Clinical characteristics associated with pediatric traumatic intracranial hemorrhage - Tanaanantarak P, Suntornsawat S, Samphao S.
PURPOSE: Traumatic brain injury (TBI) can cause significant morbidity and mortality in the pediatric population. Brain CT is the mainstay in the diagnosis of intracranial hemorrhage (ICH). The aim of this study was to explore the clinical characteristics t... (Source: SafetyLit)
Source: SafetyLit - March 18, 2024 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Tenecteplase Effective for Stroke in Later Time Window Tenecteplase Effective for Stroke in Later Time Window
Patients treated with tenecteplase at up to 24 hours had a threefold higher rate of reperfusion without intracranial hemorrhage than those receiving best medical treatment.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - March 11, 2024 Category: Cardiology Tags: Neurology & Neurosurgery Source Type: news

Overall Stroke Rates Down, but Hemorrhagic Stroke Up in Recent Years
MONDAY, March 11, 2024 -- Age-standardized stroke rates mostly declined from 1990 to 2019, with the exception of hemorrhagic stroke, the rates of which increased, according to a study published online March 4 in JAMA Neurology. Daniela Renedo,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 11, 2024 Category: Pharmaceuticals Source Type: news

Roche and Alnylam report positive topline results from the Phase II KARDIA-2 study in people with hypertension, demonstrating clinically significant blood pressure reductions with zilebesiran when added to standard of care
KARDIA-2 study met its primary endpoint, demonstrating clinically significant systolic blood pressure reductions in each treatment arm at month threeZilebesiran added to a standard of care hypertension medication demonstrated an encouraging safety and tolerability profile in adults with mild to moderate uncontrolled hypertension, and results support the potential for twice-yearly dosingRoche and Alnylam have initiated the Phase II KARDIA-3 study in adults with uncontrolled hypertension at high cardiovascular riskKARDIA-2 study results will be presented as a late-breaking abstract in April at the 2024 American College of Ca...
Source: Roche Investor Update - March 5, 2024 Category: Pharmaceuticals Source Type: news

Roche and Alnylam report positive topline results from the Phase II KARDIA-2 study in people with hypertension, demonstrating clinically significant blood pressure reductions with zilebesiran when added to standard of care
KARDIA-2 study met its primary endpoint, demonstrating clinically significant systolic blood pressure reductions in each treatment arm at month threeZilebesiran added to a standard of care hypertension medication demonstrated an encouraging safety and tolerability profile in adults with mild to moderate uncontrolled hypertension, and results support the potential for twice-yearly dosingRoche and Alnylam have initiated the Phase II KARDIA-3 study in adults with uncontrolled hypertension at high cardiovascular riskKARDIA-2 study results will be presented as a late-breaking abstract in April at the 2024 American College of Ca...
Source: Roche Media News - March 5, 2024 Category: Pharmaceuticals Source Type: news

Impact of triage systems on time to diagnosis and treatment of traumatic brain injuries - Nwizu M, Weiner T, Downs T, Krizo J, Mangira C, Cowan S, Mallat A, Heaney A.
BACKGROUND: Intracerebral hemorrhage (ICH) is a potential complication from traumatic brain injury, with a 30-day mortality rate of 35-52%. Rapid diagnosis allows for earlier treatment, which impacts patient outcomes. A trauma activation (TA) is called whe... (Source: SafetyLit)
Source: SafetyLit - March 4, 2024 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

What Are the Health Problems for Off-Spring of Mothers with Pre-eclampsia?
Discussion “Pre-eclampsia is a complex multisystem disease, diagnosed by sudden-onset hypertension (> 20 weeks of gestation) and at least one other associated complication, including proteinuria, maternal organ dysfunction or uteroplacental dysfunction…[It] is one of the most severe complications of pregnancy and a leading causes of maternal and perinatal morbidity and mortality.” Deaths per year world wide are estimated to be 500,000 babies and > 70,000 women. Women that survive have decreased life-expectancy and it is estimated that > 300 million women and children are at “…increase...
Source: PediatricEducation.org - March 4, 2024 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Reversing Anticoagulation in Hemorrhagic Stroke; E-Cigs for Smoking Cessation
(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - February 18, 2024 Category: Cardiology Source Type: news

Faster brain hemorrhage treatment increases survival odds, new study finds
While a treatment timing paradigm exists for strokes caused by clotting, researchers show that quicker treatment for brain bleeding can also make a difference. (Source: Yale Science and Health News)
Source: Yale Science and Health News - February 13, 2024 Category: Universities & Medical Training Source Type: news

EVT appears underused in certain stroke patients
In this study, patients hospitalized with ischemic stroke and cardiac intervention may be less than half as likely to receive EVT as those without cardiac intervention,” the group wrote. Ultimately, the lower rates of EVT after cardiac intervention seen in the study could be explained by multiple factors: delays in diagnosis, clinician reluctance due to perceived higher procedural risk, or patients being ineligible, the researchers suggested. They noted that additional studies are needed to explore these issues. “Given the known benefit of EVT, there is a need to better understand the reasons for lower rates of EVT ...
Source: AuntMinnie.com Headlines - January 30, 2024 Category: Radiology Authors: Will Morton Tags: Subspecialties Cardiovascular Radiology Neuroradiology Source Type: news

Spontaneous bilateral basal ganglia haemorrhage secondary to methanol poisoning - Sohor NJ, Loh WC, Pang RY, Khan AH, Chia PK, Sulaiman WAW, Mat LI, Hoo FK, Basri H.
Methanol toxicity remains as major problem in the medical field.([1],[2],[3]) With its active metabolite, formic acid often leads to severe metabolic acidosis and to some extend brain damaged.([4],[5],[6]) We are reporting a case of brain hemorrhage at the... (Source: SafetyLit)
Source: SafetyLit - January 8, 2024 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Nuclear Tracer Shortage; Weighing Post-Ablation OAC; Fix for Biased AI Tools?
(MedPage Today) -- Magnesium's hemostatic effects in intracerebral hemorrhage were supported by reduced hematoma expansion in FAST-MAG participants who achieved higher serum magnesium levels with magnesium treatment. (Stroke) The American Society... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - December 27, 2023 Category: Cardiology Source Type: news

Nuance and profound impact: evaluating the effects of the unmet full coma scale in patients with mild subdural hemorrhage - Chien SC, Kang SC, Tu PH, Chen CC, Tee YS, Liao CH, Chuang CC, Fu CY.
INTRODUCTION: Patients with subdural hemorrhage (SDH) and a Glasgow Coma Scale (GCS) score of 13-15 are typically categorized as having mild traumatic brain injury. We hypothesize that patients without a maximum GCS score - specifically, patients with GCS ... (Source: SafetyLit)
Source: SafetyLit - December 18, 2023 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Science ’s 2023 Breakthrough of the Year: Weight loss drugs with a real shot at fighting obesity
Show / hide sections navigation 2023 Breakthrough of the Year Runners-up Breakdowns Video Obesity plays out as a private struggle and a public health crisis. In the United States, about 70% of adults are affected by excess weight, and in Europe that number is more than half. The stigma against fat can be crushing; its risks, life-threatening. Defined as a body mass index of at least 30, obesity is thought to power type 2 diabetes, heart disease, arthritis, fatty liver disease, and certain cancers. Yet drug treatments...
Source: ScienceNOW - December 14, 2023 Category: Science Source Type: news

Interventional treatment of symptomatic vasospasm in the setting of traumatic brain injury; a systematic review of published cases - Sorrentino ZA, Lucke-Wold BP, Laurent D, Quintin SS, Hoh BL.
Traumatic subarachnoid hemorrhage (tSAH) is frequently co-morbid with traumatic brain injury (TBI), and may induce secondary injury through vascular changes such as vasospasm and subsequent delayed cerebral ischemia (DCI). While aneurysmal SAH is well stud... (Source: SafetyLit)
Source: SafetyLit - December 5, 2023 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news