Viruses, Vol. 16, Pages 599: Circulation of West Nile Virus and Usutu Virus in Europe: Overview and Challenges
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West Nile Virus (WNV) and Usutu Virus (USUV) are both neurotropic mosquito-borne viruses belonging to the Flaviviridae family. These closely related viruses mainly follow an enzootic cycle involving mosquitoes as vectors and birds as amplifying hosts, but humans and other mammals can also be infected through mosquito bites. WNV was first identified in Uganda in 1937 and has since spread globally, notably in Europe, causing periodic outbreaks associated with severe cases of neuroinvasive diseases such as meningitis and encephalitis. USUV was initially isolated in 1959 in Swaziland and has also spread to Europe, primar...
Source: Viruses - April 12, 2024 Category: Virology Authors: Yannick Simonin Tags: Perspective Source Type: research
Haemorrhagic myelitis as a manifestation of MOG antibody-associated disease
We read with interest the recent article ‘MOG antibody-associated encephalitis in adult: clinical phenotypes and outcomes’ by Lee et al1 and the letter to the editor entitled ‘Acute haemorrhagic leucoencephalitis as clinical manifestation of MOG antibody-associated disease’ by Skarsta et al.2 In the first article, the authors illustrate three different phenotypes of MOG (myelin oligodendrocyte glycoprotein) antibody-associated encephalitis in 40 patients, including acute disseminated encephalomyelitis (ADEM) in 17 patients. They highlight the favourable outcome of these encephalitis cases following ...
Source: Journal of Neurology, Neurosurgery and Psychiatry - April 12, 2024 Category: Neurosurgery Authors: Ciron, J., Biotti, D., Bost, C., Bonneville, F., Marignier, R. Tags: PostScript Source Type: research
Detection of virus-specific T cells via ELISpot corroborates early diagnosis in human Borna disease virus 1 (BoDV-1) encephalitis
ConclusionThis case demonstrates that BoDV-1 ELISpot serves as additional diagnostic tool even in the first week after hospitalisation of patients with BoDV-1 encephalitis. (Source: Infection)
Source: Infection - April 12, 2024 Category: Infectious Diseases Source Type: research
Analysis of mild and severe neonatal enterovirus infections in a Chinese neonatal tertiary center: a retrospective case-control study
ConclusionWe found significant differences between mild and severe cases of neonatal enterovirus infection with respect to complications, laboratory findings, and enterovirus serotypes. It is crucial to exercise caution when newborns exhibit symptoms of sepsis, during an enterovirus outbreak. Anemia, thrombocytopenia, abnormal liver function, and coagulation dysfunction should be monitored closely as they could indicate the presence of a severe enteroviral infection. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 12, 2024 Category: Microbiology Source Type: research
Detection of virus-specific T cells via ELISpot corroborates early diagnosis in human Borna disease virus 1 (BoDV-1) encephalitis
ConclusionThis case demonstrates that BoDV-1 ELISpot serves as additional diagnostic tool even in the first week after hospitalisation of patients with BoDV-1 encephalitis. (Source: Infection)
Source: Infection - April 12, 2024 Category: Infectious Diseases Source Type: research
Fatal tick-borne encephalitis virus infection in Dalmatian puppy-dogs after putative vector independent transmission
Vet Q. 2024 Dec;44(1):1-7. doi: 10.1080/01652176.2024.2338385. Epub 2024 Apr 10.ABSTRACTIn a retrospective metatranscriptomics study, we identified tick-borne encephalitis virus (TBEV) to be the causative agent for a fatal non-suppurative meningoencephalitis in a three-week-old Dalmatian puppy in Switzerland. Further investigations showed that the two other littermates with similar signs and pathological lesions were also positive for TBEV. By using an unbiased approach of combining high-throughput sequencing (HTS) and bioinformatics we were able to solve the etiology and discover an unusual case of TBEV in three young pup...
Source: Veterinary Quarterly - April 10, 2024 Category: Veterinary Research Authors: Kara L D Dawson Giuliana Rosato Simone Egloff Carole Burgener Anna Oevermann Paula Grest Monika Hilbe Torsten Seuberlich Source Type: research
Left dural carotid cavernous fistula mimicking an inflammatory process: A case report
Radiol Case Rep. 2024 Apr 5;19(6):2558-2560. doi: 10.1016/j.radcr.2024.03.021. eCollection 2024 Jun.ABSTRACTA female in her 70s presented with altered mental status, left eye pain, ophthalmalgia, and diplopia following a fall. Brain MRI demonstrated contrast-enhancing left peri-insular T2 hyperintense changes that was read as possible herpes simplex encephalitis by neuroradiology. Cerebral angiogram revealed a Barrow Type D left sided carotid cavernous fistula. The patient was subsequently treated with endovascular transvenous coil embolization of the left cavernous sinus resulting in complete occlusion of the fistula. The...
Source: Herpes - April 10, 2024 Category: Infectious Diseases Authors: Annika K Oie Amanda A Herrmann Michael H Rosenbloom Source Type: research
Fatal tick-borne encephalitis virus infection in Dalmatian puppy-dogs after putative vector independent transmission
Vet Q. 2024 Dec;44(1):1-7. doi: 10.1080/01652176.2024.2338385. Epub 2024 Apr 10.ABSTRACTIn a retrospective metatranscriptomics study, we identified tick-borne encephalitis virus (TBEV) to be the causative agent for a fatal non-suppurative meningoencephalitis in a three-week-old Dalmatian puppy in Switzerland. Further investigations showed that the two other littermates with similar signs and pathological lesions were also positive for TBEV. By using an unbiased approach of combining high-throughput sequencing (HTS) and bioinformatics we were able to solve the etiology and discover an unusual case of TBEV in three young pup...
Source: Veterinary Quarterly - April 10, 2024 Category: Veterinary Research Authors: Kara L D Dawson Giuliana Rosato Simone Egloff Carole Burgener Anna Oevermann Paula Grest Monika Hilbe Torsten Seuberlich Source Type: research
Herpes Zoster and Varicella Encephalitis Following the Recombinant Zoster Vaccine
Cutis. 2024 Feb;113(2):E14-E15. doi: 10.12788/cutis.0961.NO ABSTRACTPMID:38593103 | DOI:10.12788/cutis.0961 (Source: Herpes)
Source: Herpes - April 9, 2024 Category: Infectious Diseases Authors: Mallory Pane Catherine Harrell Stuart C Pickell Source Type: research
Acute Encephalitis Syndrome in Children and Adolescents: A Five-Year Descriptive Study From South India
CONCLUSIONS: A definitive diagnosis was obtained in about half of the children with AES. Viral (30.4%) and rickettsial infections (22%) were the common etiologies identified. Poor outcome was observed in 32 % of patients.PMID:38584403 (Source: Indian Pediatrics)
Source: Indian Pediatrics - April 8, 2024 Category: Pediatrics Authors: Betsy Rebecca Maya Thomas Asha Mary Abraham Sangeetha Yoganathan Ebor Jacob Sathish Kumar Anna Simon Anitha Jasper Winsley Rose Source Type: research
Acute Encephalitis Syndrome in Children and Adolescents: A Five-Year Descriptive Study From South India
CONCLUSIONS: A definitive diagnosis was obtained in about half of the children with AES. Viral (30.4%) and rickettsial infections (22%) were the common etiologies identified. Poor outcome was observed in 32 % of patients.PMID:38584403 (Source: Indian Pediatrics)
Source: Indian Pediatrics - April 8, 2024 Category: Pediatrics Authors: Betsy Rebecca Maya Thomas Asha Mary Abraham Sangeetha Yoganathan Ebor Jacob Sathish Kumar Anna Simon Anitha Jasper Winsley Rose Source Type: research
Acute Encephalitis Syndrome in Children and Adolescents: A Five-Year Descriptive Study From South India
CONCLUSIONS: A definitive diagnosis was obtained in about half of the children with AES. Viral (30.4%) and rickettsial infections (22%) were the common etiologies identified. Poor outcome was observed in 32 % of patients.PMID:38584403 (Source: Indian Pediatrics)
Source: Indian Pediatrics - April 8, 2024 Category: Pediatrics Authors: Betsy Rebecca Maya Thomas Asha Mary Abraham Sangeetha Yoganathan Ebor Jacob Sathish Kumar Anna Simon Anitha Jasper Winsley Rose Source Type: research
SARS-CoV-2 causes dysfunction in human iPSC-derived brain microvascular endothelial cells potentially by modulating the Wnt signaling pathway
ConclusionThese findings suggest that SARS-CoV-2 infection causes BBB dysfunction via Wnt signaling. Thus, iPSC-BMELCs are a useful in vitro model for elucidating COVID-19 neuropathology and drug development. (Source: Fluids and Barriers of the CNS)
Source: Fluids and Barriers of the CNS - April 8, 2024 Category: Neuroscience Source Type: research
The First Record of Omsk Hemorrhagic Fever Virus and Tick-Borne Encephalitis Virus of Baltic Lineage from the Kemerovo Region of Russia
Vector-Borne and Zoonotic Diseases, Ahead of Print. (Source: Vector-Borne and Zoonotic Diseases)
Source: Vector-Borne and Zoonotic Diseases - April 8, 2024 Category: Infectious Diseases Authors: Sergey Y. Kovalev Viktoriya Y. Okulovskaya Source Type: research
