Quality of life in long-term cervical cancer survivors compared with healthy women and women with benign gynecological disorders
Cervical cancer survivors (CCSs) experience poorer quality of life (QoL), as well as poorer physical and mental health and social functioning, compared with the general female population [1 –4]. This difference could be due to the existence of more comorbidities than in the general population [1].Data suggest that as the post-treatment follow-up time continues, QoL significantly improves, including physical, cognitive, and emotional functioning [5,6]. Miller et al. [7] and Khalilet a l. [8] have reported no statistically significant differences in the physical well-being between long-term CCSs and women in the general po...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 2, 2024 Category: OBGYN Authors: Jorge Cea Garc ía, Inmaculada Rodríguez Jiménez, Francisco Márquez Maraver, Laura Ríos-Pena, M. Carmen Rubio Rodríguez Tags: Full length article Source Type: research

The great debate: Surgical outcomes of laparoscopic versus laparotomic myomectomy. A meta-analysis to critically evaluate current evidence and look over the horizon
Uterine leiomyomas (UL) are the most common benign pelvic tumors in reproductive aged women [1 –4]. UL can be classified according to International Federation of Gynecology and Obstetrics (FIGO) classification [5–7] as submucosal, intramural, subserosal, or transmural, depending on the location of occurrence: intracavitary, inside the myometrium or in the serosa of the uterus. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 1, 2024 Category: OBGYN Authors: Andrea Giannini, Ilaria Cuccu, Tullio Golia D'Auge, Emanuele De Angelis, Antonio Simone Lagan à, Vito Chiantera, Donatella Caserta, Salvatore Giovanni Vitale, Ludovico Muzii, Ottavia D'Oria, Giorgia Perniola, Giorgio Bogani, Violante Di Donato Tags: Review article Source Type: research

Semi-quantitative metalloproteinase-8 rapid test for the prediction of adverse pregnancy outcomes in patients with preterm premature rupture of membranes
The preterm premature rupture of membranes (preterm PROM) complicates approximately 2  %–3% of pregnancies and precedes one-third of preterm births [1]. Although the exact aetiology remains unclear, intra-amniotic infection/inflammation is critical for preterm PROM; a causal relationship between these two has been identified [2–5]. Traditionally, the intra-amniotic infection/in flammation can be detected by conventional amniotic fluid (AF) analysis via trans-abdominal amniocentesis. Even with enough AF retrieval, microorganism cultivation may take a long time and require laboratory facilities, posing economic and hum...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 31, 2024 Category: OBGYN Authors: Hyeon Ji Kim, Jihyun Choi, Eun Ji Oh, Kyong-No Lee, Jee Yoon Park, Kyung Joon Oh Tags: Full length article Source Type: research

The impact of (very) young donor age on euploid rates: An analysis of 1831 trophectoderm biopsies evaluated with 24-chromosome NGS screening in oocyte donation cycles
Oocyte donation has progressively gained prominence as a technique within assisted reproduction treatments. This trend can be attributed to the advancing age of women seeking pregnancy, resulting in a decline in both the quality and quantity of their own oocytes. “ [1]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 31, 2024 Category: OBGYN Authors: Sonia Albero, Paula Moral, Juan Carlos Castillo, Bel én Lledó, Ruth Morales, José Ortiz, Andrea Bernabeu, Rafael Bernabeu Tags: Full length article Source Type: research

The minimally invasive sacrospinous fixation under visual guidance: An anatomical study
Transvaginal sacrospinous colpopexy is the gold standard procedure for the treatment of vaginal vault prolapse by the vaginal route [1 –4]. The use of Suture Capturing Devices (such as the I Stitch™ device) allows a minimally invasive approach to the sacrospinous ligament (SSL) [5,6]. However, this is a blind technique (no visualization of the ligament); only palpation guides the placement of the suture on this ligament. There are several neurovascular structures closer to the ischial spine (IS), including the inferior gluteal nerve and artery, the internal pudendal artery and the pudendal nerve. (Source: European Jour...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 31, 2024 Category: OBGYN Authors: Gautier Chene, Emanuele Cerruto, Stephanie Moret, Erdogan Nohuz Tags: Full length article Source Type: research

Persistent ischiorectal fistula secondary to rectal extrusion of posterior vaginal mesh: Case report
Reconstructive surgery for pelvic organ prolapse (POP) is performed using native tissues. Vaginal meshes, although they have a lower rate of recurrence of POP, both anatomical and functional, compared to native tissues, have higher rates of reoperation and complications [1]. The average rate of complications of vaginal mesh is around 7 –18 %, the most frequent being extrusion (5–11 %) and dyspareunia (2–3 %)[2]. More than 50 % of women with complications require surgery for their resolution [2]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 31, 2024 Category: OBGYN Authors: Sonia De-Miguel-Manso, Beatriz De-Andres-Asenjo, Julio Gobernado-Tejedor, Elena Garcia-Garc ía, Andrea Vazquez-Fernandez, Cristina Alvarez-Colomo Tags: Review article Source Type: research

Uretrovaginal reflux as a cause of daytime intermitent urinary incontinency in a 14-year old girl
Urethrovaginal reflux (UVR) as a cause of daytime intermittent urinary incontinence (DUI) in girls is an extremely rare clinical phenomenon and rarely described in the literature. A small number of papers on UVR in pediatric age have been published in the PubMed database, some of which I present in the literature [1 –5]. As a contribution to this rare phenomenon, we present a case from our own clinical practice. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 31, 2024 Category: OBGYN Authors: Dubravko Habek Source Type: research

Effect of intraoperative dexmedetomidine on recovery of gastrointestinal function after caesarean section undergoing spinal and epidural anesthesia: A randomized, double blind, placebo-controlled clinical trial
According to the China's National Maternal and Child Health Statistics, the rate of cesarean section in China is significantly higher than the rate recommended by the World Health Organization (46  % vs. 10 ∼ 15 %) [1]. One of the most common complications of cesarean section is postoperative gastrointestinal (GI) dysfunction, which can lead to decreased mobility and thus increase the risk of thrombosis and embolism [2]. The occurrence of postoperative GI dysfunction also has been a ssociated with longer hospital stays and increased healthcare costs, especially when the dysfunction encompasses prolonged ileus. (S...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 29, 2024 Category: OBGYN Authors: Jing-jing Sun, Huan Wang, Li-li Tang, Hui Jiang, Xue-sheng Liu Tags: Full length article Source Type: research

Malathion exposure may increase infertility risk among US Adults: Results from the 2015 –2016 NHANES
Organophosphate pesticides such as malathion are the most widely used pesticides. Despite endocrine-disrupting effects, there is a paucity of information regarding chronic exposure to non-persistent organopesticides such as malathion. The purpose of this study is to describe the exposure burden among U.S. residents as well as possible impacts on fertility. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 27, 2024 Category: OBGYN Authors: Samantha R. Streich, Thomas A. Beltran, Bruce D. Pier Tags: Full length article Source Type: research

Efficacy and safety of dienogest in the treatment of deep infiltrating endometriosis: A meta-analysis
Deep infiltrating endometriosis (DIE) refers to endometriosis (EMs) with an infiltration depth greater than or equal to 5  mm. It is an invasive disease that involves the uterosacral ligament, the excavatio rectouterina, vaginal vault, vaginal-rectal septum, rectum, colon wall, bladder wall, and the ureter. DIE can cause evident chronic pelvic pain, dysmenorrhea, dyspareunia, dysuria, non-menstrual pelvic pain, local bleeding, and the obstruction of vital organs. EMs affects about 10 % of women of childbearing age. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 27, 2024 Category: OBGYN Authors: Han Wu, Jun-Jiang Liu, Sheng-Tou Ye, Jun Liu, Na Li Tags: Review article Source Type: research

Physical activity among pregnant inpatients and outpatients and associations with anxiety
Anxiety and depression are prevalent among hospitalized pregnant people [1]. Despite this, little is known regarding ways to improve their mental health. Given the rising public health threat posed by mental illness [2], identification of feasible, realistic interventions to improve mental health is critically warranted. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 27, 2024 Category: OBGYN Authors: Danielle M. Panelli, Hayley E. Miller, Samantha L. Simpson, Janet Hurtado, Chi-Hung Shu, Ana C. Boncompagni, Jane Chueh, Brendan Carvalho, Pervez Sultan, Nima Aghaeepour, Maurice L. Druzin Tags: Full length article Source Type: research

Relationship between serum apelin, visfatin levels, and body composition in Polycystic ovary syndrome patients
Polycystic ovary syndrome (PCOS) is an endocrine disorder that affects the female reproductive system. It is characterized by irregular ovulation, high levels of androgens, and multiple cysts on the ovaries. PCOS is a common condition among women of reproductive age [1]. Epidemiological findings indicate that the incidence of PCOS ranges from 3.7  % to 22.5 % [2]. The prevalence of PCOS in Chinese women is 7.8 %, affecting the reproductive health of approximately 24 million women [3]. In addition, PCOS is a systemic metabolic disorder that is often associated with obesity, insulin resistance, metabolic disorders, and...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 27, 2024 Category: OBGYN Authors: Dan Kuai, Qingtao Tang, Xiang wang, Qi Yan, Wenyan Tian, Huiying Zhang Tags: Full length article Source Type: research

Miscarriage and stillbirth in relation to risk of cardiovascular diseases: A systematic review and meta-analysis
The relationship between pregnancy loss and the risk of cardiovascular diseases (CVDs) remains a matter of debate. Our intention in conducting this meta-analysis was to analyze the relationship between miscarriage and stillbirth and risk of CVDs. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 27, 2024 Category: OBGYN Authors: Mengmeng Wang, Jinli Zhang, Lijun Yuan, Huifang Hu, Tianze Li, Yifei Feng, Yang Zhao, Yuying Wu, Xueru Fu, Yamin Ke, Yajuan Gao, Yaobing Chen, Weifeng Huo, Longkang Wang, Wenkai Zhang, Xi Li, Jiong Liu, Zelin Huang, Fulan Hu, Ming Zhang, Liang Sun, Dongsh Tags: Review article Source Type: research

Construction and efficacy test of a survival prediction model for locally advanced cervical cancer based on anti-angiogenesis
Cervical cancer (CC) is a major global threat to women ’s health, with about 500,000 new cases and 200,000 deaths each year [1]. Patients with metastatic or recurrent CC have a poor prognosis, and only 10 % of those with locally advanced CC survive for five years [2]. Hence, a reliable survival prediction model is needed to estimate the prognosis of advanced patients before treatment and offer personalized care to low responders to improve their survival. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 27, 2024 Category: OBGYN Authors: Yuanyuan luo, Xiaojie ma Tags: Full length article Source Type: research

Plasma and peritoneal fluid cytokine profiles in patient with Essure ® implant: Towards a molecular signature?
The Essure ® contraceptive device (Bayer©, Leverkusen, Germany) was the first permanent tubal occlusion hysteroscopic implant approved by the FDA in 2002 and definitively stopped in 2018 after 750,000 procedures worldwide [1]. Many patients described adverse events, including pelvic pain, as well as general clinical symptoms such as fatigue, hair loss, psychological disorders, loss of libido, pain in joints, weight changes, and lack of concentration [2–5]. The pathogenesis is not yet understood. Several hypotheses have been proposed, such as the Systemic Nickel Allergic Syndrome (SNAS) [6,7], the Aut oimmune/Autoinflam...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - March 25, 2024 Category: OBGYN Authors: Lorna Garnier, Fran çois Parant, Claire Bulteau, Remi Pescarmona, Emanuele Cerruto, Stephanie Moret, Chloe Miguet-Bensouda, Erdogan Nohuz, Gautier Chene Tags: Full length article Source Type: research