NCCIH Lecture: Watch Your Step, There Is New Chemistry Everywhere
NCCIH Integrative Medicine Research Lecture
The characterization of biologically active small molecules (natural products) produced by easily cultured bacteria has been a rewarding avenue for identifying novel therapeutics. The characterization of biologically active small molecules (natural products) produced by easily cultured bacteria has been a rewarding avenue for identifying novel therapeutics, as well as gaining insights into how bacteria interact with the world around them. Large-scale sequencing of bacterial genomic and metagenomic DNA indicates that the traditional pure culture – based approach to studying bact...
Source: Videocast - All Events - February 21, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Autoantigens and autoimmunity: a bedside to bench and back again story
NIH Director's Wednesday Afternoon Lecture Series
Noncoding RNAs play critical roles in the metabolism of all cells. The Wolin laboratory studies how noncoding RNAs function, how cells recognize and degrade defective noncoding RNAs, and how failure to degrade these RNAs affects cell function and contributes to human disease. Their studies revealed new mechanisms by which defective RNAs are targeted for degradation and new classes of noncoding RNAs. Most recently, their work has contributed to a novel theory for how the autoimmune disease systemic lupus erythematosus may be triggered in genetically susceptible individuals.A...
Source: Videocast - All Events - February 4, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Pediatric immune diseases, all genetics?
NIH Director ’ s Wednesday Afternoon Lecture Series
Dr. Fischer is interested in understanding how genetic errors cause vulnerability to microorganisms, autoimmunity, inflammation and allergy, with the dual goal to decipher in vivo immunity in humans and to correct its defects.Air date: 2/20/2019 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - February 4, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
CC Grand Rounds: 1) Severe Combined Immune Deficiency in the Newborn Screening Era: Genetic Landscape and Current Challenges and 2) Update on Clinical Outcome of Gene Therapy for X-linked Severe Combined Immune Deficiency
For more information go tohttp://www.cc.nih.gov/about/news/grcurrent.htmlAir date: 2/27/2019 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - February 4, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Interventional Pharmacoeconomics: A New Discipline for a Cost-Constrained Environment
Dr. Ratain ’ s research focuses on the development of new oncology drugs, and developing diagnostic tests in order to create individualized anticancer therapies based on each person ’ s genetic makeup. He is an international leader in phase I clinical trials, pharmacogenetics and clinical trial methodology. He has more than 260 original publications, leads the University of Chicago ’ s phase I oncology trials program, serves as director of the Center for Personalized Therapeutics and is Chief Hospital Pharmacologist for the University of Chicago Medical Center. Dr. Ratain is also co-chair of the Pharmacogenomics of A...
Source: Videocast - All Events - January 7, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
The social life of DNA
NIH Director ’ s Wednesday Afternoon Lecture Series
Dr. Nelson is president of the Social Science Research Council and professor of sociology at Columbia University. An award-winning scholar of science, medicine, and social inequality, her recent books include The Social Life of DNA: Race, Reparations, and Reconciliation after the Genome, Genetics and the Unsettled Past: The Collision of DNA, Race, and History, and Body and Soul: The Black Panther Party and the Fight Against Medical Discrimination. Dr. Nelson has contributed to national policy discussions on inequality, and about the social implications of new technologi...
Source: Videocast - All Events - January 7, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Corals on the Great Barrier Reef
. A recent study suggests that corals in the Great Barrier Reef have enough genetic variation to adapt to and survive rising ocean temperatures for at least another century.
More about this image
Using genetic samples and computer simulations, ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - December 11, 2018 Category: Science Source Type: video
Why sharing genetic information is vital for the future
Chief Development Officer at Finland ’s UNA Plan Pirkko Kortekangas says that data privacy is a priority, but sharing information is key when searching for medical solutions. (Source: Healthcare ITNews Videos)
Source: Healthcare ITNews Videos - December 6, 2018 Category: Information Technology Tags: Electronic Health Records (EHR, EMR) Government & amp; Policy Privacy amp; Security Source Type: video
Grantees Meeting: RFA AG-16-020 Impact of Aging on Currently Employed Animal Models (UH2-UH3 Demonstration Projects)
The Division of Aging Biology (DAB) is planning to hold a grantees meeting to report on their progress and engage in a panel discussion to gauge the state of the science and exchange viewpoints on the impact of aging in studies of diseases and conditions in laboratory animals (mice of different strains and genetic modifications). Grantees are in the UH3 phase of the awards. They will discuss the aging components of their studies as derived from human conditions, review preliminary findings in their respective animal models and participate in a panel discussion on outcomes and ways to optimize exposure and impact of their f...
Source: Videocast - All Events - November 29, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
Endoplasmic reticulum and immunometabolic homeostasis
NIH Director's Wednesday Afternoon Lecture Series – Special Tuesday Lecture
The major interest of Dr. Hotamisligil's laboratory is to study the regulatory pathways, which control glucose and lipid metabolism. His lab's biochemical and genetic studies focus on signal transduction using cultured mammalian cells as well as transgenic animals to identify specific abnormalities in these pathways, which are involved in human metabolic and inflammatory diseases including obesity, diabetes, fatty liver disease, atherosclerosis, and asthma.For more information go tohttps://oir.nih.gov/walsAir date: 11/13/2018 3:00:00 PM (Source: ...
Source: Videocast - All Events - November 9, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
CC Grand Rounds: Clinicopathologic Grand Rounds: When “ Lethal ” Genetic Diseases of Infancy Are Diagnosed in Adulthood
CC Grand Rounds: Clinicopathologic Grand Rounds: When “ Lethal ” Genetic Diseases of Infancy Are Diagnosed in AdulthoodFor more information go tohttp://www.cc.nih.gov/news/about/grcurrent.htmlAir date: 11/28/2018 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - November 6, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
Secondary Genomics Findings Service
Discussion: Improving Support for Clinical Research at the NIH
24 April 2017: The NIH Office of Research Support and Compliance (ORSC) – an Update
15 May 2017: News from the OHSRP: Informed Consent and Requests for Determination
16 October 2017: Investigational Treatments and Emerging Medicines: A Regulatory Perspective
20 November 2017: An Update on IRB Reorganization: A Panel Discussion
18 December 2017: Technology Transfer Agreements for Sharing Human Materials and Data: Policies and Procedures
19 March 2018: Common Rule Issues with Tissues
16 April 2018: The NIH IRB Consolidation and iRIS Transition
21 May 20...
Source: Videocast - All Events - November 6, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
Maurice B. Burg Lecture: Insights into Human Hypertension and Renal Physiology from Human Genetics and Genomics
Maurice B. Burg Lecture 2018: Insights into Human Hypertension and Renal Physiology from Human Genetics and Genomics by Dr. Richard P. Lifton MD, PhD of Rockefeller UniversityAir date: 10/29/2018 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - October 26, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
Surveillance of Core Cellular Pathways in C. elegans for Pathogen Assaults
CCR Eminent Lectures
The Ruvkun lab uses C. elegans molecular genetics and genomics to study miRNA and RNAi pathways. Using genetic and RNA interference approaches, we have identified many genes that positively or negatively regulate RNAi and microRNA pathways. These genes reveal the trajectory of siRNAs and miRNAs as they target mRNAs, as well as components that may be developed as drug targets to enhance RNAi in mammals.
Over the past decade, we discovered that like mammals, C. elegans uses an insulin signaling pathway to control its metabolism and longevity. This analysis has revealed striking congruence of molecular me...
Source: Videocast - All Events - October 18, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
How mothers give the best and enough mitochondria
NIH Directors Seminar Series
Dr. Xu ’ s Laboratory of Molecular Genetics, Systems Biology Center, NHLBI is interested in the basic mechanism guiding the transmission of our second genome- mitochondrial DNA. Mutations in mitochondrial genome have emerged as important factors compromising human health. Although mitochondrial genome is prone to accumulating mutations due to the high spontaneous mutation frequency and a lack of repair mechanisms, the crippling mitochondrial mutation is exceedingly rare in populations. It is puzzling how mothers are able to restrict the transmission of damaging mutations to the next generatio...
Source: Videocast - All Events - October 10, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
