Anti-NMDA Receptor Encephalitis, Human Papillomavirus, and microRNA
CONCLUSION: This finding suggests that in cases where individuals receiving HPV vaccination experience psychiatric or neurological symptoms, it should be considered to diagnose anti-NMDA receptor encephalitis, given the exclusion of other possible complications.PMID:38549528 | DOI:10.2174/0109298673264615231124072130 (Source: Current Medicinal Chemistry)
Source: Current Medicinal Chemistry - March 29, 2024 Category: Chemistry Authors: Hsiuying Wang Source Type: research

Rapamycin alleviates mitochondrial dysfunction in anti-NMDAR encephalitis mice
Int Immunopharmacol. 2024 Mar 28;132:111910. doi: 10.1016/j.intimp.2024.111910. Online ahead of print.ABSTRACTAnti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is one of the most prevalent forms of autoimmune encephalitis, characterized by a series of neurological and psychiatric symptoms, including cognitive impairment, seizures and psychosis. The underlying mechanism of anti-NMDAR encephalitis remains unclear. In the current study, the mouse model of anti-NMDAR encephalitis with active immunization was performed. We first uncovered excessive mitochondrial fission in the hippocampus and temporal cortex of anti-NMDAR...
Source: International Immunopharmacology - March 29, 2024 Category: Allergy & Immunology Authors: Liangbo Kong Xiaxin Yang Anqi Sun Xue Yang Xiuhe Zhao Shengjun Wang Source Type: research

Anti-NMDA Receptor Encephalitis, Human Papillomavirus, and microRNA
CONCLUSION: This finding suggests that in cases where individuals receiving HPV vaccination experience psychiatric or neurological symptoms, it should be considered to diagnose anti-NMDA receptor encephalitis, given the exclusion of other possible complications.PMID:38549528 | DOI:10.2174/0109298673264615231124072130 (Source: Current Medicinal Chemistry)
Source: Current Medicinal Chemistry - March 29, 2024 Category: Chemistry Authors: Hsiuying Wang Source Type: research

Rapamycin alleviates mitochondrial dysfunction in anti-NMDAR encephalitis mice
Int Immunopharmacol. 2024 Mar 28;132:111910. doi: 10.1016/j.intimp.2024.111910. Online ahead of print.ABSTRACTAnti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is one of the most prevalent forms of autoimmune encephalitis, characterized by a series of neurological and psychiatric symptoms, including cognitive impairment, seizures and psychosis. The underlying mechanism of anti-NMDAR encephalitis remains unclear. In the current study, the mouse model of anti-NMDAR encephalitis with active immunization was performed. We first uncovered excessive mitochondrial fission in the hippocampus and temporal cortex of anti-NMDAR...
Source: International Immunopharmacology - March 29, 2024 Category: Allergy & Immunology Authors: Liangbo Kong Xiaxin Yang Anqi Sun Xue Yang Xiuhe Zhao Shengjun Wang Source Type: research

Anti-NMDA Receptor Encephalitis, Human Papillomavirus, and microRNA
CONCLUSION: This finding suggests that in cases where individuals receiving HPV vaccination experience psychiatric or neurological symptoms, it should be considered to diagnose anti-NMDA receptor encephalitis, given the exclusion of other possible complications.PMID:38549528 | DOI:10.2174/0109298673264615231124072130 (Source: Current Medicinal Chemistry)
Source: Current Medicinal Chemistry - March 29, 2024 Category: Chemistry Authors: Hsiuying Wang Source Type: research

Anti-NMDA Receptor Encephalitis, Human Papillomavirus, and microRNA
CONCLUSION: This finding suggests that in cases where individuals receiving HPV vaccination experience psychiatric or neurological symptoms, it should be considered to diagnose anti-NMDA receptor encephalitis, given the exclusion of other possible complications.PMID:38549528 | DOI:10.2174/0109298673264615231124072130 (Source: Current Medicinal Chemistry)
Source: Current Medicinal Chemistry - March 29, 2024 Category: Chemistry Authors: Hsiuying Wang Source Type: research

A Specific Pattern of Routine Cerebrospinal Fluid Parameters Might Help to Identify Cases of West Nile Virus Neuroinvasive Disease
CONCLUSIONS: Cases with WNV ME showed a specific pattern of routine CSF parameters and demographic data that allowed for their identification with good accuracy. These findings might help to guide the diagnostic workup in cases with viral ME, in particular allowing the timely identification of cases with ME due to WNV.PMID:38543707 | PMC:PMC10974314 | DOI:10.3390/v16030341 (Source: Herpes)
Source: Herpes - March 28, 2024 Category: Infectious Diseases Authors: Johann Otto Pelz Christoph M ühlberg Isabel Friedrich Lorenz Weidhase Silke Zimmermann Melanie Maier Corinna Pietsch Source Type: research

Two Waves of Specific B Cell Memory Immunoreconstruction Observed in Anti-HHV1-3 IgG Kinetics after Hematopoietic Stem Cell Transplantation
CONCLUSIONS: As is typical for infancy, the kinetics of the IgG level is unique after HSCT (the decline phase is first). Host microbiome factors (e.g., HHV1-3-serostatus) should be taken into account to predict risk of non-relapse mortality and survival after HSCT. The levels of specific antibodies help in predicting prognoses and improve disease management. A lack of differentiation and the confusing bias of the assessor (i.e., observer selection bias) are the main obstacles in statistical HHV1-3 research. Such time-lapse case studies may be the first to build evidence of a pathway and an association between immune parame...
Source: Herpes - March 28, 2024 Category: Infectious Diseases Authors: Przemyslaw Zdziarski Andrzej Gamian Source Type: research

Disseminated Enterovirus Infection in a Patient Affected by Follicular Lymphoma Treated with Obinutuzumab: A Case Report and a Narrative Review of the Literature
Conclusions: onco-hematological patients who receive immune-chemotherapy with a combination of treatments which depress adaptative immunity, which includes the antiCD20 obinutuzumab, could be at higher risk of disseminated EV infection, including CNS and cardiac involvement.PMID:38541221 | DOI:10.3390/medicina60030495 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Tommaso Lupia Silvia Corcione Elena Staffilano Roberta Bosio Antonio Curtoni Alessandro Busca Francesco Giuseppe De Rosa Source Type: research

Disseminated Enterovirus Infection in a Patient Affected by Follicular Lymphoma Treated with Obinutuzumab: A Case Report and a Narrative Review of the Literature
Conclusions: onco-hematological patients who receive immune-chemotherapy with a combination of treatments which depress adaptative immunity, which includes the antiCD20 obinutuzumab, could be at higher risk of disseminated EV infection, including CNS and cardiac involvement.PMID:38541221 | PMC:PMC10972032 | DOI:10.3390/medicina60030495 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Tommaso Lupia Silvia Corcione Elena Staffilano Roberta Bosio Antonio Curtoni Alessandro Busca Francesco Giuseppe De Rosa Source Type: research

Disseminated Enterovirus Infection in a Patient Affected by Follicular Lymphoma Treated with Obinutuzumab: A Case Report and a Narrative Review of the Literature
Conclusions: onco-hematological patients who receive immune-chemotherapy with a combination of treatments which depress adaptative immunity, which includes the antiCD20 obinutuzumab, could be at higher risk of disseminated EV infection, including CNS and cardiac involvement.PMID:38541221 | PMC:PMC10972032 | DOI:10.3390/medicina60030495 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Tommaso Lupia Silvia Corcione Elena Staffilano Roberta Bosio Antonio Curtoni Alessandro Busca Francesco Giuseppe De Rosa Source Type: research

Disseminated Enterovirus Infection in a Patient Affected by Follicular Lymphoma Treated with Obinutuzumab: A Case Report and a Narrative Review of the Literature
Conclusions: onco-hematological patients who receive immune-chemotherapy with a combination of treatments which depress adaptative immunity, which includes the antiCD20 obinutuzumab, could be at higher risk of disseminated EV infection, including CNS and cardiac involvement.PMID:38541221 | PMC:PMC10972032 | DOI:10.3390/medicina60030495 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Tommaso Lupia Silvia Corcione Elena Staffilano Roberta Bosio Antonio Curtoni Alessandro Busca Francesco Giuseppe De Rosa Source Type: research

Disseminated Enterovirus Infection in a Patient Affected by Follicular Lymphoma Treated with Obinutuzumab: A Case Report and a Narrative Review of the Literature
Conclusions: onco-hematological patients who receive immune-chemotherapy with a combination of treatments which depress adaptative immunity, which includes the antiCD20 obinutuzumab, could be at higher risk of disseminated EV infection, including CNS and cardiac involvement.PMID:38541221 | PMC:PMC10972032 | DOI:10.3390/medicina60030495 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Tommaso Lupia Silvia Corcione Elena Staffilano Roberta Bosio Antonio Curtoni Alessandro Busca Francesco Giuseppe De Rosa Source Type: research