NIH Director ’ s Seminar Series: The Power and Potential of the Microenvironment in Cancer Metastasis
Although genetic including epigenetic alterations are the driving events in cancer, the tumor microenvironment, the cellular and molecular changes in non-cancer cells and tissues are altered during cancer progression. The microenvironment is involved in multiple aspect of cancer progression. Tumor metastasis is a critical step in the progression of solid tumors that is associated with patient mortality, and the metastatic microenvironment is a key regulator of this process. The pre-metastatic niche is the microenvironment important for metastatic initiation that is established at distant sites in response to primary tumor ...
Source: Videocast - All Events - February 7, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
NIH Director's Seminar - Addressing evolving and emerging public health questions with descriptive epidemiology
NIH Director's Seminar Series
Well-conducted surveillance studies have long informed hypotheses related to the causes of cancer, highlighted the population-level impact of exposures and interventions and guided additional research, prevention efforts and public health resources. The Division of Cancer Epidemiology and Genetics (DCEG) at the National Cancer Institute (NCI) has been generating etiologic clues from monitoring cancer trends and mapping cancer mortality for decades. In this lecture, Dr. Shiels will describe her research program, which utilizes a combination of innovative contemporary approaches to confront high...
Source: Videocast - All Events - January 19, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
IIG Seminar - Lineage tracking in rhesus macaques: new insights into natural killer cells and tissue-resident myeloid cells.
Dr. Dunbar ’ s research focuses on understanding the process of hematopoiesis in vivo, as well as on optimizing and improving the safety of gene transfer into primary hematopoietic cells for therapeutic purposes. Her goals are synergistic: insight into the control of hematopoiesis is required to successfully manipulate and genetically modify hematopoietic cells; conversely, genetic marking of hematopoietic stem and progenitor cells has provided novel insights into lineage relationships, stem cell dynamics, and stem cell numbers in vivo that are applicable to gene therapy, stem cell transplantation, and other clinical int...
Source: Videocast - All Events - January 9, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Mammalian DNases and their role in the tug of war between Staphylococcus aureus and the host
Immunology Interest Group
Victor J. Torres is a microbiologist investigating how multidrug-resistant bacteria cause disease and identifying new therapies to fight and prevent infection. Torres uses a diverse range of techniques spanning genetics, molecular biology, immunology, and bioinformatics to study the bacteria Staphylococcus aureus (S. aureus). S. aureus causes a wide range of diseases, from mild skin infections to life-threatening blood infections. Highly virulent and, in some instances, resistant to antibiotics (known as methicillin-resistant S. aureus, or MRSA), S. aureus is responsible for millions of illnesses ...
Source: Videocast - All Events - January 9, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Addressing evolving and emerging public health questions with descriptive epidemiology
NIH Director's Seminar Series
Well-conducted surveillance studies have long informed hypotheses related to the causes of cancer, highlighted the population-level impact of exposures and interventions and guided additional research, prevention efforts and public health resources. The Division of Cancer Epidemiology and Genetics (DCEG) at the National Cancer Institute (NCI) has been generating etiologic clues from monitoring cancer trends and mapping cancer mortality for decades. In this lecture, Dr. Shiels will describe her research program, which utilizes a combination of innovative contemporary approaches to confront high...
Source: Videocast - All Events - January 3, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
NIH Director's Seminar Series: Addressing evolving and emerging public health questions with descriptive epidemiology
Well-conducted surveillance studies have long informed hypotheses related to the causes of cancer, highlighted the population-level impact of exposures and interventions and guided additional research, prevention efforts and public health resources. The Division of Cancer Epidemiology and Genetics (DCEG) at the National Cancer Institute (NCI) has been generating etiologic clues from monitoring cancer trends and mapping cancer mortality for decades. In this lecture, Dr. Shiels will describe her research program, which utilizes a combination of innovative contemporary approaches to confront high-impact public health question...
Source: Videocast - All Events - December 29, 2022 Category: General Medicine Tags: Upcoming Events Source Type: video
NIH-FDA Immunology Interest Group 1.18.23
Victor J. Torres is a microbiologist investigating how multidrug-resistant bacteria cause disease and identifying new therapies to fight and prevent infection. Torres uses a diverse range of techniques spanning genetics, molecular biology, immunology, and bioinformatics to study the bacteria Staphylococcus aureus (S. aureus). S. aureus causes a wide range of diseases, from mild skin infections to life-threatening blood infections. Highly virulent and, in some instances, resistant to antibiotics (known as methicillin-resistant S. aureus, or MRSA), S. aureus is responsible for millions of illnesses and tens of thousands of d...
Source: Videocast - All Events - December 13, 2022 Category: General Medicine Tags: Upcoming Events Source Type: video
NIH Director's Seminar Series: Hypothalamic cell types and circuits that drive survival behaviors
The Aponte lab studies the role of genetically-identified neurons and their projections in behaviors that are essential for survival. Their ultimate goal is to understand how neurons in distinct hypothalamic circuits encode pain and the rewarding and addictive nature of food intake. To answer these questions, they use a combination of optogenetics, chemogenetics, electrophysiology, two- and single-photon fluorescence endomicroscopy, and behavioral assays to manipulate and measure the activity of these genetically-defined neuronal subpopulations in awake behaving mice. Recently, they showed how two of the lateral hypothalam...
Source: Videocast - All Events - December 1, 2022 Category: General Medicine Tags: Upcoming Events Source Type: video
Immunology Interest Group: Balancing tolerance and immunity downstream of the antigen receptor
This reporter serves as an in vivo sensor of both self and foreign antigen encounter, and serves to unmask enormous clonal heterogeneity among superficially uniform populations of B cells. Recent work has focused on dissecting the distinct roles of the IgM and IgD B cell receptor isotypes in regulating the immune responses of self-reactive B cells.For more information go tohttps://www.niaid.nih.gov/research/immunology-seminarsAir date: 12/7/2022 4:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - November 28, 2022 Category: General Medicine Tags: Upcoming Events Source Type: video
Julie Zikherman - Balancing tolerance and immunity downstream of the antigen receptor
This reporter serves as an in vivo sensor of both self and foreign antigen encounter, and serves to unmask enormous clonal heterogeneity among superficially uniform populations of B cells. Recent work has focused on dissecting the distinct roles of the IgM and IgD B cell receptor isotypes in regulating the immune responses of self-reactive B cells.For more information go tohttps://www.niaid.nih.gov/research/immunology-seminarsAir date: 12/7/2022 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - November 22, 2022 Category: General Medicine Tags: Upcoming Events Source Type: video
Neuroscience Seminar: Somatosensation and the Control of Movement
NIH Neuroscience Series Seminar
Over the past 15 years, the Goulding lab has been at the center of efforts to genetically identify and functionally characterize interneuron cell types in the spinal cord that are the core components of the spinal sensorimotor circuitry. We have characterized the development and specification of these cells in the embryonic and adult spinal cord in order to define the developmental mechanisms that determine key neuronal attributes such as morphology, connectivity and neurotransmitter phenotype.For more information go tohttps://research.ninds.nih.gov/seminars-events/neuroscience-seminar-serie...
Source: Videocast - All Events - November 17, 2022 Category: General Medicine Tags: Upcoming Events Source Type: video
Genetics and Functional Mechanisms of the SPTBN1 Syndrome
NIH Neuroscience Series SeminarFor more information go tohttps://research.ninds.nih.gov/seminars-events/neuroscience-seminar-seriesAir date: 1/23/2023 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - November 16, 2022 Category: General Medicine Tags: Upcoming Events Source Type: video
School of fish swims over coral reefs of Pagan
A school of fish swims over the coral reefs of Pagan. A research team is analyzing the genetics of eight coral species from the Northern Mariana Islands of Sarigan, Pagan and Maug that were selected for their reef-building ability and their ecological importance.
[Research supported in part by ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - October 28, 2022 Category: Science Source Type: video
Exosomes and Other Extracellular Particles in Liquid Biopsies: New keys to Decoding ‘ The Commotion in the Blood ’
NCI ’ s Center for Cancer Research (CCR) Grand Rounds is a lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians.
Dr. Jones received her M.D. and Ph.D. from Stanford University. She is a board-certified radiation oncologist with specialized training in radiosurgery and with graduate and postdoctoral training in both cancer biology and general immunology.
Dr. Jones positionally cloned the TIM gene family and demonstrated the genetic association between TIMs and immune response profiles. As a radiation oncologist, her curr...
Source: Videocast - All Events - October 24, 2022 Category: General Medicine Tags: Upcoming Events Source Type: video
Collecting a coral sample from the caldera of Maug Island
University of Guam Assistant Professor Sarah Lemer collects a coral sample from the caldera of Maug Island as part of a first-time study on the genetics of corals from the Northern Mariana Islands of Sarigan, Pagan and Maug.
[Research supported in part by the U.S. National Science ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - October 10, 2022 Category: Science Source Type: video
