Trauma diagnostic-related target proteins and their detection techniques - Wei YL, Ren X, Yuan Z, Hong J, Wang T, Chen W, Xu Y, Ding J, Lin J, Jiang W, Zhang P, Wu Q.
Trauma is a significant health issue that not only leads to immediate death in many cases but also causes severe complications, such as sepsis, thrombosis, haemorrhage, acute respiratory distress syndrome and traumatic brain injury, among trauma patients. ... (Source: SafetyLit)
Source: SafetyLit - April 15, 2024 Category: International Medicine & Public Health Tags: Environmental Issues, Climate, Geophysics Source Type: news
Subarachnoid hemorrhage confirmed by magnetic resonance imaging in a patient with brain death owing to hypoxic encephalopathy following suicide by hanging - Oshida S, Yokosawa T, Araya S, Sato S, Suzuki T, Akamatsu Y, Ogasawara K.
Although true subarachnoid hemorrhage (SAH) is an atypical complication owing to suicide by hanging, pseudo-SAH can often develop because of hypoxic encephalopathy. Therefore, differentiating pseudo-SAH from true SAH using brain computed tomography (CT) is... (Source: SafetyLit)
Source: SafetyLit - April 11, 2024 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Roche and Alnylam present positive results from the Phase II KARDIA-2 study of zilebesiran added to standard of care antihypertensives in patients with inadequately controlled hypertension
The KARDIA-2 study met its primary endpoint demonstrating additive, placebo-adjusted systolic blood pressure reductions of up to 12.1 mmHgat month three. These results were statistically significant and clinically meaningfulZilebesiran demonstrated an encouraging safety and tolerability profile when added to standard of care antihypertensives Basel, 7 April 2024 - Roche (SIX: RO, ROG; OTCQX: RHHBY) and Alnylam today released detailed results from the Phase II KARDIA-2 study evaluating the efficacy and safety of a single subcutaneous dose of zilebesiran when added to one of three standard of care (SOC) antihypertensives. T...
Source: Roche Investor Update - April 7, 2024 Category: Pharmaceuticals Source Type: news
"NeuroVanguard": a contemporary strategy in neuromonitoring for severe adult brain injury patients - Rodriguez EE, Zaccarelli M, Sterchele ED, Taccone FS.
Severe acute brain injuries, stemming from trauma, ischemia or hemorrhage, remain a significant global healthcare concern due to their association with high morbidity and mortality rates. Accurate assessment of secondary brain injuries severity is pivotal ... (Source: SafetyLit)
Source: SafetyLit - April 4, 2024 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Hemorrhagic Stroke a Key Driver of Spike in US Stroke Rates Hemorrhagic Stroke a Key Driver of Spike in US Stroke Rates
Absolute stroke rates have increased in recent years, with hemorrhagic stroke showing the most striking increase in mortality, new data show.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - March 26, 2024 Category: Cardiology Tags: Neurology & Neurosurgery Source Type: news
Massive intracerebral hemorrhage following methamphetamine poisoning in a man: a case report - Banimostafavi ES, Taheri A, Malakian A, Zakariaei Z.
INTRODUCTION AND IMPORTANCE: Methamphetamine (MAP) is a highly addictive stimulant known to have detrimental effects on the brain and various physiological systems, including an elevation in heart rate and blood pressure. Additionally, MAP use has been lin... (Source: SafetyLit)
Source: SafetyLit - March 25, 2024 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Clinical characteristics associated with pediatric traumatic intracranial hemorrhage - Tanaanantarak P, Suntornsawat S, Samphao S.
PURPOSE: Traumatic brain injury (TBI) can cause significant morbidity and mortality in the pediatric population. Brain CT is the mainstay in the diagnosis of intracranial hemorrhage (ICH). The aim of this study was to explore the clinical characteristics t... (Source: SafetyLit)
Source: SafetyLit - March 18, 2024 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Tenecteplase Effective for Stroke in Later Time Window Tenecteplase Effective for Stroke in Later Time Window
Patients treated with tenecteplase at up to 24 hours had a threefold higher rate of reperfusion without intracranial hemorrhage than those receiving best medical treatment.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - March 11, 2024 Category: Cardiology Tags: Neurology & Neurosurgery Source Type: news
Overall Stroke Rates Down, but Hemorrhagic Stroke Up in Recent Years
MONDAY, March 11, 2024 -- Age-standardized stroke rates mostly declined from 1990 to 2019, with the exception of hemorrhagic stroke, the rates of which increased, according to a study published online March 4 in JAMA Neurology.
Daniela Renedo,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 11, 2024 Category: Pharmaceuticals Source Type: news
Roche and Alnylam report positive topline results from the Phase II KARDIA-2 study in people with hypertension, demonstrating clinically significant blood pressure reductions with zilebesiran when added to standard of care
KARDIA-2 study met its primary endpoint, demonstrating clinically significant systolic blood pressure reductions in each treatment arm at month threeZilebesiran added to a standard of care hypertension medication demonstrated an encouraging safety and tolerability profile in adults with mild to moderate uncontrolled hypertension, and results support the potential for twice-yearly dosingRoche and Alnylam have initiated the Phase II KARDIA-3 study in adults with uncontrolled hypertension at high cardiovascular riskKARDIA-2 study results will be presented as a late-breaking abstract in April at the 2024 American College of Ca...
Source: Roche Investor Update - March 5, 2024 Category: Pharmaceuticals Source Type: news
Roche and Alnylam report positive topline results from the Phase II KARDIA-2 study in people with hypertension, demonstrating clinically significant blood pressure reductions with zilebesiran when added to standard of care
KARDIA-2 study met its primary endpoint, demonstrating clinically significant systolic blood pressure reductions in each treatment arm at month threeZilebesiran added to a standard of care hypertension medication demonstrated an encouraging safety and tolerability profile in adults with mild to moderate uncontrolled hypertension, and results support the potential for twice-yearly dosingRoche and Alnylam have initiated the Phase II KARDIA-3 study in adults with uncontrolled hypertension at high cardiovascular riskKARDIA-2 study results will be presented as a late-breaking abstract in April at the 2024 American College of Ca...
Source: Roche Media News - March 5, 2024 Category: Pharmaceuticals Source Type: news
Impact of triage systems on time to diagnosis and treatment of traumatic brain injuries - Nwizu M, Weiner T, Downs T, Krizo J, Mangira C, Cowan S, Mallat A, Heaney A.
BACKGROUND: Intracerebral hemorrhage (ICH) is a potential complication from traumatic brain injury, with a 30-day mortality rate of 35-52%. Rapid diagnosis allows for earlier treatment, which impacts patient outcomes. A trauma activation (TA) is called whe... (Source: SafetyLit)
Source: SafetyLit - March 4, 2024 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
What Are the Health Problems for Off-Spring of Mothers with Pre-eclampsia?
Discussion
“Pre-eclampsia is a complex multisystem disease, diagnosed by sudden-onset hypertension (> 20 weeks of gestation) and at least one other associated complication, including proteinuria, maternal organ dysfunction or uteroplacental dysfunction…[It] is one of the most severe complications of pregnancy and a leading causes of maternal and perinatal morbidity and mortality.” Deaths per year world wide are estimated to be 500,000 babies and > 70,000 women. Women that survive have decreased life-expectancy and it is estimated that > 300 million women and children are at “…increase...
Source: PediatricEducation.org - March 4, 2024 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Reversing Anticoagulation in Hemorrhagic Stroke; E-Cigs for Smoking Cessation
(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - February 18, 2024 Category: Cardiology Source Type: news
Faster brain hemorrhage treatment increases survival odds, new study finds
While a treatment timing paradigm exists for strokes caused by clotting, researchers show that quicker treatment for brain bleeding can also make a difference. (Source: Yale Science and Health News)
Source: Yale Science and Health News - February 13, 2024 Category: Universities & Medical Training Source Type: news
