UCLA study shows promise, offers hope for brain hemorrhage patients
A new endoscopic surgical procedure has been shown to be safer and to result in better outcomes than the current standard medical treatment for patients who suffer strokes as a result of brain hemorrhages, UCLA neurosurgeons have announced.   The findings from their potentially groundbreaking, randomized, controlled phase 2 clinical trial, which was conducted at multiple medical centers, were presented last week at the International Stroke Conference in Honolulu.   "These exciting results offer a glimmer of hope for a condition that most doctors have traditionally considered hopeless," said principal in...
Source: UCLA Newsroom: Health Sciences - February 11, 2013 Category: Universities & Medical Training Source Type: news

Improved Outcomes After Bleeding Stroke For Patients Who Undergo Surgical Procedure
A minimally invasive procedure to remove blood clots in brain tissue after hemorrhagic stroke appears safe and may also reduce long-term disability, according to late-breaking research presented at the American Stroke Association's International Stroke Conference 2013. Of the hundreds of thousands of Americans who have intracerebral hemorrhages (ICH) each year, most are severely debilitated, said Daniel Hanley, M.D., lead author and professor of neurology at Johns Hopkins School of Medicine in Baltimore, Md. ICH is the most common type of bleeding stroke... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 11, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

Better Results After Stroke Than Supportive Therapy Alone Afforded By Treatment With Clot-Busting Drug
In an update to previous research, Johns Hopkins neurologists say minimally invasive delivery of the drug tPA directly into potentially lethal blood clots in the brain helped more patients function independently a year after suffering an intracerebral hemorrhage (ICH), a deadly and debilitating form of stroke. Rates of functional recovery with the active tPA treatment far surpassed those achieved with standard "supportive" therapy that essentially gives clots a chance to shrink on their own... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 11, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

Survivors Of Stroke In Infancy Prone To Seizures, Epilepsy
About one-third of American infants and children who suffer bleeding into brain tissue, may later have seizures and as many as 13 percent will develop epilepsy within two years, according to new research reported at the American Stroke Association's International Stroke Conference 2013. Bleeding into brain tissue is a type of stroke called intracerebral hemorrhage (ICH). Each year, an estimated 6.4 newborns and children per every 100,000 in the United States suffer strokes. About half of the strokes are hemorrhagic, typically caused by rupturing of weakened or malformed blood vessels... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 11, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

Child Stroke Survivors Prone to Seizures
(Ivanhoe Newswire) -- Bleeding into brain tissue is a type of stroke called intracerebral hemorrhage (ICH). Each year, an estimated 6.4 newborns and children per every 100,000 in the United States suffer strokes. About half of the strokes are hemorrhagic, typically caused by rupturing of weakened or malformed blood vessels. (Source: Medical Headlines From Ivanhoe.com)
Source: Medical Headlines From Ivanhoe.com - February 11, 2013 Category: Consumer Health News Source Type: news

Bleeding Strokes Occur At Earlier Age, Independent Of Meth Use, In Native Hawaiians
Native Hawaiians and Pacific Islanders have more bleeding strokes at an earlier age than other people independent of methamphetamine abuse, according to research presented at the American Stroke Association's International Stroke Conference 2013. "Drug abuse is a huge problem here and it definitely is a cause of hemorrhagic stroke," said Kazuma Nakagawa, M.D., lead investigator and assistant professor of medicine at the University of Hawaii. "But Native Hawaiians and Pacific Islanders are experiencing this form of stroke at a younger age even without methamphetamine use... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 8, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

New brain 'injection' treatment gives hope to 20,000 stroke sufferers
Technique of inserting drugs in the brain could help thousands of patients who suffer a bleeding stroke, or brain haemorrhage, for which there is currently no surgical treatment. (Source: the Mail online | Health)
Source: the Mail online | Health - February 8, 2013 Category: Consumer Health News Source Type: news

Seizures Common in Pediatric Stroke (CME/CE)
(MedPage Today) -- Almost half of children with hemorrhagic stroke had seizures at presentation or within a week of onset, but two-thirds had no further seizures 2 years later, a prospective study showed. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - February 7, 2013 Category: Cardiology Source Type: news

Cocaine-Induced Stroke Often Deadly (CME/CE)
HONOLULU (MedPage Today) -- Among patients with an aneurysmal subarachnoid hemorrhage, recent cocaine use was associated with a greater chance of dying in the hospital, researchers found. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - February 7, 2013 Category: Cardiology Source Type: news

Brain Bleeds Linked to Race (CME/CE)
HONOLULU (MedPage Today) -- The high rate of intracerebral hemorrhage among young Native Hawaiians and other Pacific Islanders appears to be related to race, researchers suggested. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - February 7, 2013 Category: Cardiology Source Type: news

Active Treatment with Clot-Busting Drug Yields Better Results after Stroke than Supportive Therapy Alone - 2/7/13
In an update to previous research, Johns Hopkins neurologists say minimally invasive delivery of the drug tPA directly into potentially lethal blood clots in the brain helped more patients function independently a year after suffering an intracerebral hemorrhage (ICH). (Source: Johns Hopkins Medicine News)
Source: Johns Hopkins Medicine News - February 7, 2013 Category: Research Source Type: news

Treatment with clot-busting drug yields better results after stroke than supportive therapy alone
(Johns Hopkins Medicine) In an update to previous research, Johns Hopkins neurologists say minimally invasive delivery of the drug tPA directly into potentially lethal blood clots in the brain helped more patients function independently a year after suffering an intracerebral hemorrhage, a deadly and debilitating form of stroke. Rates of functional recovery with the active tPA treatment far surpassed those achieved with standard "supportive" therapy that essentially gives clots a chance to shrink on their own. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 7, 2013 Category: Global & Universal Source Type: news

Woman trapped in her own body for nine months after brain haemorrhage makes startling recovery thanks to last ditch surgery
Pauline Quinn, 49, from Chesterfield, couldn't walk, talk or feed herself after suffering a brain haemorrhage in July 2011. (Source: the Mail online | Health)
Source: the Mail online | Health - February 4, 2013 Category: Consumer Health News Source Type: news

New Control On Blood Vessels In Developing Brain Revealed By Chance Finding
Zhen Huang freely admits he was not interested in blood vessels four years ago when he was studying brain development in a fetal mouse. Instead, he wanted to see how changing a particular gene in brain cells called glia would affect the growth of neurons. The result was hemorrhage, caused by deteriorating veins and arteries, and it begged for explanation. "It was a surprising finding," says Huang, an assistant professor of neuroscience and neurology at the University of Wisconsin-Madison... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 29, 2013 Category: Consumer Health News Tags: Neurology / Neuroscience Source Type: news

Does smoking marijuana cause stroke?
1.5 out of 5 stars Cannabis-related Stroke: Myth or Reality? Wolff V et al. Stroke 2013 Feb;44(2):558-63. doi: 10.1161/STROKEAHA.112.671347. Epub 2012 Dec 27. No abstract available There have been scattered reports in the literature claiming an association between the use of cannabis and ischemia and/or hemorrhagic stroke. Although no convincing mechanism has been postulated, some suggest that use of marijuana or hashish and the occurrence of stroke may stem from the ability of cannabis to cause orthostatic hypotension, or possibly vasoconstriction. If such an association is real, it must be exceedingly rare. The...
Source: The Poison Review - January 27, 2013 Category: Toxicology Authors: Leon Tags: Medical cannabis cerebral vascular accident hashish marijuana neurotoxicity stroke Source Type: news

Chance finding reveals new control on blood vessels in developing brain
Zhen Huang freely admits he was not interested in blood vessels four years ago when he was studying brain development in a fetal mouse. Instead, he wanted to see how changing a particular gene in brain cells called glia would affect the growth of neurons. The result was hemorrhage, caused by deteriorating veins and arteries, and it begged for explanation. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 24, 2013 Category: Science Source Type: news

Chance finding reveals new control on blood vessels in developing brain
(University of Wisconsin-Madison) Zhen Huang freely admits he was not interested in blood vessels four years ago when he was studying brain development in a fetal mouse. Instead, he wanted to see how changing a particular gene in brain cells called glia would affect the growth of neurons. The result was hemorrhage, caused by deteriorating veins and arteries, and it begged for explanation. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 24, 2013 Category: Global & Universal Source Type: news

Mother, 27, dies from brain haemorrhage after giving birth to seventh child
Emma Butterfield (pictured) of Layton, Blackpool, tragically died at Blackpool Victoria Hospital just days after complaining of a minor headache. (Source: the Mail online | Health)
Source: the Mail online | Health - January 22, 2013 Category: Consumer Health News Source Type: news

Uncontrolled Risk Factors Put Stroke Survivors in Danger
Smoking, high blood pressure especially dangerous for those with subarachnoid hemorrhage Source: HealthDay Related MedlinePlus Pages: Brain Aneurysm, Smoking, Stroke (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - January 18, 2013 Category: Consumer Health News Source Type: news

Conrad Bain
American actor who tackled taboo subjects in the sitcom Diff'rent StrokesThe actor Conrad Bain, who has died aged 89, found fame in middle age in the sitcom Diff'rent Strokes (1978-86). As Phillip Drummond, a white millionaire who fosters, then adopts, two orphaned black brothers, Bain was the straight man to the diminutive, wisecracking Gary Coleman, who played Arnold, the younger of the two boys. When his one-time housekeeper dies, the kindly widower Drummond takes Arnold and his brother, Willis (Todd Bridges), from their Harlem ghetto to his luxury Manhattan penthouse and brings them up with his daughter, Kimberly (Dana...
Source: Guardian Unlimited Science - January 17, 2013 Category: Science Authors: Anthony Hayward Tags: The Guardian Obituaries World news Nuclear weapons Science Source Type: news

Surviving Hemorrhage Less Likely If Patients Smoke, Have High Blood Pressure, High Cholesterol
"It is particularly important for subarachnoid haemorrhage survivors to refrain from smoking and to take care of their blood pressure and cholesterol levels; apart from age, these are the primary factors behind the increased risk of mortality," explains neurosurgeon Miikka Korja from the HUCH's Neurosurgery Department together with professor Jaakko Kaprio from the University of Helsinki's Hjelt Institute... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 15, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

Smoking, high blood pressure and cholesterol can be fatal for hemorrhage survivors
(University of Helsinki) A Finnish study shows that patients who have experienced subarachnoid hemorrhage (SAH) have a highly increased risk of death due to a stroke or cerebral hemorrhage, and have double the mortality rate of the general population. The researchers state that considerably more attention should be paid to risk factors in the life of SAH survivors. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 14, 2013 Category: Global & Universal Source Type: news

Everolimus for angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis (EXIST-2): RCT
Source: Lancet Area: News Tuberous sclerosis is a rare debilitating disease affecting one in 5800 livebirths and fewer than one million people worldwide. It is associated with multiple lesions including renal angiomyolipoma, brain subependymal giant-cell astrocytomas, and pulmonary lymphangioleiomyomatosis. Angiomyolipomas are slow-growing tumours, which predispose patients to serious complications including retroperitoneal haemorrhage and impaired renal function. The condition is caused by mutations in either TSC1 or TSC2 suppressor genes, resulting in increased mTOR activity. Hence, mTOR inhibitors have a rationale for ...
Source: NeLM - News - January 11, 2013 Category: Drugs & Pharmacology Source Type: news

Should Hillary Clinton be back at work so soon after a blood clot?
A doctor on whether the US secretary of state should be taking it easy after her health scareHillary Clinton is back at work today with 12 meetings scheduled this week, just four weeks after a blood clot on the brain. What advice would I give her if she pitched up at my GP surgery in north London?Her problems apparently kicked off at the beginning of December with a nasty European tummy bug. She became so dehydrated that she fainted and banged her head. She was admitted to hospital on 30 December and diagnosed with a right transverse venous sinus thrombosis (a blood clot in the large vein that runs in the space between bra...
Source: Guardian Unlimited Science - January 7, 2013 Category: Science Authors: Ann Robinson Tags: The Guardian Blogposts World news Health & wellbeing Society Neuroscience Features Life and style Hillary Clinton Source Type: news

Summary: International Kidney Cancer Symposium
Conclusions VHL/PBRM1 mutations confirmed 3rd subtype identified and under review but appears to be mis-classified tumors.  Shows value of molecular methods rather than new mechanistic insights. Integration with survival outcome—suggests molecular detailing can be prognostic Full integrative analysis in process Preliminary data can be found at http://tcga-data.nci.hih.gov/tcga/ FoxO Transcription Factors in mTORC1- Activated Renal Tumorigenesis:  Implications for the RCC Treatment Boyi Gan, MD Anderson Cancer Center FoxO Family Transcription Factors:  mammals possess FoxO...
Source: Kidney Cancer Association - December 15, 2011 Category: Urology & Nephrology Source Type: news

Summary: International Kidney Cancer Symposium
Conclusions VHL/PBRM1 mutations confirmed 3rd subtype identified and under review but appears to be mis-classified tumors.  Shows value of molecular methods rather than new mechanistic insights. Integration with survival outcome—suggests molecular detailing can be prognostic Full integrative analysis in process Preliminary data can be found athttp://tcga-data.nci.hih.gov/tcga/ FoxO Transcription Factors in mTORC1- Activated Renal Tumorigenesis:  Implications for the RCC Treatment Boyi Gan, MD Anderson Cancer Center FoxO Family Transcription Factors:  mammals possess FoxO1, FoxO3, FoxO4 an...
Source: Kidney Cancer Association - December 15, 2011 Category: Urology & Nephrology Source Type: news

Vitamin E Increases Risk for Hemorrhagic Stroke
New research shows that vitamin E supplementation is associated with an increase in risk for hemorrhagic stroke and a decrease in risk for ischemic stroke (Source: BWH News)
Source: BWH News - November 5, 2010 Category: Hospital Management Source Type: news

Neurology: Images in Clinical Medicine
Editor: V. Dimov, M.D., Cleveland ClinicHypoglossal Nerve Palsy during Meningococcal Meningitis. NEJM, 10/2014.Absent Superficial Abdominal Reflex due to thoracic spinal cord neuromyelitis. NEJM, 05/2014.Kayser-Fleischer Rings in Wilson's Disease. NEJM, 03/2012.Perilymph Fistula Test leads to nystagmus. NEJM, 01/2012.A stray bullet in the brain - with no deficit of power, cognition, sense of touch, or speech. Lancet, 01/2012.Blindness after Fat Injections. NEJM, 12/2011.Internal-Carotid-Artery Dissection and Cranial-Nerve Palsies. NEJM, 12/2011.A Head Shot. NEJM, 12/2011.Multiple Intracranial Tuberculomas. NEJM, 10/2011.Fo...
Source: Clinical Cases and Images - August 22, 2009 Category: General Medicine Tags: Images Neurology Source Type: news

Infectious Diseases: Images in Clinical Medicine
Editor: V. Dimov, M.D., Cleveland ClinicHypoglossal Nerve Palsy during Meningococcal Meningitis. NEJM, 10/2014.Herpes Zoster Involving the S1 Dermatome. NEJM, 05/2014.Tinea Faciei. NEJM, 05/2014.Disseminated Cryptococcosis in a CLL patient. 05/2014.Scrofuloderma due to Mycobacterium tuberculosis. NEJM, 06/2012.Leonine Facies in Lepromatous Leprosy. NEJM, 04/2012.Intestinal Infestation with Ancylostoma ceylanicum. NEJM, 03/2012.Kerion celsi form of tinea capitis caused by a T-cell hypersensitivity reaction. NEJM, 03/2012.Eye can see a nest of worms! Thelazia callipaeda. Lancet, 03/2012.Madura Foot. NEJM, 01/2012.Paragonimia...
Source: Clinical Cases and Images - August 22, 2009 Category: General Medicine Tags: Images Infectious Diseases Source Type: news