressure such as aging, previous pelvic surgery, pregnancy, parity, vaginal birth, obesity, respiratory tract diseases, and constipation and high-effect exercises are risk factors for the development of dysfunction in pelvic floor muscles [2 –6]. Development of dysfunction in pelvic floor muscles negatively affect life quality in approximately 25 % of adult women by leading to a wide range of problems such as urinary and anal incontine...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 3, 2024 Category: OBGYN Authors: Fatma Nil üfer Topkara, Elif Dağlı, Nebahat Özerdoğan Tags: Full length article Source Type: research

Quality of life in long-term cervical cancer survivors compared with healthy women and women with benign gynecological disorders
Cervical cancer survivors (CCSs) experience poorer quality of life (QoL), as well as poorer physical and mental health and social functioning, compared with the general female population [1 –4]. This difference could be due to the existence of more comorbidities than in the general population [1].Data suggest that as the post-treatment follow-up time continues, QoL significantly improves, including physical, cognitive, and emotional functioning [5,6]. Miller et al. [7] and Khalilet a l. [8] have reported no statistically significant differences in the physical well-being between long-term CCSs and women in the general po...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 2, 2024 Category: OBGYN Authors: Jorge Cea Garc ía, Inmaculada Rodríguez Jiménez, Francisco Márquez Maraver, Laura Ríos-Pena, M. Carmen Rubio Rodríguez Tags: Full length article Source Type: research

The great debate: Surgical outcomes of laparoscopic versus laparotomic myomectomy. A meta-analysis to critically evaluate current evidence and look over the horizon
Uterine leiomyomas (UL) are the most common benign pelvic tumors in reproductive aged women [1 –4]. UL can be classified according to International Federation of Gynecology and Obstetrics (FIGO) classification [5–7] as submucosal, intramural, subserosal, or transmural, depending on the location of occurrence: intracavitary, inside the myometrium or in the serosa of the uterus. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 1, 2024 Category: OBGYN Authors: Andrea Giannini, Ilaria Cuccu, Tullio Golia D'Auge, Emanuele De Angelis, Antonio Simone Lagan à, Vito Chiantera, Donatella Caserta, Salvatore Giovanni Vitale, Ludovico Muzii, Ottavia D'Oria, Giorgia Perniola, Giorgio Bogani, Violante Di Donato Tags: Review article Source Type: research

Semi-quantitative metalloproteinase-8 rapid test for the prediction of adverse pregnancy outcomes in patients with preterm premature rupture of membranes
The preterm premature rupture of membranes (preterm PROM) complicates approximately 2  %–3% of pregnancies and precedes one-third of preterm births [1]. Although the exact aetiology remains unclear, intra-amniotic infection/inflammation is critical for preterm PROM; a causal relationship between these two has been identified [2–5]. Traditionally, the intra-amniotic infection/in flammation can be detected by conventional amniotic fluid (AF) analysis via trans-abdominal amniocentesis. Even with enough AF retrieval, microorganism cultivation may take a long time and require laboratory facilities, posing economic and hum...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 31, 2024 Category: OBGYN Authors: Hyeon Ji Kim, Jihyun Choi, Eun Ji Oh, Kyong-No Lee, Jee Yoon Park, Kyung Joon Oh Tags: Full length article Source Type: research

The impact of (very) young donor age on euploid rates: An analysis of 1831 trophectoderm biopsies evaluated with 24-chromosome NGS screening in oocyte donation cycles
Oocyte donation has progressively gained prominence as a technique within assisted reproduction treatments. This trend can be attributed to the advancing age of women seeking pregnancy, resulting in a decline in both the quality and quantity of their own oocytes. “ [1]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 31, 2024 Category: OBGYN Authors: Sonia Albero, Paula Moral, Juan Carlos Castillo, Bel én Lledó, Ruth Morales, José Ortiz, Andrea Bernabeu, Rafael Bernabeu Tags: Full length article Source Type: research

The minimally invasive sacrospinous fixation under visual guidance: An anatomical study
Transvaginal sacrospinous colpopexy is the gold standard procedure for the treatment of vaginal vault prolapse by the vaginal route [1 –4]. The use of Suture Capturing Devices (such as the I Stitch™ device) allows a minimally invasive approach to the sacrospinous ligament (SSL) [5,6]. However, this is a blind technique (no visualization of the ligament); only palpation guides the placement of the suture on this ligament. There are several neurovascular structures closer to the ischial spine (IS), including the inferior gluteal nerve and artery, the internal pudendal artery and the pudendal nerve. (Source: European Jour...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 31, 2024 Category: OBGYN Authors: Gautier Chene, Emanuele Cerruto, Stephanie Moret, Erdogan Nohuz Tags: Full length article Source Type: research

Persistent ischiorectal fistula secondary to rectal extrusion of posterior vaginal mesh: Case report
Reconstructive surgery for pelvic organ prolapse (POP) is performed using native tissues. Vaginal meshes, although they have a lower rate of recurrence of POP, both anatomical and functional, compared to native tissues, have higher rates of reoperation and complications [1]. The average rate of complications of vaginal mesh is around 7 –18 %, the most frequent being extrusion (5–11 %) and dyspareunia (2–3 %)[2]. More than 50 % of women with complications require surgery for their resolution [2]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 31, 2024 Category: OBGYN Authors: Sonia De-Miguel-Manso, Beatriz De-Andres-Asenjo, Julio Gobernado-Tejedor, Elena Garcia-Garc ía, Andrea Vazquez-Fernandez, Cristina Alvarez-Colomo Tags: Review article Source Type: research

Uretrovaginal reflux as a cause of daytime intermitent urinary incontinency in a 14-year old girl
Urethrovaginal reflux (UVR) as a cause of daytime intermittent urinary incontinence (DUI) in girls is an extremely rare clinical phenomenon and rarely described in the literature. A small number of papers on UVR in pediatric age have been published in the PubMed database, some of which I present in the literature [1 –5]. As a contribution to this rare phenomenon, we present a case from our own clinical practice. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 31, 2024 Category: OBGYN Authors: Dubravko Habek Source Type: research

Effect of intraoperative dexmedetomidine on recovery of gastrointestinal function after caesarean section undergoing spinal and epidural anesthesia: A randomized, double blind, placebo-controlled clinical trial
According to the China's National Maternal and Child Health Statistics, the rate of cesarean section in China is significantly higher than the rate recommended by the World Health Organization (46  % vs. 10 ∼ 15 %) [1]. One of the most common complications of cesarean section is postoperative gastrointestinal (GI) dysfunction, which can lead to decreased mobility and thus increase the risk of thrombosis and embolism [2]. The occurrence of postoperative GI dysfunction also has been a ssociated with longer hospital stays and increased healthcare costs, especially when the dysfunction encompasses prolonged ileus. (S...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 29, 2024 Category: OBGYN Authors: Jing-jing Sun, Huan Wang, Li-li Tang, Hui Jiang, Xue-sheng Liu Tags: Full length article Source Type: research

Malathion exposure may increase infertility risk among US Adults: Results from the 2015 –2016 NHANES
Organophosphate pesticides such as malathion are the most widely used pesticides. Despite endocrine-disrupting effects, there is a paucity of information regarding chronic exposure to non-persistent organopesticides such as malathion. The purpose of this study is to describe the exposure burden among U.S. residents as well as possible impacts on fertility. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 27, 2024 Category: OBGYN Authors: Samantha R. Streich, Thomas A. Beltran, Bruce D. Pier Tags: Full length article Source Type: research