Julie Zikherman - Balancing tolerance and immunity downstream of the antigen receptor

This reporter serves as an in vivo sensor of both self and foreign antigen encounter, and serves to unmask enormous clonal heterogeneity among superficially uniform populations of B cells. Recent work has focused on dissecting the distinct roles of the IgM and IgD B cell receptor isotypes in regulating the immune responses of self-reactive B cells.For more information go tohttps://www.niaid.nih.gov/research/immunology-seminarsAir date: 12/7/2022 3:00:00 PM
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