Regional cerebral blood flow in a patient with asystole episodes associated with anti-NMDA receptor encephalitis
Neurocase. 2024 Apr 27:1-4. doi: 10.1080/13554794.2024.2348221. Online ahead of print.ABSTRACTAnti-N-methyl-D-aspartate (NMDA) receptor encephalitis is a rare and severe autoimmune encephalitis that displays neuropsychiatric symptoms and autonomic instability, e.g., hypoventilation and cardiac arrhythmia. Severe arrhythmia including asystole associated with this encephalitis is rare. Several causes have been suggested. Nevertheless, no report of the literature has described examination by functional brain imaging of a patient with asystole during anti-NMDA receptor encephalitis. This case is that of a 34-year-old woman dia...
Source: Neurocase - April 27, 2024 Category: Neurology Authors: Gaku Aboshi Takaki Akahane Keisuke Noto Ryota Kobayashi Masakazu Akiho Akihito Suzuki Source Type: research
Neonatal herpes: case series in two obstetric centres over a 10-year period (2013-2023), France
Conclusion: This case series confirms that neonates at risk for HSV disease and poor outcome are those born to HSV-seronegative mothers, preterm infants, and those who received acyclovir after onset of symptoms (mainly because mothers did not present evidence of acute HSV infection). Our study confirms the major role of HSV-1 and the frequency of its early post-natal acquisition. What is known: • Neonatal herpes simplex virus infection is rare but motality and morbidity rates are high after disseminted disease and encephalitis. National recommendations exist worldwide but mangement of this disease is not always easy. Wha...
Source: Herpes - April 27, 2024 Category: Infectious Diseases Authors: Elise Bouthry Vincent Portet-Sulla Melek Manai Bouokazi Claire P érillaud-Dubois Fran çois-Charles Javaugue Laure Jule Claire Boithias Nolwenn Le Sach é Mostafa Mokhtari Diane Carri ère Louise Sonnier Rafik Benammar Alexandra Letourneau Alexandre J Vi Source Type: research
Herpes simplex encephalitis in France: incidence, 6-month rehospitalizations and mortality
CONCLUSION: In France, the incidence of hospitalizations for HSE was 2.3 per 1,000,000 inhabitants with more than half of the patients admitted in ICU and a 6-month in-hospital mortality about 16.5%. This real-life update on the characteristics and severe outcomes of the disease raises awareness among care practitioners, of the serious nature of the disease, and thus can lead to higher vigilance.PMID:38678152 | DOI:10.1007/s15010-024-02272-3 (Source: Herpes)
Source: Herpes - April 27, 2024 Category: Infectious Diseases Authors: Ambre Sauvage Emeline Laurent Christophe Gaborit Antoine Guillon Leslie Grammatico-Guillon Source Type: research
A Review of the Association between Infections, Seizures, and Drugs
CONCLUSION: Due to changes in drug metabolism, co-administration of antiseizure drugs and antibiotics may lead to an enhanced risk of seizures. In patients with neurocysticercosis, cerebral malaria, viral encephalitis, bacterial meningitis, tuberculosis, and human immunodeficiency virus, the evidence-based study recommended different mechanisms mediating epileptogenic properties of toxins and drugs.PMID:38676494 | DOI:10.2174/0118715249288932240416071636 (Source: Herpes)
Source: Herpes - April 27, 2024 Category: Infectious Diseases Authors: Zahra Tolou-Ghamari Source Type: research
Human Herpes Virus-6 (HHV-6) Reactivation after Hematopoietic Cell Transplant and Chimeric Antigen Receptor (CAR)- T Cell Therapy: A Shifting Landscape
Viruses. 2024 Mar 24;16(4):498. doi: 10.3390/v16040498.ABSTRACTHHV-6B reactivation affects approximately half of all allogeneic hematopoietic cell transplant (HCT) recipients. HHV-6B is the most frequent infectious cause of encephalitis following HCT and is associated with pleiotropic manifestations in this setting, including graft-versus-host disease, myelosuppression, pneumonitis, and CMV reactivation, although the causal link is not always clear. When the virus inserts its genome in chromosomes of germ cells, the chromosomally integrated form (ciHHV6) is inherited by offspring. The condition of ciHHV6 is characterized b...
Source: Herpes - April 27, 2024 Category: Infectious Diseases Authors: Eleftheria Kampouri Guy Handley Joshua A Hill Source Type: research
Regional cerebral blood flow in a patient with asystole episodes associated with anti-NMDA receptor encephalitis
Neurocase. 2024 Apr 27:1-4. doi: 10.1080/13554794.2024.2348221. Online ahead of print.ABSTRACTAnti-N-methyl-D-aspartate (NMDA) receptor encephalitis is a rare and severe autoimmune encephalitis that displays neuropsychiatric symptoms and autonomic instability, e.g., hypoventilation and cardiac arrhythmia. Severe arrhythmia including asystole associated with this encephalitis is rare. Several causes have been suggested. Nevertheless, no report of the literature has described examination by functional brain imaging of a patient with asystole during anti-NMDA receptor encephalitis. This case is that of a 34-year-old woman dia...
Source: Neurocase - April 27, 2024 Category: Neurology Authors: Gaku Aboshi Takaki Akahane Keisuke Noto Ryota Kobayashi Masakazu Akiho Akihito Suzuki Source Type: research
Severe Tick-Borne Encephalitis (TBE) in a Patient with X-Linked Agammaglobulinemia; Treatment with TBE Virus IgG Positive Plasma, Clinical Outcome and T Cell Responses
ConclusionTBEV IgG-positive plasma given to an XLA patient with TBE without evident adverse reactions may have contributed to a positive clinical outcome. Similar approaches could offer a promising foundation for researching therapeutic options for patients with humoral immunodeficiencies. Importantly, a robust CD8+ T cell response was observed after infection despite the lack of B cells and indicates that these patients can clear acute viral infections and could benefit from future vaccination programs. (Source: Journal of Clinical Immunology)
Source: Journal of Clinical Immunology - April 27, 2024 Category: Allergy & Immunology Source Type: research
A case of NMDAR Encephalitis with muscular pain as the main presentation
Persistent somatoform pain disorder (PSPD) is often the initial diagnosis in patients seeking treatment in psychiatric departments, making it challenging to consider organic nervous system diseases. However, a... (Source: BMC Neurology)
Source: BMC Neurology - April 27, 2024 Category: Neurology Authors: Baizhu Li and Xiuli Shang Tags: Case Report Source Type: research
Case Series of Jamestown Canyon Virus Infections with Neurologic Outcomes, Canada, 2011-2016
We describe a case series of confirmed JCV-mediated neuroinvasive disease among persons from the provinces of British Columbia, Alberta, Quebec, and Nova Scotia, Canada, during 2011-2016. We highlight the case definitions, epidemiology, unique features and clinical manifestations, disease seasonality, and outcomes for those cases. Two of the patients (from Quebec and Nova Scotia) might have acquired JCV infections during travel to the northeastern region of the United States. This case series collectively demonstrates JCV's wide distribution and indicates the need for increased awareness of JCV as the underlying cause of m...
Source: Emerging Infectious Diseases - April 26, 2024 Category: Infectious Diseases Authors: Vanessa Meier-Stephenson Michael A Drebot Kristina Dimitrova Melanie DiQuinzio Kevin Fonseca David Forrest Todd Hatchette Muhammad Morshed Glen Patriquin Guillaume Poliquin Lynora Saxinger Bouchra Serhir Raymond Tellier Christian Therrien Linda Vrbova Hei Source Type: research
Case Series of Jamestown Canyon Virus Infections with Neurologic Outcomes, Canada, 2011-2016
We describe a case series of confirmed JCV-mediated neuroinvasive disease among persons from the provinces of British Columbia, Alberta, Quebec, and Nova Scotia, Canada, during 2011-2016. We highlight the case definitions, epidemiology, unique features and clinical manifestations, disease seasonality, and outcomes for those cases. Two of the patients (from Quebec and Nova Scotia) might have acquired JCV infections during travel to the northeastern region of the United States. This case series collectively demonstrates JCV's wide distribution and indicates the need for increased awareness of JCV as the underlying cause of m...
Source: Emerging Infectious Diseases - April 26, 2024 Category: Infectious Diseases Authors: Vanessa Meier-Stephenson Michael A Drebot Kristina Dimitrova Melanie DiQuinzio Kevin Fonseca David Forrest Todd Hatchette Muhammad Morshed Glen Patriquin Guillaume Poliquin Lynora Saxinger Bouchra Serhir Raymond Tellier Christian Therrien Linda Vrbova Hei Source Type: research
Case Series of Jamestown Canyon Virus Infections with Neurologic Outcomes, Canada, 2011-2016
We describe a case series of confirmed JCV-mediated neuroinvasive disease among persons from the provinces of British Columbia, Alberta, Quebec, and Nova Scotia, Canada, during 2011-2016. We highlight the case definitions, epidemiology, unique features and clinical manifestations, disease seasonality, and outcomes for those cases. Two of the patients (from Quebec and Nova Scotia) might have acquired JCV infections during travel to the northeastern region of the United States. This case series collectively demonstrates JCV's wide distribution and indicates the need for increased awareness of JCV as the underlying cause of m...
Source: Emerging Infectious Diseases - April 26, 2024 Category: Infectious Diseases Authors: Vanessa Meier-Stephenson Michael A Drebot Kristina Dimitrova Melanie DiQuinzio Kevin Fonseca David Forrest Todd Hatchette Muhammad Morshed Glen Patriquin Guillaume Poliquin Lynora Saxinger Bouchra Serhir Raymond Tellier Christian Therrien Linda Vrbova Hei Source Type: research
Case report: Shingles-associated probable Bickerstaff brainstem encephalitis with IgM anti-sulfatide positivity
CONCLUSIONS: We emphasize the importance of a careful medical history and assessment of clinical symptoms, performing MRI, testing autoimmune antibodies for rapid diagnosis, and ruling out differential diagnoses. Further studies involving more patients with BBE with IgM anti-sulfatide autoantibodies will increase the understanding of the clinical characteristics and advance the diagnosis and treatment of this syndrome. Meanwhile, it is crucial for dermatologists to know about this severe neurological complication following shingles.PMID:38660303 | PMC:PMC11041370 | DOI:10.3389/fimmu.2024.1358886 (Source: Herpes)
Source: Herpes - April 25, 2024 Category: Infectious Diseases Authors: Xiaoxue Fu Qianli Zhan Linjie Zhang Xiaoyan Tian Source Type: research
Case report: Shingles-associated probable Bickerstaff brainstem encephalitis with IgM anti-sulfatide positivity
CONCLUSIONS: We emphasize the importance of a careful medical history and assessment of clinical symptoms, performing MRI, testing autoimmune antibodies for rapid diagnosis, and ruling out differential diagnoses. Further studies involving more patients with BBE with IgM anti-sulfatide autoantibodies will increase the understanding of the clinical characteristics and advance the diagnosis and treatment of this syndrome. Meanwhile, it is crucial for dermatologists to know about this severe neurological complication following shingles.PMID:38660303 | PMC:PMC11041370 | DOI:10.3389/fimmu.2024.1358886 (Source: Herpes)
Source: Herpes - April 25, 2024 Category: Infectious Diseases Authors: Xiaoxue Fu Qianli Zhan Linjie Zhang Xiaoyan Tian Source Type: research
Viruses, Vol. 16, Pages 674: Transcriptomic Investigation of the Virus Spectrum Carried by Midges in Border Areas of Yunnan Province
Mang Shi
Yun Feng
Yunnan province in China shares its borders with three neighboring countries: Myanmar, Vietnam, and Laos. The region is characterized by a diverse climate and is known to be a suitable habitat for various arthropods, including midges which are notorious for transmitting diseases which pose significant health burdens affecting both human and animal health. A total of 431,100 midges were collected from 15 different locations in the border region of Yunnan province from 2015 to 2020. These midges were divided into 37 groups according to the collection year and sampling site. These 37 groups of midges...
Source: Viruses - April 25, 2024 Category: Virology Authors: Lifen Yang Weichen Wu Sa Cai Jing Wang Guopeng Kuang Weihong Yang Juan Wang Xi Han Hong Pan Mang Shi Yun Feng Tags: Article Source Type: research
FLAMES overlaying anti-N-methyl-D-aspartate receptor encephalitis: a case report and literature review
In recent years, simultaneous or sequential occurrence of MOG antibody disease and anti-NMDAR encephalitis in the same patient has been reported with increasing frequency. Scholars refer to the overlapping occ... (Source: BMC Neurology)
Source: BMC Neurology - April 25, 2024 Category: Neurology Authors: Rimei Zhong, Xiongjin Chen, Feng Liao, Zhijun Lin, Zhijian Zhang, Yusen Chen and Lili Cui Tags: Case Report Source Type: research
