Timing of administration of antenatal magnesium sulphate and correlation with umbilical cord blood magnesium levels in preterm babies

Preterm brain damage is still a significant and unresolved problem for neonatologists. Periventricular leukomalacia, intraventricular/intraparenchymal hemorrhage and white matter damage are among the cerebral abnormalities that follow encephalopathy of prematurity and are significantly linked to subsequent cerebral palsy and neurobehavioral developmental issues. These types of brain damage can occur for a variety of reasons, such as inflammation or ischemia assault. There could be a number of risk factors which exist during, before and after birth (e.g., extra and inta-uterine growth restriction, perinatal hypoxia –ischemia or systemic inflammation,).
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Full length article Source Type: research