OHSRP Education Series: The NIH Genomic Data Sharing Policy: applicability to IRP investigators; components; and required protocol and consent content
The next OHSRP Education Series session will be held on Tuesday, December 1st from 3-4 PM via live NIH videocast at https://videocast.nih.gov/ and will be archived
During this session, Kathleen Calzone, PhD, RN, AGN-BC, FAAN, will present The NIH Genomic Data Sharing Policy: applicability to the IRP; components; and required protocol and consent content. Dr. Calzone is a Research Geneticist in the Genetics Branch of the Center for Cancer Research at the National Cancer Institute. She is also the National Institutes of Health Genomic Data Sharing Policy Genomic Program Administrator for the NCI Center for Cancer Research.
O...
Source: Videocast - All Events - November 17, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Gaucher Disease: How a Rare Disease Provides a Window into Common Neurodegenerative Disorders
WALS Astute Clinician Lecture
The speaker, Dr. Ellen Sidransky, is the Branch Chief of the Medical Genetics Branch and is a pediatrician and geneticist in the National Human Genome Research Institute at National Institutes of Health (NIH). Her research interests include both clinical and basic aspects of Gaucher disease and Parkinson disease, studies of genotype/phenotype correlation and genetic modifiers, insights from mouse models, and novel treatment strategies. She played a lead role in establishing the association between glucocerebrosidase and parkinsonism. The author of over 200 publications, she continues to focus ...
Source: Videocast - All Events - October 20, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Genetic Studies Illuminating Pathways Important for Controlling COVID Disease
We are interested in new inherited defects of innate immunity that can cause increased susceptibility to virus infections, especially those targeting the respiratory tract. One example is our discovery of human MDA5 deficiency in a patient who had recurrent severe rhinovirus and other respiratory viruses. The patient ’ s loss of MDA5 demonstrated the physiological importance of this cytosolic viral nucleic acid sensor for immunity against the common cold virus. The extent to which MDA5 physiologically contributes in humans to protect against other respiratory viruses is being studied. For more information about this rese...
Source: Videocast - All Events - October 5, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
3D rendering of genetically targeted chemical assembly of functional materials
The golden color in this 3D rendering depicts biocompatible materials attached to neurons, materials deposited using a process called genetically targeted chemical assembly (GTCA). In GTCA, researchers use genetic information to target cells and precisely deposit polymers, sparing the neighboring ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - October 1, 2020 Category: Science Source Type: video
Ethical & Regulatory Aspects of Clinical Research Session 4: Genetics
The Department of Bioethics offers this seven week course annually each fall. The course is designed to provide an overview of the important issues in the ethics of human subject research for clinical investigators and others who participate in the conduct of research and is open to the entire NIH community as well as to those from outside NIH. Topics include the history of human subject research ethics, principles and guidelines, study design, subject recruitment, informed consent, and international research. The course is open to the entire NIH community as well as to those from outside NIH. The recommended textbook is E...
Source: Videocast - All Events - September 14, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Human antibody responses to SARS-CoViD-2
NIH Director's Wednesday Afternoon Lecture Series
Annual William E. Paul Lecture – – Dr. Nussenzweig ’ s laboratory studies the molecular aspects of the immune system ’ s innate and adaptive responses using a combination of biochemistry, molecular biology, and genetics. For work on adaptive immunity, he focuses on B lymphocytes and antibodies to HIV-1, while his studies of innate immunity focus on dendritic cells. His work is leading to new antibody-based therapies for infections by HIV and the novel SARS-CoV-2 coronavirus, among other viruses.For more information go tohttps://oir.nih.gov/wals/about-walsAir date: 1...
Source: Videocast - All Events - September 14, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
DNA Repair Interest Group Seminar: The Sensing and Repair of DNA Strand Breaks and Human Genetic Disease
DNA Repair Interest Group SeminarAir date: 10/20/2020 12:30:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - September 14, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
From Mechanisms to Medicines: Realizing the DREAM of an Alzheimer's Cure
NIH Director's Seminar Series
The repeated failures of disease-modifying treatments for Alzheimer ’ s disease (AD) have increased the urgency to identify novel therapeutic targets and biomarkers for AD and related dementias (ADRD). Dr. Thambisetty's Clinical and Translational Neuroscience Section has applied a systems biology approach leveraging deep molecular phenotyping by multi-OMICs methods in brain and blood in combination with multi-modal neuroimaging and epidemiological analyses to identify abnormal metabolic pathways in ADRD associated with severity of pathology and expression of clinical symptoms. These studies ...
Source: Videocast - All Events - September 2, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
NIH Director's Seminar Series
The repeated failures of disease-modifying treatments for Alzheimer ’ s disease (AD) have increased the urgency to identify novel therapeutic targets and biomarkers for AD and related dementias (ADRD). Dr. Thambisetty's Clinical and Translational Neuroscience Section has applied a systems biology approach leveraging deep molecular phenotyping by multi-OMICs methods in brain and blood in combination with multi-modal neuroimaging and epidemiological analyses to identify abnormal metabolic pathways in ADRD associated with severity of pathology and expression of clinical symptoms. These studies have added to a growing body o...
Source: Videocast - All Events - September 2, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Nucleic Acid Delivery Systems for RNA Therapy and Gene Editing
NIH COVID-19 SIG Lecture Series
High throughput, combinatorial approaches have revolutionized small-molecule drug discovery. Dan Anderson will describe his work on the combinatorial development of nanoparticulate, intracellular delivery systems for RNA therapy and gene editing. Libraries of degradable polymers and lipid-like materials have been synthesized, formulated, and screened for their ability to deliver macromolecular payloads inside of cells. These nanoformulations facilitate in vivo delivery, enabling gene suppression with small-interfering RNA, gene expression with messenger RNA, or permanent genetic editing usin...
Source: Videocast - All Events - June 5, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Genetics' part in the standard of care
2bPrecise CMO Joel Diamond, MD, says pharmacogenomics is a good entry point for providers in precision medicine, identifying the right medicine for better outcomes and patient satisfaction. (Source: Healthcare ITNews Videos)
Source: Healthcare ITNews Videos - May 14, 2020 Category: Information Technology Tags: Precision Medicine Quality and Safety Source Type: video
SGI Symposium
NINR ’ s Division of Intramural Research (DIR) will convene a half-day symposium to mark a milestone anniversary of its Summer Genetics Institute. The symposium will include keynote addresses, scientific presentations, a scientific panel discussion, and a research poster session. It will highlight SGI graduates ’ many accomplishments and showcase the positive impact of this program in accelerating genetics and genomics in nursing science.Air date: 6/22/2020 11:00:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - April 27, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
New evidence that modern humans and Neanderthals share a tangled genetic history.
New research from University at Buffalo and the Foundation for Research and Technology in Greece adds to growing evidence that our ancestors interbred with Neanderthals more often than we thought.This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - April 24, 2020 Category: Science Source Type: video
Demystifying Medicine - Sickle Cell Anemia: Treatable and/or Curable?
Demystifying Medicine Lecture Series
Although the fundamental molecular pathophysiology of sickle cell anemia was elucidated in studies of this genetic disease starting more than 70 years ago, it is only in about the last two decades that this knowledge has led to specific therapies. Indeed in the last decade serious attention has turned to the possibility of a genetic cure of this condition.
Have we finally cured sickle cell anemia? Not quite, but we may be on the cusp. Really. In a dozen clinical trials planned or underway, some at the NIH Clinical Center, researchers are applying gene therapy to cure this well-studied g...
Source: Videocast - All Events - February 27, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Clinical Neuroscience Grand Rounds: Molecular Genetics and Novel Therapeutics
Clinical Neuroscience Grand Rounds
This activity is intended for Neurologists, Neuroscientists, Neurosurgeons, Neuropsychologists, and Health Care Professionals.
This activity has been planned and implemented in accordance with the Essential Areas and polices of the Accreditation Council for Continuing Medical Education through the joint providership of the Johns Hopkins University School of Medicine and the National Institutes of Health (NIH). The Johns Hopkins University School of Medicine is accredited by the ACME to provide continuing medical education for physicians.Air date: 3/3/2020 8:30:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - February 25, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
